Download or read book Production of Biomass and Bioactive Compounds Using Bioreactor Technology written by Kee-Yoeup Paek and published by Springer. This book was released on 2014-09-30 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bioactive compounds of plants have world-wide applications in pharmaceutical, nutraceutical and food industry with a huge market. In this book, a group of active researchers have addressed on the most recent advances in plant cell and organ cultures for the production of biomass and bioactive compounds using bioreactors. Tremendous efforts have been made to commercialize the production of plant metabolites by employing plant cell and organ cultures in bioreactors. This book emphasizes on the fundamental topics like designing of bioreactors for plant cell and organ cultures, various types of bioreactors including stirred tank, airlift, photo-bioreactor, disposable bioreactor used for plant cell and organ cultures and the advantages and disadvantages of bioreactor cultures. Various strategies for biomass production and metabolite accumulation have been discussed in different plant systems including Korean/Chinese ginseng, Siberian ginseng, Indian ginseng, Echinacea, St. John’s wort, Noni, Chinese licorice, Caterpillar fungus and microalgae. Researches on the industrial application of plant cells and organs with future prospects as well as the biosafety of biomass produced in bioreactors are also described. The topics covered in this book, such as plant cell and organ cultures, hairy roots, bioreactors, bioprocess techniques, will be a valuable reference for plant biotechnologists, plant biologists, pharmacologists, pharmacists, food technologists, nutritionists, research investigators of healthcare industry, academia, faculty and students of biology and biomedical sciences. The multiple examples of large-scale applications of cell and organ cultures will be useful and significant to industrial transformation and real commercialization.

Download or read book Biorefinery Production Technologies for Chemicals and Energy written by Arindam Kuila and published by John Wiley & Sons. This book was released on 2020-10-21 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers almost all of the diverse aspects of utilizing lignocellulosic biomass for valuable biorefinery product development of chemicals, alternative fuels and energy. The world has shifted towards sustainable development for the generation of energy and industrially valuable chemicals. Biorefinery plays an important role in the integration of conversion process with high-end equipment facilities for the generation of energy, fuels and chemicals. The book is divided into four parts. The first part, "Basic Principles of Biorefinery," covers the concept of biorefinery, its application in industrial bioprocessing, the utilization of biomass for biorefinery application, and its future prospects and economic performance. The second part, "Biorefinery for Production of Chemicals," covers the production of bioactive compounds, gallic acid, C4, C5, and C6 compounds, etc., from a variety of substrates. The third part, "Biorefinery for Production of Alternative Fuel and Energy," covers sustainable production of bioethanol, biodiesel, and biogas from different types of substrates. The last part of this book discusses sequential utilization of wheat straw, material balance, and biorefinery approach. The approaches presented in this book will help readers/users from different areas like process engineering and biochemistry to plan integrated and inventive methods to trim down the expenditure of the industrial manufacture process to accomplish cost-effective feasible products in biorefinery.

Download or read book Food Toxicology written by Debasis Bagchi and published by CRC Press. This book was released on 2016-11-25 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food toxicology studies how natural or synthetic poisons and toxicants in diverse food products cause harmful, detrimental, or adverse side effects in living organisms. Food toxicology is an important consideration as food supply chain is becoming more multinational in origin, and any contamination or toxic manifestation may cause serious, wide-spread adverse health effects. Food Toxicology covers various aspects of food safety and toxicology, including the study of the nature, properties, effects, and detection of toxic substances in food and their disease manifestations in humans. It will also include other aspects of consumer product safety. The first two chapters discuss the measurement of toxicants and toxicity and the importance of dose-response in food toxicology. Additional chapters discuss the aspects of food associated carcinogenesis and food-derived chemical carcinogenesis, food allergy, pathogens associated with fruits and vegetables, and the detrimental effects of radionuclides exposure. The chapters also cover the most important heavy metal contaminants, namely mercury, lead and vanadium, and Fluoride toxicity, which is extensively discussed in its own chapter. Toxicologists, scientists, researchers in food toxicology, nutritionists, and public health care professionals will find valuable information in this book on all possible intricate areas of food toxicology.

