Download or read book Production and Characterization of Monoclonal Antibodies to Processing Fragments of a Major Merozoite Surface Coat Precursor Protein GP 195 of Plasmodium Falciparum written by Christopher P. Locher and published by . This book was released on 1988 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Production and Characterization of Monoclonal Antibodies Reactive with Surface and Internal Merozoite Antigens of Plasmodium Falciparum written by Dian Louise Marshall and published by . This book was released on 1984 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1992 with total page 1444 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Malaria written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.
Download or read book Gene Vaccines written by Josef Thalhamer and published by Springer Science & Business Media. This book was released on 2011-08-31 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance. The present book gives an update of the “world of naked gene vaccines”, namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing “burning questions”.
Download or read book Malaria and Babesiosis written by I. Ristic and published by Springer. This book was released on 2012-01-20 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Rodent Malaria written by R. Killick-Kendrick and published by Elsevier. This book was released on 2012-12-02 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rodent Malaria reviews significant findings concerning malaria parasites of rodents, including their taxonomy, zoogeography, and evolution, along with life cycles and morphology; genetics and biochemistry; and concomitant infections. This volume is organized into eight chapters and begins by sketching out the history of the discovery of rodent as well as aspects of parasitology, immunology, and chemotherapy. These concepts are investigated two decades following Ignace Vincke's major discovery and Meir Yoeli's successful establishment of the method of cyclical transmission of the parasite. The following chapters focus on the taxonomy and systematics of the subgenus Vinckeia, with reference to the concepts of species and subspecies of animals and the degree to which they apply to malaria parasites, in particular to those of rodents. The discussion then shifts to how the rodent malaria parasites provide a unique insight into the subcellular organization of Plasmodium species, the use of rodent malaria as an experimental model to study immunological responses, and infectious agents that interact with malaria parasites. The book concludes with a chapter on malaria chemotherapy, with emphasis on the value of rodent malaria in antimalarial drug screening and the use of antimalarial drugs as biological probes. This book will be of interest to protozoologists and physicians as well as those from other disciplines including biochemistry, immunology, pharmacology, cell biology, and genetics.
Download or read book Immunology and Evolution of Infectious Disease written by Steven A. Frank and published by Princeton University Press. This book was released on 2002-07-21 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description
Download or read book Vascular Endothelium written by John D. Catravas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph contains the proceedings from the Advanced Study Institute on "Vascular Endothelium: Physiological Basis of Clinical Problems" which took place in Corfu, Greece in June 1990. The meeting consisted of twenty-eight lectures, most of them adapted as full length papers in this volume, as well as numerous short oral and poster communications which are abstracted and also included in alphabetical order (pages 239-302). There were ninety-six participants from ten NATO and four other European countries. The meeting was the second in as many years dealing with a specific subject in Endothelial Cell biology. Following the 1988 discussion on "Receptors and Transduction Mechanisms", the present ASI recognized and tried to deal with the increasing overlap in interest between basic scientists studying endothelial cell functions and clinicians facing problems of known or suspected endothelial pathological involvement. As with any similar effort, we opted to be selective, rather than fail by trying to be inclusive, in the subjects covered. We chose to discuss diseases, such as atherosclerosis, sepsis, ARDS and stroke, based on their relevance to endothelial cell function and urgent need for new insights into their pathogenesis and treatment. Similarly, we examined endothelial cell functions by considering their relevance to disease and their potential for elucidating important pathologies. Obviously, some areas were covered superficially or not at all; this should not distract from their importance, but rather reflect on the constraints of time and -not at all negligibly -the bias of the organizing committee.
Download or read book Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design written by Sanjeev Kumar Singh and published by Springer Nature. This book was released on 2021-02-02 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents various computer-aided drug discovery methods for the design and development of ligand and structure-based drug molecules. A wide variety of computational approaches are now being used in various stages of drug discovery and development, as well as in clinical studies. Yet, despite the rapid advances in computer software and hardware, combined with the exponential growth in the available biological information, there are many challenges that still need to be addressed, as this book shows. In turn, it shares valuable insights into receptor-ligand interactions in connection with various biological functions and human diseases. The book discusses a wide range of phylogenetic methods and highlights the applications of Molecular Dynamics Simulation in the drug discovery process. It also explores the application of quantum mechanics in order to provide better accuracy when calculating protein-ligand binding interactions and predicting binding affinities. In closing, the book provides illustrative descriptions of major challenges associated with computer-aided drug discovery for the development of therapeutic drugs. Given its scope, it offers a valuable asset for life sciences researchers, medicinal chemists and bioinformaticians looking for the latest information on computer-aided methodologies for drug development, together with their applications in drug discovery.
Download or read book Inclusions in Prokaryotes written by Jessup M. Shively and published by Springer Science & Business Media. This book was released on 2006-05-04 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new series "Microbiology Monographs" begins with two volumes on intracellular components in prokaryotes. In this first volume, "Inclusions in Prokaryotes", the components, labeled inclusions, are defined as discrete bodies resulting from synthesis of a metabolic product. Research on the biosynthesis and reutilization of the accumulated materials is still in progress, and interest in the inclusions is growing. This comprehensive volume provides historical background and comprehensive reviews of eight well-known prokaryotic inclusions.
