Download or read book Proceedings of the 8th International Round Table Orange Beach Alabama U S A written by John A. Secrist and published by . This book was released on 1989 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Proceedings of the 8th International Round Table written by and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Proceedings of the 8th International Round Table written by International Round Table [on] Nucleosides, Nucleotides, and Their Biological Applications and published by . This book was released on 1989 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nucleosides nucleotides and their biological applications written by John A. Secrist and published by . This book was released on 1989 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nucleosides Nucleotides and Their Biological Applications written by John A. Secrist and published by . This book was released on 1989 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Advances in Antiviral Drug Design written by E. De Clercq and published by Elsevier. This book was released on 2003-12-17 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth volume of Advances in Antiviral Drug Design is keeping up with the recent progress made in the broad field of antiviral drug research and encompasses six specific directions that have opened new avenues for the treatment of HIV and other virus infections.First, as the introductory chapter, the different new anti-HIV agents that are now in preclinical or clinical development are reviewed by E. De Clercq. This includes new NRTIs, NNRTIs and PIs, but also HIV entry/fusion inhibitors as well as integrase inhibitors, and some of these agents, such as the NRTI emtricitabine [(-)FTC] and the PI atazanavir, may soon be licensed for clinical use.Second, high expectations are vested in the potential therapeutic usefulness of inhibitors of HIV integration, a point of no return in the life cycle of HIV, and this approach is highlighted by D.J. Hazuda and S.D. Young.Third, as all currently available PIs can be described as "peptidomimetic", and, therefore, expected to demonstrate overlapping virus-drug resistance and side effect profiles, it would be interesting to see how a non-peptidic protease inhibitor such as tipranavir behaves, and this is covered by D. Mayers, K. Curry, V. Kohlbrenner and S. McCallister.Fourth, neuraminidase inhibitors such as zanamivir (that has to be inhaled) and oseltamivir (that can be administered via the oral route) have gained a definitive status as antiviral drugs useful for both therapy and prophylaxis of influenza A and B virus infections; as they target a specific influenza viral enzyme, neuraminidase (or sialidase), they may be expected to block newly emerging influenza viruses as well, and the design of neuraminidase inhibitors has received due attention of H. Jin and C.U. Kim.Fifth, while the major current efforts in antiviral drug development have shifted from herpesviruses towards HIV and hepatitis viruses [hepatitis B virus (HBV), hepatitis C virus (HCV)], it is interesting to note that by switching from the classical five-membered sugar or acyclic nucleoside strategy, J. Wang, M. Froeyen and P. Herdewijn have gone "upstream" in designing six-membered carbocyclic nucleosides as potential anti-herpesvirus agents.Sixth, following up on the nucleotide prodrug strategy introduced above under ix, to deliver the biologically active nucleotides inside the cells, C. Meier has elaborated on a particular class of such pronucleotides, namely that of the cyclosaligenyl pronucleotides, an approach that should have far reaching implications for compounds effective against HIV, HBV and other viruses.The six topics covered in this fourth volume of Advances in Antiviral Drug Design are in the front line of the present endeavors towards the design and development of new therapeutic agents for virus infections. They pertain to the combat against three of the most important viral pathogens of current times: HIV, HBV, influenza virus and herpesviruses.

Download or read book Journal of the Chemical Society written by and published by . This book was released on 1989 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Index of Conference Proceedings written by British Library. Document Supply Centre and published by . This book was released on 1994 with total page 984 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1979 with total page 1122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes subject section, name section, and 1968-1970, technical reports.

Download or read book Roundabouts written by Lee August Rodegerdts and published by Transportation Research Board. This book was released on 2010 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: TRB's National Cooperative Highway Research Program (NCHRP) Report 672: Roundabouts: An Informational Guide - Second Edition explores the planning, design, construction, maintenance, and operation of roundabouts. The report also addresses issues that may be useful in helping to explain the trade-offs associated with roundabouts. This report updates the U.S. Federal Highway Administration's Roundabouts: An Informational Guide, based on experience gained in the United States since that guide was published in 2000.

Download or read book The Coding Manual for Qualitative Researchers written by Johnny Saldana and published by SAGE. This book was released on 2009-02-19 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Coding Manual for Qualitative Researchers is unique in providing, in one volume, an in-depth guide to each of the multiple approaches available for coding qualitative data. In total, 29 different approaches to coding are covered, ranging in complexity from beginner to advanced level and covering the full range of types of qualitative data from interview transcripts to field notes. For each approach profiled, Johnny Saldaña discusses the method’s origins in the professional literature, a description of the method, recommendations for practical applications, and a clearly illustrated example.

Download or read book Importing Into the United States written by U. S. Customs and Border Protection and published by . This book was released on 2015-10-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains process of importing goods into the U.S., including informed compliance, invoices, duty assessments, classification and value, marking requirements, etc.

Download or read book Correlations of Soil and Rock Properties in Geotechnical Engineering written by Jay Ameratunga and published by Springer. This book was released on 2015-12-11 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a one-stop reference to the empirical correlations used extensively in geotechnical engineering. Empirical correlations play a key role in geotechnical engineering designs and analysis. Laboratory and in situ testing of soils can add significant cost to a civil engineering project. By using appropriate empirical correlations, it is possible to derive many design parameters, thus limiting our reliance on these soil tests. The authors have decades of experience in geotechnical engineering, as professional engineers or researchers. The objective of this book is to present a critical evaluation of a wide range of empirical correlations reported in the literature, along with typical values of soil parameters, in the light of their experience and knowledge. This book will be a one-stop-shop for the practising professionals, geotechnical researchers and academics looking for specific correlations for estimating certain geotechnical parameters. The empirical correlations in the forms of equations and charts and typical values are collated from extensive literature review, and from the authors' database.

Download or read book Introduction to Probability written by Joseph K. Blitzstein and published by CRC Press. This book was released on 2014-07-24 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developed from celebrated Harvard statistics lectures, Introduction to Probability provides essential language and tools for understanding statistics, randomness, and uncertainty. The book explores a wide variety of applications and examples, ranging from coincidences and paradoxes to Google PageRank and Markov chain Monte Carlo (MCMC). Additional application areas explored include genetics, medicine, computer science, and information theory. The print book version includes a code that provides free access to an eBook version. The authors present the material in an accessible style and motivate concepts using real-world examples. Throughout, they use stories to uncover connections between the fundamental distributions in statistics and conditioning to reduce complicated problems to manageable pieces. The book includes many intuitive explanations, diagrams, and practice problems. Each chapter ends with a section showing how to perform relevant simulations and calculations in R, a free statistical software environment.

Download or read book Air Force Combat Units of World War II written by Maurer Maurer and published by DIANE Publishing. This book was released on 1961 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Proofreading Revising Editing Skills Success in 20 Minutes a Day written by Brady Smith and published by . This book was released on 2017 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In this eBook, you'll learn the principles of grammar and how to manipulate your words until they're just right. Strengthen your revising and editing skills and become a clear and consistent writer." --