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Book The Prevention and Treatment of Missing Data in Clinical Trials

Download or read book The Prevention and Treatment of Missing Data in Clinical Trials written by National Research Council and published by National Academies Press. This book was released on 2010-12-21 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.

Book Prevention of Bullying in Schools  Colleges  and Universities

Download or read book Prevention of Bullying in Schools Colleges and Universities written by American Educational Research Association (AERA) and published by . This book was released on 2013-04-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The peer-reviewed report presented as a series of 11 briefs, addresses legislative, policy, and procedural matters with pragmatic and practical strategies for prevention of bullying.

Book New Developments in Dementia Prevention Research

Download or read book New Developments in Dementia Prevention Research written by Kate Irving and published by Routledge. This book was released on 2018-11-02 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Developments in Dementia Prevention Research addresses a dearth of knowledge about dementia prevention and shows the importance of considering the broader social impact of certain risk factors, including the role we each play in our own cognitive health throughout the lifespan. The book draws on primary and secondary research in order to investigate the relationship between modifiable factors, including vascular and psychosocial risks, that may affect the incidence of dementia. Bringing together world-leading expertise from applied science, medicine, psychology, health promotion, epidemiology, health economics, social policy and primary care, the book compares and contrasts scientific and service developments across a range of settings. Each chapter presents these themes in a way that will ensure best practice and further research in the field of dementia prevention is disseminated successfully throughout the world. Perhaps most importantly, chapters also question what type of social responsibility we are prepared to embrace in order to address the challenges inherent in dementia prevalence. New Developments in Dementia Prevention Research includes contributions from leading authorities in brain health and dementia prevention and provides an essential contribution to the discourse on dementia prevention. It will be of great interest to academics, researchers and postgraduate students engaged in the study of the psychological and social aspects of aging and dementia.

Book Reducing Risks for Mental Disorders

Download or read book Reducing Risks for Mental Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 1994-01-01 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding of how to reduce risk factors for mental disorders has expanded remarkably as a result of recent scientific advances. This study, mandated by Congress, reviews those advances in the context of current research and provides a targeted definition of prevention and a conceptual framework that emphasizes risk reduction. Highlighting opportunities for and barriers to interventions, the book draws on successful models for the prevention of cardiovascular disease, injuries, and smoking. In addition, it reviews the risk factors associated with Alzheimer's disease, schizophrenia, alcohol abuse and dependence, depressive disorders, and conduct disorders and evaluates current illustrative prevention programs. The models and examination provide a framework for the design, application, and evaluation of interventions intended to prevent mental disorders and the transfer of knowledge about prevention from research to clinical practice. The book presents a focused research agenda, with recommendations on how to develop effective intervention programs, create a cadre of prevention researchers, and improve coordination among federal agencies.

Book Relieving Pain in America

    Book Details:
  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release : 2011-10-26
  • ISBN : 030921484X
  • Pages : 383 pages

Download or read book Relieving Pain in America written by Institute of Medicine and published by National Academies Press. This book was released on 2011-10-26 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic pain costs the nation up to $635 billion each year in medical treatment and lost productivity. The 2010 Patient Protection and Affordable Care Act required the Department of Health and Human Services (HHS) to enlist the Institute of Medicine (IOM) in examining pain as a public health problem. In this report, the IOM offers a blueprint for action in transforming prevention, care, education, and research, with the goal of providing relief for people with pain in America. To reach the vast multitude of people with various types of pain, the nation must adopt a population-level prevention and management strategy. The IOM recommends that HHS develop a comprehensive plan with specific goals, actions, and timeframes. Better data are needed to help shape efforts, especially on the groups of people currently underdiagnosed and undertreated, and the IOM encourages federal and state agencies and private organizations to accelerate the collection of data on pain incidence, prevalence, and treatments. Because pain varies from patient to patient, healthcare providers should increasingly aim at tailoring pain care to each person's experience, and self-management of pain should be promoted. In addition, because there are major gaps in knowledge about pain across health care and society alike, the IOM recommends that federal agencies and other stakeholders redesign education programs to bridge these gaps. Pain is a major driver for visits to physicians, a major reason for taking medications, a major cause of disability, and a key factor in quality of life and productivity. Given the burden of pain in human lives, dollars, and social consequences, relieving pain should be a national priority.

