Download or read book Phytochemical and Pharmacological Evaluation of Catharanthus Roseus written by Mohammad Asadujjaman and published by LAP Lambert Academic Publishing. This book was released on 2011-07 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Catharanthus roseus (Madagascar Periwinkle) is a species of Catharanthus native and endemic to Madagascar. Synonyms include Vinca rosea (the basionym), Ammocallis rosea, and Lochnera rosea; other English names occasionally used include Cape Periwinkle, Rose Periwinkle, Rosy Periwinkle, and "Old-maid."In an in vitro analysis, Catharanthus was the most potent antioxidant herb analyzed among many others, including Thymus, Salvia and Rosmarinus.Catharanthus roseus L (C. roseus) has been used to treat a wide assortment of diseases including diabetes.The leaves of Catharanthus roseus constitute the only source of the well known indolomonoterpenic alkaloids vincristine and vinblastine.Increased wound contraction and tensile strength, augmented hydroxyproline content along with antimicrobial activity support the use of C. roseus in the topical management of wound healing.

Download or read book Phytochemical and Pharmacological Evaluation of Twelve Plant Accessions written by Sit Mui Agnes Tang and published by . This book was released on 1971 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Catharanthus roseus written by M. Naeem and published by Springer. This book was released on 2017-04-11 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book studies the production of indole alkaloids in the important medicinal plant Catharanthus roseus (L.) G. Don, commonly known as periwinkle. The anticancer alkaloids, viz. vinblastine and vincristine, are mainly present in the leaves of C. roseus and inhibit the growth of cancer cells by hindering the formation of mitotic apparatus during cell division. Further, vinblastine helps increase the chance of surviving childhood leukemia while vincristine is used to treat Hodgkin’s disease. Great efforts have been made to produce these alkaloids at a large scale by the culture of plant cells. In view of this worldwide demand for commercial use, this book explores how to maximize the production of anticancer alkaloids from C. roseus. This reference book will be helpful for research students, teachers, ethnobotanists, pharmacologists and herbal growers who have a strong interest in this anticancer medicinal plant of paramount importance.

Download or read book Botanical Leads for Drug Discovery written by Bikarma Singh and published by Springer Nature. This book was released on 2020-10-05 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Active botanical ingredients are a prime requirement for herbal formulations and discovering a drug is all about integration of science disciplines. In recent decades there has been a growing interest in treating wounds and diseases using traditional remedies based on local herbs, combined with chemical advances. Although this has led to the development of new bioactive ingredients from plants, there has been little success in terms of clinical trials and post-marketing studies to comply with FDA guidelines. Plants have been used as a source of medicine throughout history and continue to serve as the basis for many pharmaceuticals used today. However, despite the modern pharmaceutical industry being founded on botanical medicine, synthetic approaches to drug discovery have now become standard. Science-driven translational discovery and botanical development has created a new reality, leading to enormous changes in strategies, technologies and the disciplines involved, which have been embraced by the pharmaceutical and biotech industries. This book gathers scientific expertise and traditional knowledge to promote the discovery and development of new formulations and drugs based on active ingredients and to provide guidance on taking these to clinical trials. It discusses major topics, such as how the phytochemical composition of many plants has changed over time due to factors like cultivation, which can have both positive and negative effects on the levels of bioactive compounds. It also explores the importance of plants as a valuable source of therapeutic compounds as a result of their vast biosynthetic capacity, and classifies them according to their intended use, safety and regulatory status. Further, the book offers insights into the regulatory aspects of botanical products, which is an important issue when considering standardization and quality assessment, and also examines the commercial aspects of plant-derived medications and their proven role in the treatment of chronic diseases such as heart disease, high blood pressure, pain, asthma, and other associated conditions. Given its scope, this book is a valuable tool for botanists, natural product chemists, pharmacologists and microbiologists involved in the study of phytochemicals for drug discovery.

Download or read book Alkaloids written by Joanna Kurek and published by BoD – Books on Demand. This book was released on 2019-11-13 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Alkaloids" is intended for by chemistry, biochemistry, pharmacy, and other medical students, biologists, chemists, biochemists, and other professionals involved in the field of alkaloids. All chapters in this book are written by professionals in the areas of alkaloid chemistry, biology, pharmacy, and other interesting applications. The chapters cover interesting and less obvious information about different groups of alkaloids.

