Download or read book Principles of Bacterial Detection Biosensors Recognition Receptors and Microsystems written by Mohammed Zourob and published by Springer Science & Business Media. This book was released on 2008-09-03 with total page 980 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems will cover the up-to-date biosensor technologies used for the detection of bacteria. Written by the world's most renowned and learned scientists each in their own area of expertise, Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems is the first title to cover this expanding research field.
Download or read book Anomaly Detection Principles and Algorithms written by Kishan G. Mehrotra and published by Springer. This book was released on 2017-11-18 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a readable and elegant presentation of the principles of anomaly detection,providing an easy introduction for newcomers to the field. A large number of algorithms are succinctly described, along with a presentation of their strengths and weaknesses. The authors also cover algorithms that address different kinds of problems of interest with single and multiple time series data and multi-dimensional data. New ensemble anomaly detection algorithms are described, utilizing the benefits provided by diverse algorithms, each of which work well on some kinds of data. With advancements in technology and the extensive use of the internet as a medium for communications and commerce, there has been a tremendous increase in the threats faced by individuals and organizations from attackers and criminal entities. Variations in the observable behaviors of individuals (from others and from their own past behaviors) have been found to be useful in predicting potential problems of various kinds. Hence computer scientists and statisticians have been conducting research on automatically identifying anomalies in large datasets. This book will primarily target practitioners and researchers who are newcomers to the area of modern anomaly detection techniques. Advanced-level students in computer science will also find this book helpful with their studies.
Download or read book Sharing Clinical Trial Data written by Institute of Medicine and published by National Academies Press. This book was released on 2015-04-20 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research-from funders, to researchers, to journals, to physicians, and ultimately, to patients.
Download or read book Outlier Detection Techniques and Applications written by N. N. R. Ranga Suri and published by Springer. This book was released on 2019-01-10 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, drawing on recent literature, highlights several methodologies for the detection of outliers and explains how to apply them to solve several interesting real-life problems. The detection of objects that deviate from the norm in a data set is an essential task in data mining due to its significance in many contemporary applications. More specifically, the detection of fraud in e-commerce transactions and discovering anomalies in network data have become prominent tasks, given recent developments in the field of information and communication technologies and security. Accordingly, the book sheds light on specific state-of-the-art algorithmic approaches such as the community-based analysis of networks and characterization of temporal outliers present in dynamic networks. It offers a valuable resource for young researchers working in data mining, helping them understand the technical depth of the outlier detection problem and devise innovative solutions to address related challenges.
Download or read book Hayes Principles and Methods of Toxicology Sixth Edition written by A. Wallace Hayes and published by CRC Press. This book was released on 2014-10-10 with total page 2186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hayes’ Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chapters that address the advances and developments since the fifth edition, the book presents everything toxicologists and students need to know to understand hazards and mechanisms of toxicity, enabling them to better assess risk. The book begins with the four basic principles of toxicology—dose matters, people differ, everything transforms, and timing is crucial. The contributors discuss various agents of toxicity, including foodborne, solvents, crop protection chemicals, radiation, and plant and animal toxins. They examine various methods for defining and measuring toxicity in a host of areas, including genetics, carcinogenicity, toxicity in major body systems, and the environment. This new edition contains an expanded glossary reflecting significant changes in the field. New topics in this edition include: The importance of dose–response Systems toxicology Food safety The humane use and care of animals Neurotoxicology The comprehensive coverage and clear writing style make this volume an invaluable text for students and a one-stop reference for professionals.
