Download or read book Perspectives for the Next Generation of Virus Research Spearheading the Use of Innovative Technologies and Methodologies written by Takatoki Yamamoto and published by Frontiers Media SA. This book was released on 2017-07-06 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are associated with approximately 20% of global mortality, with viral diseases causing about one third of these deaths. Besides newly emerging and re-emerging viral infections will continue to pose a threat to human survival globally. In this case scientific advances have greatly been increased to defend against those pathogens. For example, rapid genomic sequencing, proteomics, epigenomics, nanotechnology, and other advanced tools are being applied to detect viruses at the point of care and to track their spread within human populations as well as to understand virus-host interaction and virus induced pathogenesis. From rapid identification of new viruses to prevention with vaccination and treatment with effective therapeutics, biomedical research has continuously provided tools to meet the constant threat of emerging viral pathogens. Despite these advances, each new disease brings unique challenges to scientists every year. So we must stay at the cutting edge of scientific discovery, working energetically to develop new tools to combat the ever-changing threats they pose. Our research topic highlights such advanced and new technology based virus research which definitely bolsters the researcher's ability to tackle emerging, re-emerging and stable viral pathogens. We are credulous that the papers including in the e-books will be beneficial to the experts in the field to understand the molecular, immunological, ecological and clinical aspects of the next generation researches for the prevention and control of infectious diseases caused by viruses.
Download or read book Coronavirus Disease 19 COVID 19 A Perspective of New Scenario written by Kamal Niaz and published by Bentham Science Publishers. This book was released on 2021-09-16 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: COVID-19: Epidemiology, Biochemistry, and Diagnostics explains COVID-19 from multidisciplinary angles such as the evolution of SARS-COV, genetic techniques to study the virus, and diagnostic methodologies widely used in the global COVID-19 pandemic. The chapters in this book provide the reader with up-to-date literature about research on SARS-CoV-2 through three parts: I) Evolution and Entry of SARS-CoV-2 into the host II) Genetic Alteration and Structural Determination of SARS-CoV-2 Proteins III) Quantitative Analysis of SARS-CoV-2 for research and medical diagnosis Key Features: - 15 chapters on SAR-CoV-2 in a multidisciplinary context - Provides a comprehensive overview of SARS-CoV-2 evolution and genetics - Provides biochemical information about SARS-CoV-2 proteins and receptor targets (both structural and non-structural proteins) - Includes an overview of several methods of detecting SARS-CoV-2 virus particles (ELISA, PCR, Neutralizing Antibodies - Covers some critical diagnostic modalities for COVID-19 diagnosis - Provides bibliographic references for further reading Readers will understand the significance of phylogenetic analysis of coronaviruses, along with the pathogenesis of COVID-19 and related diseases such as SARS and MERS. Applications of biochemical technologies such as RT-PCR and CRISPR are also demonstrated in the text. This book is a comprehensive introduction to COVID-19 research for medical researchers, microbiologists and virologists. Students in academic programs in life sciences and medicine will also benefit from the information provided in the book.
Download or read book Omics Approaches and Technologies in COVID 19 written by Debmalya Barh and published by Academic Press. This book was released on 2022-12-01 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The COVID-19 pandemic has affected the entire world in an unprecedented way since 2019. However, novel and innovative applications of various omics, computational, and smart technologies have helped manage the pandemic of the 21st century in a very effective manner. Omics approaches and technologies in COVID-19 presents up-to-date knowledge on omics, genetic engineering, mathematical and computational approaches, and advanced technologies in the diagnosis, prevention, monitoring, and management of COVID-19. This book contains 26 chapters written by academic and industry experts from more than 15 countries. Split into three sections (Omics; Artificial Intelligence and Bioinformatics; and Smart and Emerging Technologies), it brings an overview of novel technologies under omics such as, genomic, metagenomic, pangenomic, metabolomics and proteomics in COVID-19. In addition, it discusses hostpathogen interactions and interactomics, management options, application of genetic engineering, mathematical modeling andsimulations, systems biology, and bioinformatics approaches in COVID-19 drug discovery and vaccine development. This is a valuable resource for students, biotechnologists, bioinformaticians, virologists, clinicians, and pharmaceutical, biomedical, and healthcare industry people who want to understand the promising omics and other technologies used in combating COVID-19 from various aspects. Provides novel technologies for rapid diagnostics, drug discovery, vaccine development, monitoring, prediction of future waves, etc. Describes various omics applications including genomics, metagenomics, epigenomics, nutrigenomics, transcriptomics,miRNAomics, proteomics, metabolomics, phenomics, multiomics, etc., in COVID-19 Presents applications of genetic engineering, CRISPR, artificial intelligence, mathematical and in silico modeling, systems biology,and other computational approaches in COVID-19 Discusses emerging, digital, and smart technologies for the monitoring and management of COVID-19
Download or read book Covid 19 Biomedical Perspectives written by and published by Academic Press. This book was released on 2022-05-31 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covid-19: Biomedical Perspectives, Volume 50 in the Methods in Microbiology series highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Individual chapters in this new release include Sensitive methods for detection of SARS-CoV-2 RNA, Treatment of COVID-19 using Chinese herbal medicine, Understanding how SARS-CoV-2 is evolving and its impact on COVID-19 animal models and vaccine evaluation, Methods in machine learning to identify COVID-19 literature, COVID-19 seasonal behavior and the mutational landscape of the SARS-CoV-2 virus, CRISPR use in Diagnosis and Therapy for COVID-19, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods of Microbiology serials Updated release includes the latest information on Covid-19: Biomedical Perspectives
Download or read book Improving Viral Pathogen Discovery Characterization and Surveillance Through High throughput Antibody Screening Methods written by Anna Siobhan Heffron and published by . This book was released on 2021 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Six Public Health Emergencies of International Concern have been declared since the establishment of the World Health Organization (WHO)'s Emergency Committee in 2005. These emergencies were all viral diseases: pandemic H1N1 influenza in 2009, poliovirus resurgence in 2014, the outbreak of Ebola in West Africa in 2014, the emergence of Zika virus in the Americas in 2016, another Ebola outbreak in central Africa in 2018, and most recently the emergency of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the coronavirus disease of 2019 (COVID-19) pandemic. With the exception of poliovirus, most of these are zoonotic, vector-borne, or both. Without exception, the human response to these emergences has been reactive, perpetually caught by surprise by these outbreaks and often forced to start from a place of catching up with the developments of these new or newly-emerging viral pathogens. The increasing frequency of these emergences demonstrates the need for ready pathways for rapid development of diagnostic, preventive, and treatment modalities, and they further demonstrate the need for better viral surveillance and virus discovery systems, so that we might not be caught quite so unaware with the next viral emergence. Efforts at an efficient, effective response to each recent viral emergence has been hindered by a lack of rapid, accessible and accurate diagnostic testing and prepared, easily adaptable medical countermeasures. In this thesis, I combine a variety of microbiology techniques-including microscopy, use of animal models, polymerase chain reaction, enzyme-linked immunosorbent assays, and neutralization assays-alongside the emerging and evolving technologies of NGS and ultradense peptide array analysis to probe the limits of our understanding of rapid viral discovery and characterization. By combining these technologies to study novel viruses and viruses emerging to cause new disease, my work aims to provide a window into how future emerging infectious threats may be more effectively detected and characterized. In chapter 2, we use next generation sequencing and novel virus discovery computational methods to investigate a potential infectious cause for an increased rate of lymphocytic enterocolitis in common marmosets at the Wisconsin National Primate Research Center. In chapter 3, we use a macaque model to test and develop a novel ultradense peptide microarray to discern the cross-reactivity and the unique aspects of close-related flaviviruses. In chapter 4, using similar technology and bioinformatic pipelines to those in chapter 3, we are able to apply the technology developed in chapter 3 to the emerging viral threat SARS-CoV-2. Building upon the work presented here will increase our understanding of and capacity to detect and combat current and future emerging pathogens.
Download or read book Emerging Technologies for Battling Covid 19 written by Fadi Al-Turjman and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents recent trends and solutions to help healthcare sectors and medical staff protect themselves and others and limit the spread of the COVID-19. The book also presents the problems and challenges researchers and academics face in tackling this monumental task. Topics include: Unmanned Aerial Vehicle (UAV) or drones that can be used to detect infected people in different areas; robots used in fighting the COVID-19 by protecting workers and staff dealing with infected people; blockchain technology that secures sensitive transactions in strict confidentiality. With contributions from experts from around the world, this book aims to help those creating and honing technology to help with this global threat. Presents solutions to help healthcare sectors and medical staff protect themselves and patients and limit the spread of the COVID-19; Includes technologies that can be used to help fight COVID-19 such as UAV, deep learning, robotics, blockchain, and big data; Provides researchers, academics, professionals, and students from broad sectors with tools they need to help fight current and future viruses.
Download or read book Coronaviruses written by Helena Jane Maier and published by Humana. This book was released on 2016-10-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume aims to describe a variety of techniques that reflects the wide range of research currently performed in the field of coronavirology, and begins with an overview of current understandings of coronavirus replication and pathogenesis to introduce specialists and non-specialists to the field. The rest of the book is divided into several sections of chapters beginning with those that describe identification, diagnosis, and study of the evolution of coronaviruses. The next few chapters discuss the preparation of cells and organ cultures useful in propagating coronaviruses and titration techniques, as well as techniques for analyzing virus functions that require purification of the viruses. The next chapters describe two commonly used reverse genetics techniques for coronaviruses, and techniques detailing identification of cellular receptors, binding profiles of viral attachment proteins, and virus-cell fusion. The final chapters cover a broad spectrum of techniques to identify virus-host protein-protein interactions, confirm the functional role of these proteins in virus replication, study host cell responses through genome-wide or pathway-specific approaches, and visualize virus replication complexes. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Authoritative and practical, Coronaviruses: Methods and Protocols appeals to a wide variety of scientists because it highlights techniques that are currently used in the coronovirology field, while also discussing practices applicable to other virology fields.
Download or read book Advances in Viral Genomes Research written by Giannini Ylenia D Borrelli John a and published by . This book was released on 2014-05-14 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral diseases have an important impact on public health worldwide. New genomic technologies are providing infectious disease scientists with a unique ability to study at the genetic level those viruses that cause disease and the interactions they have with infected hosts. In this book, the authors present new research in viral genomes. Topics include improvements in HSV-1 derived amplicon vectors for gene transfer; viral genome research in papillomavirus; the synthetic synthesis of viral genomes; and a novel bioinformatic method to analyze more than 10,000 influenza virus strains simultaneously.
Download or read book Converging Technologies for Improving Human Performance written by Mihail C. Roco and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: M. C. Roco and W.S. Bainbridge In the early decades of the 21st century, concentrated efforts can unify science based on the unity of nature, thereby advancing the combination of nanotechnology, biotechnology, information technology, and new technologies based in cognitive science. With proper attention to ethical issues and societal needs, converging in human abilities, societal technologies could achieve a tremendous improvement outcomes, the nation's productivity, and the quality of life. This is a broad, cross cutting, emerging and timely opportunity of interest to individuals, society and humanity in the long term. The phrase "convergent technologies" refers to the synergistic combination of four major "NBIC" (nano-bio-info-cogno) provinces of science and technology, each of which is currently progressing at a rapid rate: (a) nanoscience and nanotechnology; (b) biotechnology and biomedicine, including genetic engineering; (c) information technology, including advanced computing and communications; (d) cognitive science, including cognitive neuroscience. Timely and Broad Opportunity. Convergence of diverse technologies is based on material unity at the nanoscale and on technology integration from that scale.
Download or read book Advances in Virus Research written by Karl Maramorosch and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Century of Innovation written by 3M Company and published by 3m Company. This book was released on 2002 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: A compilation of 3M voices, memories, facts and experiences from the company's first 100 years.
Download or read book Technology and Leadership written by Daniel J. Watola and published by . This book was released on 2017 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: “The military operates in volatile, uncertain, complex and ambiguous environments. While technology can be a solution to the problems faced by militaries, it can also be its own problem in need of a solution. Whether bane or boon, technology is not only changing who, what, where, when, and how militaries fight, but the rate of technological change is also ever-increasing. Technology and Leadership: International Perspectives, is the twelfth volume of the International Military Leadership Association Working Group (IMLAW) series published by the Canadian Defence Academy Press. In this volume, 33 authors from 8 countries offer their perspectives on the relationship between technology and leadership”--Foreword, p. v.
Download or read book Next Generation Earth System Prediction written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-08-22 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the nation's economic activities, security concerns, and stewardship of natural resources become increasingly complex and globally interrelated, they become ever more sensitive to adverse impacts from weather, climate, and other natural phenomena. For several decades, forecasts with lead times of a few days for weather and other environmental phenomena have yielded valuable information to improve decision-making across all sectors of society. Developing the capability to forecast environmental conditions and disruptive events several weeks and months in advance could dramatically increase the value and benefit of environmental predictions, saving lives, protecting property, increasing economic vitality, protecting the environment, and informing policy choices. Over the past decade, the ability to forecast weather and climate conditions on subseasonal to seasonal (S2S) timescales, i.e., two to fifty-two weeks in advance, has improved substantially. Although significant progress has been made, much work remains to make S2S predictions skillful enough, as well as optimally tailored and communicated, to enable widespread use. Next Generation Earth System Predictions presents a ten-year U.S. research agenda that increases the nation's S2S research and modeling capability, advances S2S forecasting, and aids in decision making at medium and extended lead times.
Download or read book Next Generation Sequencing written by Jerzy Kulski and published by BoD – Books on Demand. This book was released on 2016-01-14 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.
Download or read book Families Caring for an Aging America written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-11-08 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Family caregiving affects millions of Americans every day, in all walks of life. At least 17.7 million individuals in the United States are caregivers of an older adult with a health or functional limitation. The nation's family caregivers provide the lion's share of long-term care for our older adult population. They are also central to older adults' access to and receipt of health care and community-based social services. Yet the need to recognize and support caregivers is among the least appreciated challenges facing the aging U.S. population. Families Caring for an Aging America examines the prevalence and nature of family caregiving of older adults and the available evidence on the effectiveness of programs, supports, and other interventions designed to support family caregivers. This report also assesses and recommends policies to address the needs of family caregivers and to minimize the barriers that they encounter in trying to meet the needs of older adults.
Download or read book Achieving Sustainable Development and Promoting Development Cooperation written by Department of Economic & Social Affairs and published by United Nations Publications. This book was released on 2008 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of the key debates that took place during the Economic and Social Council meetings at the 2007 High-level Segment, at which ECOSOC organized its first biennial Development Cooperation Forum. The discussions also revolved around the theme of the second Annual Ministerial Review, "Implementing the internationally agreed goals and commitments in regard to sustainable development."--P. 4 of cover.
Download or read book Using Grounded Theory In Nursing written by Rita Sara Schreiber, RN, DNS and published by Springer Publishing Company. This book was released on 2001-06-06 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: ìThis uniformly fine book extends and intensifies the dialogue about grounded theory and nursing.... well-designed, well-crafted, and accessible.î --Sally A. Hutchinson, PhD, RN, FAAN ì...the torch has been passed to a new generation of grounded theorists.... The editors have assembled chapters by many of the best-known scholars in North America.î --Sandra P. Thomas, PhD, RN, FAAN What is grounded theory? How is it done? When is it most appropriate to use? Grounded theory can be the research method of choice for nurses seeking to find out how people cope with existing or potential health challenges. This book offers broad coverage of method, background, philosophical roots, and new directions for grounded theory in nursing.
