Download or read book Power Analysis of Trials with Multilevel Data written by Mirjam Moerbeek and published by CRC Press. This book was released on 2015-07-01 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Power Analysis of Trials with Multilevel Data is a valuable reference for anyone who wants to perform power calculations on trials with hierarchical data. It provides a thorough overview of power analysis, familiarizing you with terminology and notation, outlining the key concepts of statistical power and power analysis, and covering all common hierarchical designs.

Download or read book Introduction to Power Analysis written by E. C. Hedberg and published by SAGE Publications. This book was released on 2017-12-05 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Power Analysis: Two-Group Studies provides readers with the background, examples, and explanation they need to read technical papers and materials that include complex power analyses. This clear and accessible guide explains the components of test statistics and their sampling distributions, and author Eric Hedberg walks the reader through the simple and complex considerations of this research question. Filled with graphics and examples, the reader is taken on a tour of power analyses from covariates to clusters, seeing how the complicated task of comparing two groups, and the power analysis, can be made easy.

Download or read book Doing Meta Analysis with R written by Mathias Harrer and published by CRC Press. This book was released on 2021-09-15 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Doing Meta-Analysis with R: A Hands-On Guide serves as an accessible introduction on how meta-analyses can be conducted in R. Essential steps for meta-analysis are covered, including calculation and pooling of outcome measures, forest plots, heterogeneity diagnostics, subgroup analyses, meta-regression, methods to control for publication bias, risk of bias assessments and plotting tools. Advanced but highly relevant topics such as network meta-analysis, multi-three-level meta-analyses, Bayesian meta-analysis approaches and SEM meta-analysis are also covered. A companion R package, dmetar, is introduced at the beginning of the guide. It contains data sets and several helper functions for the meta and metafor package used in the guide. The programming and statistical background covered in the book are kept at a non-expert level, making the book widely accessible. Features • Contains two introductory chapters on how to set up an R environment and do basic imports/manipulations of meta-analysis data, including exercises • Describes statistical concepts clearly and concisely before applying them in R • Includes step-by-step guidance through the coding required to perform meta-analyses, and a companion R package for the book

Download or read book Multilevel Modeling Methods with Introductory and Advanced Applications written by Ann A. O'Connell and published by IAP. This book was released on 2022-03-01 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multilevel Modeling Methods with Introductory and Advanced Applications provides a cogent and comprehensive introduction to the area of multilevel modeling for methodological and applied researchers as well as advanced graduate students. The book is designed to be able to serve as a textbook for a one or two semester course in multilevel modeling. The topics of the seventeen chapters range from basic to advanced, yet each chapter is designed to be able to stand alone as an instructional unit on its respective topic, with an emphasis on application and interpretation. In addition to covering foundational topics on the use of multilevel models for organizational and longitudinal research, the book includes chapters on more advanced extensions and applications, such as cross-classified random effects models, non-linear growth models, mixed effects location scale models, logistic, ordinal, and Poisson models, and multilevel mediation. In addition, the volume includes chapters addressing some of the most important design and analytic issues including missing data, power analyses, causal inference, model fit, and measurement issues. Finally, the volume includes chapters addressing special topics such as using large-scale complex sample datasets, and reporting the results of multilevel designs. Each chapter contains a section called Try This!, which poses a structured data problem for the reader. We have linked our book to a website (http://modeling.uconn.edu) containing data for the Try This! section, creating an opportunity for readers to learn by doing. The inclusion of the Try This! problems, data, and sample code eases the burden for instructors, who must continually search for class examples and homework problems. In addition, each chapter provides recommendations for additional methodological and applied readings.