Book A Guide to Conducting Prevention Research in the Community

Download or read book A Guide to Conducting Prevention Research in the Community written by James G Kelly and published by Routledge. This book was released on 2014-02-04 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This provocative and useful volume is a step-by-step guide to assist professionals in implementing valid and useful community research and creating preventive interventions that have positive and lasting effects on the development of the community. The authors--including James G. Kelly, one of the fathers of prevention--offer valuable suggestions for developing community processes to assist the prevention researcher and the community in designing research that is embedded in the community. Experts focus on the topics that can help establish and sustain effective long-term working relationships with community members. Numerous examples illustrate how the collaborative working relationship can create the variety of resources that are needed to eventually implement policy changes stimulated by the research and help to sustain the impact of the research findings after the research has been completed. This exciting book illustrates how community research related to the prevention of mental illness and the promotion of mental health can be scientific and objective, as well as a positive collaboration between the research staff and community members. Focus upon community needs Emphasize educational activities to support the prevention research Identify points of policy impact before the research begins Enhance the development of social networks and social support systems for the development of competencies Provide criteria for the selection of systemic variables for the research Include reference to the multiple levels of a community which may affect the research topic Specify ways in which participants can identify and own the research topic Outline criteria for assessing the side effects of the prevention research In order to better understand the needs, values, commitments, and resources of the community in which he or she is working, the researcher is encouraged to select research topics derived from underlying community needs, educated the public about prevention, identify points of policy impact, and determine the informal social networks that enhance the development of social competencies in the community. The benefits of the collaborative relationship between prevention researchers and the community are strongly emphasized. A Guide to Conducting Prevention Research in the Community aims to guide citizens and professionals in implementing valid and useful community research and create preventive interventions that have positive and lasting effects on the development of the community.

Book Fulfilling the Potential of Cancer Prevention and Early Detection

Download or read book Fulfilling the Potential of Cancer Prevention and Early Detection written by National Research Council and published by National Academies Press. This book was released on 2003-05-07 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer ranks second only to heart disease as a leading cause of death in the United States, making it a tremendous burden in years of life lost, patient suffering, and economic costs. Fulfilling the Potential for Cancer Prevention and Early Detection reviews the proof that we can dramatically reduce cancer rates. The National Cancer Policy Board, part of the Institute of Medicine, outlines a national strategy to realize the promise of cancer prevention and early detection, including specific and wide-ranging recommendations. Offering a wealth of information and directly addressing major controversies, the book includes: A detailed look at how significantly cancer could be reduced through lifestyle changes, evaluating approaches used to alter eating, smoking, and exercise habits. An analysis of the intuitive notion that screening for cancer leads to improved health outcomes, including a discussion of screening methods, potential risks, and current recommendations. An examination of cancer prevention and control opportunities in primary health care delivery settings, including a review of interventions aimed at improving provider performance. Reviews of professional education and training programs, research trends and opportunities, and federal programs that support cancer prevention and early detection. This in-depth volume will be of interest to policy analysts, cancer and public health specialists, health care administrators and providers, researchers, insurers, medical journalists, and patient advocates.

Book The Violence Project

Download or read book The Violence Project written by Jillian Peterson and published by Abrams. This book was released on 2021-09-07 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Groundbreaking." ―Rachel Louise Snyder, bestselling author of No Visible Bruises An examination of the phenomenon of mass shootings in America and an urgent call to implement evidence-based strategies to stop these tragedies Winner of the 2022 Minnesota Book Award Using data from the writers’ groundbreaking research on mass shooters, including first-person accounts from the perpetrators themselves, The Violence Project charts new pathways to prevention and innovative ways to stop the social contagion of violence. Frustrated by reactionary policy conversations that never seemed to convert into meaningful action, special investigator and psychologist Jill Peterson and sociologist James Densley built The Violence Project, the first comprehensive database of mass shooters. Their goal was to establish the root causes of mass shootings and figure out how to stop them by examining hundreds of data points in the life histories of more than 170 mass shooters—from their childhood and adolescence to their mental health and motives. They’ve also interviewed the living perpetrators of mass shootings and people who knew them, shooting survivors, victims’ families, first responders, and leading experts to gain a comprehensive firsthand understanding of the real stories behind them, rather than the sensationalized media narratives that too often prevail. For the first time, instead of offering thoughts and prayers for the victims of these crimes, Peterson and Densley share their data-driven solutions for exactly what we must do, at the individual level, in our communities, and as a country, to put an end to these tragedies that have defined our modern era.

