Download or read book Physiology Past Present and Future written by D. J. Anderson and published by Elsevier. This book was released on 2013-10-22 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiology: Past, Present and Future documents the proceedings of a symposium in honor of Yngve Zotterman held in the Department of Physiology, Medical School, University of Bristol on 11-12 July 1979. The idea for the symposium was spurred by the knowledge that Yngve would reach the age of 80 in September 1978 and the belief that he would welcome a meeting to celebrate his great age and achievement, in the company of some of his distinguished friends and collaborators. The symposium discussed advances in several branches of physiology. These include studies on C-fiber afferents in the viscera, skin, and deeper somatic tissues; touch and pain; tactile paths in the nervous systems of mammals; jaw reflexes evoked from the cerebral cortex; thermoreception; and temperature sensitivity of humans and monkeys. Also included are papers on taste cell transduction; how the sense of taste controls appetitive and instrumental behavior; and structural changes in the excitable membrane during excitation. The book concludes with a discussion on future trends, which begins with some challenging remarks by Yngve Zotterman. These remarks are then taken up and developed by the speakers.

Download or read book Physiology Past Present and Future written by Declan John Anderson and published by . This book was released on 1980 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Past Present and Future of Integrated History and Philosophy of Science written by Emily Herring and published by Routledge. This book was released on 2019-05-14 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrated History and Philosophy of Science (iHPS) is commonly understood as the study of science from a combined historical and philosophical perspective. Yet, since its gradual formation as a research field, the question of how to suitably integrate both perspectives remains open. This volume presents cutting edge research from junior iHPS scholars, and in doing so provides a snapshot of current developments within the field, explores the connection between iHPS and other academic disciplines, and demonstrates some of the topics that are attracting the attention of scholars who will help define the future of iHPS.

Download or read book Exercise Physiology written by Charles M Tipton and published by Springer. This book was released on 2013-05-27 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: This history of exercise physiology is written from a systems perspective. It examines the responses of key physiological systems to the conditions of acute and chronic exercise, as well as their coupling with integrative responses.

Download or read book Folds of Past Present and Future written by Sarah Van Ruyskensvelde and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-09-07 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together important theoretical and methodological issues currently being debated in the field of history of education. The contributions shed insightful and critical light on the historiography of education, on issues of de-/colonization, on the historical development of the educational sciences and on the potentiality attached to the use of new and challenging source material.

Download or read book Higher and Colder written by Vanessa Heggie and published by University of Chicago Press. This book was released on 2019-08-02 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the long twentieth century, explorers went in unprecedented numbers to the hottest, coldest, and highest points on the globe. Taking us from the Himalaya to Antarctica and beyond, Higher and Colder presents the first history of extreme physiology, the study of the human body at its physical limits. Each chapter explores a seminal question in the history of science, while also showing how the apparently exotic locations and experiments contributed to broader political and social shifts in twentieth-century scientific thinking. Unlike most books on modern biomedicine, Higher and Colder focuses on fieldwork, expeditions, and exploration, and in doing so provides a welcome alternative to laboratory-dominated accounts of the history of modern life sciences. Though centered on male-dominated practices—science and exploration—it recovers the stories of women’s contributions that were sometimes accidentally, and sometimes deliberately, erased. Engaging and provocative, this book is a history of the scientists and physiologists who face challenges that are physically demanding, frequently dangerous, and sometimes fatal, in the interest of advancing modern science and pushing the boundaries of human ability.