Download or read book Multilevel Analysis written by Joop J. Hox and published by Routledge. This book was released on 2017-09-14 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applauded for its clarity, this accessible introduction helps readers apply multilevel techniques to their research. The book also includes advanced extensions, making it useful as both an introduction for students and as a reference for researchers. Basic models and examples are discussed in nontechnical terms with an emphasis on understanding the methodological and statistical issues involved in using these models. The estimation and interpretation of multilevel models is demonstrated using realistic examples from various disciplines including psychology, education, public health, and sociology. Readers are introduced to a general framework on multilevel modeling which covers both observed and latent variables in the same model, while most other books focus on observed variables. In addition, Bayesian estimation is introduced and applied using accessible software.

Download or read book Optimization of Behavioral Biobehavioral and Biomedical Interventions written by Linda M. Collins and published by Springer. This book was released on 2018-07-28 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Behavioral, biobehavioral, and biomedical interventions are programs with the objective of improving and maintaining human health and well-being, broadly defined, in individuals, families, schools, organizations, or communities. These interventions may be aimed at, for example, preventing or treating disease, promoting physical and mental health, preventing violence, or improving academic achievement. This book provides additional information on a principled empirical framework for developing interventions that are more effective, efficient, economical, and scalable. This framework is introduced in the monograph, "Optimization of Behavioral, Biobehavioral, and Biomedical Interventions: The Multiphase Optimization Strategy (MOST)" by Linda M. Collins (Springer, 2018). The present book is focused on advanced topics related to MOST. The chapters, all written by experts, are devoted to topics ranging from experimental design and data analysis to development of a conceptual model and implementation of a complex experiment in the field. Intervention scientists who are preparing to apply MOST will find this book an important reference and guide for their research. Fields to which this work pertains include public health (medicine, nursing, health economics, implementation sciences), behavioral sciences (psychology, criminal justice), statistics, and education.

Download or read book Practical Statistical Power Analysis written by Zhiyong Zhang and published by Isdsa Press. This book was released on 2018-05 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of conducting a statistical power analysis at the beginning of a study is universally accepted. Without careful planning, a study can easily fail to detect an existing effect by chance. This book teaches how to conduct power analysis for a range of models from correlation and t-test to structural equation models and multilevel models. Both a graphical Web software WebPower and an R package are introduced to practically conduct the analysis.

Download or read book Design and Analysis of Pragmatic Trials written by Song Zhang and published by CRC Press. This book was released on 2023-05-16 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book begins with an introduction of pragmatic cluster randomized trials (PCTs) and reviews various pragmatic issues that need to be addressed by statisticians at the design stage. It discusses the advantages and disadvantages of each type of PCT, and provides sample size formulas, sensitivity analyses, and examples for sample size calculation. The generalized estimating equation (GEE) method will be employed to derive sample size formulas for various types of outcomes from the exponential family, including continuous, binary, and count variables. Experimental designs that have been frequently employed in PCTs will be discussed, including cluster randomized designs, matched-pair cluster randomized design, stratified cluster randomized design, stepped-wedge cluster randomized design, longitudinal cluster randomized design, and crossover cluster randomized design. It demonstrates that the GEE approach is flexible to accommodate pragmatic issues such as hierarchical correlation structures, different missing data patterns, randomly varying cluster sizes, etc. It has been reported that the GEE approach leads to under-estimated variance with limited numbers of clusters. The remedy for this limitation is investigated for the design of PCTs. This book can assist practitioners in the design of PCTs by providing a description of the advantages and disadvantages of various PCTs and sample size formulas that address various pragmatic issues, facilitating the proper implementation of PCTs to improve health care. It can also serve as a textbook for biostatistics students at the graduate level to enhance their knowledge or skill in clinical trial design. Key Features: Discuss the advantages and disadvantages of each type of PCTs, and provide sample size formulas, sensitivity analyses, and examples. Address an unmet need for guidance books on sample size calculations for PCTs; A wide variety of experimental designs adopted by PCTs are covered; The sample size solutions can be readily implemented due to the accommodation of common pragmatic issues encountered in real-world practice; Useful to both academic and industrial biostatisticians involved in clinical trial design; Can be used as a textbook for graduate students majoring in statistics and biostatistics.

Download or read book Textbook of Clinical Trials in Oncology written by Susan Halabi and published by CRC Press. This book was released on 2019-04-24 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is an increasing need for educational resources for statisticians and investigators. Reflecting this, the goal of this book is to provide readers with a sound foundation in the statistical design, conduct, and analysis of clinical trials. Furthermore, it is intended as a guide for statisticians and investigators with minimal clinical trial experience who are interested in pursuing a career in this area. The advancement in genetic and molecular technologies have revolutionized drug development. In recent years, clinical trials have become increasingly sophisticated as they incorporate genomic studies, and efficient designs (such as basket and umbrella trials) have permeated the field. This book offers the requisite background and expert guidance for the innovative statistical design and analysis of clinical trials in oncology. Key Features: Cutting-edge topics with appropriate technical background Built around case studies which give the work a "hands-on" approach Real examples of flaws in previously reported clinical trials and how to avoid them Access to statistical code on the book’s website Chapters written by internationally recognized statisticians from academia and pharmaceutical companies Carefully edited to ensure consistency in style, level, and approach Topics covered include innovating phase I and II designs, trials in immune-oncology and rare diseases, among many others

Download or read book Multilevel Modelling for Public Health and Health Services Research written by Alastair H. Leyland and published by Springer Nature. This book was released on 2020-02-28 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book is a practical introduction to multilevel modelling or multilevel analysis (MLA) – a statistical technique being increasingly used in public health and health services research. The authors begin with a compelling argument for the importance of researchers in these fields having an understanding of MLA to be able to judge not only the growing body of research that uses it, but also to recognise the limitations of research that did not use it. The volume also guides the analysis of real-life data sets by introducing and discussing the use of the multilevel modelling software MLwiN, the statistical package that is used with the example data sets. Importantly, the book also makes the training material accessible for download – not only the datasets analysed within the book, but also a freeware version of MLwiN to allow readers to work with these datasets. The book’s practical review of MLA comprises: Theoretical, conceptual, and methodological background Statistical background The modelling process and presentation of research Tutorials with example datasets Multilevel Modelling for Public Health and Health Services Research: Health in Context is a practical and timely resource for public health and health services researchers, statisticians interested in the relationships between contexts and behaviour, graduate students across these disciplines, and anyone interested in utilising multilevel modelling or multilevel analysis. “Leyland and Groenewegen’s wealth of teaching experience makes this book and its accompanying tutorials especially useful for a practical introduction to multilevel analysis.” ̶ Juan Merlo, Professor of Social Epidemiology, Lund University “Comprehensive and insightful. A must for anyone interested in the applications of multilevel modelling to population health”. ̶ S. (Subu) V. Subramanian, Professor of Population Health and Geography, Harvard University

Download or read book Handbook of Regression Modeling in People Analytics written by Keith McNulty and published by CRC Press. This book was released on 2021-07-29 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the recent rapid growth in machine learning and predictive analytics, many of the statistical questions that are faced by researchers and practitioners still involve explaining why something is happening. Regression analysis is the best ‘swiss army knife’ we have for answering these kinds of questions. This book is a learning resource on inferential statistics and regression analysis. It teaches how to do a wide range of statistical analyses in both R and in Python, ranging from simple hypothesis testing to advanced multivariate modelling. Although it is primarily focused on examples related to the analysis of people and talent, the methods easily transfer to any discipline. The book hits a ‘sweet spot’ where there is just enough mathematical theory to support a strong understanding of the methods, but with a step-by-step guide and easily reproducible examples and code, so that the methods can be put into practice immediately. This makes the book accessible to a wide readership, from public and private sector analysts and practitioners to students and researchers. Key Features: • 16 accompanying datasets across a wide range of contexts (e.g. academic, corporate, sports, marketing) • Clear step-by-step instructions on executing the analyses. • Clear guidance on how to interpret results. • Primary instruction in R but added sections for Python coders. • Discussion exercises and data exercises for each of the main chapters. • Final chapter of practice material and datasets ideal for class homework or project work.

Download or read book Linear Mixed Models written by Brady T. West and published by CRC Press. This book was released on 2022-06-24 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly recommended by JASA, Technometrics, and other leading statistical journals, the first two editions of this bestseller showed how to easily perform complex linear mixed model (LMM) analyses via a variety of software programs. Linear Mixed Models: A Practical Guide Using Statistical Software, Third Edition continues to lead readers step-by-step through the process of fitting LMMs. The third edition provides a comprehensive update of the available tools for fitting linear mixed-effects models in the newest versions of SAS, SPSS, R, Stata, and HLM. All examples have been updated, with a focus on new tools for visualization of results and interpretation. New conceptual and theoretical developments in mixed-effects modeling have been included, and there is a new chapter on power analysis for mixed-effects models. Features: •Dedicates an entire chapter to the key theories underlying LMMs for clustered, longitudinal, and repeated measures data •Provides descriptions, explanations, and examples of software code necessary to fit LMMs in SAS, SPSS, R, Stata, and HLM •Contains detailed tables of estimates and results, allowing for easy comparisons across software procedures •Presents step-by-step analyses of real-world data sets that arise from a variety of research settings and study designs, including hypothesis testing, interpretation of results, and model diagnostics •Integrates software code in each chapter to compare the relative advantages and disadvantages of each package •Supplemented by a website with software code, datasets, additional documents, and updates Ideal for anyone who uses software for statistical modeling, this book eliminates the need to read multiple software-specific texts by covering the most popular software programs for fitting LMMs in one handy guide. The authors illustrate the models and methods through real-world examples that enable comparisons of model-fitting options and results across the software procedures.

Download or read book Statistical Methods in Psychiatry and Related Fields written by Ralitza Gueorguieva and published by CRC Press. This book was released on 2017-11-20 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data collected in psychiatry and related fields are complex because outcomes are rarely directly observed, there are multiple correlated repeated measures within individuals, there is natural heterogeneity in treatment responses and in other characteristics in the populations. Simple statistical methods do not work well with such data. More advanced statistical methods capture the data complexity better, but are difficult to apply appropriately and correctly by investigators who do not have advanced training in statistics. This book presents, at a non-technical level, several approaches for the analysis of correlated data: mixed models for continuous and categorical outcomes, nonparametric methods for repeated measures and growth mixture models for heterogeneous trajectories over time. Separate chapters are devoted to techniques for multiple comparison correction, analysis in the presence of missing data, adjustment for covariates, assessment of mediator and moderator effects, study design and sample size considerations. The focus is on the assumptions of each method, applicability and interpretation rather than on technical details. Features Provides an overview of intermediate to advanced statistical methods applied to psychiatry. Takes a non-technical approach with mathematical details kept to a minimum. Includes lots of detailed examples from published studies in psychiatry and related fields. Software programs, data sets and output are available on a supplementary website. The intended audience are applied researchers with minimal knowledge of statistics, although the book could also benefit collaborating statisticians. The book, together with the online materials, is a valuable resource aimed at promoting the use of appropriate statistical methods for the analysis of repeated measures data. Ralitza Gueorguieva is a Senior Research Scientist at the Department of Biostatistics, Yale School of Public Health. She has more than 20 years experience in statistical methodology development and collaborations with psychiatrists and other researchers, and is the author of over 130 peer-reviewed publications.