Download or read book Handbook of 200 Medicinal Plants written by Shahid Akbar and published by Springer Nature. This book was released on 2020-04-21 with total page 2076 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to provide pharmacologists and researchers of natural products a comprehensive review of 200 medicinal plants, their vernacular names in various languages and their medicinal uses around the world, and in some cases, a historical perspective. Chemical constituents of each plant with the putative active constituent, and available up to date pharmacological studies (until 2017 on PubMed) with each medical activity explored and its relationship with traditional uses, are described for each plant. Any variations in chemical constituents and their effects on pharmacological studies outcome have been highlighted. All clinical trials conducted, with sufficient details, have been included. Nationalities and racial identities of participants of clinical trials are identified to impress upon the social, cultural and dietary influences on the clinical outcomes. Toxicity studies and potential interactions with prescribed drugs, and full spectrum of references are included.

Download or read book Phytochemistry of Medicinal Plants written by John T. Arnason and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemicals from medicinal plants are receiving ever greater attention in the scientific literature, in medicine, and in the world economy in general. For example, the global value of plant-derived pharmaceuticals will reach $500 billion in the year 2000 in the OECD countries. In the developing countries, over-the-counter remedies and "ethical phytomedicines," which are standardized toxicologically and clinically defined crude drugs, are seen as a promising low cost alternatives in primary health care. The field also has benefited greatly in recent years from the interaction of the study of traditional ethnobotanical knowledge and the application of modem phytochemical analysis and biological activity studies to medicinal plants. The papers on this topic assembled in the present volume were presented at the annual meeting of the Phytochemical Society of North America, held in Mexico City, August 15-19, 1994. This meeting location was chosen at the time of entry of Mexico into the North American Free Trade Agreement as another way to celebrate the closer ties between Mexico, the United States, and Canada. The meeting site was the historic Calinda Geneve Hotel in Mexico City, a most appropriate site to host a group of phytochemists, since it was the address of Russel Marker. Marker lived at the hotel, and his famous papers on steroidal saponins from Dioscorea composita, which launched the birth control pill, bear the address of the hotel.

Download or read book In Vitro Embryogenesis in Plants written by Trevor A. Thorpe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: In vitro Embryogenesis in Plants is the first book devoted exclusively to this topic. As the ultimate demonstration of totipotency in plants, somatic and haploid embryogenesis is of vital importance to all those working on or interested in basic and applied aspects of plantlet information and regeneration. The text includes comprehensive reviews written by experts, on all facts of in vitro and in vivo embryogenesis. Some chapters deal with the morphogenic, structural and developmental, physiological and biochemical, and molecular biological aspects of the subject. Chapters are also devoted to haploid embryogenesis, asexual embryogenesis in nature, zygotic embryogenesis, and zygotic embryo culture. Detailed tables summarizing successful somatic embryogenesis in all vascular plants are also included. This book, therefore, brings together previously scattered information to provide an indispensable reference book for both active researchers, graduate students and anyone interested in this aspect of tissue culture technology and plant development.

Download or read book Novel Plant Bioresources written by Ameenah Gurib-Fakim and published by John Wiley & Sons. This book was released on 2014-04-03 with total page 1141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel Plant Bioresources: Applications in Food, Medicine and Cosmetics serves as the definitive source of information on under-utilized plant species, and fills a key niche in our understanding of the relationship of human beings with under-utilized plants. By covering applications in food, medicine and cosmetics, the book has a broad appeal. In a climate of growing awareness about the perils of biodiversity loss, the world is witnessing an unprecedented interest in novel plants, which are increasingly prized for their potential use in aromas, dyes, foods, medicines and cosmetics. This book highlights these plants and their uses. After an introductory section which sets the scene with an overview of the historical and legislative importance of under-utilized plants, the main four parts of the book are dedicated to the diverse potential application of novel plant bioresources in Food, Medicine, Ethnoveterinary Medicine and Cosmetics. Examples and contributors are drawn from Africa, Europe, the USA and Asia. The economic, social, and cultural aspects of under-utilized plant species are addressed, and the book provides a much needed boost to the on-going effort to focus attention on under-utilized plant species and conservation initiatives. By focusing on novel plants and the agenda for sustainable utilization, Novel Plant Bioresources highlights key issues relevant to under-utilized plant genetic resources, and brings together international scholars on this important topic.

