Download or read book Polyelectrolyte Complexes in the Dispersed and Solid State II written by Martin Müller and published by Springer. This book was released on 2013-08-23 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyelectrolyte Complexes for Tailoring of Wood Fibre Surfaces. Polyelectrolyte Complexes in Flocculation Applications. Spontaneous Assembly and Induced Aggregation of Food Proteins. Polyelectrolyte Complexes of DNA and Polycations as Gene Delivery Vectors. Sizing, Shaping and Pharmaceutical Applications of Polyelectrolyte Complex Nanoparticles.
Download or read book Polyelectrolyte Complexes in the Dispersed and Solid State I written by Martin Müller and published by Springer. This book was released on 2014-07-08 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Polymer Science enjoys a longstanding tradition and good reputation in its community. Each volume is dedicated to a current topic, and each review critically surveys one aspect of that topic, to place it within the context of the volume. The volumes typically summarize the significant developments of the last 5 to 10 years and discuss them critically, presenting selected examples, explaining and illustrating the important principles, and bringing together many important references of primary literature. On that basis, future research directions in the area can be discussed. Advances in Polymer Science volumes thus are important references for every polymer scientist, as well as for other scientists interested in polymer science - as an introduction to a neighboring field, or as a compilation of detailed information for the specialist.
Download or read book Polyelectrolyte Complexes in the Dispersed and Solid State written by Martin Müller and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Macromolecular Self Assembly written by Laurent Billon and published by John Wiley & Sons. This book was released on 2016-09-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes techniques of synthesis and self-assembly of macromolecules for developing new materials and improving functionality of existing ones. Because self-assembly emulates how nature creates complex systems, they likely have the best chance at succeeding in real-world biomedical applications. • Employs synthetic chemistry, physical chemistry, and materials science principles and techniques • Emphasizes self-assembly in solutions (particularly, aqueous solutions) and at solid-liquid interfaces • Describes polymer assembly driven by multitude interactions, including solvophobic, electrostatic, and obligatory co-assembly • Illustrates assembly of bio-hybrid macromolecules and applications in biomedical engineering
Download or read book Advanced Pharmacy written by Martin Masuelli and published by Bentham Science Publishers. This book was released on 2023-09-26 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Pharmacy is a textbook dedicated to advanced applications in pharmacy. The book balances information by including chapters that give basic knowledge and inform readers on the latest insights in pharmaceutical science. Authored by pharmacology experts and academics, each chapter highlights current knowledge in the field, presenting research in a didactic and educational manner for academics, researchers, and students who need to understand pharmacy. Additional features of the book include chapter summaries and references for advanced readers. Topics: Physical Pharmacy: Covers foundations of physical pharmacy, providing a solid understanding of the subject. Preformulation Studies: examines active pharmaceutical ingredient-excipent compatibility studies, a crucial aspect of drug formulation. Medicinal Chemistry Applications: explores medicinal chemistry applications using QSAR/QSPR theory. Computer-assisted Study: explains computer-assisted studies with the example of garlic organosulfur as an antioxidant agent. Enzymes in Biocatalysis: sheds light on enzyme characteristics, kinetics, production, and applications in biocatalysis. Antifungal Agents: provides insights into antifungal agents and their significance. Polysaccharides in Drug Delivery: explores the use of naturally and chemically sulfated polysaccharides in drug delivery systems. Immunomodulatory Plant Extracts: covers the evaluation of safety and benefits of immunomodulatory plant extracts. Biofilms and Persistent Cells: examines the development, causes, and consequences of biofilms and persistent cells. Analytical Methods for Drug Analysis: focuses on the development of analytical methods for analyzing drugs of abuse using experimental design. Steric Exclusion Chromatography: discusses steric exclusion chromatography, including chromatography of polymers in aqueous solutions. Intrinsic Viscosity Methods: explores intrinsic viscosity methods in natural polymer pharmaceutical excipients. Extraction Techniques in Green Analytical Chemistry: highlight environment-firendly techniques in analytical chemistry. Advanced Pharmacy is a comprehensive resource that bridges the gap between pharmaceutical research and practice, offering invaluable insights into the latest developments in the field. This textbook serves as an essential reference for both learners and scholars in basic and advanced courses in pharmacy and pharmaceutical science.
Download or read book Ionotropic Cross Linking of Biopolymers written by Amit Kumar Nayak and published by Elsevier. This book was released on 2024-04-15 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ionotropic Cross-Linking of Biopolymers: Applications in Drug Delivery provides in-depth insights and presents the latest advances in ionotropic cross-linked biopolymeric systems for drug delivery and related applications. Sections introduce the fundamentals of ionotropic cross-linking of biopolymers, including mechanisms, chemistry, cross-linking methods and gelation. Additional content delves into ionotropically cross-linked biopolymers based on a range of sources, including alginate, pectinate, carboxymethyl cellulose, gellan gum, chitosan, carboxymethylated gums, plant polysaccharide blends, and synthetic polymer blends. This is followed by a section focusing on ionotropically cross-linked biopolymeric systems, such as polymeric nanoparticles, microparticles, beads, and reinforced matrices. The last part of the book explores specific advanced drug delivery applications, before considering future opportunities and challenges in the field. This is a valuable resource for researchers and advanced students across polymer science, biomaterials, biomedicine, pharmaceutics, biotechnology, and chemistry, as well as scientists and R&D personnel working in pharmacy, drug delivery, and materials for biomedicine. Explains chemistry, mechanisms, preparation methods and applications of biopolymeric systems Covers a range of biopolymer sources, including alginate, pectinate, gellan gum, chitosan, and others Guides the reader to cutting-edge applications in drug delivery, drug release, cell delivery and tissue engineering
Download or read book Optimization of Micro Processes in Fine Particle Agglomeration by Pelleting Flocculation written by Benjamin Oyegbile and published by CRC Press. This book was released on 2016-06-22 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Efficient particle separation in order to meet stringent regulatory standards represent one of the biggest challenges facing the process industry operators today. Emerging environmental problems such as climate change, population growth and natural resource depletion make it more compelling to undertake research into alternative phase separation techniques and optimization of existing ones. Meeting this challenge requires innovative, revolutionary and integrated approach in the design and optimization of various unit processes in fine particle separation. Flocculation is widely used as an effective phase separation technique across many process industries such as water and wastewater treatment and in minerals processing. In this work, a new pre-treatment technique was developed using a patented bench scale reactor unit as a technical proof of concept. Furthermore, the book provides a valuable insight into the hydrodynamics and fluid-particle interactions within the agglomeration units. The relatively high solids content of the stable pellets (approximately 30 %) and very low residual turbidity of the post-sedimentation supernatant (7 NTU) clearly demonstrate the potential of this technique. In addition to significantly improving the subsequent solid-liquid separation efficiency, this study also showed that the effluent can be recycled back into the sewer network or utilized for non-portable reuse. The findings obtained from this research will be extremely useful in the scaling up and optimization of the reactor system.
Download or read book Integration of Biomaterials for Gene Therapy written by Rishabha Malviya and published by John Wiley & Sons. This book was released on 2023-10-10 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: INTEGRATION OF BIOMATERIALS FOR GENE THERAPY Brings industrial practitioners and researchers together to discuss how the deeper integration of biomaterial platforms could play a significant role in enabling breakthroughs in the application of gene editing for the treatment of human disease. This book comprises research and review articles from leading researchers with multidisciplinary experience. It discusses many broad topics, including nanoparticle-enabled gene therapy, inorganic nanocarrier-based gene delivery, non-viral delivery of nucleic acid, biocompatible hydrogels, silk, and polysaccharides-based gene delivery. Other gene delivery topics discussed include the use of smart and engineered biomaterials, combined therapy with growth factors and cell transportation, and the prospects and challenges in the treatment of different diseases, including cancer. This book bridges the knowledge of pharmaceutics, engineering, basic science, and clinical research fields in a way that will help the research community expedite the clinical application of these therapies for various diseases and conditions. Audience A broad range of researchers, scientists, and engineers in diverse fields such as materials science, biomedicine, biomedical engineering, biology, chemistry, physics, biotechnology, pharmacology, toxicology, and formulation scientists.
Download or read book Advanced Theranostic Materials written by Ashutosh Tiwari and published by John Wiley & Sons. This book was released on 2015-07-10 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book is covers the recent advances in the development on the regulation of such theragnosis system and their biomedical perspectives to act as a future nanomedicine. Advanced Theranostics Materialsis written by a distinguished group of contributors and provides comprehensive coverage of the current literature, up-to-date overview of all aspects of advanced theranostics materials ranging from system biology, diagnostics, imaging, image-guided therapy, therapeutics, biosensors, and translational medicine and personalized medicine, as well as the much broader task of covering most topics of biomedical research. The books focusses on the following topics: Part 1: System biology and translational medicine Aberrant Signaling Pathways: Hallmark of Cancer Cells and Target for Nanotherapeutics Application of Nanoparticles in Cancer Treatment Biomacromolecule-Gated Mesoporous Silica Drug Delivery Systems Construction of Functional DNA Nanostructures for Theranostic Applications Smart Polypeptide Nanocarriers for Malignancy Therapeutics Part 2: Imaging and therapeutics Dimercaptosuccinic acid-coated magnetic nanoparticles as a localized delivery system in cancer immunotherapy Cardiovascular nanomedicine Chitosan-based systems for sustained drug release Nanocapsules in biomedicine: promises and challenges Chitosan-based polyelectrolyte complexes: characteristics and application in formulation of particulate drug carriers Part 3: Diagnostics and featured prognostics Non-invasive Glucose Biosensors based on Nanomaterials Self/directed Assembly of Nanoparticles: A review on various approaches Ion exchangers – an open window for the development of advanced materials with pharmaceutical and medical applications New Titanium Alloys for Biomedical Applications
Download or read book Polyelectrolytes with Defined Molecular Architecture II written by Manfred Schmidt and published by Springer Science & Business Media. This book was released on 2004-02-20 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two volumes 165 and 166 Polyelectrolytes with Defined Molecular Architecture summarize recent progress in the field. The subjects comprise novel polyelectrolyte architectures including planar, cylindrical and spherical polyelectrolyte brushes as well as micelle, complex and membrane formation. Some solution properties such as conformation of flexible polyions, osmotic coefficients and electrophoretic properties are addressed along with recent progress in analytical theory and simulation.
Download or read book Advances in Physicochemical Properties of Biopolymers Part 1 written by Martin Masuelli and published by Bentham Science Publishers. This book was released on 2017-07-05 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last two decades have seen a number of significant advances in the methodology for evaluating the molecular weight distributions of polydispersed macromolecular systems in solution at the molecular level. This reference presents reviews on the progress in different analytical and characterization methods of biopolymers. Readers will find useful information about combinations of complex biopolymer analysis such as chromatographic or membrane based fractionation procedures combined with multiple detectors on line (multi-angle laser light scattering or MALLS). Key topics include: • refractive index, UV-Vis absorbance and intrinsic viscosity detection systems, • advances in SEC-MALLS (size exclusion chromatography coupled to multi-angle laser light scattering) and FFF-MALLS (field flow fractionation coupled on line to MALLS), • HPSEC-A4F-MALLS, matrix-assisted laser-desorption ionization (MALDI) • electrospray ionization (ESI) mass spectrometry • nuclear magnetic resonance (NMR) spectroscopy This reference is intended for students of applied chemistry and biochemistry who require information about biopolymer analysis and characterization.
Download or read book Whey Proteins written by Hilton C Deeth and published by Academic Press. This book was released on 2018-09-12 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whey Proteins: From Milk to Medicine addresses the basic properties of whey proteins including chemistry, analysis, heat sensitivity, interactions with other proteins and carbohydrates, modifications (hydrolysis, aggregation, conjugation), their industrial preparation, processing and applications, quality aspects including flavour and effects of storage, as well as their role in nutrition, sports and exercise, and health and wellness. Readers of Whey Proteins will gain a better understanding of the chemical nature of the various whey proteins in cow’s milk and the milk of other species. This includes their unique physical and functional properties; the industrial processes used to extract them from milk, to process them into various forms, and to modify them to enhance their functionality; and their nutritive value and application in the fields of sports and exercise science, infant nutrition and medicine. This book is an essential resource for food and nutrition researchers, dairy and food companies, pharmaceutical organizations, and graduate students. Presents up-to-date coverage of whey proteins from milk to medicine Contains a description of the production and properties of whey protein products Offers an overview of the effects of thermal and non-thermal processes on whey protein characteristics Describes the rationale for, and benefits of, using whey proteins in health and wellness preparations
Download or read book Rheology of Biological Soft Matter written by Isamu Kaneda and published by Springer. This book was released on 2016-11-16 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, a wide range subjects in biorheology are dealt with, from fundamentals to applications. The inclusion of quite substantial chapters concerned with application aspects such as the latest studies on foods, cosmetics, personal care products, and biological tissues, related regenerative medicine, is one of the features of the book. For the fundamental aspects, studies on the physicochemical characteristics of biopolymer, the key substance of soft matter, are listed. By contrast, in the application aspect, although the main topic is the rheology of foods, focusing on the "texture" of mastication or swallowing, novel studies on cosmetics and personal care products concerning feeling during the lubrication by those products are also considered. This book will engage both a professional and an academic audience interested in soft matter, especially as related to food, cosmetics, and personal care products. In particular, this work will have a special appeal to scientists and engineers in the food and cosmetics industries and to graduate students preparing for those fields.
Download or read book Dispersed and Deposited Polyelectrolyte Complexes and Their Interactions to Chiral Compounds and Proteins written by and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyelectrolyte complexation is a rapidly growing field with applications in functional multilayer (PEM) and nanoparticle (PEC) generation, where PEM films are deposited using Layer-by-Layer technique initiated by Decher and PECs are prepared using mixing-centrifugation technique initiated by our group. Its advantages (e.g. easy preparation) result in various applications in aqueous solution, especially in pharmaceutical and biomedical fields. Therefore, the objectives in this study are to explore interesting applications of polyelectrolyte complexation in the field of low molecular chiral compound and high molecular protein binding. Due to the rapidly growing demands for preparing optically pure compounds in the pharmaceutical field, herein, enantiospecific PEM and PEC were prepared using chiral polyelectrolytes (e.g. homo-polypeptide) and their ability of chiral recognition was investigated by ATR-FTIR, UV/Vis etc. Chiral PEM and PEC showed pronounced enantiospecificity for both small (amino acids, vitamin) and large (protein) chiral compounds. This chiral recognition is performed by a diffusion process of chiral compounds into PEM based on the structures of chiral selector (PEM, PEC) and chiral probes (chiral compounds). However, the influences, e.g. pH value, ionic strength, surface orientation etc., were found to affect significantly the enantiospecificity. Beside planar substrates, porous membranes (e.g. PTFE) were modified using chiral PEM and successfully applied in enantiospecific permeation. Additionally, protein binding properties of PEC particle dispersions or PEC particle films were also studied. Due to the properties of polyelectrolytes used for PEC (e.g. molecular weight, charge density) and proteins (e.g. isoelectric point, size, hydrophobicity), PEC showed different uptake characteristics towards different proteins. Electrostatic and hydrophobic interaction as well as counterion release force were considered as possible driving forces for protein b.
Download or read book Polyelectrolytes and Nanoparticles written by Joachim Koetz and published by Springer Science & Business Media. This book was released on 2007-02-20 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This lab manual guides chemists through demonstrations of synergistic effects between polyelectrolytes and nanoparticles. After a short introduction into the field of polyelectrolytes and polyelectrolyte characterization, the book discusses the role of polyelectrolytes in the process of nanoparticle formation. The book also explains methods for characterization of the polyelectrolyte-modified nanoparticles.
Download or read book Dispersed and Deposited Polyelectrolyte Complexes and Their Interactions to Chiral Compounds and Proteins written by Wuye Ouyang and published by . This book was released on 2009 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Compositions and Viscoelastic Properties in Solid Polyelectrolyte Complexes written by Yuhui Chen and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyelectrolytes are polymers bearing charged repeat units. Based on the charge, a polyelectrolyte can be categorized as either a polycation or a polyanion. When dissolved in water, the charges on a polyelectrolyte are balanced by small counterions. Mixing certain polycations and polyanions in an aqueous solution will result in solid precipitants due to polymer-polymer interactions and the entropy gain of releasing the small counterions. This type of material is called polyelectrolyte complexes, PECs. PECs have a wide range of applications including drug delivery systems, film coatings, and membranes. Because of their charged nature, PECs can bind with enzymes and DNA or many bio-medical applications. To further explore the applications of PECs, it is important to understand the dynamics and viscoelastic properties of this special type of polymer. Many factors such as water, temperature, and composition heavily influence the behaviors of PECs, and therefore were studied in this work.The first part of the dissertation focuses on water and the viscoelastic properties of various PECs. Thirteen different polyelectrolytes were used to produce those PECs, and radiolabeling and NMR techniques were used to determine the polycation: polyanion stoichiometry in the materials. Rheological studies were performed on those PECs to determine their glass transition temperatures, Tg. The PECs exhibit a wide range of Tgs within the working range of aqueous solutions between 0 and 100 °C. To study the correlation between Tg and water, a radiochemical method was developed to measure the pore volume within the PECs, which was used to differentiate between PEC water and pore water. Contrary to what was generally believed, the Tg correlated poorly with the water volume fraction in PECs. There was a weak correlation in a series of PECs in which one of the polyelectrolytes was held constant. On the other hand, time-temperature superposition of linear viscoelastic responses provided a classical estimate of the fractional free volume of PECs, which correlated well with Tg. The second part investigated the correlation between the stoichiometry and viscoelastic properties of a certain PEC, poly(diallydimethylammonium) (PDADMA)/poly(4-styrenesulfonic acid) (PSS). Various nonstoichiometric PECs with excess in either PDADMA or PSS were produced by a "quenching" method. A xvi maximum of 36% molar excess of PDADMA or 40% molar excess of PSS was achieved. Those nonstoichiometric PECs exhibited lower Tgs compared to stoichiometric ones, and an excess of PDADMA had a bigger effect on lowering the Tg. It was shown that the decrease in Tg was caused by the increase in water content. Due to the excess polyelectrolytes and counterions, more water was introduced to the nonstoichiometric PECs and therefore lowered the Tg via the plasticizing effect. In addition, time-temperature superposition revealed a correlation between segmental relaxation times and stoichiometry. Nonstoichiometric PECs were shown to have elevated fractional free volumes and decreased polymer volume fractions, which are responsible for changes in their mechanical properties. The third part focuses on the formation and properties of PEC blends. Four PECs with distinct Tgs were used to produce two PEC blends with varying compositions. Each blend is comprised of one polycation and two polyanions, and the molar ratio of the two polyanions was adjusted to create blends with the same components but different molar compositions. Rheological experiments were carried out to determine the Tgs of the blends. It was shown that one of the blends exhibited Tgs in between the two individual PECs, and the Tgs can be modeled using the Kwei Equation. The other blend showed two different Tgs that were similar to the individual PECs' Tgs, indicating the blend was immiscible. The immiscibility was explained by the difference in critical salt concentration between the two individual PECs.
