Download or read book Principles of Biochemical Toxicology Fourth Edition written by John A. Timbrell and published by CRC Press. This book was released on 2008-11-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This leading textbook in the field examines the mechanisms underlying toxicity, particularly the events at the molecular level and the factors that determine and affect toxicity. The new edition is updated to reflect the latest research into the biochemical basis of toxicology and the growing concerns over the adverse effects of drugs, environmental pollution, and occupational hazards. Principles of Biochemical Toxicology, Fourth Edition thoroughly explains dose-response relationships, disposition and metabolism, and toxic responses to foreign compounds, and presents detailed examples to make the mechanisms of toxicity more accessible to students encountering the subject for the first time. Comprehensive in scope with a clear and concise approach, the text includes summary sections, questions and model answers, and thoroughly revised artwork that serves as an essential aid to learning and teaching. New to the Fourth Edition: reorganized sections that cover basic principles followed by sections on different types of toxicity extensive use of examples throughout and numerous explanatory diagrams new material on risk assessment, export systems, oxidative stress, Thalidomide, Tamoxifen and asbestos proliferators, domoic acid, bone marrow (benzene), heart (adriamycin), blood (primaquine), biomarkers, cytochrome P450 and other enzymes, receptor mediated effects, endocrine disruption, ethanol, botox, arsenic, and more questions with answers for each chapter for review and self-checking expanded and updated chapter bibliographies
Download or read book Principles of Biochemical Toxicology Third Edition written by John Timbrell and published by CRC Press. This book was released on 1999-10-21 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards. Following on from the acclaimed first two editions of Principles of Biochemical Toxicology, John Timbrell has expanded the text to include: summary sections questions and model answers thoroughly revised artwork These features, plus the new easy-to-read format will make biochemical toxicology more accessible to undergraduates and postgraduates coming across the subject for the first time, particularly when undertaking self-directed study. This comprehensive textbook provides a thorough explanation of dose-response relationships; disposition and metabolism; toxic responses to foreign compounds, and detailed examples to illustrate mechanisms of toxicity. There is also an expanded and updated bibliography, directing the reader to further reading if required. Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field, an essential aid to learning and teaching.
Download or read book Introduction to Toxicology Third Edition written by John Timbrell and published by CRC Press. This book was released on 2001-11-15 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.
Download or read book Principles of Biochemical Toxicology written by John A. Timbrell and published by . This book was released on 1999 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading textbook in biochemical toxicology. Addresses dose-response relationships; metabolism; toxic responses, and provides detailed examples to illustrate mechanisms of toxicity.
Download or read book Principles of Biochemical Toxicology written by John Timbrell and published by CRC Press. This book was released on 1999-11-01 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading textbook in biochemical toxicology. Addresses dose-response relationships; metabolism; toxic responses, and provides detailed examples to illustrate mechanisms of toxicity.
Download or read book Molecular and Biochemical Toxicology written by Robert C. Smart and published by John Wiley & Sons. This book was released on 2018-01-04 with total page 1060 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written as an advanced text for toxicology students, this book is much more than an introduction and provides in-depth information describing the underlying mechanisms through which toxicants produce their adverse responses. • Links traditional toxicology to modern molecular techniques, important for teaching to graduate courses and professional studies • Uses a didactic approach with basic biological or theoretical background for the methodology presented • Brings together and comprehensively covers a range of dynamic aspects in biochemical and molecular toxicology • Guides student and professional toxicologists in comprehending a broad range of issues, compiled and authored by a diverse group of experts • “A good introductory textbook covering the biochemical toxicology of organic substances and the relevant methodology in some detail.... It offers good value for money and can be recommended as a textbook for appropriate courses” – BTS Newsletter review of the 4th edition
Download or read book Principles of Biochemical Toxicology Second Edition written by John Timbrell and published by CRC Press. This book was released on 1991-10-28 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text, drawing upon the range of toxicology literature, sets down the fundamental principles of toxicology and pharmacology and goes on to cover recent developments in the field. The emphasis of the book is on biomechanical mechanisms. This second edition contains more examples.