Download or read book The Present Tendencies and the Future Compass of Physiological Science written by Archibald Vivian Hill and published by . This book was released on 1923 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Future of Physiology 2020 and Beyond written by George E. Billman and published by Frontiers Media SA. This book was released on 2021-07-30 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic eBook includes articles from Volume I and II of The Future of Physiology: 2020 and Beyond series: Research Topic “The Future of Physiology: 2020 and Beyond, Volume I” Research Topic “The Future of Physiology: 2020 and Beyond, Volume II” The term Physiology was introduced in the 16th century by Jean Francois Fernel to describe the study of the normal function of the body as opposed to pathology, the study of disease. Over the ensuing centuries, the concept of physiology has evolved and a central tenet that unites all the various sub-disciplines of physiology has emerged: the quest to understand how the various components of an organism from the sub-cellular and cellular domain to tissue and organ levels work together to maintain a steady state in the face of constantly changing and often hostile environmental conditions. It is only by understanding normal bodily function that the disruptions that leads to disease can be identified and corrected to restore the healthy state. During the summer of 2009, I was invited by Dr. Henry Markram, one of the founders of the “Frontiers In” series of academic journals, to serve as the Field Chief Editor and to launch a new Open-access physiology journal that would provide a forum for the free exchange of ideas and would also meet the challenge of integrating function from molecules to the intact organism. In considering the position, I needed to answer two questions: 1) What exactly is Open-access publishing?; and 2) What could Frontiers in Physiology add to the already crowded group of physiology related journals? As a reminder, the traditional model of academic publishing “is a process by which academic scholars provide material, reviewing, and editing expertise for publication, free of charge, then pay to publish their work” and, to add insult to injury, they and their colleagues must pay the publisher a fee (either directly or via an institutional subscription) to read their published work [slightly modified from the “The Devil’s Dictionary of Publishing” Physiology News (the quarterly newsletter of the Physiological Society) Spring 2019: Issue 114, page 8]. In the traditional model, the publisher, not the authors, owns the copyright such that the author must seek permission and may even be required to pay a fee to re-use their own material (such as figures) in other scholarly articles (reviews, book chapters, etc.). In contrast, individuals are never charged a fee to read articles published in open-access journals. Thus, scholars and interested laymen can freely access research results (that their tax dollars paid for!) even if their home institution does not have the resources to pay the often exorbitant subscription fees. Frontiers takes the open-access model one step further by allowing authors (rather than the publisher) to retain ownership (i.e., the copyright) of their intellectual property. Having satisfied the first question, I then considered whether a new physiology journal was necessary. At that point in time there were no open-access physiology journals, and further, many aspects of physiology were not covered in the existing journals. Frontiers afforded the unique opportunity to provide a home for more specialized sections under the general field journal, Frontiers in Physiology, with each section having an independent editor and editorial board. I therefore agreed to assume the duties of Field Chief Editor in November 2009. Frontiers in Physiology was launched in early 2010 and the first articles were published in April 2010. Since these initial publications, we have published over 10,000 articles and have become the most cited physiology journal. Clearly we must be fulfilling a critical need. Now that it has been over a decade since Frontiers in Physiology was launched, it is time to reflect upon what has been accomplished in the last decade and what questions and issues remain to be addressed. Therefore, it is the goal of this book to evaluate the progress made during the past decade and to look forward to the next. In particular, the major issues and expected developments in many of the physiology sub-disciplines will be explored in order to inspire and to inform readers and researchers in the field of physiology for the year 2020 and beyond. A brief summary of each chapter follows: In chapter 1, Billman provides a historical overview of the evolution of the concept of homeostasis. Homeostasis has become the central unifying concept of physiology and is defined as a self-regulating process by which a living organism can maintain internal stability while adjusting to changing external conditions. He emphasizes that homeostasis is not static and unvarying but, rather, it is a dynamic process that can change internal conditions as required to survive external challenges and can be said to be the very basis of life. He further discusses how the concept of homeostasis has important implications with regards to how best to understand physiology in intact organisms: the need for more holistic approaches to integrate and to translate this deluge of information obtained in vitro into a coherent understanding of function in vivo. In chapter 2, Aldana and Robeva explore the emerging concept of the holobiont: the idea that every individual is a complex ecosystem consisting of the host organism and its microbiota. They stress the need for multidisciplinary approaches both to investigate the symbiotic interactions between microbes and multicellular organisms and to understand how disruptions in this relationship contributes to disease. This concept is amplified in chapter 3 in which Pandol addresses the future of gastrointestinal physiology ,emphasizing advances that have been made by understanding the role that the gut microbiome plays in both health and in disease. Professor Head, in chapter 4, describes areas in the field of integrative physiology that remain to be examined, as well as the potential for genetic techniques to reveal physiological processes. The significant challenges of developmental physiology are enumerated by Burggren in chapter 5. In particular, he analyzes the effects of climate change (environmentally induced epigenetic modification) on phenotype expression. In chapter 6, Ivell and Annad-Ivell highlight the major differences between the reproductive system and other organ systems. They conclude that the current focus on molecular detail is impeding our understanding of the processes responsible for the function of the reproductive organs, echoing and amplifying the concepts raised in chapter 1. In chapter 7, Costa describes the role of both circadian and non-circadian biological “clocks” in health and disease, thereby providing additional examples of integrated physiological regulation. Coronel, in chapter 8, provides a brief history of the development of cardiac electrophysiology and then describes areas that require further investigation and includes tables that list specific questions that remain to be answered. In a similar manner, Reiser and Janssen (chapter 9) summarize some of the advancements made in striated muscle physiology during the last decade and then discuss likely trends for future research; to name a few examples, the contribution of gender differences in striated muscle function, the mechanisms responsible of age-related declines in muscle mass, and role of exosome-released extracellular vesicles in pathophysiology. Meininger and Hill describe the recent advances in vascular physiology (chapter 10) and highlight approaches that should facilitate our understanding of the vascular processes that maintain health (our old friend homeostasis) and how disruptions in these regulatory mechanisms lead to disease. They also stress the need for investigators to exercise ethical vigilance when they select journals to publish in and meetings to attend. They note that the proliferation of profit driven journals of dubious quality threatens the integrity of not only physiology but science in general. The pathophysiological consequences of diabetes mellitus are discussed in chapters 11 and 12. In chapter 11, Ecelbarger addresses the problem of diabetic nephropathy and indicates several areas that require additional research. In chapter 12, Sharma evaluates the role of oxidative damage in diabetic retinopathy, and then proposes that the interleukin-6-transsignaling pathway is a promising therapeutic target for the prevention of blindness in diabetic pateints. Bernardi, in chapter 13, after briefly reviewing the considerable progress that has been achieved in understanding mitochondrial function, lists the many questions that remain to be answered. In particular, he notes several areas for future investigation including (but not limited to) a more complete understanding of inner membrane permeability changes, the physiology of various cation channels, and the role of mitochondrial DNA in disease. In chapter 14, using Douglas Adam’s “The Hitchhikers Guide to the Universe” as a model, Bogdanova and Kaestner address the question why a young person should study red blood cell physiology and provide advice for early career scientists as they establish independent laboratories. They the, describe a few areas that merit further attention, not only related to red blood cell function, but also to understanding the basis for blood related disease, and the ways to increase blood supplies that are not dependent on blood donors. Finally, the last two chapters specifically focus on non-mammalian physiology. In chapter 15, Scanes asks the question, are birds simply feathered mammals, and then reviews several of the significant differences between birds and mammals, placing particular emphasis on differences in gastrointestinal, immune, and female reproductive systems. In the final chapter (chapter 16) Anton and co-workers stress that since some 95% of living animals species are invertebrates, invertebrate physiology can provide insights into the basic principles of animal physiology as well as how bodily function adapts to environmental changes. The future of Physiology is bright; there are many important and interesting unanswered questions that will require further investigation. All that is lacking is sufficient funding and a cadre of young scientists trained to integrate function from molecules to the intact organism. George E. Billman, Ph.D, FAHA, FHRS, FTPS Department of Physiology and Cell Biology The Ohio State University Columbus OH, United States

Download or read book Regeneration from cells to limbs Past present and future written by Jennifer R Morgan and published by Frontiers Media SA. This book was released on 2023-07-03 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Past present future of the Yale University School of Medicine and affiliated clinical institutes written by and published by . This book was released on 1922 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Cnidaria Past Present and Future written by Stefano Goffredo and published by Springer. This book was released on 2016-09-07 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a broad panorama of the current status of research of invertebrate animals considered belonging to the phylum Cnidaria, such as hydra, jellyfish, sea anemone, and coral. In this book the Cnidarians are traced from the Earth’s primordial oceans, to their response to the warming and acidifying oceans. Due to the role of corals in the carbon and calcium cycles, various aspects of cnidarian calcification are discussed. The relation of the Cnidaria with Mankind is approached, in accordance with the Editors’ philosophy of bridging the artificial schism between science, arts and Humanities. Cnidarians' encounters with humans result in a broad spectrum of medical emergencies that are reviewed. The final section of the volume is devoted to the role of Hydra and Medusa in mythology and art.

Download or read book Medical Reform and the Past Present and Future of Homoeopathy in Great Britain Second Edition By a Physician Practising Homoeopathy written by MEDICAL REFORM. and published by . This book was released on 1856 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book History of Exercise Physiology written by Tipton, Charles M. and published by Human Kinetics. This book was released on 2014-03-19 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Well illustrated with figures and photos, this text brings together leading authorities in exercise physiology to help readers understand the research findings and meet the most prominent professionals in the field.

Download or read book Myelin Mediated Inhibition of Axonal Regeneration Past Present and Future written by Sari Hannila and published by Frontiers Media SA. This book was released on 2017-07-06 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pioneering studies conducted in the 1980’s laid the foundation for the hypothesis that axonal regeneration is limited by CNS myelin, and the identification of myelin-associated glycoprotein (MAG), Nogo, and oligodendrocyte myelin glycoprotein (OMgp) as inhibitors of neurite outgrowth firmly established myelin as a key factor in regenerative failure. Mechanistically, it has been shown that MAG, Nogo, and OMgp mediate inhibition by binding to either Nogo receptor (NgR) or paired immunoglobulin receptor B (PirB), and initiating a signaling cascade that culminates in the activation of RhoA. Since the discovery of these proteins, there has been tremendous interest in identifying compounds and molecular mechanisms that are capable of overcoming myelin-mediated inhibition. Many studies have focused on pharmacological antagonism of receptors and signaling intermediates, while others have sought to identify and enhance endogenous pro-regenerative pathways. The most notable example of the latter is the conditioning lesion effect, which led to the discovery of cyclic AMP’s ability to overcome inhibition by MAG and myelin. Many of the agents tested in these studies have been shown to promote axonal regeneration in vivo, and this research topic allows researchers to share information about new treatments that have been developed in both academia and industry. As we look toward the future, it is becoming increasingly clear that reversal of myelin-mediated inhibition alone will not be sufficient to produce functional recovery from spinal cord injury, and that other factors, such as astroglial scarring, the expression of chondroitin sulfate proteoglycans, neuronal cell death, and lack of neurotrophic support, must also be taken into consideration. Combinatorial approaches therefore hold a great deal of promise, and we hope to initiate a dialogue on how stem cell transplantation, chondroitinase ABC, gene therapy, growth-promoting agents, and other methods can be combined to optimize functional recovery. We introduce this topic in honor of the life and work of Dr. Marie T. Filbin (1955-2014). Through these articles, we highlight past achievements in the field, novel findings, unanswered questions and innovative ideas that we hope will lead to new advances in axonal regeneration.

Download or read book The Past Present and Future of England s Language written by William Marshall and published by . This book was released on 1878 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Physiology and Behavior Therapy written by James G. Hollandsworth Jr. and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the widespread use of psychophysiological concepts and meth ods in behavior therapy, there is no text devoted specifically to the subject. The publication of this book is necessary and timely, and should promote a better appreciation of the physiological roots of behavior therapy. The important connections between physiology and behavior thera py receive insufficient recognition nowadays, despite the fact that his torically one of the two main streams of behavior therapy grew out of a physiological basis. Wolpe's early work was closely connected to phys iology, and in contemporary behavior therapy, Lang's critical contribu tion is firmly based in psychophysiology. The physiological component is prominent in Lang's highly productive three-systems analysis of emo tion and in its application to psychological disorders. In addition, there are philosophical reasons for maintaining the close connection between behavior therapy and physiology. The existence of these connections, and their justification, can raise few objections, and it is therefore curious that a book on this significant subject has not appeared earlier. The importance of physiology for behavior therapy can be illus trated by considering the nature of a behavior therapy deprived of its physiological connections. It would survive, certainly, but as a rather scrawny, uninteresting orphan among many clamorous competitors.

Download or read book Past Present and Future of Chattanooga Tennessee the Industrial Center of the South written by and published by . This book was released on 1885 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: