Download or read book Probability Statistics and Modelling in Public Health written by M.S. Nikulin and published by Springer. This book was released on 2005-10-11 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probability, Statistics and Modelling in Public Health consists of refereed contributions by expert biostatisticians that discuss various probabilistic and statistical models used in public health. Many of them are based on the work of Marvin Zelen of the Harvard School of Public Health. Topics discussed include models based on Markov and semi-Markov processes, multi-state models, models and methods in lifetime data analysis, accelerated failure models, design and analysis of clinical trials, Bayesian methods, pharmaceutical and environmental statistics, degradation models, epidemiological methods, screening programs, early detection of diseases, and measurement and analysis of quality of life.

Download or read book Probability Statistics and Modelling in Public Health written by M.S. Nikulin and published by Springer Science & Business Media. This book was released on 2006-02-10 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probability, Statistics and Modelling in Public Health consists of refereed contributions by expert biostatisticians that discuss various probabilistic and statistical models used in public health. Many of them are based on the work of Marvin Zelen of the Harvard School of Public Health. Topics discussed include models based on Markov and semi-Markov processes, multi-state models, models and methods in lifetime data analysis, accelerated failure models, design and analysis of clinical trials, Bayesian methods, pharmaceutical and environmental statistics, degradation models, epidemiological methods, screening programs, early detection of diseases, and measurement and analysis of quality of life.

Download or read book Model based Geostatistics for Global Public Health written by Peter J. Diggle and published by CRC Press. This book was released on 2019-03-04 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Model-based Geostatistics for Global Public Health: Methods and Applications provides an introductory account of model-based geostatistics, its implementation in open-source software and its application in public health research. In the public health problems that are the focus of this book, the authors describe and explain the pattern of spatial variation in a health outcome or exposure measurement of interest. Model-based geostatistics uses explicit probability models and established principles of statistical inference to address questions of this kind. Features: Presents state-of-the-art methods in model-based geostatistics. Discusses the application these methods some of the most challenging global public health problems including disease mapping, exposure mapping and environmental epidemiology. Describes exploratory methods for analysing geostatistical data, including: diagnostic checking of residuals standard linear and generalized linear models; variogram analysis; Gaussian process models and geostatistical design issues. Includes a range of more complex geostatistical problems where research is ongoing. All of the results in the book are reproducible using publicly available R code and data-sets, as well as a dedicated R package. This book has been written to be accessible not only to statisticians but also to students and researchers in the public health sciences. The Authors Peter Diggle is Distinguished University Professor of Statistics in the Faculty of Health and Medicine, Lancaster University. He also holds honorary positions at the Johns Hopkins University School of Public Health, Columbia University International Research Institute for Climate and Society, and Yale University School of Public Health. His research involves the development of statistical methods for analyzing spatial and longitudinal data and their applications in the biomedical and health sciences. Dr Emanuele Giorgi is a Lecturer in Biostatistics and member of the CHICAS research group at Lancaster University, where he formerly obtained a PhD in Statistics and Epidemiology in 2015. His research interests involve the development of novel geostatistical methods for disease mapping, with a special focus on malaria and other tropical diseases. In 2018, Dr Giorgi was awarded the Royal Statistical Society Research Prize "for outstanding published contribution at the interface of statistics and epidemiology." He is also the lead developer of PrevMap, an R package where all the methodology found in this book has been implemented.

Download or read book Applied Spatial Statistics for Public Health Data written by Lance A. Waller and published by John Wiley & Sons. This book was released on 2004-07-29 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: While mapped data provide a common ground for discussions between the public, the media, regulatory agencies, and public health researchers, the analysis of spatially referenced data has experienced a phenomenal growth over the last two decades, thanks in part to the development of geographical information systems (GISs). This is the first thorough overview to integrate spatial statistics with data management and the display capabilities of GIS. It describes methods for assessing the likelihood of observed patterns and quantifying the link between exposures and outcomes in spatially correlated data. This introductory text is designed to serve as both an introduction for the novice and a reference for practitioners in the field Requires only minimal background in public health and only some knowledge of statistics through multiple regression Touches upon some advanced topics, such as random effects, hierarchical models and spatial point processes, but does not require prior exposure Includes lavish use of figures/illustrations throughout the volume as well as analyses of several data sets (in the form of "data breaks") Exercises based on data analyses reinforce concepts

