Download or read book Lean Product and Process Development 2nd Edition written by Allen C. Ward and published by Lean Enterprise Institute. This book was released on 2014-03-05 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The P-51 Mustang—perhaps the finest piston engine fighter ever built—was designed and put into flight in just a few months. Specifications were finalized on March 15, 1940; the airfoil prototype was complete on September 9; and the aircraft made its maiden flight on October 26. Now that is a lean development process!" —Allen Ward and Durward Sobek, commenting on the development of the P-51 Mustang and its exemplary use of trade-off curves. Shingo Research and Professional Publication Award recipient, 2008 Despite attempts to interpret and apply lean product development techniques, companies still struggle with design quality problems, long lead times, and high development costs. To be successful, lean product development must go beyond techniques, technologies, conventional concurrent engineering methods, standardized engineering work, and heavyweight project managers. Allen Ward showed the way. In a truly groundbreaking first edition of Lean Product and Process Development, Ward delivered -- with passion and penetrating insights that cannot be found elsewhere -- a comprehensive view of lean principles for developing and sustaining product and process development. In the second edition, Durward Sobek, professor of Mechanical and Industrial Engineering at Montana State University—and one of Ward’s premier students—edits and reorganizes the original text to make it more accessible and actionable. This new edition builds on the first one by: Adding five in-depth and inspiring case studies. Including insightful new examples and illustrations. Updating concepts and tools based on recent developments in product development. Expanding the discussion around the critical concept of set-based concurrent engineering. Adding a more detailed table of contents and an index to make the book more accessible and user-friendly. The True Purpose of Product Development Ward’s core thesis is that the very aim of the product development process is to create profitable operational value streams, and that the key to doing so predictably, efficiently, and effectively is to create useable knowledge. Creating useable knowledge requires learning, so Ward also creates a basic learning model for development. But Ward not only describes the technical tools needed to make lean product and process development actually work. He also delineates the management system, management behaviors, and mental models needed. In this breakthrough text, Ward: Asks fundamental questions about the purpose and “value added” in product development so you gain a crystal clear understanding of essential issues. Shows you how to find the most common forms of “knowledge waste” that plagues product development. Identifies four “cornerstones” of lean product development gleaned from the practices of successful companies like Toyota and its partners, and explains how they differ from conventional practices. Gives you specific, practical recommendations for establishing your own lean development processes. Melds observations of effective teamwork from his military background, engineering fundamentals from his education and personal experience, design methodology from his research, and theories about management and learning from his study of history and experiences with customers. Changes your thinking forever about product development.
Download or read book Practical Process Research and Development written by Neal G. Anderson and published by Academic Press. This book was released on 2012-05-23 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." Second Edition highlights:• Reflects the current thinking in chemical process R&D for small molecules• Retains similar structure and orientation to the first edition. • Contains approx. 85% new material• Primarily new examples (work-up and prospective considerations for pilot plant and manufacturing scale-up)• Some new/expanded topics (e.g. green chemistry, genotoxins, enzymatic processes)• Replaces the first edition, although the first edition contains useful older examples that readers may refer to - Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" - Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more - Presents guidelines for implementing and troubleshooting processes
Download or read book Pharmaceutical Process Development written by John Blacker and published by Royal Society of Chemistry. This book was released on 2011-08-17 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical process research and development is an exacting, multidisciplinary effort but a somewhat neglected discipline in the chemical curriculum. This book presents an overview of the many facets of process development and how recent advances in synthetic organic chemistry, process technology and chemical engineering have impacted on the manufacture of pharmaceuticals. In 15 concise chapters the book covers such diverse subjects as route selection and economics, the interface with medicinal chemistry, the impact of green chemistry, safety, the crucial role of physical organic measurements in gaining a deeper understanding of chemical behaviour, the role of the analyst, new tools and innovations in reactor design, purification and separation, solid state chemistry and its role in formulation. The book ends with an assessment of future trends and challenges. The book provides a valuable overview of: both early and late stage chemical development, how safe and scaleable synthetic routes are designed, selected and developed, the importance of the chemical engineering, analytical and manufacturing interfaces, the key enabling technologies, including catalysis and biocatalysis, the importance of the green chemical perspective and solid form issues. The book, written and edited by experts in the field, is a contemporary, holistic treatise, with a logical sequence for process development and mini-case histories within the chapters to bring alive different aspects of the process. It is completely pharmaceutical themed, encompassing all essential aspects, from route and reagent selection to manufacture of the active compound. The book is aimed at both graduates and postgraduates interested in a career in the pharmaceutical industry. It informs them about the breadth of the work carried out in chemical research and development departments, and gives them a feel for the challenges involved in the job. The book is also of value to academics who often understand the drug discovery arena, but have far less appreciation of the drug development area, and are thus unable to advise their students about the relative merits of careers in chemical development versus discovery.
Download or read book Process Development written by G. Herbert Vogel and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Guiding readers through all steps of the complex process, this book covers the most diverse aspects of chemicals production, including those not or insufficiently covered in natural science courses. These comprise economic feasibility, patenting and licensing, demands on the location and the problem of waste disposal. Throughout, the author does not rely on simple references to other literature but instead reiterates many facts and places them in context, as well as succinctly explaining formulas, thus removing the need to look up items in secondary reference works. As such, the book is suitable for both newcomers as well as those already working in the field. Those working in R&D as well as plant managers will learn how to avoid pitfalls, resulting in higher safety. A common basis and indispensable ready reference for engineers and chemists.
Download or read book Managing New Product and Process Development written by Steven C. Wheelwright and published by Simon and Schuster. This book was released on 2010-07-06 with total page 919 pages. Available in PDF, EPUB and Kindle. Book excerpt: Argues that a company's capability to conceive and design quality prototypes and bring a variety of products to market more quickly than its competitors is increasingly the focal point of competition. The authors present principles for developing speed and efficiency.
Download or read book Development as Process written by John Farrington and published by Routledge. This book was released on 2005-08-16 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Process" approaches to economic and social development appear to be more flexible and offer greater prospects of success than traditional "project" methods. Development as Process addresses the questions raised by the different natures of the two approaches. The authors examine development projects through experience in water resources development in India and in organizational learning by a Bangladeshi NGO. Inter-agency contexts are examined in the setting of an aquaculture project in Bangladesh and in the setting of agriculture and natural resources development in Rajisthan, India. Finally, the role of process monitoring is explained in the context of policy reform, with illustrations from forestry in India and land reform in Russia.
Download or read book Integrated Product and Process Design and Development written by Edward B. Magrab and published by CRC Press. This book was released on 2009-07-28 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of a bestseller, this book discusses an integrated product and process design that has been successfully used to conceptualize, design, and rapidly product competitively-priced quality products. It examines the overlapping, interacting, and iterative nature of the engineering aspects that impact the product realization process. A detailed introduction to the creation of high quality products, the new edition explores the role of innovation, requirements engineering, smart materials, different rapid prototyping methods, and life-cycle cost determination, to name just a few. The book delineates proven methods that have been used successfully to create products.
Download or read book Process Development written by Jerry Carr-Brion and published by Walter de Gruyter GmbH & Co KG. This book was released on 2022-02-21 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by an experienced professional, this book introduces chemists to process development, using examples from the pharmaceutical, agrochemical and fragrance industries. The focus is on small molecules rather than biomolecules, and on relatively small-scale production rather than bulk petrochemicals. The coverage is broad, going from initial route development, through pilot plant operations, to full-scale production.
Download or read book Innovating in Product Process Development written by Mikel Sorli and published by Springer Science & Business Media. This book was released on 2009-07-01 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Innovating in Product/Process Development demonstrates how to achieve true innovation in product development, and how to launch a new product in the quickest and cheapest way. The new approach to product development proposed in this book is based on the most recent research in the field. It suggests the integration of several tools that are currently only used independently, with the aim of stimulating the creation of innovative ideas in general, and specifically in the areas of product/process improvements and problem solving. Innovating in Product/Process Development explores different aspects of innovation processes in twenty-first century industry from a global economic perspective. It presents in detail several approaches to support these processes, from ICT-based systems to collaborative working environments, all of which will be of interest to MBA or advanced students; researchers; and design teams charged with the creation of new product lines.
Download or read book Formulation and Process Development Strategies for Manufacturing Biopharmaceuticals written by Feroz Jameel and published by John Wiley & Sons. This book was released on 2010-08-09 with total page 978 pages. Available in PDF, EPUB and Kindle. Book excerpt: A real-world guide to the production and manufacturing of biopharmaceuticals While much has been written about the science of biopharmaceuticals, there is a need for practical, up-to-date information on key issues at all stages of developing and manufacturing commercially viable biopharmaceutical drug products. This book helps fill the gap in the field, examining all areas of biopharmaceuticals manufacturing, from development and formulation to production and packaging. Written by a group of experts from industry and academia, the book focuses on real-world methods for maintaining product integrity throughout the commercialization process, clearly explaining the fundamentals and essential pathways for all development stages. Coverage includes: Research and early development phase–appropriate approaches for ensuring product stability Development of commercially viable formulations for liquid and lyophilized dosage forms Optimal storage, packaging, and shipping methods Case studies relating to therapeutic monoclonal antibodies, recombinant proteins, and plasma fractions Useful analysis of successful and failed products Formulation and Process Development Strategies for Manufacturing Biopharma-ceuticals is an essential resource for scientists and engineers in the pharmaceutical and biotech industries, for government and regulatory agencies, and for anyone with an interest in the latest developments in the field.
Download or read book Practical Process Research Development written by Neal G. Anderson and published by Academic Press. This book was released on 2000-03 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries. Process R&D describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. More people are being hired for work in this area as increasing numbers of drug candidates are identified through combinatorial chemistry and high-throughput screening. The book is directed to industrial (primarily organic) chemists, and academicians (particularly those involved in a growing number of start-up companies) and students who need insight into industrial process R&D. Current books do not describe hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." "Practical Process Research and Development" will be a valuable resource for researchers, managers, and graduate students. * Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" * Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more * Includes over 100 tips for rapid process development * Presents guidelines for implementing and troubleshooting processes
Download or read book The Development Factory written by Gary P. Pisano and published by Harvard Business Press. This book was released on 1997 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: When the pharmaceuticals giant Merck reports promising results for a potential "blockbuster" drug, the story makes the evening news. Now, at a time when new product development has become critical to success in so many industries, The Development Factory proves that process innovation - not just product innovation - can be the key to competitive edge. In this multiyear study of pharmaceutical and biotechnology firms, Gary Pisano explores the dynamics of superior product and process development in a highly competitive industry that lives and dies by its R&D and depends heavily on rapid time to market. His work reveals that behind the success of many new product introductions lies the development of novel process technologies that provide lower costs, higher quality, and increased flexibility. Pisano challenges the widely held product-process life cycle view of competition, which suggests that industries tend to emphasize either product innovation or process innovation. He also questions the notion that there is a conflict between pursuit of product innovation and pursuit of lower costs, arguing that product development and process development capabilities are complementary. Extending the lessons to a wide variety of manufacturing industries, The Development Factory will guide companies toward unlocking the potential of process development and understanding the patterns of organizational behavior and managerial actions that help create and implement new capabilities over time.
Download or read book The Toyota Product Development System written by James Morgan and published by CRC Press. This book was released on 2020-10-28 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to bring new and innovative products to market rapidly is the prime critical competence for any successful consumer-driven company. All industries, especially automotive, are slashing product development lead times in the current hyper-competitive marketplace. This book is the first to thoroughly examine and analyze the truly effective product development methodology that has made Toyota the most forward-thinking company in the automotive industry. Winner of the 2007 Shingo Prize For Excellence In Manufacturing Research! In The Toyota Product Development System: Integrating People, Process, and Technology, James Morgan and Jeffrey Liker compare and contrast the world-class product development process of Toyota with that of a U.S. competitor. They use extensive examples from Toyota and the U.S. competitor to demonstrate value stream mapping as an extraordinarily powerful tool for continuous improvement. Through examples and case studies, this book illustrates specific techniques and proven practices for dealing with challenges associated with product development, such as synchronizing multiple disciplines, multiple function workload leveling, compound process variation, effective technology integration, and knowledge management. Readers of this book can focus on optimizing the entire product development value stream rather than focus on a specific tool or technology for local improvements.
