Download or read book Jasper s Basic Mechanisms of the Epilepsies written by Jeffrey Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1996 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Non Conventional Yeasts in Genetics Biochemistry and Biotechnology written by Klaus Wolf and published by Springer Science & Business Media. This book was released on 2003-03-04 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most information on yeasts derives from experiments with the conventional yeasts Saccaromyces cerevisiae and Schizossaccharomyces pombe, the complete nuclear and mitochondrial genome of which has also been sequenced. For all other non-conventional yeasts, investigations are in progress and the rapid development of molecular techniques has allowed an insight also into a variety of non-conventional yeasts. In this bench manual, over 70 practical protocols using 15 different non-conventional yeast species and in addition several protocols of general use are described in detail. All of these experiments on the genetics, biochemistry and biotechnology of yeasts have been contributed by renowned laboratories and have been reproduced many times. The reliable protocols are thus ideally suited also for undergraduate and graduate practical courses.
Download or read book New Tools to Interrogate Endocannabinoid Signalling written by Mauro Maccarrone and published by Royal Society of Chemistry. This book was released on 2020-11-06 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Legalization of cannabis extracts around the world has led to a resurgence of interest into research surrounding endocannabinoids (eCBs) and the endocannabinoid system. This system is formed of a complex array of receptors, metabolic enzymes and transporters that finely tune the manifold biological activities of eCBs and there is an urgent need for the development of selective drugs to dissect the contribution of eCBs to the aetiology of various diseases. New Tools to Interrogate Endocannabinoid Signalling comprehensively covers the innovative research into both natural and synthetic compounds that affect this pathway and taking a target-based approach, assesses their potential for therapeutic use. With contributions from global leaders in the field, this timely volume will be a valuable resource to pharmaceutical researchers and medicinal chemists working in natural products and endocannabinoid drug discovery in academia and industry.
Download or read book Genomics of Plants and Fungi written by Rolf A. Prade and published by CRC Press. This book was released on 2003-04-30 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides technical insight on how genomics-oriented studies may be used to bring new understanding to established models of fungal development. The book helps to assess and solve problems associated with multiple copies of genes and proteins with seemingly identical functions and depicts various industrial applications. To bridge the in
Download or read book The National Union Catalog Pre 1956 Imprints written by and published by . This book was released on 1970 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Xenotransplantation written by David K.C. Cooper and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cover of this book depicts a Lamassu, one of the "fabulous" beasts of mythology [1]. Like many similar creatures, such as the Chimera, Griffon, Hippocamp, and Cockatrice, the body of the Lamassu was clearly a combination of structures derived from sev eral different species - in other words, it provides a highly success ful example of xenotransplantation. But in selecting a symbol of xenotransplantation to grace the cover of this volume, why choose the Lamassu in preference to the other ancient beasts? The reason is that the Lamassu appears to have been endowed with a much Fig. I. Homer described the Chimera as consisting of a lion's foreparts, a goat in the middle, and a serpent's hind parts VIII Foreword Fig. 2. The Griffon had the foreparts of an eagle, and the rear, tail, and hindlegs of a lion. Its eagle-like head had pointed, upstanding ears like those of an ass. Feathers grew upon its head, neck and chest, and the rest of its body was covered in leonine fur more benign and desirable character than many of its mythologi cal associates. For example, reliable reports state that the Chimera (Fig. 1) hitherto the animal most commonly selected to symbolize xenografting - killed everyone who came within range of its fiery breath. Perhaps not surprisingly, therefore, the Chimera is vari ously described as one of the "largest monsters ever born," a "sav age creature," and a "symbol of complex evil.
