Download or read book Positron Emission Mammography Imaging written by and published by . This book was released on 2003 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt: This paper examines current trends in Positron Emission Mammography (PEM) instrumentation and the performance tradeoffs inherent in them. The most common geometry is a pair of parallel planes of detector modules. They subtend a larger solid angle around the breast than conventional PET cameras, and so have both higher efficiency and lower cost. Extensions to this geometry include encircling the breast, measuring the depth of interaction (DOI), and dual-modality imaging (PEM and x-ray mammography, as well as PEM and x-ray guided biopsy). The ultimate utility of PEM may not be decided by instrument performance, but by biological and medical factors, such as the patient to patient variation in radiotracer uptake or the as yet undetermined role of PEM in breast cancer diagnosis and treatment.

Download or read book The Evaluation of a Positron Emission Mammography PEM System Using Images Co registered with X ray Mammograms written by and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book PET CT in Breast Cancer written by Rakesh Kumar and published by Springer Nature. This book was released on 2023-07-26 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide crisp information related to pathology, management and radiological/molecular imaging in breast carcinoma, along with detailed information on FDG PET-CT in breast cancer, normal variants, artefacts, pitfalls with atlas illustrations. The book is unique in providing quick reference to practice of PET/CT in breast cancer. The initial few chapters are related to the pathology and management of breast carcinoma to help understand the pathophysiology of breast cancer before going to the imaging. The chapter on imaging in breast cancer highlights the role of different imaging modalities for different indications to the reader. The last four chapters describe in detail the role, normal variants, artefacts and pitfalls of FDG PET/CT along with recent molecular imaging advances in breast cancer. Written by Pathology, Oncology, Radiology and Nuclear Medicine experts from different countries with enormous experience in breast cancer practice, the book addresses nuclear medicine physicians and radiologists, but it may be of interest to a wider medical community, including oncologists and radiotherapists.

Download or read book Attenuation Correction with Region Growing Method Used in the Positron Emission Mammography Imaging System Supported by Knowledge Innovation Project of The Chinese Academy of Sciences KJCX2 EW N06 written by and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: The Positron Emission Mammography imaging system (PEMi) provides a novel nuclear diagnosis method dedicated for breast imaging. With a better resolution than whole body PET, PEMi can detect millimeter-sized breast tumors. To address the requirement of semi-quantitative analysis with a radiotracer concentration map of the breast, a new attenuation correction method based on a three-dimensional seeded region growing image segmentation (3DSRG-AC) method has been developed. The method gives a 3D connected region as the segmentation result instead of image slices. The continuity property of the segmentation result makes this new method free of activity variation of breast tissues. The threshold value chosen is the key process for the segmentation method. The first valley in the grey level histogram of the reconstruction image is set as the lower threshold, which works well in clinical application. Results show that attenuation correction for PEMi improves the image quality and the quantitative accuracy of radioactivity distribution determination. Attenuation correction also improves the probability of detecting small and early breast tumors.

Download or read book Analysis of Factors Affecting Positron Emission Mammography PEM Image Formation written by and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Image reconstruction for positron emission mammography (PEM) with the breast positioned between two parallel, planar detectors is usually performed by backprojection to image planes. Three important factors affecting PEM image reconstruction by backprojection are investigated: (1) image uniformity (flood) corrections, (2) image sampling (pixel size) and (3) count allocation methods. An analytic expression for uniformity correction is developed that incorporates factors for spatial-dependent detector sensitivity and geometric effects from acceptance angle limits on coincidence events. There is good agreement between experimental floods from a PEM system with a pixellated detector and numerical simulations. The analytic uniformity corrections are successfully applied to image reconstruction of compressed breast phantoms and reduce the necessity for flood scans at different image planes. Experimental and simulated compressed breast phantom studies show that lesion contrast is improved when the image pixel size is half of, rather than equal to, the detector pixel size, though this occurs at the expense of some additional image noise. In PEM reconstruction counts usually are allocated to the pixel in the image plane intersected by the line of response (LOR) between the centers of the detection pixels. An alternate count allocation method is investigated that distributes counts to image pixels in proportion to the area of the tube of response (TOR) connecting the detection pixels that they overlay in the image plane. This TOR method eliminates some image artifacts that occur with the LOR method and increases tumor signal-to-noise ratios at the expense of a slight decrease in tumor contrast. Analysis of image uniformity, image sampling and count allocation methods in PEM image reconstruction points to ways of improving image formation. Further work is required to optimize image reconstruction parameters for particular detection or quantitation tasks.

Download or read book Positron Emission Mammography with Multiple Angle Acquisition written by and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron emission mammography (PEM) of F-18 fluorodeoxyglucose (FbG) uptake in breast tumors with dedicated detectors typically has been accomplished with two planar detectors in a fixed position with the breast under compression. The potential use of PEM imaging at two detector positions to guide stereotactic breast biopsy has motivated us to use PEM coincidence data acquired at two or more detector positions together in a single image reconstruction. Multiple angle PEM acquisition and iterative image reconstruction were investigated using point source and compressed breast phantom acquisitions with 5, 9, 12 and 15 mm diameter spheres and a simulated tumor:background activity concentration ratio of 6:1. Image reconstruction was performed with an iterative MLEM algorithm that used coincidence events between any two detector pixels on opposed detector heads at each detector position. This present study compared two acquisition protocols: 2 angle acquisition with detector angular positions of -15 and +15 degrees and 11 angle acquisition with detector positions spaced at 3 degree increments over the range -15 to +15 degrees. Three-dimensional image resolution was assessed for the point source acquisitions, and contrast and signal-to-noise metrics were evaluated for the compressed breast phantom with different simulated tumor sizes. Radial and tangential resolutions were similar for the two protocols, while normal resolution was better for the 2 angle acquisition. Analysis is complicated by the asymmetric point spread functions. Signal- to-noise vs. contrast tradeoffs were better for 11 angle acquisition for the smallest visible 9 mm sphere, while tradeoff results were mixed for the larger and more easily visible 12 mm and 15 mm diameter spheres. Additional study is needed to better understand the performance of limited angle tomography for PEM. PEM tomography experiments with complete angular sampling are planned.

Download or read book Lesion Detection and Quantitation of Positron Emission Mammography written by and published by . This book was released on 2001 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Positron Emission Mammography (PEM) scanner dedicated to breast imaging is being developed at our laboratory. We have developed a list mode likelihood reconstruction algorithm for this scanner. Here we theoretically study the lesion detection and quantitation. The lesion detectability is studied theoretically using computer observers. We found that for the zero-order quadratic prior, the region of interest observer can achieve the performance of the prewhitening observer with a properly selected smoothing parameter. We also study the lesion quantitation using the test statistic of the region of interest observer. The theoretical expressions for the bias, variance, and ensemble mean squared error of the quantitation are derived. Computer simulations show that the theoretical predictions are in good agreement with the Monte Carlo results for both lesion detection and quantitation.

Download or read book Diseases of the Chest Breast Heart and Vessels 2019 2022 written by Juerg Hodler and published by Springer. This book was released on 2019-02-19 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology.

Download or read book Multimodality Breast Imaging written by Beverly Hashimoto and published by Thieme. This book was released on 2011-01-01 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the previous edition:Well organised and beautifully illustrated...A good book for trainee breast radiologists and radiographers...[and] an extremely useful reference textbook for more experienced practitioners.--RAD MagazineThe second edition of this generously illustrated case-based reference provides a systematic visual collection of pathologic entities and a detailed assessment of how to optimize sonographic technique as well as how to approach the integration of mammography, sonography, MRI and PET/CT in breast cancer diagnosis. The book begins with a focus on teaching practical methods to analyze and incorporate mammographic, sonographic, and magnetic resonance findings in the clinical setting. The closing chapters are devoted to illustrating the applications of PET as demonstrated by specific clinical cases.Features of the second edition: Emphasis on the importance of high-resolution sonography Three new chapters on the use of MRI and PET in breast imaging Numerous new case studies -- including helpful pearls and pitfalls -- that focus on common and uncommon examples of metastatic and non-metastatic disease Charts and outlines that provide rapid reference for the clinical workup of a lesion More than 800 images that help identify both mammographic and sonographic abnormalities This thorough reference is ideal for radiologists, mammographers, oncologists, gynecologists and all clinicians looking to broaden their visual sonographic experience. Its user-friendly format makes it a handy text for radiology residents in breast rotations.

Download or read book Breast Cancer Uses and Opportunities for Molecular Imaging An Issue of PET Clinics E Book written by Elizabeth McDonald and published by Elsevier Health Sciences. This book was released on 2018-07-13 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of PET Clinics focuses on Breast Cancer: Uses and Opportunities for Molecular Imaging, and is edited by Drs. Elizabeth McDonald and Gary A. Ulaner. Articles will include: Overview of Breast Cancer Screening and Diagnosis; Nuclear Imaging for Osseous Staging; Therapeutic Role of FDG in Breast Cancer: Treatment Response; Clinical Potential of HER2 Receptor Imaging; Novel Targets for Imaging Breast Cancer: Amino Acid Imaging with Fluciclovine; Overview of Breast Cancer Therapy; Molecular Classification of Breast Cancer; Clinical Potential of Estrogen and Progesterone Receptor Imaging; Diagnostic Role of FDG in Breast Cancer: Discovery to Current; Imaging Breast Cancer Proliferation; Dedicated Breast Gamma Camera Imaging and Breast Positron Emission Tomography: Current Status and Future Directions; and more!

Download or read book Mammography and Beyond written by National Research Council and published by National Academies Press. This book was released on 2001-07-23 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year more than 180,000 new cases of breast cancer are diagnosed in women in the U.S. If cancer is detected when small and local, treatment options are less dangerous, intrusive, and costly-and more likely to lead to a cure. Yet those simple facts belie the complexity of developing and disseminating acceptable techniques for breast cancer diagnosis. Even the most exciting new technologies remain clouded with uncertainty. Mammography and Beyond provides a comprehensive and up-to-date perspective on the state of breast cancer screening and diagnosis and recommends steps for developing the most reliable breast cancer detection methods possible. This book reviews the dramatic expansion of breast cancer awareness and screening, examining the capabilities and limitations of current and emerging technologies for breast cancer detection and their effectiveness at actually reducing deaths. The committee discusses issues including national policy toward breast cancer detection, roles of public and private agencies, problems in determining the success of a technique, availability of detection methods to specific populations of women, women's experience during the detection process, cost-benefit analyses, and more. Examining current practices and specifying research and other needs, Mammography and Beyond will be an indispensable resource to policy makers, public health officials, medical practitioners, researchers, women's health advocates, and concerned women and their families.

Download or read book Quantitative Analysis of Metabolic Breast Images from Positron Emission Mammography PEM written by Marianne Aznar and published by . This book was released on 1999 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: "X-ray mammography cannot always distinguish between benign and malignant breast lesions. This leads to unnecessary biopsies, costs, and stress for the patient. Positron Emission Mammography (PEM) provides images of increased glucose metabolism in malignant tumours compared with healthy tissue. After injection of a radioactively-labelled glucose analog, cancerous tumours appear as bright spots on the breast image." --

Download or read book Positron Emission Tomography written by Dale L. Bailey and published by Springer Science & Business Media. This book was released on 2006-07-06 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential for students, science and medical graduates who want to understand the basic science of Positron Emission Tomography (PET), this book describes the physics, chemistry, technology and overview of the clinical uses behind the science of PET and the imaging techniques it uses. In recent years, PET has moved from high-end research imaging tool used by the highly specialized to an essential component of clinical evaluation in the clinic, especially in cancer management. Previously being the realm of scientists, this book explains PET instrumentation, radiochemistry, PET data acquisition and image formation, integration of structural and functional images, radiation dosimetry and protection, and applications in dedicated areas such as drug development, oncology, and gene expression imaging. The technologist, the science, engineering or chemistry graduate seeking further detailed information about PET, or the medical advanced trainee wishing to gain insight into the basic science of PET will find this book invaluable. This book is primarily repackaged content from the Basic Science section of the 'big' Valk book on PET. It contains new, completely revised and unchanged chapters covering the "basic sciences" section of the main book - total 18 chapters: 2 new (chapters 1, 16) 8 completely revised (chapters 4, 5, 8, 13, 14, 15, 17, 18) 3 minor corrections (chapters 2, 6, 11) 5 unchanged (chapters 3, 7, 9, 10, 12)

Download or read book Breast Imaging An Issue of Radiologic Clinics of North America E Book written by Sarah M. Friedewald and published by Elsevier Health Sciences. This book was released on 2017-04-19 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Radiologic Clinics of North America focuses on Breast Imaging, and is edited by Dr. Sarah M. Friedewald. Articles will include: Evidence to Support Screening Women in Their 40s; Evidence to Support Screening Women Annually; High Risk Screening and Use of Risk Assessment Models; Breast Tomosynthesis: Clinical Evidence; Breast Tomosynthesis: Practical Considerations; Synthesized Digital Mammography Imaging; Breast Density Legislation and Clinical Evidence; Whole Breast Screening Ultrasound Implemenation; Breast MRI in the Newly Diagnosed Breast Cancer Patient; MRI: Future Imaging Techniques; Breast PET-MR; Update on Pre-Operative Needle Localization Techniques, and more!

Download or read book Methods for a Dedicated Breast Cancer Scanner Combining Positron Emission Tomography PET and Mammography Imaging written by Geng Zeng and published by . This book was released on 2018 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: The PET/X breast imaging system is designed to be a compact positron emission tomography (PET) scanner with a rectangular field of view (FOV) that can be mounted directly over the conventional mammography scanner. This thesis studies the prototyping of this dedicated breast cancer scanner that combines PET and mammography, using mostly computer modeling methods, while the hardware of data acquisition system is being concurrently developed. Apart from processing scripts and functions, two major simulation software packages are used: SimSET and CatSim. The former models PET emission process and the latter models mammography projection. This thesis delves into the details of using these packages and presents results of applying them to the PET/X system. By studying reconstructed images using simulated PET data, this thesis characterizes the proposed PET/X scanner and estimates its performance upper bound. Under several idealized detector conditions, the PET/X scanner exceeds the design goal of detecting a 20% change of radiotracer concentration with high sensitivity and specificity. This thesis also explores the use of X-ray (mammography) images for necessary attenuation correction of the PET data. Preliminary result shows that the X-ray-based attenuation correction (XAC) method has potential to be a surrogate for ground truth attenuation correction for the PET/X system.

Download or read book Breast Cancer Imaging written by Marie Tartar and published by Elsevier Health Sciences. This book was released on 2008-01-01 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through a case-based approach, this book illustrates the best practices for all facets of breast cancer imaging - from screening of asymptomatic patients to cancer staging, identifying metastases, and assessing efficacy of treatment - in a succinct, practical source. Contributing authors from a wide range of subspecialties provide well-rounded guidance to meet the needs of today's multidisciplinary work environment. Presents multidisciplinary discussions on the advantages and/or limitations of all available modalities. Includes advice from leading experts on cross-sectional imaging, breast imaging, and PET/CT, with input from radiation oncology, medical oncology, and breast surgery, to span the complete spectrum of care from screening to diagnosis to treatment, reflecting today's team approach to patient care. Covers all imaging modalities to help you correlate disease presentations on mammography, CT, MR, US, and PET images. Offers a very practical, clinical, concise approach to the subject in a case-based format. Provides over 1,000 high-resolution images of disease appearance for comparison with the findings you encounter in your practice.

Download or read book The Evaluation of a Positron Emission Mammography PEM System Using Images Co registered with X ray Mammograms written by Alanah M. Bergman and published by . This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: