Download or read book Plasma Confinement written by R. D. Hazeltine and published by Courier Corporation. This book was released on 2013-02-20 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Graduate-level text examines the essential physics underlying international research in magnetic confinement fusion with accounts of fundamental concepts behind methods of confining plasma at or near thermonuclear conditions. 1992 edition.
Download or read book Handbook on Plasma Instabilities written by Ferdinand F. Cap and published by Academic Press. This book was released on 2013-09-11 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook on Plasma Instabilities, Volume 2 consists of four chapters on plasma instabilities. Chapter 14 discusses the various aspects of microinstabilities. Beam-plasma systems are covered in Chapter 15, while the various stabilization methods are presented in Chapter 16. This book concludes with deliberations on parametric effects in Chapter 17. Other topics discussed include the microinstabilities of a homogeneous unmagnetized plasma; kinetic theory of macroscopic instabilities; basic beam physics; and beam-plasma instabilities. The magnetic field configuration stabilization; macroscopic nonmagnetic stabilization methods; parametric instabilities in homogeneous unmagnetized plasmas; and parametric effects in bounded and inhomogeneous plasmas are also elaborated in this text. This publication is beneficial to students and researchers conducting work on unstable plasma.
Download or read book Magnetohydrodynamic Stability of Tokamaks written by Hartmut Zohm and published by John Wiley & Sons. This book was released on 2015-02-09 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book bridges the gap between general plasma physics lectures and the real world problems in MHD stability. In order to support the understanding of concepts and their implication, it refers to real world problems such as toroidal mode coupling or nonlinear evolution in a conceptual and phenomenological approach. Detailed mathematical treatment will involve classical linear stability analysis and an outline of more recent concepts such as the ballooning formalism. The book is based on lectures that the author has given to Master and PhD students in Fusion Plasma Physics. Due its strong link to experimental results in MHD instabilities, the book is also of use to senior researchers in the field, i.e. experimental physicists and engineers in fusion reactor science. The volume is organized in three parts. It starts with an introduction to the MHD equations, a section on toroidal equilibrium (tokamak and stellarator), and on linear stability analysis. Starting from there, the ideal MHD stability of the tokamak configuration will be treated in the second part which is subdivided into current driven and pressure driven MHD. This includes many examples with reference to experimental results for important MHD instabilities such as kinks and their transformation to RWMs, infernal modes, peeling modes, ballooning modes and their relation to ELMs. Finally the coverage is completed by a chapter on resistive stability explaining reconnection and island formation. Again, examples from recent tokamak MHD such as sawteeth, CTMs, NTMs and their relation to disruptions are extensively discussed.
Download or read book NASA Thesaurus written by and published by . This book was released on 1988 with total page 884 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drug Like Properties written by Li Di and published by Academic Press. This book was released on 2015-12-17 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates. This valuable resource explores physiochemical properties, including solubility and permeability, before exploring how compounds are absorbed, distributed, and metabolized safely and stably. Review chapters provide context and underscore the importance of key concepts such as pharmacokinetics, toxicity, the blood-brain barrier, diagnosing drug limitations, prodrugs, and formulation. Building on those foundations, this thoroughly updated revision covers a wide variety of current methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties for process and product improvement. From conducting key assays for interpretation and structural analysis, the reader learns to implement modification methods and improve each ADME property. Through valuable case studies, structure-property relationship descriptions, and structure modification strategies, Drug-Like Properties, Second Edition, offers tools and methods for ADME/Tox scientists through all aspects of drug research, discovery, design, development, and optimization. - Provides a comprehensive and valuable working handbook for scientists and students in medicinal chemistry - Includes expanded coverage of pharmacokinetics fundamentals and effects - Contains updates throughout, including the authors' recent work in the importance of solubility in drug development; new and currently used property methods, with a reduction of seldom-used methods; and exploration of computational modeling methods
Download or read book Nuclear Science Abstracts written by and published by . This book was released on 1971-04 with total page 1658 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Applied Mechanics Reviews written by and published by . This book was released on 1978 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Energy Research Abstracts written by and published by . This book was released on 1990 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book TID written by and published by . This book was released on 1958 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Controlled Thermonuclear Processes written by Thomas W. Scott and published by . This book was released on 1958 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: A total of 126 annotated references to unclassified reports and journal articles in presented, covering research and development conducted in the United States in the field of controlled thermonuclear reactions. Author, subject, and report number indexes are included.
Download or read book Scientific and Technical Aerospace Reports written by and published by . This book was released on 1979 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drug like Properties Concepts Structure Design and Methods written by Li Di and published by Elsevier. This book was released on 2010-07-26 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. - Serves as an essential working handbook aimed at scientists and students in medicinal chemistry - Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies - Discusses improvements in pharmacokinetics from a practical chemist's standpoint
Download or read book Peptide Therapeutics written by Seetharama D. Jois and published by Springer Nature. This book was released on 2022-09-26 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains how peptide-based drug design works, what steps are needed to develop a peptide-based therapeutic, and challenges in synthesis as well as regulatory issues. It covers the design concept of peptide therapeutics from fundamental principles using structural biology and computational approaches. The chapters are arranged in a linear fashion. A fresh graduate or a scientist who works on small molecules can use this to follow the design and development of peptide therapeutics to use as understanding the basic concepts. Each chapter is written by experts from academia as well as industry. Rather than covering extensive literature, the book provides concepts of design, synthesis, delivery, as well as regulatory affairs and manufacturing of peptides in a systematic way with examples in each case. The book can be used as a reference for a pharmaceutical or biomedical scientist or graduate student who wants to pursue their career in peptide therapeutics. Some chapters will be written as a combination of basic principles and protocol so that scientists can adopt these methods to their research work. The examples provided can be used to perform peptide formulation considerations for the designed peptides. The book has nine chapters, and each chapter can be read as an independent unit on a particular concept.
Download or read book A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi and published by Academic Press. This book was released on 2016-11-03 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. - Provides unique content that is not always covered together in one comprehensive resource, including chapters on stem cells, abuse liability, biomarkers, inhalation toxicology, biostatistics, and more - Updated with the latest international guidelines for nonclinical toxicology in both small and large molecules - Incorporates practical examples in order to illustrate day-to-day activities and the expectations associated with working in nonclinical toxicology
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fusion Energy Update written by and published by . This book was released on 1978 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Plasma Scattering of Electromagnetic Radiation written by John Sheffield and published by Academic Press. This book was released on 2010-11-25 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents one of the most powerful methods of plasma diagnosis in exquisite detail, to guide researchers in the theory and measurement techniques of light scattering in plasmas. Light scattering in plasmas is essential in the research and development of fusion energy, environmental solutions, and electronics.Referred to as the "Bible" by researchers, the work encompasses fusion and industrial applications essential in plasma research. It is the only comprehensive resource specific to the plasma scattering technique. It provides a wide-range of experimental examples and discussion of their principles with worked examples to assist researchers in applying the theory. - Computing techniques for solving basic equations helps researchers compare data to the actual experiment - New material on advances on the experimental side, such as the application of high density plasmas of inertial fusion - Worked out examples of the scattering technique for easier comprehension of theory
