Download or read book Drug Safety Data How to Analyze Summarize and Interpret to Determine Risk written by Michael J. Klepper and published by Jones & Bartlett Publishers. This book was released on 2010-09-15 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk was selected for The First Clinical Research Bookshelf - Essential reading for clinical research professionals by the Journal of Clinical Research Best Practices. Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk provides drug safety/pharmacovogilance professionals, pharmaceutical and clinical research scientists, statisticians, programmers, medical writers, and technicians with an accessible, practical framework for the analysis, summary and interpretation of drug safety data. The only guide of its kind, Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk is an invaluable reference for pre- and post-marketing risk assessment. With decades of pharmaceutical research and drug safety expertise, authors Dr. Klepper and Dr. Cobert discuss how quality planning, safety training, and data standardization result in significant cost, time, and resource savings. Through illustrative, step-by-step instruction, Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk is the definitive guide to drug safety data analysis and reporting. Key features include: * Step-by-step instruction on how to analyze, summarize and interpret safety data for mandatory governmental safety reports * Pragmatic tips...and mistakes to avoid * Simple explanations of what safety data are collected, and what the data mean * Practical approaches to determining a drug effect and understanding its clinical significance * Guidance for determining risk throughout the lifecycle of a drug, biologic or nutraceutical * Examples of user-friendly data displays that enhance safety signal identification * Ways to improve data quality and reduce the time, resources and costs involved in mandatory safety reporting * Relevant material for the required training of drug safety/pharmacovigilance professionals * SPECIAL FEATURE: Actual examples of an Integrated Analysis of Safety (IAS) -used in the preparation of the Integrated Summary of Safety (ISS) and the Summary of Clinical Safety (SCS) reports -, and the Periodic Safety Update Report (PSUR)

Download or read book Optimization of Pharmaceutical R d Programs and Portfolios written by Zoran Antonijevic and published by . This book was released on 2014-10-31 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Diffusion in Nanoporous Materials 2 Volumes written by Jörg Kärger and published by John Wiley & Sons. This book was released on 2012-10-29 with total page 932 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atoms and molecules in all states of matter are subject to continuous irregular movement. This process, referred to as diffusion, is among the most general and basic phenomena in nature and determines the performance of many technological processes. This book provides an introduction to the fascinating world of diffusion in microporous solids. Jointly written by three well-known researchers in this field, it presents a coherent treatise, rather than a compilation of separate review articles, covering the theoretical fundamentals, molecular modeling, experimental observation and technical applications. Based on the book Diffusion in Zeolites and other Microporous Solids, originally published in 1992, it illustrates the remarkable speed with which this field has developed since that time. Specific topics include: new families of nanoporous materials, micro-imaging and single-particle tracking, direct monitoring of transient profiles by interference microscopy, single-file diffusion and new approaches to molecular modeling.

Download or read book Eat Drink Heal written by Gregory Buford and published by Createspace Independent Publishing Platform. This book was released on 2016-11-04 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Board Certified Plastic Surgeon, Dr. Gregory A. Buford realized early on that how you eat plays a major role in how you heal. Having spoken on this topic in a number of major medical conferences across the country, he makes this important information accessible to patients in his newest work. "Eat Drink Heal: The Art and Science of Surgical Nutrition". Dr. Buford discusses not only why proper nutrition is important but also how to achieve optimal healing through proper planning before you ever even go to surgery. This information is meant for anyone scheduled for elective or non-elective surgery and may quite simply mean the difference between a smooth recover and one that is not.

Download or read book Aesthetic Plastic Surgery E Book written by Sherrell J Aston and published by Elsevier Health Sciences. This book was released on 2012-10-14 with total page 973 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aesthetic Plastic Surgery - edited by Sherrell J. Aston, MD, Douglas S. Steinbrech, MD and Jennifer L. Walden, MD - brings you the masterful expertise you need to achieve breathtaking outcomes for every cosmetic surgery procedure, including MACS lift, endoscopic mid and lower face rejuvenation, lid/cheek blending - the tear trough, cohesive gel breast augmentation, lipoabdominoplasty, and many more. A "who's who" of international authorities in plastic surgery explain their signature techniques, giving you all the know-how you need deliver the exceptional results your patients demand. Operative videos on DVD let you observe these techniques being performed in real time; and Expert Consult online access enables you to reference the text, download the images, and watch the videos from any computer. Coverage of hot topics includes MACS lift, endoscopic mid and lower face rejuvenation, lid/cheek blending - the tear trough, the newest rhinoplasty techniques, cohesive gel breast augmentation, fat grafting techniques, details of the latest injectables and fillers, and many other highly sought-after procedures. Operative videos - on DVD and online - let you see how leading experts perform more than 50 important techniques, including extended SMAS face lift, traditional inverted-T breast augmentation, and lipoabdominoplasty. Nearly 1600 full-color photographs and illustrations demonstrate what to look for and what results you will achieve. A consistent, extremely user-friendly organization guides you through history, evaluation, anatomy, technical steps, post-operative care, complications, and pearls and pitfalls for each procedure - giving you all the advice you need to make informed, effective decisions and avoid complications and disappointing results. Expert Consult online access allows you to reference the complete contents, perform rapid searches, download the images, and watch the operative videos from any computer. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should online access to the web site be discontinued.

Download or read book Toward Speaking Excellence written by Dean Papajohn and published by University of Michigan Press ELT. This book was released on 2005 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of Toward Speaking Excellence addresses the recent changes to the Test of Spoken English (TSE(R)). The text introduces readers to the format of the new TSE(R), typical questions, and scoring criteria. The second edition of Toward Speaking Excellence includes actual student responses that are used or modified to highlight specific characteristics of effective communication. Two complete sample TSE(R)-like tests are included for further practice. Also provided are practice with some of the skills that, while no longer tested on the TSE(R), are key to sounding more native-like and fluent. Toward Speaking Excellence may be used as an individual study tool or as a course text. While the material is directed toward the TSE(R) and SPEAK(R) tests, the communication strategies presented will prepare students for other types of oral exams (including the TAST(R), interviews, and performance tests. Toward Speaking Excellence is a course book but may also be used for individual test-preparation/self-study. Dean Papajohn is a Specialist in Education at the Center for Teaching Excellence, University of Illinois, Urbana-Champaign..

Download or read book Beauty and the Business written by Gregory A Buford and published by Morgan James Publishing. This book was released on 2010-01-30 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides information on developing a successful aesthetic medicine practice, covering such topics as branding, defining a market, promotion, marketing, image and reputation, and chossing staff.

Download or read book Atlas at War written by Michael Vassallo and published by Naval Institute Press. This book was released on 2020-06-17 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atlas at War! collects fifty hard-hitting stories from Atlas Comics, the company that became Marvel Comics and published more war titles than anyone in the industry between the years 1951 and 1960. Comics historian Dr. Michael J. Vassallo has chosen the best of the best, many of which are coming back into print for the first time, from sixteen different Atlas war titles and featuring the artwork of twenty different artists--giants of the genre, including Russ Heath, John Severin, Bernie Krigstein, Joe Maneely, Jerry Robinson, Steve Ditko, and Jack Kirby. Each page has been meticulously restored from its first printing by comic art restorer Allan Harvey. Atlas at War! covers the brutal pre-code period where graphic depictions of war action were rendered by artists who were World War II veterans themselves, as well as the post-code period, where code restrictions forced creators to tell stories without graphic violence but produced some of the most beautiful comic art of the genre. In addition to the artists, stories cover all aspects of war--from famous campaigns, weaponry, and personal soldier stories to political topics, Nazi atrocities, and even one story tinged with pre-code horror! Often overlooked in favor of its competitors, Atlas at War! will finally show that Atlas' war titles were second to no one.

Download or read book The Compleat Victory written by Kevin J. Weddle and published by Oxford University Press. This book was released on 2021-01-15 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late summer and fall of 1777, after two years of indecisive fighting on both sides, the outcome of the American War of Independence hung in the balance. Having successfully expelled the Americans from Canada in 1776, the British were determined to end the rebellion the following year and devised what they believed a war-winning strategy, sending General John Burgoyne south to rout the Americans and take Albany. When British forces captured Fort Ticonderoga with unexpected ease in July of 1777, it looked as if it was a matter of time before they would break the rebellion in the North. Less than three and a half months later, however, a combination of the Continental Army and Militia forces, commanded by Major General Horatio Gates and inspired by the heroics of Benedict Arnold, forced Burgoyne to surrender his entire army. The American victory stunned the world and changed the course of the war. Kevin J. Weddle offers the most authoritative history of the Battle of Saratoga to date, explaining with verve and clarity why events unfolded the way they did. In the end, British plans were undone by a combination of distance, geography, logistics, and an underestimation of American leadership and fighting ability. Taking Ticonderoga had misled Burgoyne and his army into thinking victory was assured. Saratoga, which began as a British foraging expedition, turned into a rout. The outcome forced the British to rethink their strategy, inflamed public opinion in England against the war, boosted Patriot morale, and, perhaps most critical of all, led directly to the Franco-American alliance. Weddle unravels the web of contingencies and the play of personalities that ultimately led to what one American general called "the Compleat Victory."