Download or read book The Development Process written by Akin Mabogunje and published by Routledge. This book was released on 2015-12-14 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written from the perspective of developing countries, this book discusses the development process from a spatial perspective, focussing particularly on the evoltuion of the intra-national space-economy. With emphasis on African nations, this book offers a distinctive interpretation of the current situation and policy prescriptions differing significantly from previous literature in the area.
Download or read book Principles of Process Research and Chemical Development in the Pharmaceutical Industry written by Oljan Repic and published by Wiley-Interscience. This book was released on 1998 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Oljan Repic clearly explains the goals and basic principles of chemical development. He explores the crucial aspects of a new process that must be considered when scaling up a research synthesis to industrial levels. And, with the help of many case studies and vignettes, he delineates each phase of the development process. Key topics include qualities of an ideal process, techniques for minimizing impurities, criteria for cost-effective synthesis of enantiopure compounds by resolutions, asymmetric synthesis and the "chiral pool" strategy, synthesis for labeling substances with hydrogen or carbon isotopes, and new drug registration requirements. This book is an invaluable reference for professionals as well as an important source of guidance and inspiration for young chemists considering entering the field.
Download or read book The Power of Process written by Matthew J. Zayko and published by CRC Press. This book was released on 2021-10-28 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lean Process Creation teaches the specific frames—the 6CON model—to look through to properly design any new process while optimizing the value-creating resources. The framing is applicable to create any process that involves people, technology, or equipment—whether the application is in manufacturing, healthcare, services, retail, or other industries. If you have a process, this approach will help. The result is 30% to 50% improvement in first-time quality, customer lead time, capital efficiency, labor productivity, and floorspace that could add up to millions of dollars saved per year. More important, it will increase both employee and customer satisfaction. The book details a case study from a manufacturing standpoint, starting with a tangible example to reinforce the 6CON model. This is the first book written from this viewpoint—connecting a realistic transformation with the detailed technical challenges, as well as the engagement of the stakeholders, each with their own bias. Key points and must-do actions are sprinkled throughout the case study to reinforce learning from the specific to the general. In this study, an empowered working team is charged with developing a new production line for a critical new product. As the story unfolds, they create an improved process that saves $5.6 million (10x payback on upfront resource investment) over the short life cycle of the product, as well as other measurable benefits in quality, ergonomics, and delivery. To an even greater benefit, they establish a new way of working that can be applied to all future process creation activities. Some organizations have tried their version of Lean process design following a formula or cookie-cutter approach. But true Lean process design goes well beyond forcing concepts and slogans into every situation. It is purposeful, scientific, and adaptable because every situation starts with a unique current state. In addition, Lean process design must include both the technical and social aspects, as they are essential to sustaining and improving any system. Observing the recurring problem of reworking processes that were newly launched brought the authors to the conclusion that a practical book focused on introducing the critical frames of Lean process creation was needed. This book enables readers to consider the details within each frame that must be addressed to create a Lean process. No slogans, no absolutes. Real thinking is required. This type of thinking is best learned from an example, so the authors provide this case study to demonstrate the thinking that should be applied to any process. High volume or low, simple or complex mix, manufacturing or service/transactional—the framing and thinking works. Along with the thinking, readers are enabled to derive their own future states. This is demonstrated in the story that surrounds the case study.
Download or read book Debugging the Development Process written by Steve Maguire and published by . This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laying the groundwork; The systematic approach; Of strategic importance; Unbriedled enthusiasm; Scheduling madness; Constant, unceasing improvement; It's all about attitude; That sinking feeling; References; Index.