Download or read book Disposable Bioreactors II written by Dieter Eibl and published by Springer. This book was released on 2013-12-17 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dynamic Single-Use Bioreactors Used in Modern Liter- and m3- Scale Biotechnological Processes: Engineering Characteristics and Scaling Up, by Christian Löffelholz, Stephan C. Kaiser, Matthias Kraume, Regine Eibl , Dieter Eibl. Orbitally Shaken Single-Use Bioreactors, by Wolf Klöckner, Sylvia Diederichs, Jochen Büchs. Therapeutic Human Cells: Manufacture for Cell Therapy/Regenerative Medicine by Christian van den Bos, Robert Keefe, Carmen Schirmaier, Michael McCaman. Fast Single-Use VLP Vaccine Productions Based on Insect Cells and the Baculovirus Expression Vector System: Influenza as Case Study by Regine Eibl, Nina Steiger, Sabine Wellnitz, Tiago Vicente, Corinne John, Dieter Eibl. Microbial High Cell Density Fermentations in a Stirred Single-Use Bioreactor by Thomas Dreher, Bart Walcarius, Ute Husemann, Franziska Klingenberg, Christian Zahnow, Thorsten Adams, Davy de Wilde, Peter Casteels, Gerhard Greller. Quorus Bioreactor: A New Perfusion-Based Technology for Microbial Cultivation by Sheena J. Fraser, Christian Endres. Cultivation of Marine Microorganisms in Single-Use Systems by Friederike Hillig, Maciej Pilarek, Stefan Junne, Peter Neubauer. Flexible Biomanufacturing Processes that Address the Needs of the Future by Bernhard Diel, Christian Manzke, Thorsten Peuker. An Approach to Quality and Security of Supply for Single-Use Bioreactors by Magali Barbaroux, Susanne Gerighausen, Heiko Hackel. A Risk Analysis for Production Processes with Disposable Bioreactors by Tobias Merseburger, Ina Pahl, Daniel Müller, Markus Tanner.

Download or read book Biorefinery Co Products written by Chantal Bergeron and published by John Wiley & Sons. This book was released on 2012-02-21 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to successfully compete as a sustainable energy source, the value of biomass must be maximized through the production of valuable co-products in the biorefinery. Specialty chemicals and other biobased products can be extracted from biomass prior to or after the conversion process, thus increasing the overall profitability and sustainability of the biorefinery. Biorefinery Co-Products highlights various co-products that are present in biomass prior to and after processing, describes strategies for their extraction , and presents examples of bioenergy feedstocks that contain high value products. Topics covered include: Bioactive compounds from woody biomass Phytochemicals from sugar cane, citrus waste and algae Valuable products from corn and other oil seed crops Proteins from forages Enhancing the value of existing biomass processing streams Aimed at academic researchers, professionals and specialists in the bioenergy industry, Biorefinery Co-Products is an essential text for all scientists and engineers working on the efficient separation, purification and manufacture of value-added biorefinery co-products. For more information on the Wiley Series in Renewable resources, visit www.wiley.com/go/rrs

Download or read book Plant Food Phytochemicals and Bioactive Compounds in Nutrition and Health written by John Oloche Onuh and published by CRC Press. This book was released on 2024-02-27 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemicals are receiving increasing attention due to their observed nutritional and health-promoting effects in numerous food applications. As plant secondary metabolites with bioactive properties, they may provide desirable health benefits beyond basic nutrition to reduce chronic disease conditions. Their importance in nutrition and health cannot be overstated as it has generated so much interest and studies focused on elucidating their roles has produced so many outstanding results. Plant phytochemicals are readily used in alternative medicine in South East Asia especially, in China and India and they are becoming widely acceptable worldwide. However, very little is still known about the phytochemicals despite these intense research efforts because of their diverse biological and chemical nature. In this newest addition to the series, Nutraceuticals: Basic Research and Clinical Applications, Plant Food Phytochemicals and Bioactive Compounds in Nutrition and Health provides a comprehensive review of the current state of knowledge in the field of bioactive plant phytochemical compounds, their food sources, bioactivities, bioavailability, extraction, production, and applications. Experts in the field discuss various bioactivities of the notable and promising plant phytochemicals of significance in nutrition and health, e.g., lowering of CVD, hypertension, cholesterol, diabetes, obesity, inflammation, cancer, oxidative stress, neurodegenerative diseases and a host of other chronic disease conditions. Key Features: Describes the various nutritional and bioactive significances of notable and promising plant phytochemicals of significance in nutritional and medical research and their food and/or plant sources Includes various approaches for the quantification, extraction and production of the notable and promising phytochemical compounds in nutrition and health Examines the challenges and promises of plant phytochemical as ingredients for the development of functional foods and nutraceuticals as well as their use in alternative medicine Discusses regulatory issues regarding plant phytochemicals, especially as it pertains to their health claims and use

Download or read book Bioprocessing for Biomolecules Production written by Gustavo Molina and published by John Wiley & Sons. This book was released on 2020-01-21 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the many recent innovations and advancements in the field of biotechnological processes This book tackles the challenges and potential of biotechnological processes for the production of new industrial ingredients, bioactive compounds, biopolymers, energy sources, and compounds with commercial/industrial and economic interest by performing an interface between the developments achieved in the recent worldwide research and its many challenges to the upscale process until the adoption of commercial as well as industrial scale. Bioprocessing for Biomolecules Production examines the current status of the use and limitation of biotechnology in different industrial sectors, prospects for development combined with advances in technology and investment, and intellectual and technical production around worldwide research. It also covers new regulatory bodies, laws and regulations, and more. Chapters look at biological and biotechnological processes in the food, pharmaceutical, and biofuel industries; research and production of microbial PUFAs; organic acids and their potential for industry; second and third generation biofuels; the fermentative production of beta-glucan; and extremophiles for hydrolytic enzymes productions. The book also looks at bioethanol production from fruit and vegetable wastes; bioprocessing of cassava stem to bioethanol using soaking in aqueous ammonia pretreatment; bioprospecting of microbes for bio-hydrogen production; and more. Provides up to date information about the advancements made on the production of important biotechnological ingredients Complete visualization of the general developments of world research around diverse products and ingredients of technological, economic, commercial and social importance Investigates the use and recovery of agro-industrial wastes in biotechnological processes Includes the latest updates from regulatory bodies for commercialization feasibility Offering new products and techniques for the industrial development and diversification of commercial products, Bioprocessing for Biomolecules Production is an important book for graduate students, professionals, and researchers involved in food technology, biotechnology; microbiology, bioengineering, biochemistry, and enzymology.

Download or read book Single Use Technology in Biopharmaceutical Manufacture written by Regine Eibl and published by John Wiley & Sons. This book was released on 2019-07-18 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authoritative guide to the principles, characteristics, engineering aspects, economics, and applications of disposables in the manufacture of biopharmaceuticals The revised and updated second edition of Single-Use Technology in Biopharmaceutical Manufacture offers a comprehensive examination of the most-commonly used disposables in the manufacture of biopharmaceuticals. The authors—noted experts on the topic—provide the essential information on the principles, characteristics, engineering aspects, economics, and applications. This authoritative guide contains the basic knowledge and information about disposable equipment. The author also discusses biopharmaceuticals’ applications through the lens of case studies that clearly illustrate the role of manufacturing, quality assurance, and environmental influences. This updated second edition revises existing information with recent developments that have taken place since the first edition was published. The book also presents the latest advances in the field of single-use technology and explores topics including applying single-use devices for microorganisms, human mesenchymal stem cells, and T-cells. This important book: • Contains an updated and end-to-end view of the development and manufacturing of single-use biologics • Helps in the identification of appropriate disposables and relevant vendors • Offers illustrative case studies that examine manufacturing, quality assurance, and environmental influences • Includes updated coverage on cross-functional/transversal dependencies, significant improvements made by suppliers, and the successful application of the single-use technologies Written for biopharmaceutical manufacturers, process developers, and biological and chemical engineers, Single-Use Technology in Biopharmaceutical Manufacture, 2nd Edition provides the information needed for professionals to come to an easier decision for or against disposable alternatives and to choose the appropriate system.

