Download or read book Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.

Download or read book Childhood Cancer and Functional Impacts Across the Care Continuum written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2021-09-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.

Download or read book Infectious Complications in Cancer Patients written by Valentina Stosor and published by Springer Science & Business Media. This book was released on 2014-04-05 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: While advances in both the treatment of cancer and the management of its complications have led to significant improvement in patient survival, infections remain a significant cause of morbidity and mortality in patients with neo plastic disease. In this patient population, infection risk results from a complex interplay between the host’s underlying immunodeficiencies, local tumor effects and treatment-induced immunosuppression. New chemotherapeutic approaches and antimicrobial prophylaxis and treatment practices continue to shape the spectrum of infections in these patients. Clinicians who treat infections in cancer patients are continually challenged by the emergence of new pathogens and by the increasing antimicrobial resistance of established ones. The aim of this book is to emphasize unique aspects of management of infectious diseases in the cancer patient. With the increasing complexity of this patient population, optimal management requires a multidisciplinary approach and this fact is fully reflected in the contributions, all from recognized authorities in the field. Ultimately, it is hoped that this volume will assist specialists in infectious diseases and haematology/oncology in the diagnosis, management and prevention of infection and optimization of the overall care of patients with malignancies.

Download or read book Antibiotic Resistance written by Anthony R.M. Coates and published by Springer Science & Business Media. This book was released on 2012-10-22 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes antibiotic resistance amongst pathogenic bacteria. It starts with an overview of the erosion of the efficacy of antibiotics by resistance and the decrease in the rate of replacement of redundant compounds. The origins of antibiotic resistance are then described. It is proposed that there is a large bacterial resistome which is a collection of all resistance genes and their precursors in both pathogenic and non-pathogenic bacteria. Ongoing resistance surveillance programs are also discussed, together with the perspective of a clinical microbiologist. The book then turns to specific themes such as the most serious area of resistance in pathogens, namely in Gram-negative organisms. The role of combinations of antibiotics in combating resistance emergence is discussed, particularly in the tuberculosis field, and then the importance of non-multiplying and persistent bacteria which are phenotypically resistant to antibiotics and prolong the duration of therapy of antibiotics which leads to poor compliance and resistance emergence. The role of anti-microbial compounds in textiles is covered, with its potential to exacerbate the spread of resistance. Then, efflux pumps are discussed. The final chapter describes the compounds which are in late stage clinical development, illustrating the paucity of the antibiotic pipeline, especially for Gram-negative bacteria.

Download or read book Preterm Birth written by Institute of Medicine and published by National Academies Press. This book was released on 2007-05-23 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing prevalence of preterm birth in the United States is a complex public health problem that requires multifaceted solutions. Preterm birth is a cluster of problems with a set of overlapping factors of influence. Its causes may include individual-level behavioral and psychosocial factors, sociodemographic and neighborhood characteristics, environmental exposure, medical conditions, infertility treatments, and biological factors. Many of these factors co-occur, particularly in those who are socioeconomically disadvantaged or who are members of racial and ethnic minority groups. While advances in perinatal and neonatal care have improved survival for preterm infants, those infants who do survive have a greater risk than infants born at term for developmental disabilities, health problems, and poor growth. The birth of a preterm infant can also bring considerable emotional and economic costs to families and have implications for public-sector services, such as health insurance, educational, and other social support systems. Preterm Birth assesses the problem with respect to both its causes and outcomes. This book addresses the need for research involving clinical, basic, behavioral, and social science disciplines. By defining and addressing the health and economic consequences of premature birth, this book will be of particular interest to health care professionals, public health officials, policy makers, professional associations and clinical, basic, behavioral, and social science researchers.

Download or read book Infectious Complications of Cancer written by J. Klastersky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the major developments in the therapeutic armamentarium for the treatment of infection, the morbidity and mortality of this complication remains very high in patients with compromised defences. Cancer and its treatment represents a major predisposing condition to a variety of infections. These adverse events are still with us, in spite of much progress in the therapy of infectious disease, since cancer therapy is becoming more aggressive, yet further lowering the host's capacity to cope with infections. Moreover, the pathogens adapt effectively to drugs, and at a pace that might outrun industry's capability to produce new agents. Finally, new pathogens are appearing as a consequence of both selection and severe immunosuppression. Infection is so common among cancer patients that its diagnosis and management represent a daily challenge to all oncologists, who must continually strive to keep abreast of developments in the area. The present comprehensive review of the most crucial and challenging aspects of the infectious complications in cancer patients will help them to do just that.

Download or read book Antifungal Therapy written by Mahmoud Ghannoum and published by CRC Press. This book was released on 2016-04-19 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise one-stop-practical reference for the various physicians dealing with fungal infections, Antifungal Therapy appeals to infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. This book provides a c

Download or read book Infections in Hematology written by Georg Maschmeyer and published by Springer. This book was released on 2014-12-13 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infections are among the most frequent complications in patients with hematological malignancies and in those undergoing high-dose chemotherapy and autologous hematopoietic stem cell transplantation. A profound knowledge on the epidemiology, diagnostic approaches, treatment modalities and prophylactic strategies is essential for the clinical management of these complications in patients who are often severely immunocompromised owing to their underlying diseases and in particular, the intensive myelosuppressive chemo and immunotherapy. This textbook provides a clinically oriented, compact and up-to-date overview on infections in hematology patients and their management. The typical pathogens to be considered in different subgroups of patients are identified and further aspects of the microbiological background are explored. Clinical, imaging, and laboratory-based diagnostic techniques are discussed and therapeutic strategies appropriate to different situations are then presented, with due attention to the pitfalls, toxicities and interactions that can arise during antimicrobial treatment. Strategies to prevent infection are also outlined, encompassing antimicrobial prophylaxis, isolation procedures, hospital hygiene, protective immunization and the use of hematopoietic growth factors.

Download or read book Analysis of Cancer Risks in Populations Near Nuclear Facilities written by National Research Council and published by National Academies Press. This book was released on 2012-06-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.

Download or read book Biomedical Index to PHS supported Research written by and published by . This book was released on 1995 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Pediatric Hematology written by Robert J. Arceci and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric Hematology is a comprehensive and succinct referenced text on the diagnosis and treatment of blood diseases in childhood. It provides a ready source of reference for all the conditions likely to be encountered in day-to-day clinical practice. For each condition, the authors give helpful advice on differential diagnoses and clinical management. This third edition has been extensively updated throughout, in light of recent developments in this rapidly advancing area of medicine. A well established textbook on the diagnosis and treatment of blood disorders in childhood A balanced and cutting edge referenced text on all aspects of diagnosis and treatment Easy to use, practically organized, with essential aspects of biology included within each chapter International editorial and contributor team—representing a wide geographical and chronological range Whether you are an established sub-specialist in pediatric hematology/oncology, a pediatrician, a trainee or nursing specialist, this book will answer all your questions about benign and malignant disorders of the blood in children and young adults.

Download or read book Infections in Pregnancy written by Adel Elkady and published by Cambridge University Press. This book was released on 2019-10-24 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides effective diagnosis and management of infectious diseases in pregnant women in a single comprehensive available resource for busy clinicians.

Download or read book Feigin and Cherry s Textbook of Pediatric Infectious Diseases E Book written by James Cherry and published by Elsevier Health Sciences. This book was released on 2013-10-05 with total page 5004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Feigin and Cherry's Textbook of Pediatric Infectious Diseases helps you put the very latest knowledge to work for your young patients with unparalleled coverage of everything from epidemiology, public health, and preventive medicine through clinical manifestations, diagnosis, treatment, and much more. Ideal for all physicians, whether in an office or hospital setting, Feigin and Cherry’s equips you with trusted answers to your most challenging clinical infectious disease questions. Meet your most difficult clinical challenges in pediatric infectious disease, including today’s more aggressive infectious and resistant strains as well as emerging and re-emerging diseases, with unmatched, comprehensive coverage of immunology, epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. Find the answers you need quickly thanks to an organization both by organ system and by etiologic microorganism, allowing you to easily approach any topic from either direction.

Download or read book Principles and Practice of Pediatric Infectious Diseases E Book written by Marc Fischer and published by Elsevier Health Sciences. This book was released on 2017-05-09 with total page 2253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive in scope, yet concise and easy to manage, Principles and Practice of Pediatric Infectious Diseases, 5th Edition, by Drs. Sarah Long, Charles Prober, and Marc Fischer, is your go-to resource for authoritative information on infectious diseases in children and adolescents. A veritable "who's who" of global authorities provides the practical knowledge you need to understand, diagnose, and manage almost any pediatric infectious disease you may encounter. Features a consistent, easy-access format with high-yield information boxes, highlighted key points, and an abundance of detailed illustrations and at-a-glance tables. Allows quick look-up by clinical presentation, pathogen, or type of host. Includes coverage of the latest vaccine products, recommendations, and effectiveness as well as expanded diagnostics and therapies for autoinflammatory/periodic fever syndromes. Covers emerging viruses such as Zika, Ebola, and EV-D68, as well as infectious risks of immunomodulating drugs and expanding antimicrobial resistance patterns. Discusses expanding antimicrobial resistance patterns and new therapies for viral and fungal infections and resistant bacterial infections. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos (including video updates), glossary, and references from the book on a variety of devices.

Download or read book Aspergillus Fumigatus and Aspergillosis written by Jean-Paul Latgé and published by . This book was released on 2009 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers the latest insights into the fundamental biology and pathogenesis of A. fumigatus. Provides a combined synopsis of both A. fumigatus and its diseases and therapies. Encompasses the most up-to-date knowledge to serve as a resource guide for the next decade of study on this organism and the many diseases it causes. Covers the fundamental biology of A. fumigatus including specific features in genetics, biochemistry, and cell biology that can explain the virulence of this opportunistic pathogen. Discusses the wide range of clinical infection, plus the latest diagnostic and treatment strategies, in specific patient populations.

Download or read book Supportive Care in Pediatric Oncology written by James H. Feusner and published by Springer. This book was released on 2015-02-17 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a thorough and up-to-date discussion of key issues in the supportive care of children with cancer. A variety of frequently encountered situations is covered, including infections, metabolic, cardiopulmonary and neurologic emergencies, tumor lysis syndrome, pain, emesis, mucositis, thrombotic disorders, nutritional problems, hyperleukocytosis and acute abdomen. Throughout the emphasis is firmly on evidenced-based guidance developed from the relevant literature. Information is presented in a manner that will enable readers quickly to locate advice when confronted by a supportive care problem in one of their patients. Helpful algorithms are provided and important “take home points” are highlighted in figures and tables. Supportive Care in Pediatric Oncology will be an invaluable source of assistance for a wide range of health professionals involved in pediatric cancer care.