Book The Cambridge Handbook of International Prevention Science

Download or read book The Cambridge Handbook of International Prevention Science written by Moshe Israelashvili and published by . This book was released on 2017 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Cambridge Handbook of International Prevention Science offers a comprehensive global overview on prevention science with the most up-to-date research from around the world. Over 100 scholars from 27 different countries (including Australia, Bhutan, Botswana, India, Israel, Mexico, Singapore, South Korea, Spain and Thailand) contributed to this volume, which covers a wide range of topics important to prevention science. It includes major sections on the foundations of prevention as well as examples of new initiatives in the field, detailing current prevention efforts across the five continents. A unique and innovative volume, The Cambridge Handbook of International Prevention Science is a valuable resource for established scholars, early professionals, students, practitioners and policy-makers"--

Book Defining Prevention Science

Download or read book Defining Prevention Science written by Zili Sloboda and published by Springer. This book was released on 2014-07-08 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whoever coined the adage "an ounce of prevention is worth a pound of cure" could not have known how important this adage would become. The challenge of altering the health trajectories of poor lifestyle decisions for such behaviors as smoking, drinking and using illicit drugs, violence, dropping out of school, engagement in risky sexual behaviors and crime through prevention research has led to a new discipline, prevention science. Defining Prevention Science covers this emerging field of science: its goals, its conceptual and theoretical foundations, its methods and especially its utility. Not content to simply differentiate the field from its close allies: epidemiology, psychology, neuroscience, sociology, economics, the text explains how these many disciplines enhance each other at both research and intervention levels and how prevention science draws on these biological, behavioral and social sciences to create an innovative knowledge base that has provided cost-effective, evidence-based prevention interventions and policies. To this end, familiar developmental benchmarks are recast in prevention/health promotion context, from the crucial importance of adolescence in encountering and deterring high-risk behaviors to the risks and resiliencies of single-mother families. An international group of contributors offers current findings, up-to-date methods for effective evidence-based interventions and improvements in research technologies in these key areas: Physical, cognitive and emotional vulnerability across the life course. The roles of developmental influences in prevention. Intervention development, delivery and implementation. Bringing the intervention approach to research design. New directions in analytic methods. Cost analysis and policy implications. Advances in Prevention Science: Defining Prevention Science aims to inspire further refinements in the field and encourage communication among researchers in its own and related disciplines, including public health, epidemiology, psychology, and criminology. This is the first volume in the series, Advances in Prevention Science, that provides the framework for other volume that will focus on such issues as: Prevention Science in School Settings: Complex Relationships and Processes; Preventing Crime and Violence and The Prevention of Substance Use.

Book Intervention Research

Download or read book Intervention Research written by Nyanda McBride and published by Springer. This book was released on 2016-08-01 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a step-by-step guide to intervention research, including the methods and techniques that researchers, higher degree research students and others can use when pursuing intervention research in schools and other settings. Guided by the Intervention Research Framework, it also provides practical information on linking a program developed using a comprehensive, evidence-based approach, to research and evaluation processes. The handbook also illustrates how to select an appropriate research sample for research; how to develop valid and reliable instruments for measuring change, including how to devise appropriate measures for assessing behavioural change; how to recruit and negotiate with schools (and other settings) for research involving young people; how to measure and incorporate measures of fidelity of implementation to understand dose response and behavior change; and how to optimize data collection and dissemination. The development and longitudinal assessment of the multi award-winning School Health and Alcohol Harm Reduction Project (SHAHRP) – the first alcohol harm reduction study to assess the impact of a school-based classroom intervention on alcohol use, alcohol-related behaviors and alcohol-related harm using a harm reduction paradigm – provides a practical example of the intervention research processes described in this handbook.

