Download or read book Skin Pharmacology and Toxicology written by Corrado L. Galli and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major skin diseases, including acne, psoriasis and eczcma, affect the majority of the population at some time in their lives. In general, these diseases are physically and psychologically disfiguring for the sufferers; furthermore, by their very chronic nature skin diseases, unlike most other disease processes, present both acute and chronic therapy problems. In addition, the chronic nature of these diseases can present certain economic problems. Firstly, chronic therapy is becoming increasingly expensive and secondly, patients adhering to a strict treatment regimen will frequently be absent from their gainful employment for either medical consultation or treatment. Given that in all NATO countries the average age of the population is continually increasing, these chronic skin diseases will increase in importance in the coming years. Furthermore, as the average population age increases, additional disease processes such as skin photodamage and carcinogenicity risk becoming major areas of therapeutic concern. This book reviews in detail the major scientific areas of interest for research and clinical scientists working in skin pharmacology and toxicology. The basic principles relating to an understanding of how drugs and chemicals may influence either the skin or the body as a whole are discussed in detail by recognized international scientific experts.
Download or read book Pharmacology of the Skin written by Hasan Mukhtar and published by Springer. This book was released on 1991-12-07 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a balanced, state-of-the-art summary of pharmacology as it relates to the skin. Topics discussed include structure of the skin and its barrier function; model systems for research in skin pharmacology; the drug metabolizing capability of the skin, skin pharmacology in health and disease; the role of oxidants and antioxidants in the skin; immunopharmacology of the skin; signal transduction, protein kinase C and the role of the eicosanoid receptors in skin; and cutaneous chemical- and photo-carcinogenesis. Pharmacology of the Skin provides essential information for investigators working in cutaneous biology, investigative and clinical dermatologists, pharmacologists, pharmacists, biochemists, and workers in the pharmaceutical industry engaged in drug development.
Download or read book Pharmacology of the Skin I written by and published by Springer. This book was released on 2011-12-21 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent interest in the pharmacology of the skin and the treatment of its diseases has come about for two reasons. The first is a realisation that many aspects of pharmacology can be studied as easily in human skin, where they may be more relevant to human physiology and diseases, as in animal models. Examples of this are the action of various vasoactive agents and the isolation of mediators of inflammation after UV irradiation and antigen-induced dermatitis. The second reason is the fortuitous realisation that a pharmacological approach to the treatment of skin disease need not always await the full elucidation of etiology and mechanism. For example, whilst the argument continued unresolved as to whether the pilo-sebaceous infection which constitutes acne was due to a blocked duct or to a simple increase in sebum production, 13-cis-retinoic acid was found quite by chance totally to ablate the disease; again, whilst cyclosporin, fresh from its triumphs in organ transplantation, has been found able to suppress the rash of psoriasis, it has resuscitated the debate on etiology. We are therefore entering a new era in which the pharmacology and clinical pharmacology of skin are being studied as a fascinating new way of exploring questions of human physiology and pharmacology as well as an important step in the development and study of new drugs, use of which will improve disease control and at the same time help to define pathological mechanisms.
Download or read book Pharmacology of the Skin II written by D J Atherton and published by . This book was released on 1989-08-24 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pharmacology and clinical pharmacology of skin are being studied as a fascinating new way of exploring questions of human physiology and pharmacology, and as an important step in the development of new drugs. Detailed information which can be used as a basis for further study in this attractive field is now available for the first time. This is the second of two independent, yet complementary, volumes which form one complete work on the pharmacology of the skin. It provides academic and industrial researchers and clinicians with an integrated approach to the subject so that both the experienced worker and those new to the field can gain up-to-date insight in all the relevant topics. While Volume I covers the general pharmacology of the skin, Volume II is concerned with disease and drugs. It discusses methods of measuring the response of skin to drugs; toxicology, including drug metabolism in the skin and absorption by it; and specific drugs acting on the skin and drugs used for specific diseases. Throughout both volumes, the most recent advances on clinical pharmacological aspects of study in the field are presented.
Download or read book Pharmacology of the Skin I written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent interest in the pharmacology of the skin and the treatment of its diseases has come about for two reasons. The first is a realisation that many aspects of pharmacology can be studied as easily in human skin, where they may be more relevant to human physiology and diseases, as in animal models. Examples of this are the action of various vasoactive agents and the isolation of mediators of inflammation after UV irradiation and antigen-induced dermatitis. The second reason is the fortuitous realisation that a pharmacological approach to the treatment of skin disease need not always await the full elucidation of etiology and mechanism. For example, whilst the argument continued unresolved as to whether the pilo-sebaceous infection which constitutes acne was due to a blocked duct or to a simple increase in sebum production, 13-cis-retinoic acid was found quite by chance totally to ablate the disease; again, whilst cyclosporin, fresh from its triumphs in organ transplantation, has been found able to suppress the rash of psoriasis, it has resuscitated the debate on etiology. We are therefore entering a new era in which the pharmacology and clinical pharmacology of skin are being studied as a fascinating new way of exploring questions of human physiology and pharmacology as well as an important step in the development and study of new drugs, use of which will improve disease control and at the same time help to define pathological mechanisms.