Download or read book Multilevel Modelling of Health Statistics written by A. H. Leyland and published by Wiley. This book was released on 2001-03-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multilevel modelling facilitates the analysis of hierarchical data where observations may be nested within higher levels of classification. In health care research, for example, a study may be undertaken to determine the variability of patient outcomes where these also vary by hospital or health care region. Inference can then be made on the efficacy of health care practices. This book provides the reader with the analytical techniques required to study such data sets. * First book to focus on multilevel modelling for health and medical research * Covers the majority of analytical techniques required by health care professionals * Unifies the literature on multilevel modelling for medical and health researchers * Each contribution comes from a specialist in that area Guiding the reader through various stages, from a basic introduction through to methodological extensions and generalised linear models, this test will show how various kinds of data can be analysed in a multilevel framework. Important statistical concepts, such as sampling and outliers, are covered specifically for multilevel data. Repeated measures, outliers, institutional performance, and spatial analysis, which have great relevance to health and medical research, are all examined for multilevel models. The book is aimed at health care professionals and public health researchers interested in the application of statistics, and will also be of interest to postgraduate students studying medical statistics. Wiley Series in Probability and Statistics

Download or read book Models for Probability and Statistical Inference written by James H. Stapleton and published by John Wiley & Sons. This book was released on 2007-12-14 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise, yet thorough, book is enhanced with simulations and graphs to build the intuition of readers Models for Probability and Statistical Inference was written over a five-year period and serves as a comprehensive treatment of the fundamentals of probability and statistical inference. With detailed theoretical coverage found throughout the book, readers acquire the fundamentals needed to advance to more specialized topics, such as sampling, linear models, design of experiments, statistical computing, survival analysis, and bootstrapping. Ideal as a textbook for a two-semester sequence on probability and statistical inference, early chapters provide coverage on probability and include discussions of: discrete models and random variables; discrete distributions including binomial, hypergeometric, geometric, and Poisson; continuous, normal, gamma, and conditional distributions; and limit theory. Since limit theory is usually the most difficult topic for readers to master, the author thoroughly discusses modes of convergence of sequences of random variables, with special attention to convergence in distribution. The second half of the book addresses statistical inference, beginning with a discussion on point estimation and followed by coverage of consistency and confidence intervals. Further areas of exploration include: distributions defined in terms of the multivariate normal, chi-square, t, and F (central and non-central); the one- and two-sample Wilcoxon test, together with methods of estimation based on both; linear models with a linear space-projection approach; and logistic regression. Each section contains a set of problems ranging in difficulty from simple to more complex, and selected answers as well as proofs to almost all statements are provided. An abundant amount of figures in addition to helpful simulations and graphs produced by the statistical package S-Plus(r) are included to help build the intuition of readers.

Download or read book Statistical Models in Epidemiology written by David Clayton and published by Oxford University Press, USA. This book was released on 2013-01-17 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This self-contained account of the statistical basis of epidemiology has been written for those with a basic training in biology. It is specifically intended for students enrolled for a masters degree in epidemiology, clinical epidemiology, or biostatistics.

Download or read book Biostatistics for Clinical and Public Health Research written by Melody S. Goodman and published by Routledge. This book was released on 2017-12-14 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biostatistics for Clinical and Public Health Research provides a concise overview of statistical analysis methods. Use of SAS and Stata statistical software is illustrated in full, including how to interpret results. Focusing on statistical models without all the theory, the book is complete with exercises, case studies, take-away points, and data sets. Readers will be able to maximize their statistical abilities in hypothesis testing, data interpretation, and application while also learning when and how to consult a biostatistician. This book will be an invaluable tool for students and clinical and public health practitioners.

Download or read book Statistics In the Pharmaceutical Industry 3rd Edition written by C. Ralph Buncher and published by CRC Press. This book was released on 2005-09-28 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growth of the pharmaceutical industry over the past decade is astounding, but the impact of this growth on statistics is somewhat confusing. While software has made analysis easier and more efficient, regulatory bodies now demand deeper and more complex analyses, and pharmacogenetic/genomic studies serve up an entirely new set of challenges. For more than two decades, Statistics in the Pharmaceutical Industry has been the definitive guide to sorting through the challenges in the industry, and this Third Edition continues that tradition. Updated and expanded to reflect the most recent trends and developments in the field, Statistics in the Pharmaceutical Industry, Third Edition presents chapters written by experts from both regulatory agencies and pharmaceutical companies who discuss everything from experimental design to post-marketing studies. This approach sheds light on what regulators consider acceptable methodologies and what methods have proven successful for industrial statisticians. Both new and revised chapters reflect the increasingly global nature of the industry as represented by authors from Japan and Europe, the increasing trend toward non-inferiority/equivalence testing, adaptive design in clinical trials, global harmonization of regulatory standards, and multiple comparison studies. The book also examines the latest considerations in anti-cancer studies. Statistics in the Pharmaceutical Industry, Third Edition demystifies the approval process by combining regulatory and industrial points of view, making it a must-read for anyone performing statistical analysis at any point in the drug approval process.

