Download or read book PET based Approach to Treatment Planning Systems An Improvement Towards Successful Boron Neutron Capture Therapy BNCT Essential for Energy and Health HFR High Flux Reactor Reactor Applications written by and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book PET based Approach to Treatment Planning Systems written by Guiseppe G. Daquino and published by . This book was released on 2003 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Boron Neutron Capture Therapy written by Detlef Gabel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The European Collaboration on Boron Neutron Capture Therapy (BNCT), conceived in 1987 and successful in 1989 in gaining financial support as a Concerted Action through the Medical and Health Research Programme of the Commission ofthe European Communities (CEC) in Brussels, considered it an opportune moment to hold its annual Plenary Meeting on 18-20 Septem ber 1991 as an International Workshop entitled "Towards Clinical Trials of Glioma with BNCT". The background to this consideration was influenced by the world-wide resurgence ofinterest in NCT over the last 2 decades and by the exemplifica tions at the Fourth International Symposium on Neutron Capture Therapy for Cancer held in Sydney in December 1990, where it was strongly indicated that within the next 2 years clinical trials would be started both in Europe and the United States. In particular at the High Flux Reactor of the Joint Research Centre of the CEC at Petten in The Netherlands, an epithermal neutron beam designed and installed in the summer of 1990 recently became operable at full reactor power. An extensive series ofexperiments, including the nuclear and radiobiological characterisation of the beam and a healthy tissue tolerance study on canines has started and has the aim to define the preconditions for clinical trials onpatients with Grade III/IV glioma. However, as with any other new therapy modality, it must be demon strated that BNCT is safe for the patient and has a reasonable chance of being an effective therapy.
Download or read book Boron Neutron Capture Therapy Treatment Planning Improvements written by John Timothy Goorley and published by . This book was released on 1998 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A PET based Treatment Planning System to Evaluate the Influence of the Heterogeneous Boron written by Giuseppe Giovanni Daquino and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Minimizing Gamma Exposure During Boron Neutron Capture Therapy Treatment at PSBR Using MCNP written by Jackson Buchko and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Boron neutron capture therapy (BNCT) is a form of targeted radiotherapy meant to selectively deliver high amounts of energy to tumor cells while being more likely to spare healthy tissue than traditional forms of cancer treatment. This method of cancer treatment uses a stable isotope of boron, 10B, which has a high probability of absorbing a neutron, and the reaction resulting from this absorption leaves this isotope in an excited state of 11B, which ultimately fissions to produce an alpha particle. This alpha particle is what delivers the energy to the tumor, and the fact that these particles do not travel far, sparing healthy tissue and making alpha particles ideal for targeted radiotherapy. The issue is that neutron sources, such as the Penn State Breazeale Reactor (PSBR), also produce gamma radiation in addition to neutrons, exposing patients to additional, unwanted radiation. The aim of this project was to help combat patient exposure to gamma radiation from the neutron source used during boron neutron capture therapy (BNCT). A model of Neutron Beam Port 4 (NBP4) at the PSBR was created in MCNP to help accomplish this goal. This model was created to execute simulations involving the neutron beam port used in the BNCT procedure. From this model execution, neutron and photon flux profiles were determined at varying axial and radial locations along the beam port. The results of these calculations were then to be used to make recommendations towards the implementation of some shielding geometry in NBP4 for BNCT procedures. This model was originally to be executed under four conditions: no shielding, and gamma ray shielding made of concrete, steel, and lead. Future work is recommended to achieve more detailed MCNP model results.
Download or read book A Patient Specific Treatment Planning Method for BNCT Utilizing MCNP and RayStation written by James M. Seekamp and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current boron neutron capture therapy (BNCT) treatment planning systems compute dose is several different ways. Many of these systems have chosen Monte Carlo N-Particle (MCNP) as their dose engine due to its widespread usage and verified results. Several of the MCNP based treatment planning systems use standard DICOM computed tomography (CT) files to voxelize and create the patient specific model in MCNP. From this point on boron concentrations must be assigned by tissue type. All bone in the model has the same boron concentration, all healthy tissue will be set to one concentration, and the target volume will be set to a different spatially homogeneous concentration. This work seeks to address these assumptions about boron concentration by also integrating positron emission tomography (PET) information into the model so that each voxel in the model has the correct boron concentration. This step improves the accuracy of the patient specific model which improves the accuracy of dose calculations. that this method is creating a patient specific model with non-homogeneous boron concentration and that the calculated dose distribution is reasonable. This method was also developed to use RayStation as its visual display interface to visualize doses, volumes, and dose volume histograms due its ease of use.
Download or read book Neutron Capture Therapy written by Wolfgang A.G. Sauerwein and published by Springer Science & Business Media. This book was released on 2012-11-05 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neutron capture therapy (NCT) is based on the ability of the non-radioactive isotope boron-10 to capture thermal neutrons with very high probability and immediately to release heavy particles with a path length of one cell diameter, which in principle allows for tumor cell-selective high-LET particle radiotherapy. This book provides a comprehensive summary of the progress made in NCT in recent years. Individual sections cover all important aspects, including neutron sources, boron chemistry, drugs for NCT, dosimetry, and radiation biology. The use of NCT in a variety of malignancies and also some non-malignant diseases is extensively discussed. NCT is clearly shown to be a promising modality at the threshold of wider clinical application. All of the chapters are written by experienced specialists in language that will be readily understood by all participating disciplines.