Download or read book Compositional Data Analysis in Practice written by Michael Greenacre and published by CRC Press. This book was released on 2018-07-17 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compositional Data Analysis in Practice is a user-oriented practical guide to the analysis of data with the property of a constant sum, for example percentages adding up to 100%. Compositional data can give misleading results if regular statistical methods are applied, and are best analysed by first transforming them to logarithms of ratios. This book explains how this transformation affects the analysis, results and interpretation of this very special type of data. All aspects of compositional data analysis are considered: visualization, modelling, dimension-reduction, clustering and variable selection, with many examples in the fields of food science, archaeology, sociology and biochemistry, and a final chapter containing a complete case study using fatty acid compositions in ecology. The applicability of these methods extends to other fields such as linguistics, geochemistry, marketing, economics and finance. R Software The following repository contains data files and R scripts from the book https://github.com/michaelgreenacre/CODAinPractice. The R package easyCODA, which accompanies this book, is available on CRAN -- note that you should have version 0.25 or higher. The latest version of the package will always be available on R-Forge and can be installed from R with this instruction: install.packages("easyCODA", repos="http://R-Forge.R-project.org").

Download or read book Bayesian Disease Mapping written by Andrew B. Lawson and published by CRC Press. This book was released on 2018-05-20 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the second edition, many new Bayesian tools and methods have been developed for space-time data analysis, the predictive modeling of health outcomes, and other spatial biostatistical areas. Exploring these new developments, Bayesian Disease Mapping: Hierarchical Modeling in Spatial Epidemiology, Third Edition provides an up-to-date, cohesive account of the full range of Bayesian disease mapping methods and applications. In addition to the new material, the book also covers more conventional areas such as relative risk estimation, clustering, spatial survival analysis, and longitudinal analysis. After an introduction to Bayesian inference, computation, and model assessment, the text focuses on important themes, including disease map reconstruction, cluster detection, regression and ecological analysis, putative hazard modeling, analysis of multiple scales and multiple diseases, spatial survival and longitudinal studies, spatiotemporal methods, and map surveillance. It shows how Bayesian disease mapping can yield significant insights into georeferenced health data. The target audience for this text is public health specialists, epidemiologists, and biostatisticians who need to work with geo-referenced health data.

Download or read book Modern Directional Statistics written by Christophe Ley and published by CRC Press. This book was released on 2017-08-03 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Directional Statistics collects important advances in methodology and theory for directional statistics over the last two decades. It provides a detailed overview and analysis of recent results that can help both researchers and practitioners. Knowledge of multivariate statistics eases the reading but is not mandatory. The field of directional statistics has received a lot of attention over the past two decades, due to new demands from domains such as life sciences or machine learning, to the availability of massive data sets requiring adapted statistical techniques, and to technological advances. This book covers important progresses in distribution theory,high-dimensional statistics, kernel density estimation, efficient inference on directional supports, and computational and graphical methods. Christophe Ley is professor of mathematical statistics at Ghent University. His research interests include semi-parametrically efficient inference, flexible modeling, directional statistics and the study of asymptotic approximations via Stein’s Method. His achievements include the Marie-Jeanne Laurent-Duhamel prize of the Société Française de Statistique and an elected membership at the International Statistical Institute. He is associate editor for the journals Computational Statistics & Data Analysis and Econometrics and Statistics. Thomas Verdebout is professor of mathematical statistics at Université libre de Bruxelles (ULB). His main research interests are semi-parametric statistics, high- dimensional statistics, directional statistics and rank-based procedures. He has won an annual prize of the Belgian Academy of Sciences and is an elected member of the International Statistical Institute. He is associate editor for the journals Statistics and Probability Letters and Journal of Multivariate Analysis.

Download or read book Introduction to Power Analysis written by E. C. Hedberg and published by SAGE Publications. This book was released on 2017-12-05 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Power Analysis: Two-Group Studies provides readers with the background, examples, and explanation they need to read technical papers and materials that include complex power analyses. This clear and accessible guide explains the components of test statistics and their sampling distributions, and author Eric Hedberg walks the reader through the simple and complex considerations of this research question. Filled with graphics and examples, the reader is taken on a tour of power analyses from covariates to clusters, seeing how the complicated task of comparing two groups, and the power analysis, can be made easy.