Download or read book Modelling in Healthcare written by and published by American Mathematical Soc.. This book was released on 2010 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: A model is a simplified representation of a real-world situation used to help answer a specific question. This book provides a look into the world of modelling with the focus on modelling in healthcare.--[from preface]

Download or read book Statistical Models and Methods for Biomedical and Technical Systems written by Filia Vonta and published by Springer Science & Business Media. This book was released on 2008-03-05 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the mathematical aspects of survival analysis and reliability as well as other topics, reflecting recent developments in the following areas: applications in epidemiology; probabilistic and statistical models and methods in reliability; models and methods in survival analysis, longevity, aging, and degradation; accelerated life models; quality of life; new statistical challenges in genomics. The work will be useful to a broad interdisciplinary readership of researchers and practitioners in applied probability and statistics, industrial statistics, biomedicine, biostatistics, and engineering.

Download or read book Everyday Probability and Statistics written by M. M. Woolfson and published by Imperial College Press. This book was released on 2008 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probability and statistics impinge on the life of the average person in a variety of ways OCo as is suggested by the title of this book. Very often, information is provided that is factually accurate but intended to present a biased view. This book presents the important results of probability and statistics without making heavy mathematical demands on the reader. It should enable an intelligent reader to properly assess statistical information and to understand that the same information can be presented in different ways.

Download or read book Applied Survival Analysis written by David W. Hosmer, Jr. and published by John Wiley & Sons. This book was released on 2011-09-23 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE MOST PRACTICAL, UP-TO-DATE GUIDE TO MODELLING AND ANALYZING TIME-TO-EVENT DATA—NOW IN A VALUABLE NEW EDITION Since publication of the first edition nearly a decade ago, analyses using time-to-event methods have increase considerably in all areas of scientific inquiry mainly as a result of model-building methods available in modern statistical software packages. However, there has been minimal coverage in the available literature to9 guide researchers, practitioners, and students who wish to apply these methods to health-related areas of study. Applied Survival Analysis, Second Edition provides a comprehensive and up-to-date introduction to regression modeling for time-to-event data in medical, epidemiological, biostatistical, and other health-related research. This book places a unique emphasis on the practical and contemporary applications of regression modeling rather than the mathematical theory. It offers a clear and accessible presentation of modern modeling techniques supplemented with real-world examples and case studies. Key topics covered include: variable selection, identification of the scale of continuous covariates, the role of interactions in the model, assessment of fit and model assumptions, regression diagnostics, recurrent event models, frailty models, additive models, competing risk models, and missing data. Features of the Second Edition include: Expanded coverage of interactions and the covariate-adjusted survival functions The use of the Worchester Heart Attack Study as the main modeling data set for illustrating discussed concepts and techniques New discussion of variable selection with multivariable fractional polynomials Further exploration of time-varying covariates, complex with examples Additional treatment of the exponential, Weibull, and log-logistic parametric regression models Increased emphasis on interpreting and using results as well as utilizing multiple imputation methods to analyze data with missing values New examples and exercises at the end of each chapter Analyses throughout the text are performed using Stata® Version 9, and an accompanying FTP site contains the data sets used in the book. Applied Survival Analysis, Second Edition is an ideal book for graduate-level courses in biostatistics, statistics, and epidemiologic methods. It also serves as a valuable reference for practitioners and researchers in any health-related field or for professionals in insurance and government.

Download or read book Bayesian Statistical Modelling written by P. Congdon and published by . This book was released on 2001-05-02 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian methods draw upon previous research findings and combine them with sample data to analyse problems and modify existing hypotheses. The calculations are often extremely complex, with many only now possible due to recent advances in computing technology. Bayesian methods have as a result gained wider acceptance, and are applied in many scientific disciplines, including applied statistics, public health research, medical science, the social sciences and economics. Bayesian Statistical Modelling presents an accessible overview of modelling applications from a Bayesian perspective. * Provides an integrated presentation of theory, examples and computer algorithms * Examines model fitting in practice using Bayesian principles * Features a comprehensive range of methodologies and modelling techniques * Covers recent innovations in bayesian modelling, including Markov Chain Monte Carlo methods * Includes extensive applications to health and social sciences * Features a comprehensive collection of nearly 200 worked examples * Data examples and computer code in WinBUGS are available via ftp Whilst providing a general overview of Bayesian modelling, the author places emphasis on the principles of prior selection, model identification and interpretation of findings, in a range of modelling innovations, focussing on their implementation with real data, with advice as to appropriate computing choices and strategies. Researchers in applied statistics, medical science, public health and the social sciences will benefit greatly from the examples and applications featured. The book will also appeal to graduate students of applied statistics, data analysis and Bayesian methods, and will provide a good reference source for both researchers and students.