Download or read book Index catalogue of the Library of the Surgeon General s Office United States Army written by National Library of Medicine (U.S.) and published by . This book was released on 1942 with total page 998 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book International Catalogue of Scientific Literature written by and published by . This book was released on 1903 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book International Catalogue of Scientific Literature 1901 1914 written by and published by . This book was released on 1902 with total page 1042 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Yarrowia lipolytica written by Gerold Barth and published by Springer Science & Business Media. This book was released on 2013-07-20 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to various special physiological features and a genome that greatly differs in structure, gene content and organization from other yeasts, Y. lipolytica is widely used as a model organism. With its characteristics, such as the ability to accumulate oil and the high capacity for secretion of proteases and lipases, the yeast is also of great interest for biotechnological applications. The main topics covered in this Microbiology Monograph are: comparative genomics; mitochondrial genomics and proteomics, including the analysis of the respiratory chain; transposable elements and their activities; non-coding RNA genes, which display a number of unusual and remarkable features compared to other hemiascomycetes; utilization of hydrophobic substrates, of n-alkane and its oxidized derivatives as sources of carbon and energy; ambient pH signalling; comparison of protein families in non-conventional yeasts and S. cerevisiae; and the sulphur metabolism of cheese-ripening yeast. .
Download or read book Current List of Medical Literature written by and published by . This book was released on 1947 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.
Download or read book Genomics of Soil and Plant Associated Fungi written by Benjamin A. Horwitz and published by Springer Science & Business Media. This book was released on 2013-08-30 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume addresses the similarities and also the differences in the genomes of soil saprophytes, symbionts, and plant pathogens by using examples of fungal species to illustrate particular principles. It analyzes how the specific interactions with the hosts and the influence of the environment may have shaped genome evolution. The relevance of fungal genetic research and biotechnological applications is shown for areas such as plant pathogenesis, biomass degradation, litter decomposition, nitrogen assimilation, antibiotic production, mycoparasitism, energy, ecology, and also for soil fungi turning to human pathogens. In addition to the model organisms Neurospora and Aspergillus, the following species are covered providing a view of pathogens and mutualists: Trichoderma, Fusarium oxysporum, Cochliobolus heterostrophus, Penicillium chrysogenum, Rhizopus oryzae, Podospora anserina, and species belonging to Agaricomycetes, Archaeorhizomycetes and Magnaporthaceae. Ecology and potential applications have guided the choice of fungal genes to be studied and it will be fascinating to follow the trends of future sequencing projects.
Download or read book Functional Genetics of Industrial Yeasts written by Johannes H. de Winde and published by Springer Science & Business Media. This book was released on 2008-01-26 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, new yeast species have proven their value and novel biotechnological applications have emerged. This book compiles the multi-faceted genetic repertoire of several yeasts relevant to modern biotechnology, and describes their utilization in research and application in the light of their genetic make-up and physiological characteristics. Moreover, the book presents a thorough overview of a wide array of methodologies from classical genetics to modern genomics technologies that have been and are being used in functional analysis of yeasts.
Download or read book Homing Endonucleases and Inteins written by Marlene Belfort and published by Springer Science & Business Media. This book was released on 2008-09-22 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first and only comprehensive description and detailed summary of the genetics, structure, function, mechanisms of action, evolution and engineering of homing endonucleases and inteins. These two unique protein superfamilies, which are tied together through their frequent fusion and coevolution, have generated considerable excitement for their fundamental, structural, and functional properties, their evolution as parasitic elements, and their widespread applications as gene targeting agents and as instruments for the generation of modified proteins and novel protein combinations.
Download or read book Amino Acids written by G. Lubec and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1210 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is little wonder in the fact that the investigation of amino acids is of fundamental interest to scientists from so many diversified fields. If amino acids were only basic constituents of enzymes as well as structural and other proteins, this property alone would elevate them to real scientific importance. Added to this role, however, is their ability to serve as building blocks for the production of many classes of secondary metabolites. They can support the biosynthesis of a myriad of natural products including nonprotein amino acids, cyanogenic glycosides, phar macologically active alkaloids, certain phenols, purines and pyrimidines, nucleic acids, condensed tannins, lignins and other metabolites. The approximately twenty or so amino (and imino) acids that comprise proteins are well known; less familiar are what is now approaching 600 nonprotein amino acids that have been isolated and characterized from plant, fungal or animal sources. Investigations of the protein amino acids have proven of outstanding value in enhancing our understanding of a variety of physiological and neurological topics that affect human health and well being. Amino acids are used to probe inhibitory and excitatory transmission receptors in the brain. They contribute to our understanding of epilepsy, development of anti-epileptic drugs, production of novel y-arninobutyric acid uptake inhibitors, and acute and chronic neurodegenera tive disorders.