Download or read book Zoonoses and communicable diseases common to man and animals written by Pedro N. Acha and published by . This book was released on 2003-12-12 with total page 1194 pages. Available in PDF, EPUB and Kindle. Book excerpt: 3 vols also available separately. Contents: Vol. 1 Bacterioses and mycoses (2001, ISBN 927511580X); Vol. 2 Chlamydioses, rickettsioses and viroses (2003, ISBN 927519929); Vol. 3 Parasitoses (2003, ISBN 9275919928)
Download or read book Aptamers for Medical Applications written by Yiyang Dong and published by Springer Nature. This book was released on 2021-03-25 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book outlines comprehensively the main medical uses of aptamers, from diagnosis to therapeutics in fourteen chapters. Pioneering topics covered include aptamer pharmaceuticals, aptamers for malign tumors, aptamers for personalized therapeutics and aptamers for point-of-care testing. The book offers an essential guide for medical scientists interested in developing aptamer-based schemes for better theranostics. It is therefore of interest for not only academic researchers, but also practitioners and medical researchers in various fields of medical science, medical research and bio-analytical chemistry.
Download or read book Peptides and Protein Phosphorylation written by Bruce E. Kemp and published by CRC Press. This book was released on 1990-03-26 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume focuses on the ways in which synthetic peptides have been exploited in order to expand our understanding of the molecular mechanisms involved in protein phosphorylation. It recognizes that virtually all physiological processes are regulated by protein phosphorylation. It discusses the use of synthetic peptides in studying the catalytic mechanism and regulation of protein kinases. It also includes the chemical synthesis of phosphorylated peptides and preparation of specific antisera. This incredible work has lead to the development of a new generation of peptide inhibitors with potencies of greater magnitude than those previously known. Everyone involved with biochemistry and molecular biology will find this one-of-a-kind resource fascinating and filled with useful information.
Download or read book Malaria written by Irwin W. Sherman and published by Amer Society for Microbiology. This book was released on 1998-01 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every 30 seconds a death is caused by Malaria. This book brings together recent advances in our understanding of the basic biology, genetics and pathogenesis of malaria, to facilitate the rapid generation of new insights and interventions. Each chapter is written by a leading expert(s), and serves as both a useful introduction to the area and a helpful set of references. Malaria: Parasite Biology, Pathogenesis and Protection is a useful entry point for graduate and medical students, scientists and individuals engaged in a subspecialty of Malaria research, as well as those who are simply interested in getting a grasp on the present status of this ever burgeoning public health problem.
Download or read book Parasitic Protozoa of Farm Animals and Pets written by Monica Florin-Christensen and published by Springer. This book was released on 2018-04-17 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an in-depth yet concise overview of the most common and emerging protozoa that cause diseases in both farm animals and companion animals. As outlined in the concise introduction, pathogenic protozoans represent an evolutionary highly diverse and little understood group of disease-causing microorganisms. For each of the featured parasitic unicellular eukaryotes, it discusses the morphology, lifecycle, epidemiology and host-pathogen interactions. In addition, the book highlights the latest developments in diagnostic methods, as well as prevention and treatment strategies. Thorough information on genomes and genetic manipulation strategies for some of the protozoa covered in this book is also included. Infections involving parasitic protozoa can cause productivity losses and/or reduce the quality of life of infected animals. Some infections are zoonotic, posing an on-going public health threat. In most cases, prevention and treatment are either non-existent or need considerable improvement. On the other hand, a great deal of research has recently been conducted on these organisms, yielding valuable new information on their global distribution and revealing the mechanisms of host-pathogen interactions at the molecular level – and essential insights that can be used for the development of new control tools. This book includes extensive information on both basic aspects and recent scientific discoveries on these protozoa and thus constitutes a unique resource for students, veterinarians, and researchers alike.
Download or read book Enzyme Biocatalysis written by Andrés Illanes and published by Springer Science & Business Media. This book was released on 2008-06-19 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was written with the purpose of providing a sound basis for the design of enzymatic reactions based on kinetic principles, but also to give an updated vision of the potentials and limitations of biocatalysis, especially with respect to recent app- cations in processes of organic synthesis. The ?rst ?ve chapters are structured in the form of a textbook, going from the basic principles of enzyme structure and fu- tion to reactor design for homogeneous systems with soluble enzymes and hete- geneous systems with immobilized enzymes. The last chapter of the book is divided into six sections that represent illustrative case studies of biocatalytic processes of industrial relevance or potential, written by experts in the respective ?elds. We sincerely hope that this book will represent an element in the toolbox of gr- uate students in applied biology and chemical and biochemical engineering and also of undergraduate students with formal training in organic chemistry, biochemistry, thermodynamics and chemical reaction kinetics. Beyond that, the book pretends also to illustrate the potential of biocatalytic processes with case studies in the ?eld of organic synthesis, which we hope will be of interest for the academia and prof- sionals involved in R&D&I. If some of our young readers are encouraged to engage or persevere in their work in biocatalysis this will certainly be our more precious reward.