Download or read book Mathematical Epidemiology written by Fred Brauer and published by Springer Science & Business Media. This book was released on 2008-04-30 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on lecture notes of two summer schools with a mixed audience from mathematical sciences, epidemiology and public health, this volume offers a comprehensive introduction to basic ideas and techniques in modeling infectious diseases, for the comparison of strategies to plan for an anticipated epidemic or pandemic, and to deal with a disease outbreak in real time. It covers detailed case studies for diseases including pandemic influenza, West Nile virus, and childhood diseases. Models for other diseases including Severe Acute Respiratory Syndrome, fox rabies, and sexually transmitted infections are included as applications. Its chapters are coherent and complementary independent units. In order to accustom students to look at the current literature and to experience different perspectives, no attempt has been made to achieve united writing style or unified notation. Notes on some mathematical background (calculus, matrix algebra, differential equations, and probability) have been prepared and may be downloaded at the web site of the Centre for Disease Modeling (www.cdm.yorku.ca).

Download or read book Uncertainty written by William Briggs and published by Springer. This book was released on 2016-07-15 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a philosophical approach to probability and probabilistic thinking, considering the underpinnings of probabilistic reasoning and modeling, which effectively underlie everything in data science. The ultimate goal is to call into question many standard tenets and lay the philosophical and probabilistic groundwork and infrastructure for statistical modeling. It is the first book devoted to the philosophy of data aimed at working scientists and calls for a new consideration in the practice of probability and statistics to eliminate what has been referred to as the "Cult of Statistical Significance." The book explains the philosophy of these ideas and not the mathematics, though there are a handful of mathematical examples. The topics are logically laid out, starting with basic philosophy as related to probability, statistics, and science, and stepping through the key probabilistic ideas and concepts, and ending with statistical models. Its jargon-free approach asserts that standard methods, such as out-of-the-box regression, cannot help in discovering cause. This new way of looking at uncertainty ties together disparate fields — probability, physics, biology, the “soft” sciences, computer science — because each aims at discovering cause (of effects). It broadens the understanding beyond frequentist and Bayesian methods to propose a Third Way of modeling.

Download or read book Spatiotemporal Environmental Health Modelling A Tractatus Stochasticus written by George Christakos and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spatiotemporal Environmental Health Modelling: A Tractatus Stochasticus provides a holistic, conceptual and quantitative framework for Environmental Health Modelling in space-time. The holistic framework integrates two aspects of Environmental Health Science that have been previously treated separately: the environmental aspect, which involves the natural processes that bring about human exposure to harmful substances; and the health aspect, which focuses on the interactions of these substances with the human body. Some of the fundamental issues addressed in this work include variability, scale, uncertainty, and space-time connectivity. These topics are important in the characterization of natural systems and health processes. Spatiotemporal Environmental Health Modelling: A Tractatus Stochasticus explains why modern stochastics is the appropriate mechanical vehicle for addressing such issues in a rigorous way. In particular, modern stochastics incorporates concepts and methods from probability, classical statistics, geostatistics, statistical mechanics and field theory. The authors present a synthetic view of environmental health that embraces all of the various components and focuses on their mutual interactions. Spatiotemporal Environmental Health Modeling: A Tractatus Stochasticus includes new material on Bayesian maximum entropy estimation techniques and space-time random field estimation methods. The authors show why these methods have clear advantages over the classical geostatistical estimation procedures and how they can be used to provide accurate space-time maps of environmental health processes. Also included are expositions of diagrammatic perturbation and renormalization group analysis, which have not been previously discussed within the context of Environmental Health. Finally, the authors present stochastic indicators that can be used for large-scale characterization of contamination and investigations of health effects at the microscopic level. This book will be a useful reference to both researchers and practitioners of Environmental Health Sciences. It will appeal specifically to environmental engineers, geographers, geostatisticians, earth scientists, toxicologists, epidemiologists, pharmacologists, applied mathematicians, physicists and biologists.