Download or read book Principles and Applications of Molecular Diagnostics written by Nader Rifai and published by Elsevier. This book was released on 2018-06-13 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Applications of Molecular Diagnostics serves as a comprehensive guide for clinical laboratory professionals applying molecular technology to clinical diagnosis. The first half of the book covers principles and analytical concepts in molecular diagnostics such as genomes and variants, nucleic acids isolation and amplification methods, and measurement techniques, circulating tumor cells, and plasma DNA; the second half presents clinical applications of molecular diagnostics in genetic disease, infectious disease, hematopoietic malignancies, solid tumors, prenatal diagnosis, pharmacogenetics, and identity testing. A thorough yet succinct guide to using molecular testing technology, Principles and Applications of Molecular Diagnostics is an essential resource for laboratory professionals, biologists, chemists, pharmaceutical and biotech researchers, and manufacturers of molecular diagnostics kits and instruments. - Explains the principles and tools of molecular biology - Describes standard and state-of-the-art molecular techniques for obtaining qualitative and quantitative results - Provides a detailed description of current molecular applications used to solve diagnostics tasks
Download or read book Solid State Nuclear Track Detection written by S. A. Durrani and published by Pergamon. This book was released on 1987 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid State Nuclear Track Detection: Principles, Methods and Applications is the second book written by the authors after Nuclear Tracks in Solids: Principles and Applications. The book is meant as an introduction to the subject solid state of nuclear track detection. The text covers the interactions of charged particles with matter; the nature of the charged-particle track; the methodology and geometry of track etching; thermal fading of latent damage trails on tracks; the use of dielectric track recorders in particle identification; radiation dossimetry; and solid state nuclear track detecti ...
Download or read book Chemical Mutagens written by Alexander Hollaender and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: The best protection against environmental mutagens is to identify them before they ever come into general use. But it is always possible that some substance will escape detection and affect a large number of persons without this being realized until later generations. This article considers ways in which such a genetic emergency might be promptly detected. A mutation-detecting system should be relevant in that it tests for effects that are as closely related as possible to those that are feared. It should be sensitive enough to detect a moderate increase in mutation rate, able to discover the increase promptly before more damage is done, responsive to various kinds of mutational events, and designed in such a way as to maxi mize the probability that the Gause of an increase can be found. Methods based on germinal mutation necessarily involve enormous numbers of persons and tests. On the other hand, with somatic mutations the individual cell becomes the unit of measurement rather than the in dividual person. For this reason, I think that somatic tests are preferable to germinal tests, despite the fact that it is germinal mutations which are feared.
Download or read book Principles and Methods for Assessing Autoimmunity Associated with Exposure to Chemicals written by International Labour Organisation and published by World Health Organization. This book was released on 2006 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document provides an introduction to the field of transgenic mutagenicity assays and assesses the possible role of these assays in toxicology testing and mechanistic research. Part I gives a short overview of in vivo genotoxicity testing. Part II gives an overview of the data produced by various assays. Part III discusses the use of the assays in research. Part IV evaluates the role and potential added value of transgenic mutation assays in toxicology and risk assessment. This document is directed at toxicologists, research scientists and risk assessors.--Publisher's description.
Download or read book The Polygraph and Lie Detection written by National Research Council and published by National Academies Press. This book was released on 2003-01-22 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: The polygraph, often portrayed as a magic mind-reading machine, is still controversial among experts, who continue heated debates about its validity as a lie-detecting device. As the nation takes a fresh look at ways to enhance its security, can the polygraph be considered a useful tool? The Polygraph and Lie Detection puts the polygraph itself to the test, reviewing and analyzing data about its use in criminal investigation, employment screening, and counter-intelligence. The book looks at: The theory of how the polygraph works and evidence about how deceptivenessâ€"and other psychological conditionsâ€"affect the physiological responses that the polygraph measures. Empirical evidence on the performance of the polygraph and the success of subjects' countermeasures. The actual use of the polygraph in the arena of national security, including its role in deterring threats to security. The book addresses the difficulties of measuring polygraph accuracy, the usefulness of the technique for aiding interrogation and for deterrence, and includes potential alternativesâ€"such as voice-stress analysis and brain measurement techniques.
