Download or read book Structural and Biological Applications of Schiff Base Metal Complexes written by Pallavi Jain and published by CRC Press. This book was released on 2023-05-31 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coordination compounds have been well-known for their wide variety of applications for over a century, as well as enhancing the researcher’s interest and concern in evaluating their action mechanism. It is certainly one of the most intensely discussed research topics. Coordination compounds involve different metal-ion-ligand phenomenon. The involved metal ions play a significant role in structural association and functioning of several processes in the genetic and metabolism system. In recent years, Schiff base ligands have gained significant interest and received a keen interest of many researchers. Schiff’s base ligands have been recognized to hold a wide variety of biological and medicinal activities due to the presence of donor atoms. They have proved exceptional pharmalogical actions such as antimicrobial, anti-tuberclosis, antiplatelet, antidiabetic, antiarthritis, antioxidant, anti-inflammatory, anticancer, antiviral, antimalarial, and analgesic. These biologically active Schiff base ligands have also been shown to inhibit enzyme mobilization and, when bound to a metal ion, exhibit enhanced biological activity, making them useful in a number of fields. As a result, metal complexes of Schiff base ligands are gaining popularity due to their unique properties and functionalities. Schiff base complex-based research for educational and industrial purposes is booming, and the number of publications is gradually increasing. Despite these interests, there is currently no detailed book on Schiff base metal complexes that covers the structures, biological activities, and other non-biological perspectives. This book delves into the structures of Schiff base metal complexes, which are critical in assessing the biological viability of any complex. It also highlights their biological significance in pharma and drug discovery like antibacterial, antifungal, anticancer, anti-inflammatory, anti-arthritis, anti-diabetic, antioxidants, anti-proliferative, antitumor, anticancer, antiviral. The fundamentals of metal complexes are described, as well as an up-to-date outline of developments in synthesis, characterization methods, properties- chemical, thermal, optical, structural, and applications. This book also discusses the other applications of Schiff base metal complexes: as sensor (luminescent, electrochemical, and biosensor), as pigments in dying and paint industries, as photocatalyst to improve the degradation rate. Features : This book would be useful for academia, researchers and engineers working in the area of Schiff base and their metal complexes. This book will give an in-depth account of the properties of Schiff base and their metal complexes. This book will discuss the details of synthesis methods for Schiff base and their metal complexes. This book will cover emerging trends in the use of Schiff base metal complexes in the industry. This book will provide an overview of the wider biological applications of Schiff base metal complexes

Download or read book Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards written by and published by . This book was released on 1994 with total page 1036 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theses on any subject submitted by the academic libraries in the UK and Ireland.

Download or read book Ligand Design in Medicinal Inorganic Chemistry written by Tim Storr and published by John Wiley & Sons. This book was released on 2014-06-12 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing the potency of therapeutic compounds, while limiting side-effects, is a common goal in medicinal chemistry. Ligands that effectively bind metal ions and also include specific features to enhance targeting, reporting, and overall efficacy are driving innovation in areas of disease diagnosis and therapy. Ligand Design in Medicinal Inorganic Chemistry presents the state-of-the-art in ligand design for medicinal inorganic chemistry applications. Each individual chapter describes and explores the application of compounds that either target a disease site, or are activated by a disease-specific biological process. Ligand design is discussed in the following areas: Platinum, Ruthenium, and Gold-containing anticancer agents Emissive metal-based optical probes Metal-based antimalarial agents Metal overload disorders Modulation of metal-protein interactions in neurodegenerative diseases Photoactivatable metal complexes and their use in biology and medicine Radiodiagnostic agents and Magnetic Resonance Imaging (MRI) agents Carbohydrate-containing ligands and Schiff-base ligands in Medicinal Inorganic Chemistry Metalloprotein inhibitors Ligand Design in Medicinal Inorganic Chemistry provides graduate students, industrial chemists and academic researchers with a launching pad for new research in medicinal chemistry.

Download or read book Index to Theses Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards written by and published by . This book was released on 1977 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Indian Science Abstracts written by and published by . This book was released on 1994 with total page 924 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Polymers for Biomedical Applications written by Anil Mahapatro and published by American Chemical Society. This book was released on 2008-04-17 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on applications of polymers for biomedical applications has increased dramatically to find improved medical plastics for this rapidly evolving field. This book brings together various aspects of recent research and developments within academia and industry related to polymers for biomedical applications.

Download or read book Enzyme Chemistry written by Colin Suckling and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the first edition of this book was going through the publication process, a revolution was taking place in the technologies available for the study of enzymes. The techniques of molecular biology, especially in genetic engineering of organisms and in site specific mutagenesis of genes, were established and were being brought into use to solve many problems in in enzymology. Added to these fundamental and applied science, not least advances the possibility of generating catalysts from antibodies has become a topic of major interest. These major innovations have changed the emphasis of much bioorganic research; whereas in the past, the protein was often the 'sleeping partner' ina study, its detailed function is now the major focus of scientific interest. Similarly in industry, the potential of genetically manipulated organisms to satisfy the needs for the production of chemicals and foodstuffs has been widely recognised. The second edition of 'Enzyme Chemistry, Impact and Applications' takes on board these new develop ments whilst maintaining the overall aims and views of the first edition. Many of the chapters have been completely rewritten to take account of advances in the last five years especially with regard to the impact of biologically based technologies. Although the book continues to approach its subject matter from the point of view of the chemist, the increased interdisciplinary content of much modern science will be obvious from the discussion.