Book Designing Evidence Based Public Health and Prevention Programs

Download or read book Designing Evidence Based Public Health and Prevention Programs written by Mark E. Feinberg and published by Routledge. This book was released on 2020-11-29 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Demonstrating that public health and prevention program development is as much art as science, this book brings together expert program developers to offer practical guidance and principles in developing effective behavior-change curricula. Feinberg and the team of experienced contributors cover evidence-based programs addressing a range of physical, mental, and behavioral health problems, including ones targeting families, specific populations, and developmental stages. The contributors describe their own professional journeys and decisions in creating, refining, testing, and disseminating a range of programs and strategies. Readers will learn about selecting change-promoting targets based on existing research; developing and creating effective and engaging content; considering implementation and dissemination contexts in the development process; and revising, refining, expanding, abbreviating, and adapting a curriculum across multiple iterations. Designing Evidence-Based Public Health and Prevention Programs is essential reading for prevention scientists, prevention practitioners, and program developers in community agencies. It also provides a unique resource for graduate students and postgraduates in family sciences, developmental psychology, clinical psychology, social work, education, nursing, public health, and counselling.

Book Alcohol Problems Among Adolescents

Download or read book Alcohol Problems Among Adolescents written by Gayle M. Boyd and published by Psychology Press. This book was released on 2013-05-13 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol misuse presents a major risk for health and well-being throughout the life-span, but youth have a special vulnerability. Alcohol is the most widely used drug by adolescents. For some, this may be one or two isolated occasions of youthful experimentation; for others, the use becomes excessive, placing them in danger of immediate adverse consequences such as accidental injury and alcohol poisoning, or encouraging other high-risk behavior patterns including unprotected sex. Moreover, a pattern of heavy drinking established in adolescence and young adulthood may continue into an adult pattern of alcohol abuse. Concerned communities and institutions across the nation are tackling the problem of alcohol use and abuse by young people. Research-based knowledge is urgently needed to inform these efforts and to ensure that limited prevention resources are used as effectively as possible. The origins of youthful alcohol use and abuse are found within the complex interplay of individual characteristics, family and peer influences, the larger societal context for alcohol use, environmental conditions, and maturational processes that accompany adolescence. This volume, which began as a special issue of the Journal of Research on Adolescence, contains all of the material from the journal issue plus additional chapters. It helps researchers to meet the tremendous challenge of disentangling the key determinants of risk, and developing effective interventions. Primary sources of influence on youthful alcohol use are described, ranging from individual expectancies about alcohol effects and cognitive decision processes to parenting practices, peer influences, social environments, and economic factors; and a corresponding range of prevention interventions is discussed. This book will serve as a primer to those with an interest in developing and improving effective programs and activities to reduce alcohol-related problems among young people. For those engaged in prevention research, the text will provide useful reviews and current findings that should aid in directing future research activities.

Book Weight Control and Physical Activity

Download or read book Weight Control and Physical Activity written by Harri Vainio and published by IARC. This book was released on 2002 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Avoiding overweight and obesity is the best-established diet-related risk factor for cancer. The proportion of people who are overweight/obese is increasing, and the amount of physical activity is decreasing in most populations, including urban populations in many developing countries. The increasing prevalence of overweight/obesity is presumably due to the increasing availability of highly palatable, high-energy foods, and an increasing sedentary lifestyle due to mechanisation of both workplace and leisure activities. Overweight/obesity and reduced physical activity increases the risk of cancers in various organs. Maintaining a healthy body weight and regular physical activity is the second most important way to prevent cancer, after tobacco control. The suggestions of possible public health actions to tackle these risk factors include the promotion of balanced diets, which are not excessive in energy, and broad education and planning to enable and encourage physical activity during work and leisure. Recommendations and a full discussion of these topics are included in the sixth volume in this series of Handbooks.

Book Adolescent Dating Violence

Download or read book Adolescent Dating Violence written by David Wolfe and published by Academic Press. This book was released on 2018-06-14 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adolescent Dating Violence: Theory, Research, and Prevention summarizes the course, risk/protective factors, consequences and treatment/prevention of adolescent dating violence. Dating violence is defined as physical, sexual, psychological, and cyber behavior meant to cause emotional, physical, or social harm to a current or former intimate partner. The book discusses research design and measurement in the field, focuses on the recent influx of longitudinal studies, and examines prevention and intervention initiatives. Divided into five sections, the book begins by reviewing theory on and consequences of dating violence. Section II discusses risk factors and protective factors such as peer influences, substance use, and past exposure to violence in the family of origin. Section III discusses how social and cultural factors can influence teen dating violence, addressing the prevalence of dating violence among different ethnicities and among LGBTQ teens, and the influence of social media. Section IV discusses recent research priorities including gender inequality, measurement, psychological abuse, and the dual nature of dating violence during adolescence. Section V reviews evidence-based practice for treatment and prevention across various age groups and settings. Encompasses physical, sexual, psychological and cyber violence Introduces theory on dating violence Emphasizes results from longitudinal studies and intervention initiatives Highlights the influence of social media and technology on dating violence Discusses ethnic, gender and other social and cultural differences in prevalence Examines evidence-based practice in treatment and prevention