Download or read book Biosynthesis of Bioactive Compounds in Medicinal and Aromatic Plants written by Nitish Kumar and published by Springer Nature. This book was released on 2023-09-12 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant bioactive compounds are plant-based natural products that display a variety of pharmacological applications. These bioactive compounds are important as medicines, pigments and flavorings since most of the pharmaceutical industries are highly dependent on medicinal plants and their extraction. The types and concentrations of bioactive compounds produced by plants are determined by the species, genotype, physiology, developmental stage and environmental factors during growth, determining the physiological adaptive responses employed by various plant taxonomic groups in coping with the stress and defensive stimuli. In the past two decades there has been a renewed interest in the study of conventional aspects such as elicitors and biotic and abiotic stress factors that influence secondary metabolism during in vitro and in vivo growth of plants. the application of molecular biology tools and techniques are facilitating increased understanding of the signaling processes and pathways involved in the bioactive compounds production in subcellular, cellular, organ and whole plant systems during in vivo and in vitro growth, with application in the metabolic engineering of biosynthetic pathways intermediates. Biosynthesis and Manipulation of Bioactive compounds in Medicinal and Aromatic Plants provides a comprehensive introduction and review of the state-of-the-art biotechnological tools used in enhancement of bioactive compounds in medicinal and aromatic plants. Readers will find a systematic overview of techniques such as Omics, Crisper /Cas9 and RNAi to enhance plant bioactive contents including various in vitro techniques, hairy root culture and transgenic technology to enhance plant bioactive contents using plant tissue culture approaches. The chapters provide an overview of the role of induced mutation, biotic and abiotic stress to increase the bioactive contents in plants, plus the role of endophytes to enhance the contents of plant bioactive compounds and standard operating procedures using hydroponics system of cultivation for significant enhancement of bioactive compounds. This book serves as a single source for researchers working in plant secondary metabolites and the pharmaceutical industry.

Download or read book Current Developments in Biotechnology and Bioengineering written by Christian Larroche and published by Elsevier. This book was released on 2016-09-17 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Developments in Biotechnology and Bioengineering: Bioprocesses, Bioreactors and Controls provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, reviewing industrial biotechnology and bioengineering practices that facilitate and enhance the transition of processes from lab to plant scale, which is becoming increasingly important as such transitions continue to grow in frequency. Focusing on industrial bioprocesses, bioreactors for bioprocesses, and controls for bioprocesses, this title reviews industrial practice to identify bottlenecks and propose solutions, highlighting that the optimal control of a bioprocess involves not only maximization of product yield, but also taking into account parameters such as quality assurance and environmental aspects. Describes industrial bioprocesses based on the reaction media Lists the type of bioreactors used for a specific bioprocess/application Outlines the principles of control systems in various bioprocesses

Download or read book Exploring Plant Cells for the Production of Compounds of Interest written by Sonia Malik and published by Springer Nature. This book was released on 2021-04-10 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural compounds obtained from plants represent a tremendous global market due to their use as food additives, cosmetics, in agriculture and in pharmaceuticals. This book provides up-to-date information on various strategies and methods for producing compounds of interest. Leading researchers discuss the latest advances in environmentally friendly natural compound production from plants, making the book a valuable resource for biotechnologists, pharmacists, food technologists and researchers working in the medical and healthcare industries.

Download or read book Production of Plant Derived Natural Compounds through Hairy Root Culture written by Sonia Malik and published by Springer. This book was released on 2017-12-01 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the latest information about hairy root culture and its several applications, with special emphasis on potential of hairy roots for the production of bioactive compounds. Due to high growth rate as well as biochemical and genetic stability, it is possible to study the metabolic pathways related to production of bioactive compounds using hairy root culture. Chapters discuss the feasibility of hairy roots for plant derived natural compounds. Advantages and difficulties of hairy roots for up-scaling studies in bioreactors are included as well as successful examples of hairy root culture of plant species producing bioactive compounds used in food, flavors and pharmaceutical industry. This book is a valuable resource for researchers and students working on the area of plant natural products, phytochemistry, plant tissue culture, medicines, and drug discovery.

Download or read book Nutraceuticals Production from Plant Cell Factory written by Tarun Belwal and published by Springer Nature. This book was released on 2022-06-22 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on in vitro techniques and challenges of producing nutraceutical compounds from plant cells. In addition, it provides an overview of different biosynthesis pathways and their modulation through cell culture techniques for the production of nutraceutical compounds in high quantity and quality. It also includes the assessment of the factors influencing production and advances in cell culture techniques, including the scale-up approach using bioreactors. Lastly it provides valuable suggestion for future research.

