Download or read book Animal Toxins written by Hervé Rochat and published by Springer Science & Business Media. This book was released on 2000 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural toxins form a major component of the molecular tools used increasingly frequently by the ever growing number of laboratories of various kinds. Evidence for this is provided not only by the increasing number of firms including such toxins in their catalogues but also by the large number of demands received by those who discover new toxins. Twenty chapters survey important aspects of toxin origin, their structure and molecular mechanism, and their cellular and pathogenic effects. In addition, the text provides comprehensive and specific methodology for the application of these toxins in the research laboratory. This begins with the description of the method of extraction, biochemical and pharmacological characterization, and assessment of purity, and continues with methods for chemical modification, e.g. labelling, and eventually describes applications in pharmacological studies in vivo and/or in vitro. The length of this book has been kept reasonable by concentrating on...

Download or read book Mastering the Information Age Solving Problems with Visual Analytics written by Daniel A. Keim and published by Florian Mansmann. This book was released on 2010 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Biological Threat Reduction Program of the Department of Defense written by National Research Council and published by National Academies Press. This book was released on 2007-10-10 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Congressionally-mandated report identifies areas for further cooperation with Russia and other states of the former Soviet Union under the Cooperative Threat Reduction (CTR) program of the Department of Defense in the specific area of prevention of proliferation of biological weapons. The report reviews relevant U.S. government programs, and particularly the CTR program, and identifies approaches for overcoming obstacles to cooperation and for increasing the long-term impact of the program. It recommends strong support for continuation of the CTR program.

Download or read book A Guide to Human Gene Therapy written by Roland W. Herzog and published by World Scientific. This book was released on 2010 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Non-viral gene therapy / Sean M. Sullivan -- 2. Adenoviral vectors / Stuart A. Nicklin and Andrew H. Baker -- 3. Retroviral vectors and integration analysis / Cynthia C. Bartholomae [und weitere] -- 4. Lentiviral vectors / Janka Matrai, Marinee K.L. Chuah and Thierry VandenDriessche -- 5. Herpes simplex virus vectors / William F. Goins [und weitere] -- 6. Adeno-Associated Viral (AAV) vectors / Nicholas Muzyczka -- 7. Regulatory RNA in gene therapy / Alfred. S. Lewin -- 8. DNA integrating vectors (Transposon, Integrase) / Lauren E. Woodard and Michele P. Calos -- 9. Homologous recombination and targeted gene modification for gene therapy / Matthew Porteus -- 10. Gene switches for pre-clinical studies in gene therapy / Caroline Le Guiner [und weitere] -- 11. Gene therapy for central nervous system disorders / Deborah Young and Patricia A. Lawlor -- 12. Gene therapy of hemoglobinopathies / Angela E. Rivers and Arun Srivastava -- 13. Gene therapy for primary immunodeficiencies / Aisha Sauer, Barbara Cassani and Alessandro Aiuti -- 14. Gene therapy for hemophilia / David Markusic, Babak Moghimi and Roland Herzog -- 15. Gene therapy for obesity and diabetes / Sergei Zolotukhin and Clive H. Wasserfall -- 16. Gene therapy for Duchenne muscular dystrophy / Takashi Okada and Shin'ichi Takeda -- 17. Cancer gene therapy / Kirsten A.K. Weigel-Van Aken -- 18. Gene therapy for autoimmune disorders / Daniel F. Gaddy, Melanie A. Ruffner and Paul D. Robbins -- 19. Gene therapy for inherited metabolic storage diseases / Cathryn Mah -- 20. Retinal diseases / Shannon E. Boye, Sanford L. Boye and William W. Hauswirth -- 21. A brief guide to gene therapy treatments for pulmonary diseases / Ashley T. Martino, Christian Mueller and Terence R. Flotte -- 22. Cardiovascular disease / Darin J. Falk, Cathryn S. Mah and Barry J. Byrne

Download or read book Lithium ion Batteries written by and published by . This book was released on 2019 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is the first machine-generated scientific book in chemistry published by Springer Nature. Serving as an innovative prototype defining the current status of the technology, it also provides an overview about the latest trends of lithium-ion batteries research. This book explores future ways of informing researchers and professionals. State-of-the-art computer algorithms were applied to: select relevant sources from Springer Nature publications, arrange these in a topical order, and provide succinct summaries of these articles. The result is a cross-corpora auto-summarization of current texts, organized by means of a similarity-based clustering routine in coherent chapters and sections. This book summarizes more than 150 research articles published from 2016 to 2018 and provides an informative and concise overview of recent research into anode and cathode materials as well as further aspects such as separators, polymer electrolytes, thermal behavior and modelling. With this prototype, Springer Nature has begun an innovative journey to explore the field of machine-generated content and to find answers to the manifold questions on this fascinating topic. Therefore it was intentionally decided not to manually polish or copy-edit any of the texts so as to highlight the current status and remaining boundaries of machine-generated content. Our goal is to initiate a broad discussion, together with the research community and domain experts, about the future opportunities, challenges and limitations of this technology."--Publisher's website.

Download or read book Analysis and Application of Analog Electronic Circuits to Biomedical Instrumentation written by Robert B. Northrop and published by CRC Press. This book was released on 2003-12-29 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the basic mathematical tools used to describe noise and its propagation through linear systems and provides a basic description of the improvement of signal-to-noise ratio by signal averaging and linear filtering. The text also demonstrates how op amps are the keystone of modern analog signal conditioning systems design, and il

Download or read book Energy Research Abstracts written by and published by . This book was released on 1981 with total page 1634 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chemical Kinetics written by Luis Arnaut and published by Elsevier. This book was released on 2006-12-21 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Kinetics bridges the gap between beginner and specialist with a path that leads the reader from the phenomenological approach to the rates of chemical reactions to the state-of-the-art calculation of the rate constants of the most prevalent reactions: atom transfers, catalysis, proton transfers, substitution reactions, energy transfers and electron transfers. For the beginner provides the basics: the simplest concepts, the fundamental experiments, and the underlying theories. For the specialist shows where sophisticated experimental and theoretical methods combine to offer a panorama of time-dependent molecular phenomena connected by a new rational. Chemical Kinetics goes far beyond the qualitative description: with the guidance of theory, the path becomes a reaction path that can actually be inspected and calculated. But Chemical Kinetics is more about structure and reactivity than numbers and calculations. A great emphasis in the clarity of the concepts is achieved by illustrating all the theories and mechanisms with recent examples, some of them described with sufficient detail and simplicity to be used in general chemistry and lab courses.* Looking at atoms and molecules, and how molecular structures change with time. * Providing practical examples and detailed theoretical calculations* Of special interest to Industrial Chemistry and Biochemistry

Download or read book Diagnostic Cytogenetics written by Rolf-Dieter Wegner and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following a section on tissue culture, chromosome staining and basic information about karyotyping, this text presents nomenclature and quality standards, as well as protocols of relevance to comprehensive cytogenetic diagnostics.

Download or read book The olivo cerebellar system written by Egidio D'Angelo and published by Frontiers Media SA. This book was released on 2016-04-29 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last decades, investigations on the olivo-cerebellar system have attained a high level of sophistication, which led to redefinitions of several structural and functional properties of neurons, synapses, connections and circuits. Research has expanded and deepened in so many directions and so many theories and models have been proposed that an ensemble review of the matter is now needed. Yet, hot topics remain open and scientific discussion is very lively at several fronts. One major question, here as well as in other major brain circuits, is how single neurons and synaptic properties emerge at the network level and contribute to behavioural regulation via neuronal plasticity. Other major aspects that this Research Topic covers and discusses include the development and circuit organization of the olivo-cerebellar network, the established and recent theories of learning and motor control, and the emerging role of the cerebellum in cognitive processing. By touching on such varied and encompassing subjects, this Frontiers Special Topic aims to highlight the state of the art and stimulate future research. We hope that this unique collection of high-quality articles from experts in the field will provide scientists with a powerful basis of knowledge and inspiration to enucleate the major issues deserving further attention.

Download or read book Climate Change Vulnerability and Adaptation in Asia and the Pacific written by Lin Erda and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: PREFACE ix ACKNOWLEDGMENTS xi L. AMADORE, W. C. BOLHOFER, R. V. CRUZ, R. B. FEIR, C. A. FREYSINGER, S. GUILL, K. F. JALAL, A IGLESIAS, A. JOSE, S. LEATHERMAN, S. LENHART, S. MUKHER JEE, J. B. SMITH, and J. WISNIEWSKII Climate Change Vulnerability and Adap tion in Asia and the Pacific: Workshop Summary 1-12 A. IGLESIAS, LlN ERDA, and C. ROSENZWEIG I Climate Change in Asia: A Review of the Vulnerability and Adaption of Crop Production 13-27 I. AMIEN, P. REJEKININGRUM, A. PRAMUDIA, and E. SUSANTII Effects of Interannual Climate Variability and Climate Change on Rice Yield in Java, Indonesia 29-39 R. D. BUAN, AR. MAGLlNAO, P. P. EVANGELISTA, and B. G. PAJUELAS I Vulnerability of Rice and Corn to Climate Change in the Philippines 41-51 Z. KARIM, S. G. HUSSAIN, and M. AHMED I Assessing Impacts of Climatic Variations on Foodgrain Production in Bangladesh 53-62 LlN ERDA I Agricultural Vulnerability and Adaptation to Global Warming in China 63-73 WANG JINGHUA and LlN ERDA I The Impacts of Potential Climate Change and Climate Variability on Simulated Maize Production in China 75-85 M. A. WIJERATNE I Vulnerability of Sri Lanka Tea Production to Global Climate Change 87-94 B. BOLORTSETSEG and G. TUVAANSUREN I The Potential Impacts of Climate Change on Pasture and Cattle Production in Mongolia 95-105 K. BOONPRAGOB and J. SANTISIRISOMBOON I Modeling Potential Changes of Forest Area in Thailand under Climate Change 107-117 K. 1. KOBAK, I. YE. TURCHINOVICH, N. YU. KONDRASHEVA, E. -D. SCHULZE, W.

Download or read book Epoxy Resins Curing Agents Compounds and Modifiers written by Ernest W. Flick and published by William Andrew. This book was released on 2012-12-02 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this popular industrial guide describes over 2,800 currently available epoxy resins, curing agents, compounds, and modifiers, based on information supplied by 71 manufacturers or distributors of these products. Epoxy resins have experienced tremendous growth since their introduction in the 1950s. Future growth will be in new markets in the specialty performance areas and high-technology applications. Each raw material or product is described, as available, with typical assay or checkpoint figures and a brief summary of important features or applications. Additional sections useful to the reader are the Suppliers' Addresses and a Trade Name Index.

Download or read book Plant Tissue Culture Manual Supplement 7 written by K. Lindsey and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant tissue culture has a long history, dating back to the work of Gottlieb Haberlandt and others at the end of the 19th century, but the associated concepts and techniques have reached a level of usefulness and application which has never been greater. The technical innovations have given new insights into fundamental aspects of plant differentiation and development, and have paved the way to the identification of strategies for the genetic manipula tion of plants. It is the aim of this manual to deliver a broad range of these techniques in a form which is accessible to students and research scientists of diverse backgrounds, including those with little or no previous experience. The themes of the manual aim to reflect those research areas which have been advanced by tissue culture technology. As was the case for the sister volume Plant Molecular Biology Manual, the objective has been from the start to produce a manual which is at home on the laboratory bench. The plastic-covered, ring-bound format has proved to be most popular and is retained here. Equally, the emphasis has been on producing a collection of detailed step-by-step protocols, each supplemented with an introductory text and practical footnotes, to provide the next best thing to a supervisor at one's shoulder.

Download or read book International Transistor Equivalents Guide written by Adrian Michaels and published by . This book was released on 1981 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Zeta Potential in Colloid Science written by Robert J. Hunter and published by Academic Press. This book was released on 2013-09-03 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zeta Potential in Colloid Science: Principles and Applications covers the concept of the zeta potential in colloid chemical theory. The book discusses the charge and potential distribution at interfaces; the calculation of the zeta potential; and the experimental techniques used in the measurement of electrokinetic parameters. The text also describes the electroviscous and viscoelectric effects; applications of the zeta potential to areas of colloid science; and the influence of simple inorganic ions or more complex adsorbates on zeta potential. Physical chemists and people involved in the study of colloid science will find the book useful.

Download or read book Biofilms Infection and Antimicrobial Therapy written by John L Pace and published by CRC Press. This book was released on 2019-08-30 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rather than existing in a planktonic or free-living form, evidence indicates that microbes show a preference for living in a sessile form within complex communities called biofilms. Biofilms appear to afford microbes a survival advantage by optimizing nutrition, offering protection against hostile elements, and providing a network for cell-to-cell signaling and genetic exchange. Biofilms, Infection, and Antimicrobial Therapy provides an in-depth exploration of biofilms, offering broad background information, as well a detailed look at the serious concerns to which biofilm-associated infections give rise. Prosthetic device infections, such as those involving artificial heart valves, intravascular catheters, or prosthetic joints, are prime examples of biofilm-associated infections. With the increasing use of such devices in the modern practice of medicine, the prevalence of these infections is expected to increase. Unfortunately, one of the most troubling characteristics of microbes found in biofilms is a profound resistance to antimicrobial agents. As biofilm-associated infections are particularly difficult to treat, they result in significant mortality, morbidity, and increased economic burden. Clearly, a better understanding of the pathogenesis of these infections and improved means for prevention and treatment are urgently needed! InBiofilms, Infection, and Antimicrobial Therapy, Drs Pace, Rupp, and Finch assemble the contributions of more than 50 of the world's leading authorities on microbial biofilms who present recent findings on antibacterial tolerance and bacterial persistence associated with biofilms and discuses the implications of those findings with regard to human health. They explore the molecular mechanisms of bacterial adherence, biofilm formation, regulation of biofilm maintenance, and cell-to-cell communication and present the latest information on various treatment protocols that should aid physicians in the treatment o

Download or read book Broadband Islands towards Integration written by Otto Spaniol and published by . This book was released on 1993 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Different topics related to European research policy and funding in the area of broadband communications are explored in this volume. Consideration is given both to the obvious scientific aspects and to the political/strategic dimension accorded by its RACE context. Five major sections form the bulk of the book. The first provides a survey of what is currently happening in the area of very high speed communication. The application issue is reinforced by the next part, where market trends are addressed as well as upcoming applications for very high speed networks. The third chapter is broad ranging and includes an examination of architectures from workstations via QoS and domain management to multimedia documents. The upper layers of the OSI/RM are addressed in the fourth section, with the typical problems arising if multimedia information is to be transmitted and processed forming the core of the discussion. The following chapter considers the lower layers' issues.These 5 major sections are followed by some 12 papers considering a diverse range of topics. A discussion on Exploiting the Changing Telecommunications Market: Where can Europe Succeed? concludes the volume. It attempts to identify both Europe's current position and its future prospects in this rapidly developing market - with a firm recommendation that the three major players, Europe, the USA and Japan will have to join forces.