Download or read book Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension written by Toshio Nakanishi and published by Springer Nature. This book was released on 2020-02-28 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.

Download or read book Medical Pharmacology and Therapeutics E Book written by Derek G. Waller and published by Elsevier Health Sciences. This book was released on 2013-08-07 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all the pharmacology you need, from basic science pharmacology and pathophysiology, through to clinical pharmacology to therapeutics, in line with the integrated approach of new medical curricula. The first section covers the basic principles, and the rest is organised by body systems. The book ends with sections on toxicity and prescribing practice. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Kinetics chapter simplified with more practical examples Includes more on genetic issues Drug tables made more concise to make information more accessible Fully updated to reflect current clinical practice

Download or read book Vascular Medicine A Companion to Braunwald s Heart Disease E Book written by Mark Creager and published by Elsevier Health Sciences. This book was released on 2019-05-22 with total page 963 pages. Available in PDF, EPUB and Kindle. Book excerpt: With authoritative coverage of everything from recent discoveries in the field of vascular biology to recent clinical trials and evidence-based treatment strategies, Vascular Medicine, 3rd Edition, is your go-to resource for improving your patients' cardiovascular health. Part of the Braunwald family of renowned cardiology references, this updated volume integrates a contemporary understanding of vascular biology with a thorough review of clinical vascular diseases, making it an ideal reference for vascular medicine specialists, general cardiologists, interventional cardiologists, vascular surgeons, and interventional radiologists. - Incorporates technologic advances in vascular imaging – including ultrasound, MRI, CTA, and catheter-based angiography – along with more than 230 new figures, providing an up-to-date and complete view of the vascular system and vascular diseases. - Covers novel antithrombotic therapies for peripheral artery disease and venous thromboemboism, advances in endovascular interventions for aortic aneurysms, and today's best surgical treatments for vascular diseases. - Includes seven new chapters: Pathobiology of Aortic Aneurysms; Pathobiology and Assessment of Cardiovascular Fibrosis; Large Vessel Vasculitis; Medium and Small Vessel Vasculitis; Epidemiology and Prognosis of Venous Thromboembolic Disease; Fibromuscular Dysplasia; and Dermatologic Manifestations of Vascular Disease. - Discusses methods for aggressive patient management and disease prevention to ensure minimal risk of further cardiovascular problems. - Keeps you current with ACC/AHA and ECC guidelines and the best ways to implement them in clinical practice. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices

Download or read book The Prostaglandins written by Peter Ramwell and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is much evidence to suggest that prostaglandins may have a physiological role to play in the control of thyroid gland metabolism, although the precise nature of this role remains to be defined. Prostaglandins have been found in normal thyroid tissue, and there is evidence of increased levels in some, but not all, cases of medullary carcinoma of the thyroid. which may account for the associated diarrhea. Exogenous prostaglandins, like TSH, bind to thyroid plasma mem branes, stimulate the adenylate cyclase-cyclic AMP system, thyroid hormone secretion, iodide organification, colloid droplet formation, glucose oxidation, and 32p incorporation into phospholipids. Prosta glandins of the E series are the most potent, although their maximal effects are generally less than the maximal effects of TSH. The interrelationships existing between TSH and prostaglandins have been the subject of intensive investigation, but as yet no one uni fying concept has emerged. TSH and prostaglandins have been shown to occupy different receptors on the thyroid plasma membrane. Al though TSH can increase intracellular prostaglandin levels, probably as a result of increased synthesis, prostaglandins do not appear to be essential intermediates in TSH action on adenylate cyclase. The pos sibility that prostaglandins are part of a negative feedback system con trolling TSH action is, as yet, a tentative hypothesis, and further work will be required to unravel the interrelationships between these sub stances that now appear to be far more complex than has been envisaged thus far.

Download or read book Smith s Anesthesia for Infants and Children E Book written by Peter J. Davis and published by Elsevier Health Sciences. This book was released on 2016-10-15 with total page 1829 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now thoroughly up to date with new chapters, Smith’s Anesthesia for Infants and Children, 9th Edition, by Drs. Peter Davis and Franklyn Cladis, covers the information you need to provide effective perioperative care for any type of pediatric surgery. Leading experts in pediatric anesthesia bring you up to date with every aspect of both basic science and clinical practice, helping you incorporate the latest clinical guidelines and innovations in your practice. Quick-reference appendices: drug dosages, growth curves, normal values for pulmonary function tests, and a listing of common and uncommon syndromes. Outstanding visual guidance in full color throughout the book. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. More than 100 video demonstrations, including new regional anesthesia videos, echocardiograms of congenital heart lesions, anatomic dissections of various congenital heart specimens with audio explanations, various pediatric surgical operative procedures, airway management, and much more. Table of Contents has been reorganized and new chapters added on statistics, sedation, pediatric obesity, and cardiac critical care pediatrics. A new chapter on regional anesthesia for pediatrics, including video and ultrasound demonstrations online. A new chapter on dermatology, specifically for the anesthesiologist, with more than 100 photos. A new chapter on medical missions to third-world countries, including what you should know before you go. A new Questions chapter provides opportunities for self-assessment. New coverage includes cardiac anesthesia for congenital heart disease, anesthesia outside the operating room, and a new neonatology primer for the pediatric anesthesiologist.

Download or read book Pharmacology in Anesthesia Practice written by Anita Gupta and published by Oxford University Press. This book was released on 2013-04-25 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: The grasp of pharmacologic principles and their practical application sits at the heart of anesthesiology practice. Intended to fill the niche for a rapid, point-of-care overview of clinical pharmacology in anesthesia, this compact guide covers the commonly prescribed medications in anesthesiology including the subspecialties of obstetric, regional, cardiac, and neuroanesthesia.

Download or read book Angiogenesis in Health Disease and Malignancy written by Ali Salajegheh and published by Springer. This book was released on 2016-03-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about “Angiogenesis”. A process in which new vasculature is formed from pre-existing capillaries. Angiogenesis process is associated with the proliferation and growth of both physiologically normal and neoplastic tissues, through the formation of vascular supply, essential for delivering growth requirements such as oxygen and nutrients. The book describes more than 100 genes and their key regulatory functions in the context of normal healthy condition, disease and malignancy, cancer proliferation and progression. New insights into the role of angiogenesis and the therapeutic inhibition of its regulators are investigated, due to the great potential for exploitation in the development of a novel treatment for cancer. New scientists, junior researchers and biomedical science students will find this book an invaluable introductory reference to their insight about angiogenesis and angiogenic role of more than 100 angiogenes and their role in healthy, disease and malignant conditions.

Download or read book The Prostaglandins written by M. F. Cuthbert and published by Elsevier. This book was released on 2016-01-26 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Prostaglandins: Pharmacological and Therapeutic Advances provides a concise account of the more important theoretical developments and areas in which the prostaglandins are being introduced into clinical practice or have potential clinical application. Chapters I to IV of this book deal with the chemistry and classification, distribution and metabolism, general pharmacology, and mechanism of action. The rest of the chapters discuss the relationship of the prostaglandins to the reproductive, cardiovascular, respiratory, and gastro-intestinal systems with an emphasis on the human pharmacology and potential therapeutic applications. This text also includes the speculations and suggestions of contributors regarding the possible and further use of the prostaglandins. This publication is a good reference for biochemists and medical students concerned with the potential of prostaglandins.