Download or read book Biotechnology of Hairy Root Systems written by Pauline M Doran and published by Springer. This book was released on 2013-10-04 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: Victor P. Bulgakov, Yuri N. Shkryl, Galina N. Veremeichik, Tatiana Y. Gorpenchenko and Yuliya V. Vereshchagina: Recent Advances in the Understanding of Agrobacterium rhizogenes-Derived Genes and Their Effects on Stress Resistance and Plant Metabolism. Le Zhao, Guy W. Sander and Jacqueline V. Shanks: Perspectives of the Metabolic Engineering of Terpenoid Indole Alkaloids in Catharanthus roseus Hairy Roots. Jian Wen Wang and Jian Yong Wu: Effective Elicitors and Process Strategies for Enhancement of Secondary Metabolite Production in Hairy Root Cultures. Amanda R. Stiles and Chun-Zhao Liu: Hairy Root Culture: Bioreactor Design and Process Intensification. Marina Skarjinskaia, Karen Ruby, Adriana Araujo, Karina Taylor, Vengadesan Gopalasamy-Raju, Konstantin Musiychuk, Jessica A. Chichester, Gene A. Palmer, Patricia de la Rosa, Vadim Mett, Natalia Ugulava, Stephen J. Streatfield and Vidadi Yusibov: Hairy Roots as a Vaccine Production and Delivery System. Zahwa Al-Shalabi and Pauline M. Doran: Metal Uptake and Nanoparticle Synthesis in Hairy Root Cultures.

Download or read book Herbs Shrubs and Trees of Potential Medicinal Benefits written by Azamal Husen and published by CRC Press. This book was released on 2022-06-20 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been a worldwide increase in the demand for medicinal plants that aid the immune system, and considerable progress has been made in plant-based drug development. Herbs, Shrubs and Trees of Potential Medicinal Benefits examines how plants are used in the development of drugs preventing and treating cancer, hepatitis, asthma, influenza, HIV, and other diseases by manipulating a variety of bioactive molecules found in these plant parts. The book analyses how plants may strengthen human immunity, improve mood and brain function, enhance blood and oxygen circulation, boost the healing processes, and maintain blood pressure. Though many herbs, shrubs and trees have been identified for developing healthcare products, many of them require further exploration for potential usage. This volume in the Exploring Medicinal Plants series, presents information on herbs, shrubs and trees discussing traditional knowledge, chemical derivatives, and potential benefits of these items. Features: Identifies and highlights some medicinal herbs, shrubs and or trees around the world, presenting overall potential benefits to human health. Explores important medicinal plants for their bioactive constituents and phytochemicals. Discusses medicinal herbs, shrubs, and or trees for their uses in herbal drug preparation. Written by an international panel of plant scientists, this book is an essential resource to students, pharmacists, and chemists. It provides valuable information on fundamental chemical principles, modes of action, and product formulation of bioactive natural products derived from plants for medical applications.

Download or read book Therapeutic Use of Medicinal Plants and their Extracts Volume 2 written by A.N.M. Alamgir and published by Springer. This book was released on 2019-02-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book starts with a general introduction to phytochemistry, followed by chapters on plant constituents, their origins and chemistry, but also discussing animal-, microorganism- and mineral-based drugs. Further chapters cover vitamins, food additives and excipients as well as xenobiotics and poisons. The book also explores the herbal approach to disease management and molecular pharmacognosy and introduces methods of qualitative and quantitative analysis of plant constituents. Phytochemicals are classified as primary (e.g. carbohydrates, lipids, amino acid derivations, etc.) or secondary (e.g. alkaloids, terpenes and terpenoids, phenolic compounds, glycosides, etc.) metabolites according to their metabolic route of origin, chemical structure and function. A wide variety of primary and secondary phytochemicals are present in medicinal plants, some of which are active phytomedicines and some of which are pharmaceutical excipients.

Download or read book The Catharanthus Genome written by Chittaranjan Kole and published by Springer Nature. This book was released on 2022-01-24 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first comprehensive compilation of deliberations on botany, medicinal importance, genetic diversity, classical genetics and breeding, in vitro biosynthesis, somatic embryogenesis, genetic transformation, molecular mapping, genome sequence, and functional genomics of Catharanthus roseus. Catharanthus is the most important medicinal plant in the world that contains about 130 therapeutic alkaloids out of which vinblastine and vincristine are the two highly used anticancer drugs sold by the pharmaceutically industries. Altogether, the book contains about 10 chapters authored by globally reputed experts on the relevant field of this plant. This book is useful to the students, teachers and scientists in the academia and relevant private companies interested in horticulture, genetics, breeding, pathology, entomology, physiology, molecular genetics and breeding, in vitro culture and genetic engineering, and structural and functional genomics. This book is also useful to pharmaceutical industries.

Download or read book Medical Botany written by Walter H. Lewis and published by Wiley. This book was released on 1982-02-11 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants as Medicine.... A Natural Approach to Self-Health Medical Botany: Plants Affecting Man?s Health, Walter H. Lewis, Memory P.F. Elvin-Lewis Medical Botany is a fascinating look at the facts and fictions surrounding plants and man?not only which plants affect our bodies, but how they affect them. Authoritative, rich in anecdote and lore, lavishly illustrated, this encyclopedic reference brings within your reach the curative, healing, poisonous, allergenic, and psychoactive properties of thousands of plants. Its ready reference format allows you to turn instantly to information about a specific plant?s properties, its history, its use in orthodox medicine (where applicable) and its use in folk medicine. Discover a wealth of information on plants that have been used for such purposes as to treat peptic ulcers, to assist in the fight against cancer (in combination with chemotherapy), to help alleviate gout and diabetes, and to promote the healing of wounds. Each section begins with historical background of the plants discussed, with colorful stories ranging from Socrates? fatal hemlock to Timothy Leary?s experiments. There are informative discussions of how your body works, with sections covering heart and circulation, metabolism, nervous system, urogenital system, gastrointestinal tract, allergies, ear, internal poisons, and more. This intriguing compendium/reference will enlighten, entertain, and give you a healthier knowledge of plants. Praise for Medical Botany... "Skillfully organized, neatly written, highly informative, and well illustrated, this is a stimulating and useful reference volume. It is not a mere catalog of medicinal plants but a carefully prepared review of injurious, healing and nourishing, and psychoactive plants...should be a lasting joy for reference and a source of continued satisfaction..." ?American Scientist "I would recommend this text highly...useful for the layman who wishes an introduction to the topic. The authors have provided a fresh look at a classic subject and should be commended for their efforts." ?Economic Botany "...a vast compendium of information on medically important plants, both harmful and useful...commendable." ?New England Journal of Medicine

Download or read book Biological Activities of Alkaloids written by Sabino Aurelio Bufo and published by MDPI. This book was released on 2020-05-13 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products are increasingly attracting attention from both basic and applied science. Plant secondary metabolites, especially alkaloids, are receiving interest from a wide range of researchers due to their biological activity. They are produced to protect plants from diseases and herbivores. Therefore, they reveal a toxic activity that affects organisms at various levels of biological organization. A growing amount of research is proving their antimicrobial, antifungal, insecticidal, and anticancer activities. That makes them applicable in various fields from medicine, to pharmacology, veterinary, and toxicology, to crop protection. This Special Issue of Toxins, “Biological Activities of Alkaloids: From Toxicology to Pharmacology", collects 15 manuscripts describing the ecological, biological, pharmacological, and toxicological effects as well as structural and analytical aspects of plant alkaloids, their mode of action, and possible application in veterinary, medicine, and plant protection. These studies prove the potential for alkaloid application in various areas of science.

Download or read book Network Pharmacology written by Shao Li and published by Springer Nature. This book was released on 2021-09-29 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.

Download or read book Natural Products written by Kishan Gopal Ramawat and published by Springer. This book was released on 2013-06-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work provides a wealth of information regarding medicinal plants and phytochemicals. It is addressed both to researchers and teachers. The handbook describes phytochemicals, which, by the strictest definition, are chemicals that are produced by plants. During the last decades, more and more groups became actively involved in exploring plants for useful metabolites that lead to the identification of several useful curative agents and many promising molecules to fight and/or prevent diseases, including carcinogenesis and stroke. But when we talk about phytochemicals, there are also medicinal plants where not a single molecule is responsible for the observed properties. This reference work therefore reviews and compiles the information on both these aspects. The volumes contain contributions on phytochemicals and herbal extracts. A large number of natural products obtained from plants and microorganisms is used in cosmetic, drug, flavor and fragrance industries. For this compilation, a range of the most important medicinal herbs and phytochemicals were selected and are described by the recognized authors in the field. The present reference work encompasses the information about well established phytochemicals, biology and biotechnology of medicinal plants or their products, their biosynthesis, novel production strategies, demand and uses, metabolism and bioavailability. There is a surge of information published in recent years on herbal medicine and their pharmacologic effects with single books available on varied subjects. However, all this information is widespread and difficult to overview. Researchers who wish to keep a pace with the rapidly developing field of natural products can now consult this newly compiled handbook to find all information about bioactive molecules and medicinal plants thoroughly compiled in one place!