Download or read book Introduction to Toxicology written by John Timbrell and published by CRC Press. This book was released on 2019-10-30 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.
Download or read book Principles of Ecotoxicology Fourth Edition written by C.H. Walker and published by CRC Press. This book was released on 2012-03-12 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cutting across traditional subject boundaries, Principles of Ecotoxicology, Fourth Edition gives readers an integrated view of ecotoxicology, from molecules to ecosystems. This new edition of a bestselling textbook continues to emphasize principles rather than practice, providing the interdisciplinary perspective and grounding required for research. Organized into three sections, the book first describes the molecular structures, properties, and environmental fate of pollutants. It then deals with the effects of pollutants on living organisms at the molecular, cellular, and individual levels. Moving into population biology and population genetics, the third part of the book addresses a question of great interest to ecologists: What effects do pollutants have at the levels of population, community, and the whole ecosystem? The book also looks at how ecotoxicology is used in the biomonitoring of environmental pollution, the investigation of pollution problems, the conducting of field trials, the study of the development of resistance, and the growing area of environmental risk assessments. Throughout, examples and case studies illustrate the principles. This updated fourth edition includes new material on nanoparticle pollution, bioaccumulation, biomarkers, and chemical warfare in nature, as well as a new chapter on the future directions of ecotoxicology. A concise textbook that will also appeal to practicing ecotoxicologists, it provides a solid basis for understanding what happens to chemicals in the real world, where they go, how they ultimately degrade, and how they affect the individuals and populations that encounter them. What’s New in This Edition Revised and updated material throughout A chapter on future directions of ecotoxicology New material on nanoparticle pollution and chemical warfare in nature Expanded coverage of bioaccumulation, biomarkers, and risk assessment for affected populations More case studies, many from the United States Discussion of neurotoxic and behavioral effects of pollutants Recent research on the decline of vultures and effects of neonicotinoids on bees Organic Pollutants: An Ecotoxicological Perspective, Second Edition (CRC Press, 2008), a companion volume to this book, covers the mechanistic aspects of ecotoxicology in more depth.
Download or read book A Textbook of Modern Toxicology written by Ernest Hodgson and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Textbook of Modern Toxicology is a unique resource that provides both students and practitioners with a wide-ranging, accessible overview of the discipline. Suitable for courses in environmental, pharmacological, medical, and veterinary toxicology, this essential text features chapters written by experts who address a range of key topics. The Fourth Edition includes additional chapters on new approaches to toxicology - molecular methods (-omics: toxicogenomics, proteomics, and metabolomics), bioinformatics, and systems biology – and continues the legacy of its predecessors to provide up-to-date insights into acute toxicity and chemical carcinogenesis, organ toxicity, in vitro and in vivo toxicity testing, ecological risk assessment, and many other areas of toxicology that help foster a solid comprehension of the field. Also featured in the Fourth Edition are end-of-chapter questions and a Solutions Manual available separately for academic adopters.
Download or read book Principles of Toxicology Second Edition written by Stine Karen and published by CRC Press. This book was released on 2006-01-24 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by two experienced toxicology lecturers, Principles of Toxicology provides a broad-based yet in-depth introduction to this diverse subject. Comprehensive and easy-to-read, the book covers this broad and interdisciplinary field from the viewpoint of three different functional levels: molecular and cellular; physiological; and ecological and environmental. This revised second edition expands the coverage of the book while keeping the organizational format that made the first edition a bestseller. It also includes a series of brief case studies illustrating the application of toxicological principles to current issues of interest. Each and every chapter has been revised, several have been significantly rewritten, and three are entirely new. This new edition retains the extensive cross-referencing system that links all sections and enhances the integration of material. It also includes an appendix of selected toxicants that describes chemical structure and category of use. These features combine to make finding specific information quick and easy. The highly readable format and uniform, consistent presentation of information will make this the most used reference on your shelf. See what's new in the second edition:
Download or read book A Textbook of Modern Toxicology written by Ernest Hodgson and published by . This book was released on 1987 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed as an introductory textbook, the book emphasizes the fundamental basis of toxic action at the cellular and molecular levels and lays the foundation for specialized courses in toxicology.
Download or read book Toxicology Principles for the Industrial Hygienist written by William E. Luttrell and published by AIHA. This book was released on 2008 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focuses on the applications of toxicology principles to the practice of industrial hygiene, using case studies as examples.
Download or read book Principles of Ecotoxicology Second Edition written by C.H. Walker and published by CRC Press. This book was released on 2003-09-02 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade ecotoxicology has emerged as a distinct subject of interdisciplinary character. Courses in ecotoxicology reflect this and are taught by specialists in chemistry and biochemistry through to population genetics and ecology. As the first textbook to incorporate all relevant aspects of chemistry, biochemistry, toxicology, physiology, population ecology and population genetics, the first edition of this book proved to be well received across several industries. Featuring fully revised text and new illustrations, Principles of Ecotoxicology identifies the major classes of organic and inorganic pollutants, their properties, release and environmental fate, and transport in air, water and along food chains, before considering the effects that they might have upon individual organisms and ultimately whole ecosystems. This timely second edition of Principles of Ecotoxicology incorporates data collected since the first edition on subjects of current research and media interest such as organochloride pesticides, endocrine disruptors, aquatic toxicity, industrial waste and ecotoxicity testing.
Download or read book Principles of Toxicology written by Stephen M. Roberts and published by John Wiley & Sons. This book was released on 2022-04-05 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Toxicology concisely and efficiently presents the scientific basis for toxicology as it applies to the workplace and the environment, covering diverse chemical hazards encountered in modern workplaces and natural environments and providing a practical understanding of these hazards for those concerned with protecting the health of humans and ecosystems. The work presents not only theory, but also practical information regarding chemical hazards to give the student and new professional a working knowledge of the practice of toxicology and the ability to solve problems in environmental and industrial settings. Case histories and examples from industrial and environmental exposures to chemicals are included to demonstrate the application of toxicological principles. To allow for seamless reader comprehension and further exploration of covered topics, the work is supplemented with numerous illustrations to clarify and summarize key points, as well as annotated bibliographies. In the 4th edition, all chapters and references have been updated to account for the latest scientific thinking, and new color figures have been added. New topics covered in 4th Edition of Principles of Toxicology include: Regulatory toxicology, including the key regulatory framework in which much of the field of toxicology operates Alternative methods in toxicology, including cutting-edge approaches to developing new information on the toxicity of drugs and chemicals The dilemma of selecting safe exposure limits, guiding readers through practical considerations and pitfalls in developing and using safe exposure limits Ecological risk assessment, with detailed discussion of methods and considerations when evaluating the effects of contaminants on plants and animals. Providing information on the principles of toxicology and the application of those principles to solve problems in environmental and industrial settings, Principles of Toxicology serves as an excellent textbook resource for advanced undergraduate, graduate, and professional students in a range of environmental and health fields. It is also valuable to health professionals who need toxicological information and assistance beyond what is found in an introductory text to general toxicology.
Download or read book Principles of Ecotoxicology written by C.H. Walker and published by CRC Press. This book was released on 1996-04-11 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental pollution is caused by a wide range of chemicals released as a consequence of human activities. This book aims to identify major classes of pollutants and their environmental fate, before going on to consider the effects that they might have on individual organisms and ecosystems. The book progresses from the molecular basis of pollutant toxicity to consequent effects at higher levels of organization - cellular, whole organism, population, community and ecosystem.; The book defines ecotoxicology as the study of the harmful effects of chemicals upon ecosystems. It is an interdisciplinary subject which represents a synthesis of elements from the disciplines of chemistry, biochemistry, toxicology, physiology, population ecology and population genetics. In contrast to "classical" toxicology, the ultimate concern is for the effects at the level of populations and consequent effects at the level of populations.
Download or read book Mechanistic Toxicology written by Urs A. Boelsterli and published by CRC Press. This book was released on 2007-03-23 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology
