Download or read book Photodynamic Inactivation of Microbial Pathogens written by Michael R Hamblin and published by Royal Society of Chemistry. This book was released on 2015-11-09 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photodynamic therapy (PDT) was discovered over one hundred years ago after observing the death of microorganisms upon exposure to dyes and light. It is the combination of non-toxic dyes and harmless visible light that, in the presence of oxygen, produce highly toxic reactive species. The principal medical application during the last century was in cancer therapy but, in these days of rising antibiotic resistance, PDT shows increasing promise as an alternative approach to treating infections. PDT has also been used in blood product sterilization, peridontology, acne reduction, and the treatment of viral lesions such as those caused by human papilloma virus. It may also have potential as an environmentally friendly pesticide. This is the first and only book to comprehensively cover the use of light and photosensitising agents for controlling microbial pathogens. It provides a comprehensive and up-to-date coverage of an emerging field. There are several chapters on the design of antimicrobial photosensitizers, their use to kill pathogenic organisms and their success in treating infections in animal models. It has long been known that gram-positive bacteria are highly susceptible to photoinactivation but the book also discusses means of widening the range of microorganisms that can be tackled by PDT. Edited by two pioneers in the application of PDT to medical and environmental issues, this book covers the basic science, translational research in animals, and the clinical applications in various medical specialities. It represents an indispensable resource for microbiologists and infectious disease doctors as well as dentists, dermatologists, gastroenterologists and transfusion specialists.
Download or read book Photodynamic Inactivation of Bacterial Pathogens written by Peter Walker and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Applications of Porphyrinoids as Functional Materials written by Heinrich Lang and published by Royal Society of Chemistry. This book was released on 2021-08-18 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an overview of the applications and potential applications of porphyrins and related macrocycles as smart or functional materials.
Download or read book Aspects of Photodynamic Inactivation of Bacteria written by Marina Nisnevitch and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing resistance of bacteria to antibiotics is a serious worldwide problem, and to combat resistant bacteria, new antibacterial approaches are to be developed. One alternative to traditional antibiotic therapy is photodynamic antimicrobial chemotherapy (PACT). PACT is based on excitation of photosensitizers (PS) capable of transferring the absorbed light energy to dissolved molecular oxygen causing generation of reactive oxygen species, which irreversibly damage bacterial cell components. The overall efficiency of PACT has been proven for Gram-positive and Gram-negative bacteria. The effectiveness of PACT can be increased by encapsulation of PS in liposomes providing more concentrated delivery of PS, enhanced cytotoxicity, improved pharmacokinetic properties, sustained release, and prolonged action of the PS. For continuous and reusable application, PS can be immobilized in polymers. Chemiluminescence, sonodynamic treatment, and radiofrequency irradiation allow to perform excitation of PS in the dark without external illumination, opening prospects for combating internal infections. Combination of PS with antibiotics can gain a synergistic effect, allowing in some cases to overcome the resistance of bacteria to antibiotics.
Download or read book Development of Novel Photosensitizers for Photodynamic Inactivation of Bacteria written by Elke Feese and published by . This book was released on 2011 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Science and Technology Against Microbial Pathogens written by A. Méndez-Vilas and published by World Scientific. This book was released on 2011 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial susceptibility profile and effect of stem bark extracts of Curtisia dentata on multi-drug resistant verotoxic Escherichia coli and Acinetobacter spp. isolates obtained from water and wastewater samples / Hamuel James Doughari [und weitere]. Antimicrobial utilization in intensive care units of a private tertiary care hospital / Pramil Tiwari, Vani Yadav and Shilpi Singh. Bacterial clearance from blood in mice infected by S. pneumoniae (penicillin MIC = 16 ug/ml) presenting specific IgG (non-protective levels) and treated with sub-therapeutic regimens of cefditoren (a highly bound cephalosporin) / Fabio Cafini [und weitere]. Characterisation of methicillin resistant Staphylococcus aureus isolates from hospitalised patients / Vladimir Kmet, Daniela Ohlasova and Milan Niks. Characterization of methicillin-resistant coagulase-negative Staphylococci isolates from blood cultures in a Brazilian University Hospital / Valeria Cataneli Pereira and Maria de Lourdes Ribeiro de Souza da Cunha. Control of bacterial contamination in boar semen doses / J.M. Morrell and Margareta Wallgren. Diffusion of extended-spectrum B-lactamase producing Enterobacter cloacae in a kidney transplantation unit / S. Hammami [und weitere]. Effect of antifungal agents on non-Candida albicans Candida species enzymatic activity / M. Negri [und weitere]. Effect of chitosan, nisin and storage time on the growth of Listeria innocua and Shewanella putrefaciens in fish homogenates / L.I. Schelegueda, M.F. Gliemmo and C.A. Campos. ESBL-producing Enterobacteriaceae in the northern Portugal - antimicrobial susceptibility and molecular epidemiology / R. Fernandes and C. Prudencio. Observations on the antimicrobial susceptibility of Staphylococcus pseudintermedius following the introduction of cefovecin for clinical use in Europe / Y. Chaudhry, A. Robinson and K.S. Godinho. Oxacillin resistance among Staphylococcus aureus isolated from peritoneal dialysis related peritonitis / C.H. Camargo [und weitere]. Resistance detection and susceptibility profile in Staphylococcus spp. isolated from patients with urinary tract infection (UTI) / Adriano Martison Ferreira [und weitere]. Resistance distribution profile of MBL, ESBL and multidrug resistant Gram negatives isolated at a tertiary care hospital in India / K.H. Bhutada and V.R. Shende
Download or read book Redox Active Therapeutics written by Ines Batinić-Haberle and published by Springer. This book was released on 2016-10-13 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer and the medical aspects of redox-active drugs, assuming little in the way of prior knowledge. Subsequent sections and chapters describe more specialized aspects of central nervous system injuries, neurodegenerative diseases, pain, radiation injury and radioprotection (such as of brain, lungs, head and neck and erectile function) and neglected diseases (e.g., leishmaniasis). It encompasses several major classes of redox-active experimental therapeutics, which include porphyrins, salens, nitrones, and most notably metal-containing (e.g., Mn, Fe, Cu, Zn, Sb) drugs as either single compounds or formulations with nanomaterials and quantum dots. Numerous illustrations, tables and figures enhance and complement the text; extensive references to relevant literature are also included. Redox-Active Therapeutics is an invaluable addition to Springer’s Oxidative Stress in Applied Basic Research and Clinical Practice series. It is essential reading for researchers, clinicians and graduate students interested in understanding and exploring the Redoxome—the organism redox network—as an emerging frontier in drug design, redox biology and medicine.
Download or read book Porphycenes in Photodynamic Therapy of Cancer Cells and Photodynamic Inactivation of Bacteria written by Natalia Masiera and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Photosensitizers written by and published by . This book was released on 2016-12-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Oral Biofilms written by S. Eick and published by Karger Medical and Scientific Publishers. This book was released on 2020-12-21 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms are highly organized polymicrobial communities that are embedded in an extracellular matrix and formed on natural and artificial surfaces. In the oral cavity, biofilms are formed not only on natural teeth, but also on restorative materials, prosthetic constructions, and dental implants. Oral diseases like caries, gingivitis, periodontitis, and also pulp inflammation are associated with biofilms. This publication is an up-to-date overview on oral biofilms from different clinically relevant perspectives. Experts comprising basic researchers and clinicians report on recent research relating to biofilms - from general summaries to recommendations for daily clinical work. This book covers all aspects of oral biofilms, including models used in the laboratory, biofilms in dental water unit lines, periodontal and peri-implant biofilms, caries-related biofilms, halitosis, endodontic biofilms, and Candida infections, as well as biofilms on dental materials and on orthodontic appliances. Several chapters deal with anti-biofilm therapy, from the efficacy of mechanical methods and the use of antimicrobials, to alternative concepts. This publication is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on biofilms.
Download or read book The Science of Phototherapy An Introduction written by Leonard I. Grossweiner and published by Springer Science & Business Media. This book was released on 2005-01-27 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume emphasizes the science underlying the various phototherapy procedures, which encompasses aspects of classical and molecular photophysics, biological photochemistry, photobiology and biophotonics. Suitable as an introductory reference or textbook.
Download or read book Multiple Action Based Design Approaches to Antibacterials written by John Bremner and published by Springer Nature. This book was released on 2021-04-05 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers intentional design aspects for combinations of drugs, single-molecule hybrids with potential or actual multiple actions, pro-drugs which could yield multiple activity outcomes, and future possibilities. The approach of the book is interdisciplinary, and it provides greater understanding of the complex interplay of factors involved in the medicinal chemistry design and laboratory development of multiply active antibacterials. The scope of the book appeals to readers who are researching in the field of antibacterials using the approach of medicinal chemistry design and drug development.
Download or read book Photodynamic Inactivation written by Hi-mui Tang and published by . This book was released on 2009 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Endodontic Microbiology written by Ashraf F. Fouad and published by John Wiley & Sons. This book was released on 2017-02-06 with total page 878 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endodontic Microbiology, Second Edition presents a comprehensive reference to the microbiology, pathogenesis, management, and healing of endodontic pathosis, emphasizing the importance of biological sciences in understanding and managing endodontic disease and its interaction with systemic health. Provides a major revision to the first book to focus on the problems related to microbes in the root canal and periapical tissues Updates current knowledge in endodontic pathosis, especially regarding next generation sequencing and microbial virulence Presents useful diagrams, images, radiographs, and annotated histological images to illustrate the concepts Emphasizes the importance of biological science in understanding and managing endodontic disease Includes contributions from the leading researchers and educators in the field
Download or read book Photodynamic Medicine written by Herwig Kostron and published by Royal Society of Chemistry. This book was released on 2016 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Series in Photochemical and Photobiological Sciences. Photodynamic therapy (PDT) is increasingly being used amongst health practitioners in combating a variety of disease. This book reviews the current state of development of PDT, and also presents the foreseeable advancements of the field in the next decade. Practitioners in biological sciences, biotechnology and medicinal and pharmaceutical chemistry will find this book an invaluable source of information. Chapters are drawn from research discusses at the 10th International Symposium on Photodynamic Therapy and Photodiagnosis in Clinical Practice in Brixen and are written and edited by leaders in the field. Mirroring the philosophy of that meeting, this book contains an informative balance of the basic sciences and clinical applications of PDT. Following an introduction to PDT, its history, and how techniques have developed, chapter serve as a practical guide for practitioners, covering topics such as sensitizer dosage and light dosage, and examples of relevant studies. The text goes further tp explore areas outside the medical field, such as the impact of PDT on society and the environment, and the economics of therapies. This book is dedicated to the memory of Professor Giulio Jori, and expert in this field, who sadly passed away on the 23rd December 2014.
Download or read book Therapeutic Ultrasound written by Jean-Michel Escoffre and published by Springer. This book was released on 2015-10-20 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights advances and prospects of a highly versatile and dynamic research field: Therapeutic ultrasound. Leading experts in the field describe a wide range of topics related to the development of therapeutic ultrasound (i.e., high intensity focused ultrasound, microbubble-assisted ultrasound drug delivery, low intensity pulsed ultrasound, ultrasound-sensitive nanocarriers), ranging from the biophysical concepts (i.e., tissue ablation, drug and gene delivery, neuromodulation) to therapeutic applications (i.e., chemotherapy, sonodynamic therapy, sonothrombolysis, immunotherapy, lithotripsy, vaccination). This book is an indispensable source of information for students, researchers and clinicians dealing with non-invasive image-guided ultrasound-based therapeutic interventions in the fields of oncology, neurology, cardiology and nephrology.
Download or read book Bioinorganic Photochemistry written by Grazyna Stochel and published by John Wiley & Sons. This book was released on 2009-06-10 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinorganic photochemistry is a rapidly evolving field integrating inorganic photochemistry with biological, medical and environmental sciences. The interactions of light with inorganic species in natural systems, and the applications in artificial systems of medical or environmental importance, form the basis of this challenging inter-disciplinary research area. Bioinorganic Photochemistry provides a comprehensive overview of the concepts and reactions fundamental to the field, illustrating important applications in biological, medical and environmental sciences. Topics covered include: Cosmic and environmental photochemistry Photochemistry of biologically relevant nanoassemblies Molecular aspects of photosynthesis Photoinduced electron transfer in biosystems Modern therapeutic strategies in photomedicine The book concludes with an outlook for the future of environmental protection, discussing emerging techniques in the field of pollution abatement, and the potential for bioinorganic photochemistry as a pathway to developing cheap, environmentally friendly sources of energy. Written as an authoritative guide for researchers involved in the development of bioinorganic photochemical processes, Bioinorganic Photochemistry is also accessible to scientists new to the field, and will be a key reference source for advanced courses in inorganic, and bioinorganic chemistry.
