Download or read book Total Synthesis of Maoecrystal V written by Jianxian Gong and published by Springer. This book was released on 2014-07-08 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this thesis, the author describes the total synthesis of natural product Maoecrystal V in detail. In the first part of the thesis, the author introduces the research background and reviews the research progress in total synthesis of Maoecrystal V. In the second part, the author develops a novel and concise approach for the stereo selective construction of the tetracyclic model system of Maoecrystal V. The model system is accomplished in 8 steps with 20% yield. In the third part, the author describes the first successful total synthesis of Maoecrystal V and investigates four strategies for constructing the key tetrahydrofuran oxa-bridge skeleton. The total synthesis starts from a known compound and is accomplished in 17 steps with 1.2% yield. The successful total synthesis of Maoecrystal V will contribute to the development of efficient synthetic strategies for natural products and other compounds with complex structures.

Download or read book Argonne List of Serials written by Argonne National Laboratory. Library Services Department and published by . This book was released on 1972 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Introduction to Strategies for Organic Synthesis written by Laurie S. Starkey and published by John Wiley & Sons. This book was released on 2018-05-01 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the Gap Between Organic Chemistry Fundamentals and Advanced Synthesis Problems Introduction to Strategies of Organic Synthesis bridges the knowledge gap between sophomore-level organic chemistry and senior-level or graduate-level synthesis to help students more easily adjust to a synthetic chemistry mindset. Beginning with a thorough review of reagents, functional groups, and their reactions, this book prepares students to progress into advanced synthetic strategies. Major reactions are presented from a mechanistic perspective and then again from a synthetic chemist’s point of view to help students shift their thought patterns and teach them how to imagine the series of reactions needed to reach a desired target molecule. Success in organic synthesis requires not only familiarity with common reagents and functional group interconversions, but also a deep understanding of functional group behavior and reactivity. This book provides clear explanations of such reactivities and explicitly teaches students how to make logical disconnections of a target molecule. This new Second Edition of Introduction to Strategies for Organic Synthesis: Reviews fundamental organic chemistry concepts including functional group transformations, reagents, stereochemistry, and mechanisms Explores advanced topics including protective groups, synthetic equivalents, and transition-metal mediated coupling reactions Helps students envision forward reactions and backwards disconnections as a matter of routine Gives students confidence in performing retrosynthetic analyses of target molecules Includes fully-worked examples, literature-based problems, and over 450 chapter problems with detailed solutions Provides clear explanations in easy-to-follow, student-friendly language Focuses on the strategies of organic synthesis rather than a catalogue of reactions and modern reagents The prospect of organic synthesis can be daunting at the outset, but this book serves as a useful stepping stone to refresh existing knowledge of organic chemistry while introducing the general strategies of synthesis. Useful as both a textbook and a bench reference, this text provides value to graduate and advanced undergraduate students alike.

Download or read book Progress in the Chemistry of Organic Natural Products 115 written by A. Douglas Kinghorn and published by Springer Nature. This book was released on 2021-04-02 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.

Download or read book Total Synthesis of Natural Products written by Jie Jack Li and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.

Download or read book Classics in Total Synthesis written by K. C. Nicolaou and published by John Wiley & Sons. This book was released on 1996-04-11 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt: K.C. Nicolaou - Winner of the Nemitsas Prize 2014 in Chemistry This book is a must for every synthetic chemist. With didactic skill and clarity, K. C. Nicolaou and E. Sorensen present the most remarkable and ingenious total syntheses from outstanding synthetic organic chemists. To make the complex strategies more accessible, especially to the novice, each total synthesis is analyzed retrosynthetically. The authors then carefully explain each synthetic step and give hints on alternative methods and potential pitfalls. Numerous references to useful reviews and the original literature make this book an indispensable source of further information. Special emphasis is placed on the skillful use of graphics and schemes: Retrosynthetic analyses, reaction sequences, and stereochemically crucial steps are presented in boxed sections within the text. For easy reference, key intermediates are also shown in the margins. Graduate students and researchers alike will find this book a gold mine of useful information essential for their daily work. Every synthetic organic chemist will want to have a copy on his or her desk.

Download or read book New Serial Titles written by and published by . This book was released on 1989 with total page 1944 pages. Available in PDF, EPUB and Kindle. Book excerpt: A union list of serials commencing publication after Dec. 31, 1949.

Download or read book Fortschritte der Chemie Organischer Naturstoffe Progress in the Chemistry of Organic Natural Products Progr s dans la Chimie des Substances Organiques Naturelles written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Advances in Organic Synthesis written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2018-08-01 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field. This volume presents the following reviews: • Asymmetric hydrogenation of tetrasubstituted olefins • Recent advances in catalytic organic synthesis applications of covalently supported ionic liquids • Recent developments in intramolecular cyclization reactions via carbon-heteroatom (c-x) bond formation • Efficient synthetic protocol and mechanistic study of quinazoline analogues and their biological importance • Synthesis of N,O,S-heterocycles by one-pot reactions of epoxides, aziridines and oxaziridines

Download or read book Advances in Lipid Research written by Rodolfo Paoletti and published by Elsevier. This book was released on 2014-11-25 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Lipid Research, Volume 3 presents the analysis of human serum lipoproteins and emphasizes the possibilities inherent in the application of computer methods to such analyses. This book discusses the effects of various drugs on the other important component of the serum lipids, the phospholipids. Organized into six chapters, this volume begins with an overview of the possibility of a dehydrogenation toward the methyl group. This text then presents a detailed discussion of lipoprotein structure, metabolism, and catabolism. Other chapters consider some potentially significant revisions in lipoprotein procedure, including additions to the technology of lipoprotein analysis. This book discusses as well the chemistry and metabolism of plasma lipoprotein as related to physiological and disease states. The final chapter deals with the advances in methods of purification and studies of the properties and mode of action of lipases. This book is a valuable resource for organic chemists, neurochemists, and biochemists.

Download or read book Advances in Organometallic Chemistry written by Pedro J. Perez and published by Academic Press. This book was released on 2021-06-17 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Organometallic Chemistry, Volume 76, the latest release in this longstanding serial is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more. It is ideal for a wide range of researchers involved in organometallic chemistry, including synthetic protocols, mechanistic studies and practical applications. - Contains contributions from leading authorities in the field of organometallic chemistry - Covers topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more - Informs and updates readers on the latest developments in the field - Carefully edited to provide easy-to-read material

Download or read book Recent Advances in Synthesizing and Utilizing Nitrogen containing Heterocycles written by Hyun-Joon Ha and published by Frontiers Media SA. This book was released on 2024-05-31 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitrogen-containing heterocycles, so-called aza-heterocycles, are widely found in natural products, pharmaceuticals, agrochemicals, and functional materials, and thus their synthesis has long been studied intensively. In addition, their preparation and utilization as synthons or intermediates from one to another are also developed to build higher and more complex aza-heterocycles. Some of them are also used as ligands for metal catalysts and organocatalysts. Despite many studies of the synthesis and utilization of nitrogen-containing heterocycles, a more efficient and general preparation is still required to diversify the structural backbones and improve their biological activities. Their usage as ligands and catalysts is also under expansion in various reactions.

Download or read book Advances in Transition Metal Mediated Heterocyclic Synthesis written by Daniel Sole and published by Academic Press. This book was released on 2018-05-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Transition-Metal Mediated Heterocyclic Synthesis provides an overview of recent catalytic reactions involving transition metals to produce heterocyclic compounds. The book is organized according to the type of transformation used to achieve the synthesis of the heterocyclic systems (mainly aza- and oxa-heterocycles). As such, it covers recent applications on the synthesis of heterocycles, also describing the details of the novel transformations in a didactic manner to motivate readers in search of new catalytic processes. The editors have included state-of-the-art strategies, including transition-metal reactions involving unsaturated systems (reactions of allenes, new gold(I)-catalyzed reactions, and Prins reaction). Chapters highlight the versatility of organopalladium chemistry dealing with carbonylative transformations, C-H activation reactions, coupling processes, and the control of the ambiphilic character of organopalladium species. Finally, the book discusses new reactions leading to heterocycles based on C-H activation processes catalyzed by other metals (Rh, Ru, Co). Written by an outstanding team of authors who are leading experts in organometallic chemistry and organic synthesis, this book is a valuable resource not only for chemists mainly focused on synthesis, but also for those interested in reaction mechanisms involving transition metals. - Helpfully organized by transformation type to stimulate the search for new synthetic processes - Completely illustrated and written by global experts - Includes thoughtfully selected strategies chosen by the editors to exemplify the state-of-the-art of the subject, including transition-metal reactions involving unsaturated systems, organopalladium chemistry, and metal-catalyzed C-H activation

Download or read book Advances in Carbohydrate Chemistry and Biochemistry written by and published by Elsevier. This book was released on 2003-12-17 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its inception in 1945, Advances in Carbohydrate Chemistry and Biochemistry has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry. - High quality comprehensive reviews covering all aspects of carbohydrate chemistry

Download or read book Progress in Heterocyclic Chemistry written by Gordon Gribble and published by Elsevier. This book was released on 2011-09-22 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Heterocyclic Chemistry (PHC) is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year's literature on heterocyclic chemistry and articles on emerging topics of particular interest to heterocyclic chemists. The chapters in Volume 23 constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2010. As with previous volumes in the series, Volume 23 apprises academic/industrial chemists and advanced students of developments in heterocyclic chemistry in a convenient format. - Covers the heterocyclic literature published in 2010 - Includes specialized reviews - Features contributions from leading researchers in their fields

Download or read book Advances in Organic Synthesis Volume 13 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2020-11-03 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field. This volume presents the following reviews: Electroluminescent polymers - a review on synthesis from organic compounds Remarkable advances in the asymmetric synthesis of biologically active natural compounds from the advent of chiral auxiliaries The chemistry of ynamides and their application in organic synthesis Carbon-heteroatom bond formation for medium ring heterocycles Tin(ii) salts: versatile and efficient lewis acid catalysts in reactions to add value to the glycerol and terpenic alcohols (E)-n-methyl-1-(methylthio)-2-nitroethenamine (nmsm) as a versatile ambiphilic synthon in organic synthesis.

Download or read book Recent Developments Of Diazo Compounds In Organic Synthesis written by Di Qiu and published by World Scientific. This book was released on 2020-12-29 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diazo compounds are versatile substances with diverse transformations in organic synthesis and other fields. Studies of diazo compounds have been ongoing for a very long time but still attract significant attention within the organic chemistry community, with new papers related to diazo compounds appearing at a daily pace. Over the past twenty years, there have been over fifty reviews and accounts related to the reactions of diazo compounds, but most of them cover limited aspects of diazo compounds. In addition to organic synthesis, diazo compounds have found applications in interdisciplinary fields such as material sciences, chemical biology and also polymerization.In this comprehensive book, the authors cover the most recent advances in the fields related to diazo compounds, including the application of donor-acceptor carbenes, carbene-based cross-coupling reactions and polymerizations, as well as the breakthrough in catalytic asymmetric carbene O-H, S-H, and N-H bond insertions. They also cover the application of flow chemistry in diazo reactions. The authors aim to provide a contemporary and comprehensive review for investigators engaged in or with interest in diazo compounds to boost further developments in this fascinating field.