Download or read book Application of Systematic Review Methods in an Overall Strategy for Evaluating Low Dose Toxicity from Endocrine Active Chemicals written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-08-14 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: To safeguard public health, the US Environmental Protection Agency (EPA) must keep abreast of new scientific information and emerging technologies so that it can apply them to regulatory decision-making. For decades the agency has dealt with questions about what animal-testing data to use to make predictions about human health hazards, how to perform dose-response extrapolations, how to identify and protect susceptible subpopulations, and how to address uncertainties. As alternatives to traditional toxicity testing have emerged, the agency has been faced with additional questions about how to incorporate data from such tests into its chemical assessments and whether such tests can replace some traditional testing methods. Endocrine active chemicals (EACs) have raised concerns that traditional toxicity-testing protocols might be inadequate to identify all potential hazards to human health because they have the ability to modulate normal hormone function, and small alterations in hormone concentrations, particularly during sensitive life stages, can have lasting and significant effects. To address concerns about potential human health effects from EACs at low doses, this report develops a strategy to evaluate the evidence for such low-dose effects.

Download or read book Child specific Exposure Factors Handbook written by and published by . This book was released on 2002 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Toxicological Profile for Polybrominated Biphenyls and Polybrominated Diphenyl Ethers written by and published by . This book was released on 2004 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book New Types of Persistent Halogenated Compounds written by Jaakko Paasivirta and published by Springer. This book was released on 2008-01-26 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Chemistry is a relatively young science. Interest in this subject, however, is growing very rapidly and, although no agreement has been reached as yet about the exact content and limits of this interdisciplinary discipline, there appears to be increasing interest in seeing environmental topics which are based on chemistry embodied in this subject. One of the first objectives of Environ mental Chemistry must be the study of the environment and of natural chemical processes which occur in the environment. A major purpose of this series on Environmental Chemistry, therefore, is to present a reasonably uniform view of various aspects of the chemistry of the environment and chemical reactions occurring in the environment. The industrial activities of man have given a new dimension to Environ mental Chemistry. We have now synthesized and described over five million chemical compounds and chemical industry produces about hundred and fifty million tons of synthetic chemicals annually. We ship billions of tons of oil per year and through mining operations and other geophysical modifications, large quantities of inorganic and organic materials are released from their natural deposits. Cities and metropolitan areas of up to 15 million inhabitants produce large quantities of waste in relatively small and confined areas. Much of the chemical products and waste products of modern society are released into the environment either during production, storage, transport, use or ultimate disposal. These released materials participate in natural cycles and reactions and frequently lead to interference and disturbance of natural systems.

Download or read book Environmental Epigenetics in Toxicology and Public Health written by Rebecca Fry and published by Academic Press. This book was released on 2020-11-04 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Epigenetics in Toxicology and Public Health provides in-depth discussions of the suite of complex environmental factors shown to impact epigenetic components within the cell, as well as evidence that these epigenetic modifications are tied to early and later life health effects. This book offers a translational research perspective, highlighting both in vivo and human population-based evidence for ties between the environment, the epigenome, and health outcomes, with an emphasis on evidence for transgenerational effects of exposures, as well as developmental windows of susceptibility to environmentally-linked epigenetic effects. This volume in the Translational Epigenetics series aides in the development of new therapeutic options meant to reverse inappropriate epigenetic alterations, helping researchers in their efforts prevent and treat a variety of chronic diseases tied to environmental exposures. Offers a thorough discussion of the environmental factors influencing epigenetic mechanisms in early and late life, and in transgenerational inheritance Examines both animal model and human population-based research in environmental epigenetics, highlighting developmental windows of vulnerability to epigenetic modification Features contributions from international experts in the field

Download or read book Transport and Fate of Polybrominated Diphenyl Ethers in the Baltic and Arctic Regions written by Anna Palm and published by Nordic Council of Ministers. This book was released on 2004 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Polybrominated diphenyl ethers food contamination and potential risks report from a NNT group written by and published by Nordic Council of Ministers. This book was released on 1998 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book An Assessment of Polybrominated Diphenyl Ethers PBDEs in Sediments and Bivalves of the U S Coastal Zone written by K. L. Kimbrough and published by . This book was released on 2009 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report represents the first national assessment of PBDEs in the U.S. coastal zone. Results suggest that they are widely distributed nationally. Several regions, including the northern Mid-Atlantic, central Gulf of Mexico, Southern California, Pacific Northwest and the Great lakes have elevated PBDE concentrations compared with other coastal regions. Furthermore, PBDE concentrations are positively correlated with human population density along the U.S. coastline. The national and regional perspectives provided herein are intended to support research, local monitoring, and to assist resource managers and policy makers tasked with making regulatory decisions about these contaminants.

Download or read book Reviews of Environmental Contamination and Toxicology written by George W. Ware and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews of Environmental Contamination and Toxicology provides detailed review articles concerned with aspects of chemical contaminants, including pesticides, in the total environment with toxicological considerations and consequences.

Download or read book Determination of Polybrominated Diphenyl Ethers PBDEs in Sediment and Biota written by L. Webster and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fast Facts written by and published by . This book was released on 2010 with total page 3 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Advances in Sustainable and Environmental Hydrology Hydrogeology Hydrochemistry and Water Resources written by Helder I. Chaminé and published by Springer. This book was released on 2019-03-14 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprises the selected papers from the 1st Springer Conference of the Arabian Journal of Geosciences (CAJG-1), Tunisia 2018. The volume is of interest to all researchers and practitioners in the fields of Hydrology, Hydrogeology, Hydrochemistry, Water Resources and Hydrologic Engineering. Water is a dynamic, finite, and vulnerable but resilient natural resource to be protected in an environmentally sustainable manner. Water systems in different frameworks requires a comprehensive understanding of climatology, geology, hydrogeology, hydrochemistry, hydrodynamics, and surface hydrology. In addition, it is highlighted the role of the variability and climate change in water systems. Furthermore, water has a vital significance to the entire socio-economic sector. This volume offers an overview of the state-of-the-art related to water science and technology in model regions in Europe, Africa, Middle East, Asia and America, but mainly focuses on the Mediterranean environment and surrounding regions. It gives new insights on characterisation, evaluation, quality, management, protection, modelling on environmental hydrology, groundwater, hydrochemistry, sustainable water resources studies and hydrologic engineering approaches by international researchers. Main topics include: 1. Hydrology, Climatology and Water-Related Ecosystems 2. Hydrochemistry and Isotopic Hydrology 3. Groundwater Assessment and Management: mapping, exploration, abstraction and modelling 4. Water Resources Sustainability and Climate Change 5. Hydrologic Engineering and Urban Groundwater

Download or read book Comprehensive Sampling and Sample Preparation written by Josep M. Bayona and published by Academic Press. This book was released on 2012-12-31 with total page 2998 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Sampling and Sample Preparation is a complete treatment of the theory and methodology of sampling in all physical phases and the theory of sample preparation for all major extraction techniques. It is the perfect starting point for researchers and students to design and implement their experiments and support those experiments with quality-reviewed background information. In its four volumes, fundamentals of sampling and sample preparation are reinforced through broad and detailed sections dealing with Biological and Medical, Environmental and Forensic, and Food and Beverage applications. The contributions are organized to reflect the way in which analytical chemists approach a problem. It is intended for a broad audience of analytical chemists, both educators and practitioners of the art and can assist in the preparation of courses as well in the selection of sampling and sample preparation techniques to address the challenges at hand. Above all, it is designed to be helpful in learning more about these topics, as well as to encourage an interest in sampling and sample preparation by outlining the present practice of the technology and by indicating research opportunities. Sampling and Sample preparation is a large and well-defined field in Analytical Chemistry, relevant for many application areas such as medicine, environmental science, biochemistry, pharmacology, geology, and food science. This work covers all these aspects and will be extremely useful to researchers and students, who can use it as a starting point to design and implement their experiments and for quality-reviewed background information There are limited resources that Educators can use to effectively teach the fundamental aspects of modern sample preparation technology. Comprehensive Sampling and Sample Preparation addresses this need, but focuses on the common principles of new developments in extraction technologies rather than the differences between techniques thus facilitating a more thorough understanding Provides a complete overview of the field. Not only will help to save time, it will also help to make correct assessments and avoid costly mistakes in sampling in the process Sample and sample preparation are integral parts of the analytical process but are often less considered and sometimes even completely disregarded in the available literature. To fill this gap, leading scientists have contributed 130 chapters, organized in 4 volumes, covering all modern aspects of sampling and liquid, solid phase and membrane extractions, as well as the challenges associated with different types of matrices in relevant application areas

Download or read book The Bioaccumulation of Polybrominated Diphenyl Ethers in a Lake Michigan Food Web written by Dana L. Barton and published by . This book was released on 2002 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Toxicological Risks of Selected Flame Retardant Chemicals written by National Research Council and published by National Academies Press. This book was released on 2000-07-06 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ignition of upholstered furniture by small open flames from matches, cigarette lighters, and candles is one of the leading causes of residential-fire deaths in the United States. These fires accounted for about 16% of civilian fire deaths in 1996. On average, each year since 1990, about 90 deaths (primarily of children), 440 injuries, and property losses amounting to 50 million dollars have resulted from fires caused by the ignition of upholstered furniture by small open flames. Certain commercial seating products (such as aircraft and bus seats) are subject to flammability standards and sometimes incorporate FR-treated upholstery cover materials, but there is no federal-government requirement for residential upholstered furniture, and it is generally not treated with FR chemicals. It is estimated that less than 0.2% of all U.S. residential upholstery fabric is treated with flame-retardant (FR) chemicals. The Consumer Product Safety Act of 1972 created the U.S. Consumer Product Safety Commission (CPSC) as an independent federal regulatory agency whose mission is to protect the public from unreasonable risks of injury and death associated with consumer products. CPSC also administers the Flammable Fabrics Act, under which it regulates flammability hazards and the Federal Hazardous Substances Act (FHSA), which regulates hazardous substances including chemicals. In 1993, the National Association of State Fire Marshals petitioned CPSC to issue a performance-based flammability standard for upholstered furniture to reduce the risk of residential fires. The Commission granted that portion of the petition relating to small open flame ignition risks. In response to concerns regarding the safety of FR chemicals, Congress, in the fiscal year 1999 appropriations report for CPSC, requested that the National Research Council conduct an independent study of the health risks to consumers posed by exposure to FR chemicals that are likely to be used in residential upholstered furniture to meet a CPSC standard. The National Research Council assigned the project to the Committee on Toxicology (COT) of the Commission on Life Sciences' Board on Environmental Studies and Toxicology. COT convened the Subcommittee on Flame-Retardant Chemicals, which prepared this report. Subcommittee members were chosen for their recognized expertise in toxicology, pharmacology, epidemiology, chemistry, exposure assessment, risk assessment, and biostatistics. Toxicological Risks of Selected Flame-Retardant Chemicals is organized into 18 chapters and two appendices. Chapter 2 describes the risk assessment process used by the subcommittee in determining the risk associated with potential exposure to the various FR chemicals. Chapter 3 describes the method the subcommittee used to measure and estimate the intensity, frequency, extent, and duration of human exposure to FR chemicals. Chapters 4-19 provide the subcommittee's review and assessment of health risks posed by exposure to each of the 16 FR chemicals. Data gaps and research needs are provided at the end of these chapters.

Download or read book Toxicological Profile for Polybrominated Diphenyl Ethers PBDEs written by and published by . This book was released on 2017 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Encyclopedia of Environmental Health written by and published by Elsevier. This book was released on 2019-08-22 with total page 4896 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Environmental Health, Second Edition, Six Volume Set presents the newest release in this fundamental reference that updates and broadens the umbrella of environmental health, especially social and environmental health for its readers. There is ongoing revolution in governance, policies and intervention strategies aimed at evolving changes in health disparities, disease burden, trans-boundary transport and health hazards. This new edition reflects these realities, mapping new directions in the field that include how to minimize threats and develop new scientific paradigms that address emerging local, national and global environmental concerns. Represents a one-stop resource for scientifically reliable information on environmental health Fills a critical gap, with information on one of the most rapidly growing scientific fields of our time Provides comparative approaches to environmental health practice and research in different countries and regions of the world Covers issues behind specific questions and describes the best available scientific methods for environmental risk assessment