Download or read book Pesticides Documentation Bulletin written by and published by . This book was released on 1968 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Detection Theory written by Neil A. Macmillan and published by Psychology Press. This book was released on 2004-09-22 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: Detection Theory is an introduction to one of the most important tools for analysis of data where choices must be made and performance is not perfect. Originally developed for evaluation of electronic detection, detection theory was adopted by psychologists as a way to understand sensory decision making, then embraced by students of human memory. It has since been utilized in areas as diverse as animal behavior and X-ray diagnosis. This book covers the basic principles of detection theory, with separate initial chapters on measuring detection and evaluating decision criteria. Some other features include: *complete tools for application, including flowcharts, tables, pointers, and software; *student-friendly language; *complete coverage of content area, including both one-dimensional and multidimensional models; *separate, systematic coverage of sensitivity and response bias measurement; *integrated treatment of threshold and nonparametric approaches; *an organized, tutorial level introduction to multidimensional detection theory; *popular discrimination paradigms presented as applications of multidimensional detection theory; and *a new chapter on ideal observers and an updated chapter on adaptive threshold measurement. This up-to-date summary of signal detection theory is both a self-contained reference work for users and a readable text for graduate students and other researchers learning the material either in courses or on their own.
Download or read book Radiation Detection written by Douglas McGregor and published by CRC Press. This book was released on 2020-08-19 with total page 1286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiation Detection: Concepts, Methods, and Devices provides a modern overview of radiation detection devices and radiation measurement methods. The book topics have been selected on the basis of the authors’ many years of experience designing radiation detectors and teaching radiation detection and measurement in a classroom environment. This book is designed to give the reader more than a glimpse at radiation detection devices and a few packaged equations. Rather it seeks to provide an understanding that allows the reader to choose the appropriate detection technology for a particular application, to design detectors, and to competently perform radiation measurements. The authors describe assumptions used to derive frequently encountered equations used in radiation detection and measurement, thereby providing insight when and when not to apply the many approaches used in different aspects of radiation detection. Detailed in many of the chapters are specific aspects of radiation detectors, including comprehensive reviews of the historical development and current state of each topic. Such a review necessarily entails citations to many of the important discoveries, providing a resource to find quickly additional and more detailed information. This book generally has five main themes: Physics and Electrostatics needed to Design Radiation Detectors Properties and Design of Common Radiation Detectors Description and Modeling of the Different Types of Radiation Detectors Radiation Measurements and Subsequent Analysis Introductory Electronics Used for Radiation Detectors Topics covered include atomic and nuclear physics, radiation interactions, sources of radiation, and background radiation. Detector operation is addressed with chapters on radiation counting statistics, radiation source and detector effects, electrostatics for signal generation, solid-state and semiconductor physics, background radiations, and radiation counting and spectroscopy. Detectors for gamma-rays, charged-particles, and neutrons are detailed in chapters on gas-filled, scintillator, semiconductor, thermoluminescence and optically stimulated luminescence, photographic film, and a variety of other detection devices.
Download or read book Sequence Evolution Function written by Eugene V. Koonin and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.
Download or read book Principles Methods and General Applications written by Gunter Zweig and published by Elsevier. This book was released on 2013-09-11 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analytical Methods for Pesticides, Plant Growth Regulators, and Food Additives, Volume 1: Principles, Methods, and General Applications provides information on analytical techniques useful for the determination of pesticides, plant growth regulators, and food additives. The book discusses the potential hazard of minute residues to human and animal health; the principles of formulation and residue analyses; and the principles of food additive analysis. The text also describes the extraction and clean-up procedures; and the principles of toxicological testing methods. The methods for pesticide analysis in meat products; and the formulation and residue analysis in government laboratories are also considered. The book further tackles other methods, such as spectrophotometric methods, chromatography, isotope methods, enzymatic methods; and bioassay. Agricultural toxicologists and people studying pesticides and food additives will find the text invaluable.
Download or read book Studies written by Rockefeller Institute for Medical Research and published by . This book was released on 1907 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Journal of Experimental Medicine written by and published by . This book was released on 1906 with total page 934 pages. Available in PDF, EPUB and Kindle. Book excerpt:
