Download or read book Pharmaceutical Chemistry of Antihypertensive Agents written by Gyorgy Szasz and published by CRC Press. This book was released on 1990-12-19 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical Chemistry of Antihypertensive Agents, provides the only comprehensive treatment of anti-hypertensive properties (e.g., structure-activity relationship, analytics, and metabolism) of pharmaceutical chemicals. The topics discussed include diuretics, renin inhibitors, angiotensin-converting enzyme inhibitors, a-blocking agents, b-adrenergic antagonists, and vasodilators. Data is supported by more than 1400 references and 300 chemical structures. This book is essential reading for physicians and pharmaceutical researchers, as well as pharmaceutical chemistry students.

Download or read book Antihypertensive Agents written by Edward L. Englehardt and published by . This book was released on 1976 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past quarter of a century, there has been a continuing trend by the clinician to use antihypertensive therapy in patients with less and less severe hypertensive disease. This has led to a need for agents that are effective in milder degrees of hypertension and substantially free from side effects that might reduce compliance of the patient with the therapeutic regimen. The four papers that comprise this volume provide a concise overview of the current status of antihypertensive agents in use or in the later stages of development in 1975. The development of new agents to permit better control of blood pressure while restoring normal hemodynamics with minimal side effects presents a continuing challenge to the medicinal chemist. Doubtless improved agents that fall into the pharmacological classes now recognized will be developed. The complexity of the interplay of neural and renal factors involved in the control of blood pressure gives hope that other points for therapeutic intervention will be found as our basic knowledge of the pathophysiology of hypertensive vascular disease increases. - from the preface.

Download or read book Antihypertensive Drugs written by Zweten and published by CRC Press. This book was released on 1997-09-05 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twenty US and European contributors from academia and pharmaceutical companies present a tripartite discussion of the short but impressive history of drug treatment of essential hypertension, focusing on: medicinal chemistry, pharmacology, and the clinical picture. Each successive generation of drugs (e.g. beta-blockers, calcium antagonists, and ACE-inhibitors) permits more precise tailoring to individual patient needs, as well as further elucidating the pathophysiology of the disease. Those interested in integrative medicine will appreciate the paper on treating hypertension in the elderly and diabetics, which refers to non-drug lifestyle approaches to lowering blood pressure. Annotation copyrighted by Book News, Inc., Portland, OR

Download or read book Antihypertensive Agents written by and published by . This book was released on 1976 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Antihypertensive Agents written by Emil Schlittler and published by . This book was released on 1967 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Drug Design written by Everhardus Jacobus Ariëns and published by . This book was released on 1971 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Molecular Modification in Drug Design written by American Chemical Society. Division of Medicinal Chemistry and published by . This book was released on 1964 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Pharmaceutical Chemistry VI written by and published by Krishna Prakashan Media. This book was released on with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Medicinal Chemistry of the Renin angiotensin System written by P. B. M. W. M. Timmermans and published by Elsevier Science & Technology. This book was released on 1994 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text reviews recent aspects of the renin-angiotensin system with a focus on the medicinal chemistry of the drugs interfering with this system. It also covers the development of nonpeptide angiotensin II receptor antagonists.

Download or read book Drug Design written by E. J. Ariëns and published by Elsevier. This book was released on 2013-10-22 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Design, Volume X covers promising and current developments in drug design. The book discusses procedures as applied in the practice of drug design; the structural aspects of the structure-activity relationships of neuroleptics; and promising perspectives in the highly actual field of bioactive peptides. The text also describes the application of the dynamic systems analysis to the antihypertensive drug action; polymeric drug delivery systems; and the design of biocompatible polymers. The structure-activity relationships of insect repellents as a basis for the design of such agents, as well as the approaches to the multivariate data analysis in structure-activity relationships, which is an essential aspect of drug design, are also encompassed. Chemists, pharmacologists, bioengineers, and people involved in drug design and manufacture will find the book invaluable.

Download or read book ANTIHYPERTENSIVE AGENTS PAPERS PRESENTED AT A SYMPOSIUM HELD DURING THE 169TH MEETING OF THE AMERICAN CHEMICAL SOCIETY DIVISION OF MEDICINAL CHEMISTRY ACS written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chemical Factors in Hypertension written by American Chemical Society. Division of Medicinal Chemistry and published by . This book was released on 1950 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Antihypertensive Drugs Today written by R.N. Brogden and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Burger s Medicinal Chemistry and Drug Discovery Therapeutic Agents written by Manfred E. Wolff and published by Wiley-Interscience. This book was released on 1996-04-26 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most comprehensive source of the latest information in drug discovery and medicinal chemistry BURGER'S MEDICINAL CHEMISTRY AND DRUG DISCOVERY, FIFTH EDITION, Volume 2: Therapeutic Agents Renowned for its incisive, systematic examination of the new classes of drugs, Burger's Medicinal Chemistry and Drug Discovery provides professionals with thorough, yet selective access to drug chemistry information in a convenient format. Volume 2 outlines the newest generation of drugs with the potential for controlling cardiovascular, gastrointestinal, and tubercular disease. These include: * Cholinergics and anticholinergics * Gastric proton pump inhibitors * Cardiac drugs and antihypertensive agents * Diuretic and urcosuric agents * Aminoglycoside, macrolide, glycopeptide, and other antibacterial antibiotics * Antimycobacterial and antifungal agents The behavior of each drug class is explored in terms of pathophysiology of the disease state, molecular mechanism of action, pharmacokinetics, toxicity, drug metabolism, and structure activity relationships. Special attention is given to fertile areas of further research. Burger's Medicinal Chemistry and Drug Discovery, Volume 2 is an essential reference for medical professionals and researchers working today. Burger's Medicinal Chemistry, Fifth Edition consists of five volumes: Volume 1: Principles and Practice (0-471-57556-9) 1995 " . . . an essential addition to the libraries of any medicinal chemist . . . an outstanding work . . . highly praised as a fountain of information in drug studies and research."--Journal of Medicinal Chemistry * Volume 2: Therapeutic Agents (0-471-57557-7) 1996 * Volume 3: Therapeutic Agents (0-471-57558-5) 1996 * Volume 4: Therapeutic Agents (0-471-57559-3) 1997 * Volume 5: Therapeutic Agents (0-471-57560-7) 1997

Download or read book Neurocritical Care Pharmacotherapy written by Eelco F. M. Wijdicks and published by Oxford University Press. This book was released on 2018 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurocritical Care Pharmacotherapy: A Clinican's Guide is a practical, succinct but comprehensive pharmacy handbook provides up-to-date clinical guidance on the effective selection, prescription, and usage of neurocritical care drugs for patients with acute neurologic illnesses. The treatment of the critically ill neurologic patient is often difficult, specialized, and includes drugs infrequently used in other intensive care units such as antiepileptic drugs, osmotic agents or acute immunotherapy such as intravenous immunoglobulin and plasma exchange. This text discusses choosing the right combination of drugs; how to correctly prescribe and administer the drugs; how to monitor drug efficacy and side effects; how neurocritical care drugs interact with other medications; and comprehensive coverage of current treatment options. Key Feature of this Manual Include - A brief discussion of the basic pharmacology of each neurocritical drug, with an emphasis on how to select and use these drugs in multiple clinical contexts. - 150 drugs accompanied by a diagram for quick comprehension and drug administration guides. - Unique blending of expertise of neurointensivist with a critical care pharmacist to provide a vital resource for both specialities - References for further reading that are oriented toward utility in clinical practice.

Download or read book Piperidine Based Drug Discovery written by Ruben Vardanyan and published by Elsevier. This book was released on 2017-06-12 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Piperidine-Based Drug Discovery outlines the complexities of Piperidine scaffold use in drug discovery, including derivative chemistry, structural properties, methods of synthesis and practical implementations. Piperidine scaffolds are the cornerstones of over 70 commercialized drugs (including multiple blockbusters). Designed as a guide for both experts and students working in this and related areas, it is hoped that this volume will encourage and inspire the continued design and development of novel pharmaceuticals based on Piperidine and its derivatives. Heterocyclic compounds are of central importance to medicinal chemistry, as demonstrated by the high percentage of marketable drugs that feature heterocyclic fragments in their structures. As starting points for drug discovery they offer a broad range of attractive properties, and a detailed understanding of the particular characteristics of each is of great benefit to researchers. The most commonly used heterocycle among US FDA approved pharmaceuticals, Piperidine is an extremely important building block in the synthesis of medicinal agents. This heterocycle and its derivatives exhibit a number of important functionalities and have been employed variously as CNS modulators, antiaggregants, anticoagulants, antihistamines, anti-cancer drugs and analgesics. Explores this extremely important heterocycle to a high level of detail Describes synthesis methods for 70 current drugs based on Piperidine scaffolds Gives drug designers all the key knowledge required to develop new drugs utilizing Piperidine Provides pharmacologists a solid overview of the chemical background of existing Piperidine-based drugs

Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.