Download or read book Polymeric microarchitectures for tissue regeneration and drug screening written by Ranjith Kumar Kankala and published by Frontiers Media SA. This book was released on 2023-03-07 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biopolymeric Materials for Tissue Regeneration Cell Manufacturing and Drug Delivery written by David Alfonso Castilla-Casadiego and published by . This book was released on 2021 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of materials for tissue regeneration, cell manufacturing, and drug delivery is possible by the manipulation of polymer properties and the use of three different techniques including layer-by-layer, electrospinning, and molding technique. By applying the layer-by-layer technique over biomaterials, it is possible to develop polymeric multilayers that promote a more favorable environment for cellular functionality, increasing the possibility of improving their acceptance in the area of implantation. IRVASE demonstrated being a powerful technique that allows for a reliable characterization of the physical-chemical and thermal properties of the fabricated surfaces. This opens the possibility to monitor the design of surfaces with specific characteristics, with the use of different polymeric combinations or the number of formed multilayers over the surface. In addition, other results presented here have demonstrated that the multilayers could be a platform to induce signals to cells and improve their cellular activities, promoting the manufacturing of cells of high quality. On the other hand, this dissertation has demonstrated that nanofibrous materials that mimic the physical or morphological characteristics and a large percentage of the chemical composition of the extracellular matrix of tissue in the human body could also be designed by applying the electrospinning technique. It was possible to develop collagen and collagen/hydroxyapatite nanofibrous membranes for soft and bone tissue regeneration, preserving the chemical structure and biological function. Through the manipulation of the electrospinning equipment, voltage, and injection flow, it is possible to obtain control over the diameter, morphology, and orientation of the nanofibers. Finally, polymers can also be used to design a microneedle patch useful for drug delivery by applying the molding technique. This work demonstrated that a microneedle patch of chitosan was successfully created for the delivery of meloxicam. Chitosan/meloxicam patches presented an organized distribution and homogeneous dimension of microneedles. Results revealed that the chemical composition of chitosan and meloxicam were successfully preserved, and a penetration study showed a sustained insertion of microneedles in cadaver skin of a cow's ear. This dissertation demonstrated that polymers have the capacity to be used to fabricate materials for tissue regeneration, cell manufacturing, and drug delivery application.
Download or read book Bionanocomposites in Tissue Engineering and Regenerative Medicine written by Shakeel Ahmed and published by Woodhead Publishing. This book was released on 2021-06-03 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bionanocomposites in Tissue Engineering and Regenerative Medicine explores novel uses of these in tissue engineering and regenerative medicine. This book offers an interdisplinary approach, combining chemical, biomedical engineering, materials science and pharmacological aspects of the characterization, synthesis and application of bionanocomposites. Chapters cover a broad selection of bionanocomposites including chitosan, alginate and more, which are utilized in tissue engineering, wound healing, bone repair, drug formulation, cancer therapy, drug delivery, cartilage regeneration and dental implants. Additional sections of Bionanocomposites in Tissue Engineering and Regenerative Medicine discuss, in detail, the safety aspects and circular economy of bionanocomposites – offering an insight into the commercial and industrial aspects of these important materials. Bionanocomposites in Tissue Engineering and Regenerative Medicine will prove a highly useful text for for those in the fields of biomedical engineering, chemistry, pharmaceutics and materials science, both in academia and industrial R&D groups. Each bionanocomposite type is covered individually, providing specific and detailed information for each material Covers a range of tissue engineering and regenerative medicine applications, from dental and bone engineering to cancer therapy Offers an integrated approach, with contributions from authors across a variety of related disciplines, including biomedical engineering, chemistry and materials science
Download or read book Multiscale Cell Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine written by J. Miguel Oliveira and published by Elsevier. This book was released on 2023-11-28 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine addresses the key concepts involved in the interactions between cells and biomaterials in the musculoskeletal tissue engineering and regenerative medicine field. The updated developments and challenges of the mechanisms/mechanobiology and structure-function properties of those interactions, as well as emerging technologies underlying tissue-engineered scaffolding, are carefully discussed. Lastly, cell engineering and cell-based therapies, growth factors/drugs properties, vascularization, immunomodulation are also outlined. Given the large number of musculoskeletal disorders and related injuries that can affect muscles, bones and joints and lead to severe complications of the neuromuscular system, it is imperative to develop new treatment strategies to delay or repair associated diseases and to promote optimal long-term health. Presents the fundamentals of the complex interplay of cells with biomaterials in musculoskeletal tissue engineering Includes coverage of stem cells and cell-based therapies, in vitro and in vivo models, nanotechnology, bioprinting, computational modeling, regulatory and clinical translation, and much more Written by global leaders in the field
Download or read book Silk Based Biomaterials for Tissue Engineering Regenerative and Precision Medicine written by Subhas C. Kundu and published by Elsevier. This book was released on 2023-12-15 with total page 908 pages. Available in PDF, EPUB and Kindle. Book excerpt: Silk-based Biomaterials for Tissue Engineering, Regenerative and Precision Medicine, Second Edition is a must-have reference, providing comprehensive coverage of silk-based biomaterials and their importance in translational uses and biomedicine. This new edition considers the progress made in the past eight years, featuring many new chapters, including a discussion of cutting-edge fabrication methods and techniques, new and improved blends/composites, and an expanded range of applications in tissue engineering, regenerative and precision medicine. The book holistically reviews the types, structure and properties, processing methods, and specific biomedical applications for silk-based biomaterials. This will be a vital resource for materials and tissue engineering scientists, R&D departments in industry and academia, and academics interested in biomaterials, regenerative, and precision medicine. Covers all key silk biomaterial types, including mulberry, Bombyx mori and nonmulberry/wild silk protein fibroins, sericins and spider silk, as well as their composite blends and various structures and scaffold platforms Describes the cutting-edge processing techniques for each silk type, from traditional to nonconventional methods, such as using ionic liquids and engineering nanofibers and other biomedical matrices Explores a range of applications in tissue engineering and regenerative and precision medicine, including bioprinting, bioelectronics and medical devices
Download or read book The use of Biomaterials with Stem and Precursor Cells in Diseases of the Central Nervous System A Step to Clinical Trials written by Ulises Gomez-Pinedo and published by Frontiers Media SA. This book was released on 2021-05-31 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Polymer Based Additive Manufacturing written by Declan M. Devine and published by Springer Nature. This book was released on 2019-09-16 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to give readers a basic understanding of commonly used additive manufacturing techniques as well as the tools to fully utilise the strengths of additive manufacturing through the modelling and design phase all the way through to post processing. Guidelines for 3D-printed biomedical implants are also provided. Current biomedical applications of 3D printing are discussed, including indirect applications in the rapid manufacture of prototype tooling and direct applications in the orthopaedics, cardiovascular, drug delivery, ear-nose-throat, and tissue engineering fields. Polymer-Based Additive Manufacturing: Biomedical Applications is an ideal resource for students, researchers, and those working in industry seeking to better understand the medical applications of additive manufacturing.
Download or read book Nanotechnology and Tissue Engineering written by Cato T. Laurencin and published by CRC Press. This book was released on 2008-06-16 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanofabrication gives us the ability to mimic biological structures with molecular level precision. Offering a natural progression of topics, Nanotechnology and Tissue Engineering: The Scaffold provides a state-of-the-art account of groundbreaking research in this rapidly emerging area of biomedical engineering. Emphasizing the importance of scaffo
Download or read book Electrospun Polymeric Nanofibers written by R. Jayakumar and published by Springer Nature. This book was released on 2023-04-27 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume deals with the various fabrication techniques, surface functionalization and biomedical applications of polymeric fibers possessing different scale and structure. It provides an overview of fabrication techniques such as Co-axial, Centrifugal, Melt and Yarning to procure multiscale, tubular and layered fibrous scaffold employed for biomedical applications. The chapters in this volume discusse the surface/chemical functionalization of fibers which enhance the biological properties of the fibrous scaffolds as well as the development of hybrid, layered and external stimuli-responsive fibrous scaffolds that hold potential application in biosensor and other biomedical fields. In addition, recent advances and applications of polymeric multiscale fibers in tissue engineering, regenerative medicine and drug delivery are presented. The potential use of fibrous scaffolds in bone, neural, tendon/ligament and cardiac tissue engineering, nanofibers as an antimicrobial wound dressing, employed in cancer theragnostics and in the treatment of skin/periodontal infections are discussed. The volume provides expert knowledge on the fabrication techniques, development of different scale and hybrid structure fibers, surface functionalization, layered and external stimuli responsive fibrous scaffolds. It will be beneficial to material/biomaterials scientists, bioengineering and biotechnologists by providing a better understanding on the subject of the innovative applications of fibrous scaffolds in drug delivery, tissue engineering, wound dressings and regenerative medicine.
Download or read book Biofabrication and Biopolymeric Materials Innovation for Musculoskeletal Tissue Regeneration written by Farnaz Ghorbani and published by Frontiers Media SA. This book was released on 2022-04-25 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Polyester Drug Delivery Systems written by M. N. V. Ravi Kumar and published by CRC Press. This book was released on 2017-03-27 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the quest for innovative drug delivery systems attempting to meet the unmet needs in pharmaceutical space, research has taken a much more complicated path that poses a significant challenge for translation. Despite the progress made with novel materials, polyesters still remain at the helm of drug delivery technologies. This book provides a single source of reference of polyester drug delivery systems that covers a broad spectrum of materials design, manufacturing techniques, and applications.
Download or read book Marine Derived Biomaterials for Tissue Engineering Applications written by Andy H. Choi and published by Springer. This book was released on 2019-07-08 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest advances in marine structures and related biomaterials for applications in both soft- and hard-tissue engineering, as well as controlled drug delivery. It explores marine structures consisting of materials with a wide variety of characteristics that warrant their use as biomaterials. It also underlines the importance of exploiting natural marine resources for the sustainable development of novel biomaterials and discusses the resulting environmental and economic benefits. The book is divided into three major sections: the first covers the clinical application of marine biomaterials for drug delivery in tissue engineering, while the other two examine the clinical significance of marine structures in soft- and hard-tissue engineering, respectively. Focusing on clinically oriented applications, it is a valuable resource for dentists, oral and maxillofacial surgeons, orthopedic surgeons, and students and researchers in the field of tissue engineering.
Download or read book Bionanotechnology Emerging Applications of Bionanomaterials written by Ahmed Barhoum and published by Elsevier. This book was released on 2022-05-29 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bionanotechnology: Emerging Applications of Bionanomaterials highlights a wide range of industrial applications using bionanotechnologies, with biomedical applications prominent amongst these, including drug delivery, tissue engineering, wound healing, medical implants, medical diagnostics and therapy. Other key areas include energy harvesting and storage, water/waste treatment, papermaking, textiles, construction industry, automotive, aerospace. This book is a valuable resource for all those seeking to gain a fundamental understanding of how bionanomaterials are used in a variety of industry sectors. Bionanomaterials are molecular materials composed partially or completely of biological molecules - such as proteins, enzymes, viruses, DNA and biopolymers - as well as metal, metal oxides, and carbon nanomaterials. Bionanomaterials have drawn much attention for their use in a wide range of industrial applications, including scaffolds, dental implants, drug delivery, dialysis, biobatteries, biofuel cells, air purification, and water treatment. Assesses which bionanomaterial types are particularly suited to particular application areas Shows how bionanomaterials are being used for biotechnology, biomedicine, energy production, energy storage, and environmental remediation applications Highlights the challenges and interdisciplinary perspectives of bionanomaterials in science, biology, engineering, medicine, and technology, incorporating both fundamentals and applications
Download or read book Integrated Biomaterials for Biomedical Technology written by Murugan Ramalingam and published by John Wiley & Sons. This book was released on 2012-08-07 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cutting edge book provides all the important aspects dealing with the basic science involved in materials in biomedical technology, especially structure and properties, techniques and technological innovations in material processing and characterizations, as well as the applications. The volume consists of 12 chapters written by acknowledged experts of the biomaterials field and covers a wide range of topics and applications including: The different types of nanobiomaterials How to generate porous biomaterials for tissue engineering Calcium phosphate-based biomaterials intended for mineralized tissue regenerative applications Nanocrystalline form of calcium phosphates Design and fabrication of SiO2 nanoparticles New kinds of titanium alloy implants Injectable growth factor system based on bone morphogenetic proteins Impedance sensing of biological processes in mammalian cells Hydrogels-based implantable glucose sensors Molecular design of multifunctional polymers for gene transfection Hydrogels and their potential biomedical applications Hybrid biomaterials with high mechanical and biological properties
Download or read book Hydrogels written by Thakur Raghu Raj Singh and published by CRC Press. This book was released on 2018-02-28 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hydrogels are crosslinked, macromolecular polymeric materials arranged in a three-dimensional network, which can absorb and retain large amounts of water. Hydrogels are commonly used in clinical practice and experimental medicine for a wide range of applications, including drug delivery, tissue engineering and regenerative medicine, diagnostics, cellular immobilization, separation of biomolecules or cells, and barrier materials to regulate biological adhesions. This book elucidates the underlying concepts and emerging applications of hydrogels and will provide key case studies and critical analysis of the existing research.
Download or read book Principles of Tissue Engineering written by Robert Lanza and published by Academic Press. This book was released on 2020-03-26 with total page 1679 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fifth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and the application of tissue-engineering techniques for food production – is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the emerging technologies in the field. Organized into twenty-three parts, covering the basics of tissue growth and development, approaches to tissue and organ design, and a summary of current knowledge by organ system Introduces a new section and chapters on emerging technologies in the field Full-color presentation throughout
Download or read book Biologically Responsive Biomaterials for Tissue Engineering written by Iulian Antoniac and published by Springer Science & Business Media. This book was released on 2012-10-02 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developments in the area of biomaterials, bionanotechnology, tissue engineering, and medical devices are becoming the core of health care. Almost all medical specialties involve the use of biomaterials, and research plays a key role in the development of new and improved treatment modalities. This volume focuses on several current trends in tissue engineering, remodelling and regeneration. Leading researchers describe the use of nanomaterials to create new functionalities when interfaced with biological molecules or structures. In addition to coverage of basic science and engineering aspects, a range of applications in bionanotechnology are presented, including diagnostic devices, contrast agents, analytical tools, physical therapy applications, and vehicles for targeted drug delivery. The use of polymers, alloys, and composites, or a combination of these, for biomaterials applications in orthopaedics is also explored. These contributions represent essential reading for the biomaterials and biomedical engineering communities, and can serve as instructional course lectures targeted at graduate and post-graduate students.
