Download or read book Practical Guidelines in Antiviral Therapy written by G.J. Galasso and published by Elsevier. This book was released on 2002-01-21 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text was developed with the practicing physician in mind, however, it will be of considerable interest to the virologist, pharmacologist, chemist and all scientists interested in antiviral agents. Progress in the field of antiviral development is now moving rapidly and there is hope that one day there will be successful treatment modalities for most viral diseases. This work contains contributions from experts around the world, capturing worldwide practices. An online version providing the current status of antiviral research is planned for the near future.

Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Download or read book Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection written by World Health Organization and published by . This book was released on 2016 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: These guidelines provide guidance on the diagnosis of human immunodeficiency virus (HIV) infection, the use of antiretroviral (ARV) drugs for treating and preventing HIV infection and the care of people living with HIV. They are structured along the continuum of HIV testing, prevention, treatment and care. This edition updates the 2013 consolidated guidelines on the use of antiretroviral drugs following an extensive review of evidence and consultations in mid-2015, shared at the end of 2015, and now published in full in 2016. It is being published in a changing global context for HIV and for health more broadly.

Download or read book Viral Pathogenesis written by Michael G. Katze and published by Academic Press. This book was released on 2015-12-30 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral Pathogenesis: From Basics to Systems Biology, Third Edition, has been thoroughly updated to cover topical advances in the evolving field of viral pathogenesis, while also providing the requisite classic foundational information for which it is recognized. The book provides key coverage of the newfound ability to profile molecular events on a system-wide scale, which has led to a deeper understanding of virus-host interactions, host signaling and molecular-interaction networks, and the role of host genetics in determining disease outcome. In addition, the content has been augmented with short chapters on seminal breakthroughs and profiles of their progenitors, as well as short commentaries on important or controversial issues in the field. Thus, the reader will be given a view of virology research with perspectives on issues such as biomedical ethics, public health policy, and human health. In summary, the third edition will give the student a sense of the exciting new perspectives on viral pathogenesis that have been provided by recent developments in genomics, computation, modeling, and systems biology. - Covers all aspects of viral infection, including viral entry, replication, and release, as well as innate and adaptive immunity and viral pathogenesis - Provides a fresh perspective on the approaches used to understand how viruses cause disease - Features molecular profiling techniques, whole genome sequencing, and innovative computational methods - Highlights the use of contemporary approaches and the insights they provide to the field

Download or read book Antiviral Drug Discovery and Development written by Xinyong Liu and published by Springer Nature. This book was released on 2021-07-13 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes state-of-the-art antiviral drug design and discovery approaches starting from natural products to de novo design, and provides a timely update on recently approved antiviral drugs and compounds in advanced clinical development. Special attention is paid to viral infections with a high impact on the world population or highly relevant from the public health perspective (HIV, hepatitis C, influenza virus, etc.). In these chapters, limitations associated with adverse effects and emergence of drug resistance are discussed in detail. In addition to classical antiviral strategies, chapters will be dedicated to discuss the non-classical drug development strategies to block viral infection, for instance, allosteric inhibitors, covalent antiviral agents, or antiviral compounds targeting protein–protein interactions. Finally, current prospects for producing broad-spectrum antiviral inhibitors will be also addressed. The book is distinctive in providing the most recent update in the rapidly evolving field of antiviral therapeutics. Authoritative reviews are written by international scientists well known for their contributions in their topics of research, which makes this book suitable for researchers not only within the antiviral research community but also attractive to a broad audience in the drug discovery field. This book covers molecular structures and biochemical mechanisms mediating the antiviral effects, while discussing various ligand design strategies, which include traditional medicinal chemistry, computational chemistry, and chemical biology approaches. The book provides a comprehensive review of antiviral drug discovery and development approaches, particularly focusing on current innovations and future trends.

Download or read book Management of Chronic Kidney Disease written by Mustafa Arıcı and published by Springer Nature. This book was released on with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chemotherapy of Viral Infections written by P E. Came and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: " . . . the motto for the therapeutics of the future will have to be de sedibus et causis pharmacorum. " P. EHRLICH, 1909 Exciting events in the basic disciplines of virology, immunology, and pharmacology continue to advance the understanding of the pathogenesis and control of virus diseases. At the same time, the rational development of antiviral agents is attracting, to an increasing extent, the interest of workers in other disciplines. Improvements in technology facilitate the definition of potential target sites for antiviral intervention and unmask new viral and host genes. The outcome is a further steady development of new antiviral agents which approach the "magic bullets" first proposed by PAUL EHRLICH. Remarkable advances in protein synthetic methods that yield polypeptides which inhibit active sites of viral proteins have aided substantially in the basic and clinical study of these antiviral agents. In addition, the extremely rapid progression in recombinant DNA techniques, leading to the synthesis of large quantities of gene products, is also increasing our opportunities at a dashing pace. New information and developing technology facilitate research on the mechanism of action, toxicity, pharmacokinetics, and pharmacodynamics of new agents. The list of clinically effective antiviral agents is expanding and the number of potentially useful compounds is growing rapidly. This book is a combined theoretical text and practical manual which, it is hoped, will be of use to all who have an interest in virus diseases, particularly scientists, physicians and graduate students.

