Download or read book Proceedings Tumors of specific sites written by and published by . This book was released on 1975 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tumors of Specific Sites written by and published by . This book was released on 1975 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book WHO Classification of Tumours Digestive System Tumours written by and published by International Agency for Research on Cancer. This book was released on 2019-07-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digestive System Tumours is the first volume in the fifth edition of the WHO series on the classification of human tumors. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumors and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education.
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book The Drug Development Paradigm in Oncology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-02-12 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in cancer research have led to an improved understanding of the molecular mechanisms underpinning the development of cancer and how the immune system responds to cancer. This influx of research has led to an increasing number and variety of therapies in the drug development pipeline, including targeted therapies and associated biomarker tests that can select which patients are most likely to respond, and immunotherapies that harness the body's immune system to destroy cancer cells. Compared with standard chemotherapies, these new cancer therapies may demonstrate evidence of benefit and clearer distinctions between efficacy and toxicity at an earlier stage of development. However, there is a concern that the traditional processes for cancer drug development, evaluation, and regulatory approval could impede or delay the use of these promising cancer treatments in clinical practice. This has led to a number of effortsâ€"by patient advocates, the pharmaceutical industry, and the Food and Drug Administration (FDA)â€"to accelerate the review of promising new cancer therapies, especially for cancers that currently lack effective treatments. However, generating the necessary data to confirm safety and efficacy during expedited drug development programs can present a unique set of challenges and opportunities. To explore this new landscape in cancer drug development, the National Academies of Sciences, Engineering, and Medicine developed a workshop held in December 2016. This workshop convened cancer researchers, patient advocates, and representatives from industry, academia, and government to discuss challenges with traditional approaches to drug development, opportunities to improve the efficiency of drug development, and strategies to enhance the information available about a cancer therapy throughout its life cycle in order to improve its use in clinical practice. This publication summarizes the presentations and discussions from the workshop.
Download or read book Proceedings written by and published by . This book was released on 1958 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms of Carcinogenesis written by Elizabeth K. Weisburger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.
Download or read book AACR 2017 Proceedings Abstracts 1 3062 written by American Association for Cancer Research and published by CTI Meeting Technology. This book was released on 2017-03-13 with total page 3186 pages. Available in PDF, EPUB and Kindle. Book excerpt: The AACR Annual Meeting highlights the best cancer science and medicine from institutions all over the world. Attendees are invited to stretch their boundaries, form collaborations, attend sessions outside their own areas of expertise, and learn how to apply exciting new concepts, tools, and techniques to their own research. Part A contains abstracts 1-3062 accepted for the 2017 meeting.
Download or read book Atlas of Tumors of the Facial Skeleton written by Joachim Prein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rare occurrence of tumors of the facial skeleton, whether of dental origin (odontogenic) or arising from bone (osteogenic), makes it impossible for a single observer to appreciate fully the epi demiologic and clinical behavior of these lesions, even if he controls the case material of a large institution. The systematic cooperation of many scientists is necessary in order to compile a meaningful body of information and make that information accessible for study. On the initiative of one of the authors (B.S.), the German-Austrian Swiss Association for the Study of Tumors of the Face and Jaws (DOSAK) resolved in 1971 to establish a special registry for tumors of the facial skeleton, including odontogenic lesions. This registry has been integrated into the bone tumor registry at the Swiss Asso ciation for Pathology in the Department of Pathology of the Uni versity of Basel. In 1974 DOSAK sponsored a symposium on odontogenic and os teogenic tumors of the jaws, at which illustrative cases were pre sented and discussed. These discussions revealed the problematic nature of these tumors and prompted a number of reclassifications, including some changes from benign to malignant and vice versa. It was found that radical and in some cases mutilating operations would not have been justified on the basis of the new classification. The discussions also underscored the importance of considering all factors - epidemiologic, clinical, radiologic and pathohistologi- when establishing a diagnosis.
Download or read book Bone Tumors written by Andrew G. Huvos and published by . This book was released on 1991 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive 2nd Edition authoritatively describes bone tumors and non-neoplastic bone conditions commonly encountered in practice. Each chapter deals with a major bone tumor, discussing its diagnosis, clinical presentation, roentgenographic findings, histopathology, and treatment. Particular emphasis is placed on lesions of the craniofacial bones, their diagnosis, treatment, and prognosis.
Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Download or read book Tumors of the Ear and Temporal Bone written by Robert K. Jackler and published by . This book was released on 2000 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: This beautifully illustrated volume provides detailed information on all tumors and lesions associated with the ear and temporal bone. The book equips both the general ENT and the specialist with a complete understanding of the presenting signs and symptoms, appropriate imaging and evaluation, and natural history of each type of lesion. With it's excellent chapter organisation and clear, consistent style the book helps the reader to find information easily. Containing over 400 illustrations and numerous tables which complement the text throughout there are also extensive references included
Download or read book Imaging of Bone Tumors and Tumor Like Lesions written by A. Mark Davies and published by Springer Science & Business Media. This book was released on 2009-08-21 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Detection and characterization of bone tumors with imaging remains a big challenge for every radiologist notwithstanding the impressive progress achieved by the introduction of several new imaging modalities. Moreover, new concepts in surgical and oncological treatment of these lesions require from the radiologist appropriate and focused answers to the specifc questions asked by the referring physicians in order to choose the best therapeutic approach for the in- vidual patient. Tis comprehensive textbook describes in detail the possibilities and limits of all moda- ties, including MRI, CT, nuclear medicine and interventional radiological procedures, employed for the modern imaging of tumoral and tumor-like lesions of bone. Teir role in the diagnosis, surgical staging, biopsy and assessment of response to therapy is discussed in detail, covering all tumor subtypes as well as their specifc anatomical location.Well selected and technically imp- cable illustrations strongly enhance the didactic value of this work. I am very much indebted and grateful to the three editors: A. Mark Davies, Murali Sundaram and Steven L. J. James, world authorities in musculoskeletal radiology, for their superb scientifc achievement in preparing and editing this wonderful volume as well as for their individual ch- ters. I would also like to thank the large international group of collaborating authors, who are also widely acknowledged for their specifc expertise in the area of bone tumors, for their outstanding contributions.
Download or read book Current Concepts of Diagnosis and Treatment of Bone and Soft Tissue Tumors written by H. K. Uhthoff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decade, the prognosis of bone and soft tissue tumors has improved considerably. This progress has not only been due to improved therapeutics and diagnostic methods but also due to a team approach now universally adopted. Comparison of results, possible today, were hampered in the past by lack of a clinically relevant staging system and definitive treatment proto cols. The complexity of the therapeutic management of bone tumors re quires a constant exposure to tumors, highly skilled diagnostic tech niques, and specialized expertise. It is therefore not surprising to learn that small and medium-sized hospitals embarking on the diagnosis and treatment of bone and soft tissue tumors are generally less success ful than better equipped major centers. This fact has already been recognized by most physicians and surgeons who now refer their patients to specialized oncologic centers. Nevertheless, they all have to know the present state of the art. This symposium was therefore mostly addressed to them. This international symposium, organized by the Division of Orthopaedic Surgery, University of Ottawa, and cosponsored by the Association des Chirurgiens Orthopedistes du Quebec, was held in Ottawa from May 12-14, 1983. Each of the 40 presentations clearly demonstrates that disregard for proper staging before initiation of treatment and omission of a clearly defined treatment protocol is definitely unacceptable in view of the knowledge we have acquired.
Download or read book Metastatic Cancer Clinical and Biological Perspectives written by Rahul Jandial and published by CRC Press. This book was released on 2013-08-08 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most cancer deaths are a result of metastasis. The spread of a primary tumor to colonize neighboring and distant organs is the relentless endgame that defines the neoplastic process. Patients who have been diagnosed with cancer are treated to prevent both the recurrence of the tumor at the site of origin and metastasis that would re-stage them as advanced stage IV cancer. Historically and still with some types of cancer, stage IV is perceived by patients as “terminal.” Fortunately, recent molecular therapies have extended the lives of patients with advanced cancer and reassuringly people living with metastatic disease increasingly visit our clinics. What is the path forward? Given that the consilience of science and medicine is a dynamic art from which therapies arise, it would be misguided to consider any single work adequate at capturing the horizon for research. So with humility we constructed this text as primer for scientists. It begins with a broad introduction to the clinical management of common cancers. This is intended to serve as a foundation for investigators to consider when developing basic science hypotheses. Unquestionably, medical and surgical care of cancer patients reveals biology and dictates how novel therapeutics will ultimately be evaluated in clinical trials. The second section of this text offers provocative and evolving insights that underscore the breadth of science involved in the elucidation of cancer metastasis biology. The text concludes with information that integrates scientific and clinical foundations to highlight translational research. This book serves as a framework for scientists to conceptualize clinical and translational knowledge on the complexity of disease that is metastatic cancer.
Download or read book Head and Neck Tumor Segmentation written by Vincent Andrearczyk and published by Springer Nature. This book was released on 2021-01-12 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the First 3D Head and Neck Tumor Segmentation in PET/CT Challenge, HECKTOR 2020, which was held in conjunction with the 23rd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2020, in Lima, Peru, in October 2020. The challenge took place virtually due to the COVID-19 pandemic. The 2 full and 8 short papers presented together with an overview paper in this volume were carefully reviewed and selected form numerous submissions. This challenge aims to evaluate and compare the current state-of-the-art methods for automatic head and neck tumor segmentation. In the context of this challenge, a dataset of 204 delineated PET/CT images was made available for training as well as 53 PET/CT images for testing. Various deep learning methods were developed by the participants with excellent results.
Download or read book Mathematical and Computational Oncology written by George Bebis and published by Springer Nature. This book was released on 2021-12-11 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the Third International Symposium on Mathematical and Computational Oncology, ISMCO 2021, held in October 2021. Due to COVID-19 pandemic the conference was held virtually. The 3 full papers and 4 short papers presented were carefully reviewed and selected from 20 submissions. The papers are organized in topical sections named: statistical and machine learning methods for cancer research; mathematical modeling for cancer research; spatio-temporal tumor modeling and simulation; general cancer computational biology; mathematical modeling for cancer research; computational methods for anticancer drug development.