Download or read book Systemic Drugs for Skin Diseases written by Stephen E. Wolverton and published by . This book was released on 1991 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Definitive text covering the clinical pharmacology of systemic drugs in dermatology. Topics include drugs for infectious diseases, antiviral, antifungal, and antibacterial agents, immunomodulatory agents, and more.
Download or read book Pharmacology of the Skin II written by and published by Springer. This book was released on 2012-02-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent interest in the pharmacology of the skin and the treatment of its diseases has come about for two reasons. The first is a realisation that many aspects of pharmacology can be studied as easily in human skin as in animal models, where they may be more relevant to human physiology and disease. Examples of this are the action of various vasoactive agents and the isolation of mediators of inflammation after UV irradiation and antigen-induced dermatitis. The second reason is the fortuitous realisation that a pharmacological approach to the treatment of skin disease need not always await the full elucidation of aetiology and mechanism. For example, whilst the argument continued un resolved as to whether the pilo-sebaceous infection which constitutes acne was due to a blocked duct or to a simple increase in sebum production, 13-cis retinoic acid, was found quite by chance totally to ablate the disease; again, whilst cyclosporin, fresh from its triumphs in organ transplantation, has been found able to suppress the rash of psoriasis, it has resuscitated the debate on aetiology. We are therefore entering a new era in which the pharmacology and clinical pharmacology of skin are being studied as a fascinating new way of exploring questions of human physiology and pharmacology as well as for the development and study of new drugs, use of which will improve disease control and at the same time help to define pathological mechanisms.
Download or read book Pharmacology and the Skin written by and published by . This book was released on 1987 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pharmacology and the Skin written by William Montagna and published by . This book was released on 1972 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cellular Pharmacology of the Skin written by and published by . This book was released on 1986 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds written by Kenji Sugibayashi and published by Springer. This book was released on 2017-11-28 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews skin permeation and disposition of chemical compounds. Skin is utilized as an administration site for transdermal drug delivery systems, topical drug formulations, cosmeceuticals, and cosmetics. Their usefulness is closely related to the permeation and disposition of entrapped active ingredients through and into the skin. Skin permeation, disposition, and metabolism of chemicals are first summarized in the general introduction. Then primary topical formulations are explained in the second part, “Basic Formulations Applied to Skin”. The explanation for the active compounds and formulations are of the most important parts required to fabricate these formulations. Skin absorption of chemicals is generally much lower than oral and the other mucosal absorptions, so that skin-penetration enhancement is a key issue to have good formulations topically applied. Part 3 presents “Skin Penetration Enhancement”. In addition, Part 4, “Selection of Topically Applied Chemical Candidates”, deals with selection methods of topically applied ingredients for transdermal drug delivery systems, topical drug formulations, cosmeceuticals, and cosmetics. Parts 5 and 6, “Safety Assessment of Topically Applied Compounds“ and “Experimental Methods of Skin Permeation“, respectively, show safety issues and experimental methods for topical formulations. The final part consists of comments on therapeutic and cosmetic formulations by medical doctors and pharmacists. Their comments are especially helpful for pharmaceutical and cosmetic researchers who study dermatopharmacokinetics and topical formulations. This volume is particularly useful for those working in R&D, graduate students, and educators in the area of pharmaceutics, cosmetic sciences, dermatological sciences, pharmacology, toxicology, biopharmacy, pharmacokinetics, physical pharmacy, chemical engineering, and related fields.
Download or read book Pharmacology of Retinoids in the Skin written by Uwe Reichert and published by . This book was released on 1989 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Systemic Drug Treatment in Dermatology written by Sarah H. Wakelin and published by CRC Press. This book was released on 2023-02-13 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Systemic Drug Treatment in Dermatology helps prescribers and patients make rational decisions about drug treatment while considering known risks and potential unwanted effects. Written for dermatologists, family practitioners, pharmacists and specialist nurses, this completely revised and updated third edition of a bestseller provides an accessible and concise aid to prescribing and monitoring systemic dermatologic therapy. For each drug or drug class, the book lists its classification, mode of action, formulations, dosages, suggested regimens, contraindications, important drug interactions, adverse effects, patient information, and more. This third edition includes new classes of drugs as well as information on updated guidelines for prescribing and monitoring established drugs. FROM REVIEWS OF PREVIOUS EDITIONS "This updated edition includes new arrivals... Quite simply, it is indispensable! I have it with me in every clinic and often refer to it in discussions with pharmacists (who have been known to borrow my copy and forget to return it)." Dermatology in Practice "... an outstanding resource that helps to alleviate worrying by providing precise guidelines and advice in managing our most infirm patients who require these medications." SkinMed
Download or read book Comprehensive Dermatologic Drug Therapy written by Stephen E Wolverton and published by Elsevier Health Sciences. This book was released on 2019-12-14 with total page 1073 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed with practical usability in mind, Comprehensive Dermatologic Drug Therapy, 4th Edition, helps you safely and effectively treat the skin disorders you're likely to see in your practice. Dr. Stephen E. Wolverton and new associate editor Dr. Jashin J. Wu lead a team of global experts to bring you concise, complete guidance on today's full spectrum of topical, intralesional, and systemic drugs. You'll prescribe with confidence thanks to expert coverage of which drugs to use, when to use them, and adverse effects to monitor. - Includes new drug interaction tables, drug risk profiles, and FDA guidelines, as well as two new appendices that summarize chapter questions and summarize highest-risk drug interactions. - Covers the best uses for new biologic therapeutics. - Contains new chapters covering medical decision-making principles, PDE-4 and JAK inhibitors, interleukin 17 inhibitors, interleukin 23 inhibitors, additional biologic therapeutics, and hedgehog pathway inhibitors. - Contains quick-access summaries of indications/contraindications, dosage guidelines, drug interactions, drug monitoring guidelines, adverse effects, and treatment protocols. - Features a highly detailed, disease-specific index, as well as purchase information for major drugs. - Helps you assess your knowledge and prepare for certification or recertification with about 800 review questions and answers throughout the book. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Download or read book Pharmacology and the Skin written by William Montagna and published by . This book was released on 1972 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book pH of the Skin Issues and Challenges written by C. Surber and published by Karger Medical and Scientific Publishers. This book was released on 2018-08-21 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of expressing acidity as the negative logarithm of the hydrogen ion concentration was defined and termed pH in the beginning of the 20th century. The general usefulness of the pH concept for life science was recognized and later gained importance to analytical research. Reports on results of pH measurements from living skin established the term acid mantle - the skin's own protective shield that maintains a naturally acid pH. It is invisible to the eye but crucial to the overall wellbeing of skin. Chronic alkalization can throw this acid mantle out of balance, leading to inflammation, dermatitis, and atopic skin diseases. It is therefore no surprise, that skin pH shifts have been observed in various skin pathologies. It is also obvious that the pH in topically applied preparations may play an important role. Optimal pH and buffer capacity within topical preparations not only support stability of active ingredients and auxiliary materials, but may also increase absorption of the non-ionized species of an acidic or a basic active ingredient. They may even open up opportunities to modify and "correct" skin pH and hence accelerate barrier recovery and maintain or enhance barrier integrity. Further efforts are needed to standardize and improve pH measurements in biological media or pharmaceutical/cosmetic vehicles to increase and ensure quality, comparability, and relevance of research data. In this volume, we present a unique collection of papers that address past, present and future issues of the pH of healthy and diseased skin. It is hoped that this collection will foster future efforts in clinical and experimental skin research.
Download or read book Comprehensive Dermatologic Drug Therapy written by Stephen E Wolverton, MD and published by Elsevier Health Sciences. This book was released on 2012-11-16 with total page 1015 pages. Available in PDF, EPUB and Kindle. Book excerpt: Safely and effectively treat a full range of skin disorders with Comprehensive Dermatologic Drug Therapy, 3rd Edition! This trusted dermatology reference provides concise, complete, up-to-date guidance on today's full spectrum of topical, intralesional, and systemic drugs. Dr. Steven E. Wolverton and a team of leading international experts clearly explain what drugs to use, when to use them, and what to watch out for. Prescribe with confidence thanks to quick-access summaries of indications/contraindications, dosage guidelines, drug interactions, drug monitoring guidelines, adverse effects, and treatment protocols. Assess your knowledge and prepare for certification or recertification with more than 800 review questions and answers throughout the book. Contain costs and meet patient expectations with purchase information provided for major drugs. Quickly evaluate drug options for each disease discussed using a highly detailed, disease-specific index. Discover the best uses for new biologic therapeutics such as ustekinumab and rituximab, as well as newly improved TNF inhibitors. Offer your patients the very latest in cosmetic procedures, including chemical peels, intradermal fillers, and botulinum toxin. Use the safest and most effective drugs possible with new chapters on irritants and allergens in topical therapeutic agents, plus a new, separate chapter on mycophenolate mofetil. Review drugs recently taken off the market by the FDA, and use that knowledge to improve your current dermatologic drug therapy. Access the complete contents online at www.expertconsult.com and perform rapid searches for drug indications, interactions, monitoring guidelines, and much more.