Download or read book Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence written by World Health Organization. Department of Mental Health and Substance Abuse and published by World Health Organization. This book was released on 2009 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: "These guidelines were produced by the World Health Organization (WHO), Department of Mental Health and Substance Abuse, in collaboration with the United Nations Office on Drugs and Crime (UNODC) a Guidelines Development Group of technical experts, and in consultation with the International Narcotics Control Board (INCB) secretariat and other WHO departments. WHO also wishes to acknowledge the financial contribution of UNODC and the Joint United Nations Programme on HIV/AIDS (UNAIDS) to this project. " - p. iv

Download or read book Family Practice Guidelines Fifth Edition written by Jill C. Cash, MSN, APN, FNP-BC and published by Springer Publishing Company. This book was released on 2020-05-29 with total page 1109 pages. Available in PDF, EPUB and Kindle. Book excerpt: This bible of family practice for primary care clinicians and students provides current national practice guidelines for professional standards of care across the life span. Concise and clearly organized, this resource features detailed, step-by-step instructions for physical examinations and diagnostic testing in the outpatient setting, information on health promotion, care guidelines, dietary information, information on culturally responsive care, patient resources, and abundant patient-education handouts. Now in color with abundant images and illustrations, this fifth edition features thoroughly updated guidelines and recommendations to reflect latest in practice, as well as many new guidelines. Each of the diagnoses includes definition, incidence, pathogenesis, predisposing factors, common complaints, signs/symptoms, subjective data, physical exam and diagnostic tests, differential diagnosis, and a care plan. Key Features: Presents information for disorders in consistent format for ease of use Highlights key considerations with Practice Pointers Provides individual care points for pediatric, pregnant, and geriatric patients Includes 138 printable Patient Teaching Guides Offers 18 procedure guidelines and routine health maintenance guidelines Features appendices that provide guidelines on normal lab values, special diets, Tanner’s Sexual Maturity Stages, and teeth

Download or read book Family Practice Guidelines Fourth Edition written by Jill C. Cash, MSN, APN, FNP-BC and published by Springer Publishing Company. This book was released on 2017-01-20 with total page 1017 pages. Available in PDF, EPUB and Kindle. Book excerpt: Print version of the book includes free access to the app (web, iOS, and Android), which offers interactive Q&A review plus the entire text of the print book! Please note the app is included with print purchase only. This bible of family practice for primary care students and clinicians provides current national practice guidelines for professional standards of care across the life span. Concise and clearly organized, the resource features detailed, step-by-step instructions for physical examinations and diagnostic testing in the outpatient setting, information on health promotion, care guidelines, dietary information, information on culturally responsive care, patient resources, and abundant patient education handouts. This fourth edition is updated to include new evidence-based guidelines for rheumatology, public health (featuring updated information on substance abuse, violence, obesity, homelessness, and lesbian health), the sports physical exam and interventions, endocrinology, the 2015 Beers Criteria, new Centers for Disease Control and Prevention (CDC) recommendations for health maintenance, posttraumatic stress disorder (PTSD) assessment and management, restless legs syndrome, sexual dysfunction treatment, and psychiatric disorders. Several new and updated Patient Teaching Guides—with printable education points—add to the book’s outstanding utility as a thorough and reliable clinical resource. Each of the 268 diagnoses includes definition, incidence, pathogenesis, predisposing factors, common complaints, signs/symptoms, subjective data, physical exam and diagnostic tests, differential diagnosis, and a care plan. New to the Fourth Edition: New and updated guidelines for: Rheumatology: polymyalgia rheumatica, Sjögren’s syndome, psoriatic arthropathy, pseudogout (calcium pyrophosphate dihydrate), ankylosing spondolitis, reactive arthritis, Raynaud’s syndrome Public Health: substance abuse, violence, obesity, homelessness, lesbian health Sports Exam: assessment and treatment 2015 Beers Criteria CDC recommendations: vaccine and cancer screening Endocrinology: diabetes management and new Food and Drug Administration–approved medications Updated to reflect the Whelton 2017 guidelines for hypertension Neurology: PTSD and restless legs syndrome management Sexual dysfunction Bipolar and other behavioral health disorders New and updated Patient Teaching Guides Key Features: Presents information for 268 disorders in consistent format for ease of use Highlights key considerations with Practice Pointers Provides individual care points for pediatric, pregnant, and geriatric patients Includes 138 printable Patient Teaching Guides Offers 18 procedure guidelines and routine health maintenance guidelines

Download or read book CDC Yellow Book 2018 Health Information for International Travel written by Centers for Disease Control and Prevention CDC and published by Oxford University Press. This book was released on 2017-04-17 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Download or read book Family Practice Guidelines written by Jill C. Cash and published by Springer Publishing Company. This book was released on 2010-11-18 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Print+CourseSmart

Download or read book Family Practice Guidelines Third Edition written by Jill C. Cash and published by Springer Publishing Company. This book was released on 2014-02-10 with total page 1032 pages. Available in PDF, EPUB and Kindle. Book excerpt: Print+CourseSmart

Download or read book Caring for People who Sniff Petrol Or Other Volatile Substances written by National Health and Medical Research Council (Australia) and published by . This book was released on 2011 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: These guidelines provide recommendations that outline the critical aspects of infection prevention and control. The recommendations were developed using the best available evidence and consensus methods by the Infection Control Steering Committee. They have been prioritised as key areas to prevent and control infection in a healthcare facility. It is recognised that the level of risk may differ according to the different types of facility and therefore some recommendations should be justified by risk assessment. When implementing these recommendations all healthcare facilities need to consider the risk of transmission of infection and implement according to their specific setting and circumstances.

Download or read book Family Practice Guidelines written by Jill C. Cash, MSN, APN, FNP-BC and published by Springer Publishing Company. This book was released on 2023-01-30 with total page 1009 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for earlier editions: "This is a wonderful book for both novice and experienced physician assistants and nurse practitioners. This latest edition will see frequent use in your daily practice.” "Score: 100, 5 stars--Doody's Medical Reviews "This textbook provides comprehensive coverage of primary care disorders in an easy-to-read format and contains invaluable step-by-step instructions for evaluating and managing primary care patients. . . [It] belongs in every NP and PA's reference library. I highly recommend this wonderful textbook." Maria T. Leik, MSN, FNP-BC, ANP-BC, GNP-BC President, National ARNP Services, Inc. This core nursing resource has long served as an essential text for thousands of NP students and as a valued clinical reference for family practice and primary care clinicians. The sixth edition continues to provide current practice guidelines and professional standards of care across the life span, with the addition of updated information in all chapters, updated patient teaching guides and charts, and new charts featuring enhanced readability. The book provides new content on COVID-19 treatment and vaccines, and new guidelines for dermatology (including photos), respiratory disease, cardiovascular disease, genitourinary considerations, neurologic conditions, and infectious diseases. Offering succinct and practical counsel, the book features detailed, step-by-step instructions for physical examinations and diagnostic testing, information on health promotion, guidelines of care, dietary information, common procedures, and patient resources. Chapters are organized by body system, with disorders alphabetized for ease of reference. Client Teaching Guides—available in print and digital format—perform double duty as both patient handouts and concise study tools. Consistent guidelines for more than 275 disorders facilitate ease of use and Clinical Pearls highlight key information. In addition, website links are incorporated throughout for easy access to additional information. New to the Sixth Edition: Updated information in all chapters including new clinical content for each body system New tables, charts, and algorithms Updated CDC guidelines on health maintenance and immunization schedules New dermatology guidelines including color photos of skin rashes/disorders Updated guidelines for heart failure and hypertension Focused guidelines for the management of asthma Updated management of urinary tract infections, erectile dysfunction, and premature ejaculation Key updates for stroke management Current CDC guidelines for management of COVID-19 Key Features: Presents consistent guidelines for over 275 disorders providing quick access to information Highlights key considerations for practice Addresses care points for pediatric, pregnant, and geriatric patients Includes Client Teaching Guides serving as both patient “take-home” teaching supplements and study guides for students

Download or read book Clinical practice guidelines for influenza written by World Health Organization and published by World Health Organization. This book was released on 2024-09-12 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of these updated clinical guidelines for influenza is to assist clinicians in the care of persons with suspected or confirmed influenza virus infection. Recommendations include the management of both severe and non-severe influenza and also the use of antiviral medications to prevent influenza virus infection in individuals exposed to the virus in the previous 48 hours. This update applies to patients with seasonal influenza viruses, pandemic influenza viruses and novel influenza A viruses known to cause severe illness in infected humans (zoonotic influenza), such as avian influenza A(H5N1), A(H5N6) and A(H7N9). This update also includes baseline risk estimates for hospitalization and death pooled from observational studies, and proposed definitions of patients at high or extremely high risk of developing severe influenza, so as to enable the recommendations to be targeted appropriately.

Download or read book Immunotherapy of Hepatocellular Carcinoma written by Tim F. Greten and published by Springer. This book was released on 2018-08-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.