Download or read book The Snatch Racket written by Carolyn Cox and published by U of Nebraska Press. This book was released on 2021-03 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Snatch Racket will take the reader behind the scenes of kidnapping crimes that terrified the American public in the 1930s.

Download or read book R Markdown written by Yihui Xie and published by CRC Press. This book was released on 2018-07-27 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: R Markdown: The Definitive Guide is the first official book authored by the core R Markdown developers that provides a comprehensive and accurate reference to the R Markdown ecosystem. With R Markdown, you can easily create reproducible data analysis reports, presentations, dashboards, interactive applications, books, dissertations, websites, and journal articles, while enjoying the simplicity of Markdown and the great power of R and other languages. In this book, you will learn Basics: Syntax of Markdown and R code chunks, how to generate figures and tables, and how to use other computing languages Built-in output formats of R Markdown: PDF/HTML/Word/RTF/Markdown documents and ioslides/Slidy/Beamer/PowerPoint presentations Extensions and applications: Dashboards, Tufte handouts, xaringan/reveal.js presentations, websites, books, journal articles, and interactive tutorials Advanced topics: Parameterized reports, HTML widgets, document templates, custom output formats, and Shiny documents. Yihui Xie is a software engineer at RStudio. He has authored and co-authored several R packages, including knitr, rmarkdown, bookdown, blogdown, shiny, xaringan, and animation. He has published three other books, Dynamic Documents with R and knitr, bookdown: Authoring Books and Technical Documents with R Markdown, and blogdown: Creating Websites with R Markdown. J.J. Allaire is the founder of RStudio and the creator of the RStudio IDE. He is an author of several packages in the R Markdown ecosystem including rmarkdown, flexdashboard, learnr, and radix. Garrett Grolemund is the co-author of R for Data Science and author of Hands-On Programming with R. He wrote the lubridate R package and works for RStudio as an advocate who trains engineers to do data science with R and the Tidyverse.

Download or read book bookdown written by Yihui Xie and published by CRC Press. This book was released on 2016-12-12 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: bookdown: Authoring Books and Technical Documents with R Markdown presents a much easier way to write books and technical publications than traditional tools such as LaTeX and Word. The bookdown package inherits the simplicity of syntax and flexibility for data analysis from R Markdown, and extends R Markdown for technical writing, so that you can make better use of document elements such as figures, tables, equations, theorems, citations, and references. Similar to LaTeX, you can number and cross-reference these elements with bookdown. Your document can even include live examples so readers can interact with them while reading the book. The book can be rendered to multiple output formats, including LaTeX/PDF, HTML, EPUB, and Word, thus making it easy to put your documents online. The style and theme of these output formats can be customized. We used books and R primarily for examples in this book, but bookdown is not only for books or R. Most features introduced in this book also apply to other types of publications: journal papers, reports, dissertations, course handouts, study notes, and even novels. You do not have to use R, either. Other choices of computing languages include Python, C, C++, SQL, Bash, Stan, JavaScript, and so on, although R is best supported. You can also leave out computing, for example, to write a fiction. This book itself is an example of publishing with bookdown and R Markdown, and its source is fully available on GitHub.

Download or read book Problems in Periorbital Surgery written by Foad Nahai and published by Thieme. This book was released on 2018-12-07 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: Problems in Periorbital Surgery: A Repair Manual The field of periorbital surgery has expanded exponentially in recent decades. With its rise in popularity, however, comes a rise in complications. Finally there is a comprehensive guide to repairing the problems encountered in periorbital surgery, compiled by masters in the art of periorbital surgery! This unique resource for plastic, facial plastic and oculoplastic surgeons offers several key features: A thorough discussion on the history and examination for the evaluation of the eyelid Stepwise guidance for correcting a range of complications in periorbital surgery, including infection and bleeding, blindness and motility disorders, specific upper and lower eyelid problems including lid retraction, chemosis, and adverse results from fillers and resurfacing Several chapters, presenting different approaches, devoted to the challenging problem of lid retraction and its multifactorial etiology A case-report format that provides detailed discussions of all possible complications Expert techniques from renowned surgeons providing multiple perspectives on the same problems More than 300 color photographs and beautifully detailed surgical illustrations Multiple video clips showing details of eyelid evaluation and corrective techniques Both print and electronic formats for easy access everywhere To meet the ever-increasing patient demand for these youth-restoring procedures, all surgeons undertaking eyelid surgery and committed to prevent and treat complications of periorbital surgery should have this resource in their collection!

Download or read book Dallas Rhinoplasty written by Rod J. Rohrich and published by CRC Press. This book was released on 2014-03-04 with total page 1636 pages. Available in PDF, EPUB and Kindle. Book excerpt: A renowned rhinoplasty reference, this two-volume set presents the work of recognized pioneers in the field who provide comprehensive coverage of primary and secondary rhinoplasty. From basic fundamentals and anatomy to the latest refinements and advances in technique, the book includes comprehensive case analyses to facilitate clinical decision making—supplying rhinoplasty surgeons with all the tools needed for achieving superb results. Featuring 18 new chapters and numerous color images, this third edition is supplemented with DVDs containing videos of operative procedures. Dallas Rhinoplasty, Nasal Surgery by the Masters is now available with a bundled e-book for the first time. Readers can download photos, videos, text, and much more. Presents the work of recognized pioneers in the field Provides comprehensive coverage of primary and secondary rhinoplasty Covers basic fundamentals and anatomy Presents the latest refinements and advances in technique for safer, more consistent results Includes new innovations for achieving a smooth dorsum, avoiding alar notching, and improving tip refinement Supplies comprehensive case analyses to facilitate clinical decision making Features 18 new chapters with numerous color images and 4 DVDs with 14 full-length operative videos * eBook version is included with purchase of the print book.

Download or read book Practical Dermoscopy written by Jie Liu and published by Springer Nature. This book was released on 2022-08-10 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide readers with practical information on the procedure of streamline skin disease recognition with the use of dermoscopy. The first three chapters are mainly focused on the basic knowledge of dermoscopy, such as its history, how it works, the terminology. In the following chapters, the clinical photographs, dermoscopic images and histopathologic images of benign melanocytic neoplasms, malignant melanoma, basal cell carcinoma, seborrheic keratosis and related diseases, vascular diseases, squamous cell neoplasms and other neoplasms are presented in a case-based format. The clinical characteristics are introduced briefly, and the dermoscopic features are highlighted with a number of pictures. The chapter 12 to chapter 14 introduce the dermoscopic appearance of inflammatory skin diseases, infectious and parasitic skin diseases, hair and nail diseases, respectively, which is the extended application of dermoscopy. Last but not least, the development and future of articifial intellegence assisted diagnosis based on dermoscopic images is introduced. Written by dermatologists who have been involved in dermoscopic diagnosis for a long time, this case-based book will be a valuable reference for dermatologists and those who are interested in related field.

Download or read book EnvStats written by Steven P. Millard and published by Springer Science & Business Media. This book was released on 2013-10-16 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes EnvStats, a new comprehensive R package for environmental statistics and the successor to the S-PLUS module EnvironmentalStats for S-PLUS (first released in 1997). EnvStats and R provide an open-source set of powerful functions for performing graphical and statistical analyses of environmental data, bringing major environmental statistical methods found in the literature and regulatory guidance documents into one statistical package, along with an extensive hypertext help system that explains what these methods do, how to use these methods, and where to find them in the environmental statistics literature. EnvStats also includes numerous built-in data sets from regulatory guidance documents and the environmental statistics literature. This book shows how to use EnvStats and R to easily: * graphically display environmental data * plot probability distributions * estimate distribution parameters and construct confidence intervals on the original scale for commonly used distributions such as the lognormal and gamma, as well as do this nonparametrically * estimate and construct confidence intervals for distribution percentiles or do this nonparametrically (e.g., to compare to an environmental protection standard) * perform and plot the results of goodness-of-fit tests * compute optimal Box-Cox data transformations * compute prediction limits and simultaneous prediction limits (e.g., to assess compliance at multiple sites for multiple constituents) * perform nonparametric estimation and test for seasonal trend (even in the presence of correlated observations) * perform power and sample size computations and create companion plots for sampling designs based on confidence intervals, hypothesis tests, prediction intervals, and tolerance intervals * deal with non-detect (censored) data * perform Monte Carlo simulation and probabilistic risk assessment * reproduce specific examples in EPA guidance documents EnvStats combined with other R packages (e.g., for spatial analysis) provides the environmental scientist, statistician, researcher, and technician with tools to “get the job done!”

Download or read book Oversight of the Department of Justice written by United States. Congress and published by Createspace Independent Publishing Platform. This book was released on 2017-09-06 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oversight of the Department of Justice : hearing before the Committee on the Judiciary, House of Representatives, One Hundred Fourteenth Congress, second session, July 12, 2016.