Download or read book Chemistry of Polymeric Metal Chelates written by Gulzhian I. Dzhardimalieva and published by Springer. This book was released on 2018-02-13 with total page 1036 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the chemistry of polymeric metal chelates. The main results and the production and chemical structure of polymers with chelate units as well as the specificity of metal complex binding of different structure are presented here. This book also reveals the transformations which components undergo in the course of chelation. Special attention is paid not only to synthetic but also to natural (including living) systems. The usage of polymeric metal chelates and their development are examined. The related research was performed for chelates with chain structure. This book is useful to researchers being active in synthesis and design of macromolecular metal chelates

Download or read book Chelation Therapy in the Treatment of Metal Intoxication written by Jan Aaseth and published by Academic Press. This book was released on 2016-04-18 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chelation Therapy in the Treatment of Metal Intoxication presents a practical guide to the use of chelation therapy, from its basic chemistry, to available chelating antidotes, and the application of chelating agents. Several metals have long been known to be toxic to humans, and continue to pose great difficulty to treat. These challenges pose particular problems in industrial settings, with lead smelting known to be associated with hemopoietic alterations and paralyses, and the inhalation of mercury vapor in mercury mining being extremely detrimental to the central nervous system. Clinical experience has demonstrated that acute and chronic human intoxications with a range of metals can be treated efficiently by administration of chelating agents. Chelation Therapy in the Treatment of Metal Intoxication describes the chemical and biological principles of chelation in the treatment of these toxic metal compounds, including new chelators such as meso-2,3-dimercaptosuccinic acid (DMSA) and D,L-2,3-dimercapto-1-propanesulfonic acid (DMPS). - Presents all the current findings on the potential for chelation as a therapy for metal intoxication - Presents practical guidelines for selecting the most appropriate chelating agent - Includes coverage on radionuclide exposure and metal storage diseases - Describes the chemical and biological principles of chelation in the treatment of toxic metal compounds

Download or read book Metal based Anticancer Agents written by Angela Casini and published by Royal Society of Chemistry. This book was released on 2019-04-05 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compounds to patients. Metal-based Anticancer Agents covers the interdisciplinary world of inorganic drug discovery and development by introducing the most prominent compound classes based on different transition metals, discussing emerging concepts and enabling methods, as well as presenting key pre-clinical and clinical aspects. Recent progress on the unique features of next-generation targeted metal-based anticancer agents, including supramolecular coordination complexes used for both therapy and drug delivery, promise a bright future beyond the benefits of pure cytotoxic activity. With contributions from global leaders in the field, this book will serve as a useful reference to established researchers as well as a practical guide to those new to metallodrugs, and postgraduate students of medicinal chemistry and metallobiology.

Download or read book Quarterly Journal of the Chemical Society of London written by Chemical Society (Great Britain) and published by . This book was released on 1971 with total page 1020 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Supramolecular Chemistry in the 3rd Millennium written by Catherine E. Housecroft and published by MDPI. This book was released on 2021-08-18 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue is one of the first for the new MDPI flagship journal Chemistry (ISSN 2624-8549) which has a broad remit for publishing original research in all areas of chemistry. The theme of this issue is Supramolecular Chemistry in the 3rd Millennium and I am sure that this topic will attract many exciting contributions. We chose this topic because it encompasses the unity of contemporary pluridisciplinary science, in which organic, inorganic, physical and theoretical chemists work together with molecular biologists and physicists to develop a systems-level understanding of molecular interactions. The description of supramolecular chemistry as 'chemistry beyond the molecule' (Jean-Marie Lehn, Nobel Lecture and Gautam R. Desiraju, Nature, 2001, 412, 397) addresses the wide variety of weak, non-covalent interactions that are the basis for the assembly of supramolecular architectures, molecular receptors and molecular recognition, programed molecular systems, dynamic combinatorial libraries, coordination networks and functional supramolecular materials. We welcome submissions from all disciplines involved in this exciting and evolving area of science.

Download or read book Luminescent and Photoactive Transition Metal Complexes as Biomolecular Probes and Cellular Reagents written by Kenneth Kam-Wing Lo and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding. The scope of the series spans the entire Periodic Table and addresses structure and bonding issues associated with all of the elements. It also focuses attention on new and developing areas of modern structural and theoretical chemistry such as nanostructures, molecular electronics, designed molecular solids, surfaces, metal clusters and supramolecular structures. Physical and spectroscopic techniques used to determine, examine and model structures fall within the purview of Structure and Bonding to the extent that the focus is on the scientific results obtained and not on specialist information concerning the techniques themselves. Issues associated with the development of bonding models and generalizations that illuminate the reactivity pathways and rates of chemical processes are also relevant. The individual volumes in the series are thematic. The goal of each volume is to give the reader, whether at a university or in industry, a comprehensive overview of an area where new insights are emerging that are of interest to a larger scientific audience. Thus each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years should be presented using selected examples to illustrate the principles discussed. A description of the physical basis of the experimental techniques that have been used to provide the primary data may also be appropriate, if it has not been covered in detail elsewhere. The coverage need not be exhaustive in data, but should rather be conceptual, concentrating on the new principles being developed that will allow the reader, who is not a specialist in the area covered, to understand the data presented. Discussion of possible future research directions in the area is welcomed. Review articles for the individual volumes are invited by the volume editors. Readership: research scientists at universities or in industry, graduate students Special offer For all customers who have a standing order to the print version of Structure and Bonding, we offer free access to the electronic volumes of the Series published in the current year via SpringerLink.

Download or read book Metal Nanoparticles in Microbiology written by Mahendra Rai and published by Springer Science & Business Media. This book was released on 2011-04-02 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following an introduction to biogenic metal nanoparticles, this book presents how they can be biosynthesized using bacteria, fungi and yeast, as well as their potential applications in biomedicine. It is shown that the synthesis of nanoparticles using microbes is eco-friendly and results in reproducible metal nanoparticles of well-defined sizes, shapes and structures. This biotechnological approach based on the process of biomineralization exploits the effectiveness and flexibility of biological systems. Chapters include practical protocols for microbial synthesis of nanoparticles and microbial screening methods for isolating a specific nanoparticle producer as well as reviews on process optimization, industrial scale production, biomolecule-nanoparticle interactions, magnetosomes, silver nanoparticles and their numerous applications in medicine, and the application of gold nanoparticles in developing sensitive biosensors.

Download or read book Analytical Determination of Nicotine and Related Compounds and their Metabolites written by J.W. Gorrod and published by Elsevier. This book was released on 1999-11-02 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides for the first time a single comprehensive source of information on the analytical chemistry of nicotine and related alkaloids. The editors have brought together scientists from academia and the tobacco industry to describe the state-of-the-art of the chemistry and analytical methods for measurement of nicotine. Both the scope and detail of the book are impressive. Chapters describe the history, pharmacology and toxicology of nicotine, the biosynthesis of nicotine and other alkaloids in the tobacco plant, the general chemistry of nicotine and the analytical methodologies that have been used to measure nicotine and related alkaloids in biological specimens, in tobacco and pharmaceutical products and in tobacco smoke. There is also a comprehensive review of the chemistry and toxicology of nicotine-derived nitrosamines, an important class of tobacco carcinogens.

Download or read book Chemistry for Pharmacy Students written by Professor Satyajit D. Sarker and published by John Wiley & Sons. This book was released on 2013-05-28 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book has succeeded in covering the basic chemistry essentials required by the pharmaceutical science student... the undergraduate reader, be they chemist, biologist or pharmacist will find this an interesting and valuable read." –Journal of Chemical Biology, May 2009 Chemistry for Pharmacy Students is a student-friendly introduction to the key areas of chemistry required by all pharmacy and pharmaceutical science students. The book provides a comprehensive overview of the various areas of general, organic and natural products chemistry (in relation to drug molecules). Clearly structured to enhance student understanding, the book is divided into six clear sections. The book opens with an overview of general aspects of chemistry and their importance to modern life, with particular emphasis on medicinal applications. The text then moves on to a discussion of the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy- in relation to drug action and toxicity. Various aspects of aliphatic, aromatic and heterocyclic chemistry and their pharmaceutical importance are then covered with final chapters looking at organic reactions and their applications to drug discovery and development and natural products chemistry. accessible introduction to the key areas of chemistry required for all pharmacy degree courses student-friendly and written at a level suitable for non-chemistry students includes learning objectives at the beginning of each chapter focuses on the physical properties and actions of drug molecules

Download or read book Chemistry of Tin written by P.J. Smith and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: In common with the editor of the first edition, my own personal involvement with tin chemistry began when I had the privilege of studying for a PhD degree under the supervision of Professor Alwyn G. Davies FRS at University College London (UCL) almost exactly 30 years ago. Then, following 21 years' service with the International Tin Research Institute, it was a great pleasure for me when the wheel turned full circle and, in 1994, Alwyn - now an Emeritus Professor - asked me to return to UCL as an Honorary Research Fellow in the Chemistry Department. One of my first tasks was when I received an invitation from Blackie A&P to edit the second edition of the Chemistry of Tin, which I was delighted to accept, since it enabled me to continued my life-long interest in tin chemistry and to maintain contact with my former friends and colleagues, many of whom have contributed to this book.