Download or read book Robinson s Current Therapy in Equine Medicine written by Kim A. Sprayberry and published by Elsevier Health Sciences. This book was released on 2014-05-01 with total page 1035 pages. Available in PDF, EPUB and Kindle. Book excerpt: - ALL-NEW topics provide updates on infectious diseases, including herpesvirus, equine granulocytic anaplasmosis, and lawsonia infection and proliferative enteropathy; pain diagnosis and multimodal management; management of thoracic and airway trauma, imaging, endoscopy, and other diagnostic procedures for the acute abdomen; and neurologic injury. - 212 concise, NEW chapters include both a succinct guide to diagnosis of disorders and a detailed discussion of therapy. - NEW images demonstrate advances in various imaging techniques. - Thoroughly updated drug appendices, including all-new coverage of drug dosages for donkeys and mules, provide a handy, quick reference for the clinical setting.

Download or read book The Prostaglandins written by Sultan M.M. Karim and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: The voluminous literature on prostaglandins includes some excellent reviews. For some time however, there has been a need for the collection in one volume of information from individual experts actively engaged in different aspects of prostaglandin research. This book is an attempt to fulfil that need. In view of the expanding interest and ever-growing accumulation of data of the various effects of prostaglandins it is hoped to revise the book and bring it up-to-date periodically. The largest section is that on reproduction, in which field progress in research and clinical applications thereof have been, and are, of great significance particularly in the area of popula tion control. This is not to decry the skill and efforts of investi gators in other aspects of prostaglandin activity nor the potential biological or therapeutic importance of their findings. In this context, what may appear to be omissions are individual sections on prostaglandin activity in the central nervous system, in the eye and as mediators of the inflammatory response. These are considered in the chapter on General Pharmacology of the Prostaglandins not because they might be considered to be of lesser impact and significance but in order to achieve a rapid publication of the book. S. M. M. KARIM Kampala, Uganda. January 1972. Acknowledgements Tables and Figures previously published are, in general, acknowledged by the reference in the legends and I am grateful to the authors, editors and publishers for their per mission.

Download or read book The Prostaglandin System written by F. Berti and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostaglandin research is one of the most explosive fields in the biological science, and there have been a number of international symposia on this subject. In planning the second Advanced Course in Erice (Sicily) at the "Ettore Majorana" center it was realized that large congresses might not represent the best way to facilitate communication within specialized areas of biologic and medical research. In fact small meetings where in depth discussion is confined to a limited number of scientists, are now generally considered successful vehicles of scientific information. With this in mind, we made an effort in collecting a number of experts in both experimental and clinical use of these important arachidonate metabolites. We have been very fortunate in bringing together a faculty of international authorities who contributed to the course with brilliant presentations and lively discussion. Thus, this book represents an up-to-date overview of the physiology and pharmacology of different products derived from arachidonic acid metabolism, associated with outstanding suggestions of their clinical potential. It is our hope that from this Advanced Course, and its resulting publication, new ideas concerning the physio pathological role of these compounds will arise together with new directions for future research. We are deeply indebted to NATO for its interest and generous support which made this Second Course a reality.

Download or read book Effects of Lifestyle on Men s Health written by Faysal A. Yafi and published by Academic Press. This book was released on 2019-08-21 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Effects of Lifestyle on Men's Health provides an evidence-based review of the effects of modifiable risk factors such as sleep, diet, stress and exercise on various elements of men's health, notably sexual function, urinary function and cancer prevention and detection. Content highlights the most up-to-date basic and clinical information available, along with future research directions. Each chapter provides an easy to reference bullet point style summary to highlight the salient take-home messages from each section. Researchers and clinicians alike can use this book as a reference point for all matters related to lifestyle and men's health. - Offers an evidence-based review of the associations between modifiable risk factors (diet, lifestyle, sleep, environment and exercise) and men's health - Delivers examples of how changes to risk factors improve overall health - Provides insight into what the future of men's health holds in terms of basic and clinical research

Download or read book Comprehensive Vascular and Endovascular Surgery written by John W. Hallett Jr. and published by Elsevier Health Sciences. This book was released on 2009-09-30 with total page 934 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Vascular and Endovascular Surgery, 2nd Edition, edited by John W. Hallett, Jr., MD, FACS, Joseph L. Mills, MD, Jonothan Earnshaw, DM, FRCS, Jim A. Reekers, MD, PhD, and Thom Rooke, MD delivers in-depth, clinically focused coverage of all aspects of vascular surgery in an exceptionally well-designed single reference. Each disease chapter follows the same consistent format, for quick consultation and better comprehension. The revised 2nd Edition features several new chapters, increased endovascular treatment coverage, and updated data from the latest trials...bringing you the newest advances from the field. More than 1,000 photographs, line drawings and tables-including many revised illustrations now in color-depict key concepts and procedures. With its practical user friendly approach-and online access through Expert Consult functionality-this resource offers convenient access to complete guidance. Presents the work of a team of nearly 80 internationally respected vascular surgeons and interventional radiologists who focus on the issues and challenges you face in everyday practice. Uses a highly structured, templated format in each chapter to quickly and consistently deliver information on basic science, clinical presentation, non-invasive testing, medical management, surgical management, complications, outcome, and follow up-making information easy to access and understand. Includes Key Points boxes in every chapter that allow for quick reference and efficient study. Features over 1,000 photographs, line drawings, charts and tables that make important information easy to comprehend. Integrates clinical information with basic science making the material relevant to everyday practice. Covers treatment and interventions from an evidence-based perspective, whenever possible. Provides short, clinical vignettes in the same style as those found on oral exams. Provides online access to the text via expertconsult.com where you can perform quick searches of the complete contents, download all of the images, further your study with bonus review and self assessment questions, and follow links to PubMed abstracts for convenient consultation whwere and when you need it most. Offers new chapters on vascular diagnosis, graft infections, aortic dissection, and visceral aneurysms for greater coverage of the field. Includes a significant increase in endovascular treatment coverage in many of the chapters, reflecting the growing need for experience in these procedures. Presents current data from DREAM and EVAR 1 and 2 trials. Features a revised artwork program-including many revised illustrations and former black and white images now in color-for an enhanced visual understanding of concepts. Includes bonus review and self assessment questions accompany the online version.

Download or read book WHO Recommendations written by World Health Organization and published by . This book was released on 2018 with total page 43 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary goal of this guideline is to provide a foundation for the implementation of interventions shown to have been effective in reducing the burden of PPH (postpartum haemorrhage). Health professionals responsible for developing national and local health policies constitute the main target audience of this document. Obstetricians, midwives, general medical practitioners, health care managers and public health policy-makers, particularly in under-resourced settings are also targeted. This document establishes general principles of PPH care and it is intended to inform the development of clinical protocols and health policies related to PPH.

Download or read book Critical Heart Disease in Infants and Children E Book written by Ross M. Ungerleider and published by Elsevier Health Sciences. This book was released on 2018-09-26 with total page 1195 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Selected for Doody's Core Titles® 2024 with "Essential Purchase" designation in Pediatric Surgery** Now in brilliant full color and reflecting recent significant changes in the field, Critical Heart Disease in Infants and Children, 3rd Edition, keeps you abreast of the skills and knowledge required to safely care for children with congenital and acquired heart disease in the ICU. Pediatric intensivists, cardiologists, cardiac surgeons, and anesthesiologists from leading centers around the world provide a well-rounded perspective on basic scientific principles, medical and pharmacologic treatments, surgical techniques, and equipment. - Features comprehensive updates throughout the text, including indications, techniques, potential complications in perioperative management of patients, and surgical techniques for congenital heart disease. - Covers recent advances in the treatment of pulmonary hypertension, developments in mechanical assist devices, heart and lung transplantation, and interventional cardiac catheterization. - Features an all-new, full-color format that speeds navigation and helps clarify complex concepts. - Contains 27 new chapters with an emphasis on the team approach to patient care in the ICU including creating multidisciplinary teams, quality and performance improvement, training , and challenges and solutions to developing a cohesive team environment. - Includes a detailed chapter on bedside ultrasound, walking you through the techniques you're most likely to encounter in the ICU. - Employs well-documented tables, text boxes, and algorithms to make clinical information easy to access, and more than two dozen video clips provide a more complete understanding of echocardiography, imaging modalities, pulmonary hypertension, and more. - Describes the basic pharmacology and clinical applications of new pharmacologic agents. - Examines issues affecting adults with congenital heart disease. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. - Offers four completely new chapters: Cardiac Trauma, Congenital Heart Disease in the Adult, Congenitally Corrected Transposition of the Great Arteries, and Outcome Evaluation. - Describes the basic pharmacology and clinical applications of all of the new pharmacologic agents. - Details important refinements and developments in surgical techniques, including the Ross pulmonary autograft replacement of the aortic valve, video-assisted fluoroscopy, and the extracardiac Fontan connection, and discusses their indications and potential complications. - Explores the latest advances in the treatment of pulmonary hypertension, new developments in mechanical assist devices, heart and lung transplantation, and interventional cardiac catheterization. - Examines issues affecting adults with congenital heart disease.

Download or read book Meyler s Side Effects of Endocrine and Metabolic Drugs written by Jeffrey K. Aronson and published by Elsevier. This book was released on 2009-02-21 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: Elsevier now offers a series of derivative works based on the acclaimed Meylers Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing physician or health care clinician. Endocrine and metabolic diseases are common, includes diseases such as diabetes, thyroid disease, and obesity. Endocrinologists, including diabetes professionals, internal medicine and primary care practitioners, obstetricians and gynecologists, and others will find this book useful when treating endocrine or metabolic diseases.The material is drawn from the 15th edition of the internationally renowned encyclopedia, Meyler's Side Effects of Drugs, and the latest volumes in the companion series, Side Effects of Drugs Annuals. Drug names have usually been designated by their recommended or proposed International Non-proprietary Names (rINN or pINN); when those are not available, clinical names have been used. In some cases, brand names have been used.This volume is critical for any health professional involved in the administration of endocrine and metabolics mediations. - - Surpasses the Physician's Desk Reference © by including clinical case studies and independent expert analysis - Complete index of drug names - Most complete cross referencing of drug-drug interactions available - Extensive references to primary and secondary literature - Also includes information on adverse effects in pregnancy The book is divided into eight sections: - Corticosteroids and related drugs - Prostaglandins - Sex hormones and related drugs - Iodine and drugs that affect thyroid function - Insulin and other hypoglycemic drugs - Other hormones and related drugs - Lipid-regulated drugs - Endocrine and metabolic adverse effects of non-hormonal and non-metabolic drugs

Download or read book Visual Guide to Neonatal Cardiology written by Ernerio T. Alboliras and published by John Wiley & Sons. This book was released on 2018-04-30 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Visual Guide to Neonatal Cardiology is a comprehensive, highly illustrated, reference covering the evaluation, diagnosis and management of cardiac disease in the newborn. Contains over 900 color illustrations, including patient photographs, chest roentgenograms, electrocardiograms, echocardiograms, angiocardiograms, 3D computed tomogramphy, magnetic resonance imaging, pathologic specimens, and other relevant visual aids Discusses the natural history of fetal heart disease and the rationale, indications, technique, and impact of fetal cardiac intervention Reviews the anatomy and physiology of the neonatal cardiovascular system, including differences within the fetal, transitional, neonatal, child and adult circulatory system Highlights key steps for taking a patient history, including detailed discussion of the cardiac examination (inspection, palpation and auscultation of heart sounds and murmurs) Presents over 35 morphologic conditions with sections covering introduction, epidemiology, etiology with accepted or postulated embryogenesis, pathophysiology, clinical presentation, physical examination findings, diagnostic evaluation, management, and prognosis Includes a neonatal formulary reviewing selected medications currently used for treatment of perioperative low cardiac output, congestive heart failure, pulmonary hypertension, sedation, pain and anticoagulation in neonates