Download or read book Hairy Roots written by Vikas Srivastava and published by Springer. This book was released on 2018-11-27 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing scale of plant-based chemicals for industrial use has generated considerable interest in developing methods to meet their desired production levels. Among various available strategies for their production, the development of Agrobacterium rhizogenes mediated hairy root cultures (HRCs) is generally considered the most feasible approach. Additionally, several proof-of-principle experiments have demonstrated the practical feasibility of HRCs in the plant-based remediation of environment pollutants, biotransformation of important compounds, and production of therapeutic proteins. Given that hairy root biotechnology has now been recognized as a promising and highly dynamic research area, this book offers a timely update on recent advances, and approaches hairy roots as a multifaceted biological tool for various applications. Further, it seeks to investigate the loopholes in existing methodologies, identify remaining challenges and find potential solutions by presenting well thought-out scientific discussions from various eminent research groups working on hairy root biotechnology. This book provides detailed conceptual and practical information on HRC-based research, along with relevant case studies. The content is divided into three broad sections, namely (i) Hairy Roots and Secondary Metabolism, (ii) Progressive Applications, and (iii) Novel Approaches and Future Prospects. By informing the research and teaching community about the major strides made in HRC-based interventions in plant biology and their applications, the book is sure to spark further research in this fascinating field.

Download or read book Anticancer Plants Natural Products and Biotechnological Implements written by Mohd Sayeed Akhtar and published by Springer. This book was released on 2018-07-02 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides summarized scientific evidence of the different classes of plant-derived phytocompounds, their sources, chemical structures, anticancer properties, mechanisms of action, methods of extraction, and their applications in cancer therapy. It also discusses endophyte-derived compounds as chemopreventives to treat various cancer types. In addition, it provides detailed information on the enhanced production of therapeutically valuable anticancer metabolites using biotechnological interventions such as plant cell and tissue culture approaches, including in vitro-, hairy root- and cell-suspension culture; and metabolic engineering of biosynthetic pathways. Anticancer Plants: Natural Products and Biotechnological Implements – Volume 2” explores the natural bioactive compounds isolated from plants as well as fungal endophytes, their chemistry, and preventive effects to reduce the risk of cancer. Moreover, it highlights the genomics/proteomics approaches and biotechnological implementations. Providing solutions to deal with the challenges involved in cancer therapy, the book benefits a wide range of readers including academics, students, and industrial experts working in the area of natural products, medicinal plant chemistry, pharmacology, and biotechnology.

Download or read book Bioactive Compounds in Underutilized Vegetables and Legumes written by Hosakatte Niranjana Murthy and published by Springer. This book was released on 2021-07-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work provides a comprehensive overview of bioactive compounds found in underutilized vegetables and legumes around the globe. It describes their pharmacological, biological and health effects in detail, and provides a strategic framework for further research and global development activities. Using a consistent structure and divided into 9 parts based on the plant source, the book reviews bioactive compounds in various plant species. Each part opens with a leading article discussing the respective plant species. This book is a valuable reference resource for plant biologists and biotechnologists, pharmacologists, pharmacists, food technologists, nutritionists and other health professions working in academia and industry.

Download or read book Jasmonic Acid Pathway in Plants written by Kenji Gomi and published by MDPI. This book was released on 2020-04-30 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: The plant hormone jasmonic acid (JA) and its derivative, an amino acid conjugate of JA (jasmonoyl isoleucine, JA-Ile), are signaling compounds involved in the regulation of defense and development in plants. The number of articles studying on JA has dramatically increased since the 1990s. JA is recognized as a stress hormone that regulates the plant response to biotic stresses such as herbivore and pathogen attacks, as well as abiotic stresses such as wounding and ultraviolet radiation. Recent studies have remarkably progressed the understanding of the importance of JA in the life cycle of plants. JA is directly involved in many physiological processes, including stamen growth, senescence, and root growth. JA regulates production of various metabolites such as phytoalexins and terpenoids. Many regulatory proteins involved in JA signaling have been identified by screening for Arabidopsis mutants. However, much more remains to be learned about JA signaling in other plant species. This Special Issue, “Jasmonic Acid Pathway in Plants”, contains 5 review and 15 research articles published by field experts. These articles will help with understanding the crucial roles of JA in its response to the several environmental stresses and development in plants.