Book Evidence Based Prevention

Download or read book Evidence Based Prevention written by Katherine Raczynski and published by SAGE Publications. This book was released on 2012-12-20 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: This sixth book in the Prevention Practice Kit provides an introduction to evidence-based prevention in psychology. Counselors, psychologists and mental health workers in schools, government agencies, community settings, and in private practice are increasingly expected to select evidence-based practices and programs, and to document the effectiveness of the care they provide. The book addresses the types of questions that may be most pertinent to counselors, psychologists, and other mental health workers who are engaged in prevention and interested in understanding evidence-based programs, including: What does it mean to for a program to be evidence-based? How should I go about selecting an evidence-based program? How do I know if evidence is trustworthy? How do I gather evidence to evaluate my own prevention program? The book introduces several definitions of evidence-based practice and the common components of these definitions. A broad overview of considerations for evaluating the quality and trustworthiness of prevention research is provided along with a discussion of common features of effective prevention programs. Guidance is provided on identifying evidence-based programs, including detailed descriptions of online registries of prevention programs. The book also provides recommendations for determining the need for a prevention program, selecting and implementing an appropriate program, and evaluating outcomes. Throughout the text, examples from research and practice are used to illustrate important concepts, and learning exercises at the end of each chapter augment comprehension and relevance. This book is part of the Prevention Practice Kit: Action Guides for Mental Health, a collection of eight books each authored by scholars in the specific field of prevention and edited by Dr. Robert K. Conyne and Dr. Arthur M. Horne. The books in the collection conform to the editors′ outline to promote a consistent reading experience. Designed to provide human services practitioners, counselors, psychologists, social workers, instructors, and students with concrete direction for spreading and improving the practice of prevention, the series provides thorough coverage of prevention application including a general overview of prevention, best practices, diversity and cultural relevance, psychoeducational groups, consultation, program development and evaluation, evidence base, and public policy. This book is endorsed by the Prevention Section of the Society of Counseling Psychology of the American Psychological Association. Fifty percent of all royalties are donated to Division 17 of the APA.

Book A Web of Prevention

Download or read book A Web of Prevention written by Brian Rappert and published by Routledge. This book was released on 2012-05-16 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Web of Prevention provides a timely contribution to the current debate about life science research and its implications for security. It is an informative guide for both experts and the public. It is a forward-looking contribution covering both ends of the equation and creates momentum for the current discussion on effective preventive measures and effective control measures. While there are no guarantees for preventing misuse, there are nonetheless crucial steps the world community can take towards the overarching goal of a global network for the life sciences. This book sheds light on concrete steps toward the achievement of this worthy goal. "This book with its collection of essays provides an in-depth analysis of the various mutually reinforcing elements that together create and strengthen a web of prevention - or of assurance - that is vital to ensure that the advances in the life sciences are not misused to cause harm. All those engaged in the life sciences and in policy making in governments around the world should read this book so they can take steps to strengthen the web preventing biological weapons". From the Foreword by Dr Gabriele Kraatz-Wadsack, Chief, Weapons of Mass Destruction Branch, Office for Disarmament Affairs, United Nations. "Since September 11, 2001 in many countries renewed attention has been given to how research in the life sciences might inadvertently or intentionally facilitate the development of biological or chemical weapons. This state-of-the-art volume examines the full extent of the issues and debates. Coverage includes an overview of recent scientific achievements in virology, microbiology, immunology and genetic engineering with a view to asking how they might facilitate the production of weapons of mass destruction by state, sub-state or terrorist organizations. Consideration is given to what we have and haven't learned from the past. Employing both academic analysis and reflections by practitioners, the book examines the security-inspired governance regimes for the life sciences that are under development. Ultimately the authors examine what is required to form a comprehensive and workable web of prevention and highlight the importance of encouraging discussions between scientists, policy makers and others regarding the governance of vital but potentially dangerous research". Dr Graham S. Pearson, Visiting Professor of International Security, University of Bradford, UK and previously Director-General, Chemical and Biological Defence Establishment, UK