Download or read book Utilization Related Design Features of Research Reactors written by International Atomic Energy Agency and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 50 years research reactors have played an important role in the development of nuclear science and technology. They have made significant contributions to a large number of disciplines, as well as to the educational and research programmes of about 70 countries worldwide. There are substantial utilization issues being faced by the research reactor community, including the selection, design and operation of various types of devices in research reactors. This publication has been prepared by the IAEA to facilitate the exchange of ideas, concepts and experience. It presents descriptions of design and utilization features of facilities and associated devices that are implemented in different research reactors worldwide, covering selected fields of application.
Download or read book Dorland s Dictionary of Medical Acronyms and Abbreviations E Book written by Dorland and published by Elsevier Health Sciences. This book was released on 2015-07-24 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical acronyms and abbreviations offer convenience, but those countless shortcuts can often be confusing. Now a part of the popular Dorland’s suite of products, this reference features thousands of terms from across various medical specialties. Its alphabetical arrangement makes for quick reference, and expanded coverage of symbols ensures they are easier to find. Effective communication plays an important role in all medical settings, so turn to this trusted volume for nearly any medical abbreviation you might encounter. Symbols section makes it easier to locate unusual or seldom-used symbols. Convenient alphabetical format allows you to find the entry you need more intuitively. More than 90,000 entries and definitions. Many new and updated entries including terminology in expanding specialties, such as Nursing; Physical, Occupational, and Speech Therapies; Transcription and Coding; Computer and Technical Fields. New section on abbreviations to avoid, including Joint Commission abbreviations that are not to be used. Incorporates updates suggested by the Institute for Safe Medication Practices (ISMP).
Download or read book Beneficial Uses and Production of Isotopes written by OECD Nuclear Energy Agency and published by Nuclear Energy Agency. This book was released on 1998 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is the first international survey on the beneficial uses and production of isotopes. It provides an overview of their main uses, and detailed information on the facilities that produce them world-wide.
Download or read book Intense Neutron Sources written by U.S. Atomic Energy Commission and published by . This book was released on 1966 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dictionary of Medical Acronyms and Abbreviations written by Stanley Jablonski and published by Hanley & Belfus. This book was released on 2004-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dictionary lists acronyms and abbreviations occurring with a reasonable frequency in the literature of medicine and the health care professions. Abbreviations and acronyms are given in capital letters, with no punctuation, and with concise definitions. The beginning sections also include symbols, genetic symbols, and the Greek alphabet and symbols.
Download or read book Advances in Neutron Capture Therapy written by R.F. Barth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: Binary systems for the treatment of cancer potentially are among the most attractive of the new therapeutic modalities that currently are under investigation. The basicconcept is to selectivelydestroy malignantcells whileconcomitantlysparing normal tissue. Neutron capture therapy (NCT) is the binary system that has been the subject of the Fifth International Symposium on Neutron Capture Therapy, which was held September13-17, 1992, in Columbus, Ohio, undertheauspicesoftheInternational Society for Neutron Capture Therapy. Its objective was to bring together researchers from throughout the world and to provide a forum at which they could present the latest advances in the development of Neutron capture therapy. Neutron capture therapy has largely, but not exclusively, focused on the use of boron-10 as the target nuclide. Boron neutron capture therapy (BNCT) is based on the nuclear reaction that occurs when the stable isotope, boron-10, absorbs low-energy non ionizing thermal neutrons to yield alphaparticles and recoiling lithium-7 nuclei. The size and energy of these high linear energy transfer (LET) particles result in their being confined largely to the cells in which the capture reaction occurs. For BNCT to be successful, a sufficient numberof I~atoms mustbe localized within neoplastic cells, and enough thermal neutrons must be delivered and absorbed by the I~ to produce a lethal 1~(n,QVLi reaction. Two major problems must be surmounted.
Download or read book Cancer Neutron Capture Therapy written by Y. Mishima and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 893 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are many human cancers which actively synthesize specific characteristic proteins such as melanomas, thyroid cancer and squamous cell carcinoma. Many cancer researchers have of course tried to utilize this specific activity as a key for the selective treatment of cancers. In the past for example, the molecular hybrid compound of DOPA, a substrate of melanin, and nitrogen mustard N-oxide hydrochloride, a ctyotoxic anti-tumor drug, was synthesized as Melphalan and used to treat malignant melanoma. A major problem arose though in that it was soon found to be highly suppressive toward bone marrow and quite toxic while not being remarkably effective. Thus, malignant melanoma could not be cured by it. Such failure led us to develop a novel bimodal therapeutic system which includes the use of non-toxic potentially cytocidal chemicals which selectively accumulate within the cancer cells and which are converted by a controllable modality into an actively cytocidal element in situ. We can now non-surgically cure malignant melanoma and glioblastoma with our selective cancer treatment, neutron capture therapy (NCT); as can be found in this volume. Included are 124 papers on the latest breaking developments discussed at the Sixth International Symposium on NCT for Cancer held in Kobe during the late autumn of 1994.
Download or read book New Nuclear Data written by and published by . This book was released on 1957 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Reactor Core Materials written by and published by . This book was released on 1960 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:
