Download or read book Personalizing Treatment In IBD Hype or Reality In 2020 written by Fernando Gomollón and published by Frontiers Media SA. This book was released on 2021-07-05 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Loss of Epithelial Barrier Integrity in Inflammatory Diseases Cellular Mediators and Therapeutic Targets written by Imke Atreya and published by Frontiers Media SA. This book was released on 2022-01-28 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fibromyalgia written by Dawn A. Marcus and published by Springer Science & Business Media. This book was released on 2010-09-15 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Caring for patients with fibromyalgia requires an understanding of the complex nature of this condition. Fibromyalgia: A Practical Clinical Guide is a state-of-the-art resource designed to clarify the controversy about fibromyalgia and to provide clinicians with the latest information about its pathogenesis and clinical evaluation, as well as evidence-based guidelines for effective treatment. This comprehensive title includes fully referenced, practical information on this fast-emerging field and provides useful clinical suggestions and practical office tools for effectively managing patients. The good news for fibromyalgia patients and their healthcare providers is that a wide range of medication, non-medication, and non-traditional therapies have been proven to effectively reduce some of the most problematic and disabling fibromyalgia symptoms. Brief case vignettes help describe many of the common presentations, concerns, and complexities typically seen in fibromyalgia patients. Invaluable graphic aids -- boxes, tables, and figures – are used widely to provide quick reference for the busy clinician seeking information. In addition, clinic-proven assessment and documentation tools for evaluating and monitoring fibromyalgia symptoms and severity are provided, along with handouts for patients to provide guidance on pain management techniques, including detailed exercise and relaxation technique instructions. A unique addition to the literature, Fibromyalgia: A Practical Clinical Guide is an indispensable reference for all clinicians who care for patients with fibromyalgia.

Download or read book Concepts and Principles of Pharmacology written by James E. Barrett and published by Springer Nature. This book was released on 2019-12-24 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.

Download or read book Digital Transformation of Learning Organizations written by Christian Helbig and published by Springer Nature. This book was released on 2021 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access volume provides insight into how organizations change through the adoption of digital technologies. Opportunities and challenges for individuals as well as the organization are addressed. It features four major themes: 1. Current research exploring the theoretical underpinnings of digital transformation of organizations. 2. Insights into available digital technologies as well as organizational requirements for technology adoption. 3. Issues and challenges for designing and implementing digital transformation in learning organizations. 4. Case studies, empirical research findings, and examples from organizations which successfully adopted digital workplace learning.

Download or read book Microbiome in Human Health and Disease written by Pallaval Veera Bramhachari and published by Springer Nature. This book was released on 2021-10-18 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides an overview on how the microbiome contributes to human health and disease. The microbiome has also become a burgeoning field of research in medicine, agriculture & environment. The readers will obtain profound knowledge on the connection between intestinal microbiota and immune defense systems, medicine, agriculture & environment. The book may address several researchers, clinicians and scholars working in biomedicine, microbiology and immunology. The application of new technologies has no doubt revolutionized the research initiatives providing new insights into the dynamics of these complex microbial communities and their role in medicine, agriculture & environment shall be more emphasized. Drawing on broad range concepts of disciplines and model systems, this book primarily provides a conceptual framework for understanding these human-microbe, animal-microbe & plant-microbe, interactions while shedding critical light on the scientific challenges that lie ahead. Furthermore this book explains why microbiome research demands a creative and interdisciplinary thinking—the capacity to combine microbiology with human, animal and plant physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science.This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet in a typical immune system, and have contributed to animal and plant diversification over long evolutionary timescales. Also this book explains why microbiome research presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for human health and new strategies.

Download or read book Scientific American Nutrition for a Changing World Dietary Guidelines for Americans 2020 2025 Digital Update written by Jamie Pope and published by Macmillan Higher Education. This book was released on 2021-11-10 with total page 1892 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written and illustrated in the style of Scientific American magazine, Nutrition in a Changing World, this update includes the latest U.S. dietary guidelines.

Download or read book Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis written by Padma V. Devarajan and published by Springer Nature. This book was released on 2019-11-09 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book elaborates on drug delivery targeting via intracellular delivery, specifically through the Receptor Mediated Endocytosis (RME) approach, due to the involvement of cellular receptors in various grave diseases. Targeted delivery relies on two basic approaches, passive and active targeting. While passive targeting approaches have shown great promise, the improved selectivity achieved with active targeting approaches has resulted in significantly higher efficacy. Interestingly there are numerous strategies for active targeting, many of which are already highlighted in , Targeted Drug Delivery: Concepts and Applications. Nevertheless an exciting and practical strategy for active targeting, which could enable high intracellular delivery, is through exploitation of RME. Cells in the body express receptors to enable various physiological and biochemical processes. As a result, many of these receptors are overexpressed in pathological conditions, or newer receptors expressed due to defective cellular functioning. RME is based on exploitation of such receptors to achieve intracellular delivery. While targeted delivery can have manifold applications, in this book we focus on two major and challenging therapeutic areas; i) Cancer and ii) Infectious Diseases. Targeted Intracellular Drug Delivery by Receptor Medicated Endocytosis discusses the major receptors that are useful for targeted delivery for these afflictions. A major section of this book is dedicated to details regarding their occurrence and location, the recognition domain of the receptor, structure activity relationship of substrate /ligand for selective binding, ligands explored, antagonists for ligand binding and relevance of these aspects for therapy of cancer and infectious diseases. These facets are elucidated with the help of specific examples from academic research and also emphasize commercial products, wherever relevant. In vitro cellular models relied on for assessing receptor mediated cellular targeting and in vivo models depicting clinical efficacy are focused on in a separate section. Finally, we briefly discuss the regulatory and toxicity issues that may be associated specifically with the RME approach of intracellular drug delivery.

Download or read book What Patients Say What Doctors Hear written by Danielle Ofri, MD and published by Beacon Press. This book was released on 2017-02-07 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Can refocusing conversations between doctors and their patients lead to better health? Despite modern medicine’s infatuation with high-tech gadgetry, the single most powerful diagnostic tool is the doctor-patient conversation, which can uncover the lion’s share of illnesses. However, what patients say and what doctors hear are often two vastly different things. Patients, anxious to convey their symptoms, feel an urgency to “make their case” to their doctors. Doctors, under pressure to be efficient, multitask while patients speak and often miss the key elements. Add in stereotypes, unconscious bias, conflicting agendas, and fear of lawsuits and the risk of misdiagnosis and medical errors multiplies dangerously. Though the gulf between what patients say and what doctors hear is often wide, Dr. Danielle Ofri proves that it doesn’t have to be. Through the powerfully resonant human stories that Dr. Ofri’s writing is renowned for, she explores the high-stakes world of doctor-patient communication that we all must navigate. Reporting on the latest research studies and interviewing scholars, doctors, and patients, Dr. Ofri reveals how better communication can lead to better health for all of us.

Download or read book Gut Microbiome and Its Impact on Health and Diseases written by Debabrata Biswas and published by Springer Nature. This book was released on 2020-08-27 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive examination of the role of gut microbiome/microflora in nutrition, metabolism, disease prevention and health issues, including farm animal health and food value, and human gastrointestinal health and immunity. Indigenous microbiotas, particularly the gut microflora/microbiome, are an essential component in the modern concept of human and animal health. The diet and lifestyle of the host and environment have direct impact on gut microflora and the patterns of gut microbial colonization associated with health and diseases have been documented. Contributing authors cover the impact of gut microbiome in farm animal health, and explore the possibility of modulating the human gut microbiome with better animal products to prevent human diseases, including endemic and emerging diseases such as obesity, cancer and cardiac diseases. Dieting plan and control methods are examined, with attention paid to balance dieting with natural food and drink components. In addition, the role of gut microbiota in enteric microbial colonization and infections in farm animals is also discussed. The volume also explores the possibility of improving human health by modulating the microbiome with better food, including bio-active foods and appropriate forms of intake. Throughout the chapters, authors examine cutting edge research and technology, as well as future directions for better practices regarding emerging issues, such as the safety and production of organic food.

Download or read book Surgical Techniques in Rectal Cancer written by Giovanni Dapri and published by Springer. This book was released on 2018-02-09 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the various procedures, including surgery through the abdominal wall, through a transanal access or by the union of both, using an open, laparoscopic, or robotic approach. Worldwide pioneers for each technique are invited as authors and portray in step-by-step detail about each procedure. Of the 32 chapters, 23 are dedicated only for the surgical procedures. Each chapter is enriched by numerous figures, which complement the text, permitting the understanding of each surgical technique from its beginning until the last step. Eight additional chapters are dedicated to the clinical and anatomical aspects of rectal cancer. In the last decade there has been an impressive evolution in the treatment of patients with rectal cancer, with a focus not only on the preservation of a cancer-free life, but the quality of that life. This book has been written to be useful for everyone involved in rectal cancer management. From internists, gastroenterologists, endoscopists, oncologists, radiotherapists and radiologists involved in the treatment of rectal cancer during their daily practice, to surgeons specialized in colorectal surgery, to junior faculty to trainees, all interested in new and innovative techniques.

Download or read book The Health Professional s Guide to Gastrointestinal Nutrition written by Laura E. Matarese and published by Eat Right. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This one-stop, comprehensive reference guide is written by prominent physicians and RDNs in GI nutrition. Topics include tests and procedures; nutrition assessment; GI tract disorders; liver and exocrine disorders; gastrointestinal surgery and oncology; and a variety of therapeutic interventions, including enteral and parenteral nutrition, probiotics and nutraceuticals.

Download or read book Product Lifecycle Management in the Digital Twin Era written by Clement Fortin and published by Springer Nature. This book was released on 2020-02-28 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed post-conference proceedings of the 16th IFIP WG 5.1 International Conference on Product Lifecycle Management, PLM 2019, held in Moscow, Russia, in July 2019. The 38 revised full papers presented were carefully reviewed and selected from 63 submissions. The papers are organized in the following topical sections: 3D modelling and data structures; PLM maturity and industry 4.0; ontologies and semantics; PLM and conceptual design; knowledge and change management; IoT and PLM; integrating manufacturing realities; and integration of in-service and operation.

Download or read book Ending Medical Reversal written by Vinayak K. Prasad and published by JHU Press. This book was released on 2015-11 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medications such as Vioxx and procedures such as vertebroplasty for back pain are among the medical "advances" that turned out to be dangerous or useless. What Dr. Vinayak K. Prasad and Dr. Adam S. Cifu call medical reversal happens when doctors start using a medication, procedure, or diagnostic tool without a robust evidence base—and then stop using it when it is found not to help, or even to harm, patients. In Ending Medical Reversal, Drs. Prasad and Cifu narrate fascinating stories from every corner of medicine to explore why medical reversals occur, how they are harmful, and what can be done to avoid them. They explore the difference between medical innovations that improve care and those that only appear to be promising. They also outline a comprehensive plan to reform medical education, research funding and protocols, and the process for approving new drugs that will ensure that more of what gets done in doctors' offices and hospitals is truly effective. "Every doctor should read this book."—JAMA Internal Medicine "[A]n excellent and realistic discussion of some of the horror stories that occur in medical practice . . . Highly recommended."—Choice "Ending Medical Reversal goes far in teaching medical students and practicing physicians alike how to learn on our own."—The Lancet "This has to be on the reading list for medical and nursing students."—Nursing Times "Ending Medical Reversal presents persuasive evidence that many current standard-of-care treatments are probably ineffective or harmful, thoroughly explains how such treatments came to be accepted, and proposes a number of ways to address the general problem (only some of which involve avaricious companies and mercenary physicians) and minimize its impact on a specific patient."—Journal of Clinical Research Best Practices "Dr. Prasad and Dr. Cifu offer a five-step plan, including pointers for determining if a given treatment is really able to do what you want it to do, and advice on finding a like-minded doctor who won't object to a certain amount of back-seat driving."—The New York Times "When I describe Ending Medical Reversal as revolutionary, I don't use the term lightly. Go out and read it—right now."—Common Sense Family Doctor "Should be considered for undergraduate reading lists. Keep a copy in the pharmacy or your briefcase as a great icebreaker or discussion point with other local healthcare professionals."—The Pharmaceutical Journal

Download or read book Advanced 3D Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering written by Lisa C. du Toit and published by Elsevier. This book was released on 2020-03-08 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering explores the intricacies of nanostructures and 3D printed systems in terms of their design as drug delivery or tissue engineering devices, their further evaluations and diverse applications. The book highlights the most recent advances in both nanosystems and 3D-printed systems for both drug delivery and tissue engineering applications. It discusses the convergence of biofabrication with nanotechnology, constructing a directional customizable biomaterial arrangement for promoting tissue regeneration, combined with the potential for controlled bioactive delivery. These discussions provide a new viewpoint for both biomaterials scientists and pharmaceutical scientists. - Shows how nanotechnology and 3D printing are being used to create systems which are intelligent, biomimetic and customizable to the patient - Explores the current generation of nanostructured 3D printed medical devices - Assesses the major challenges of using 3D printed nanosystems for the manufacture of new pharmaceuticals

Download or read book Fiber Fueled written by Will Bulsiewicz, MD and published by Penguin. This book was released on 2020-05-12 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The instant New York Times, USA Today, and Publisher's Weekly bestseller A bold new plant-based plan that challenges popular keto and paleo diets, from an award-winning gastroenterologist. The benefits of restrictive diets like paleo and keto have been touted for more than a decade, but as renowned gastroenterologist Dr. Will Bulsiewicz, or "Dr. B," illuminates in this groundbreaking book, the explosion of studies on the microbiome makes it abundantly clear that elimination diets are in fact hazardous to our health. What studies clearly now show--and what Dr. B preaches with his patients--is that gut health is the key to boosting our metabolism, balancing our hormones, and taming the inflammation that causes a host of diseases. And the scientifically proven way to fuel our guts is with dietary fiber from an abundant variety of colorful plants. Forget about the fiber your grandmother used to take--the cutting-edge science on fiber is incredibly exciting. As Dr. B explains, fiber energizes our gut microbes to create powerhouse postbiotics called short-chain fatty acids (SCFAs) that are essential to our health. SCFAs are scientifically proven to promote weight loss, repair leaky gut, strengthen the microbiome, optimize the immune system, reduce food sensitivities, lower cholesterol, reverse type 2 diabetes, improve brain function, and even prevent cancer. Restrictive fad diets starve the gut of the critical fiber we need, weaken the microbes, and make our system vulnerable. As a former junk-food junkie, Dr. B knows firsthand the power of fiber to dramatically transform our health. The good news is that our guts can be trained. Fiber-rich, real foods--with fruits, vegetables, whole grains, seeds, nuts, and legumes--start working quickly and maintain your long-term health, promote weight loss, and allow you to thrive and feel great from the inside out. With a 28-day jumpstart program with menus and more than 65 recipes, along with essential advice on food sensitivities, Fiber Fueled offers the blueprint to start turbocharging your gut for lifelong health today.

Download or read book Functional and Motility Disorders of the Gastrointestinal Tract written by Brian E. Lacy and published by Springer. This book was released on 2014-10-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the myriad of functional and motility gastrointestinal disorders in a comprehensive manner. The book is divided into seven major sections, with each section beginning with a brief case presentation highlighting the specific disorder to be reviewed. Appropriate criteria is highlighted, followed by a brief review on the epidemiology, etiology, pathophysiology, diagnosis and treatment of each specific disorder. 2-3 key teaching “pearls”, test questions and key references are also provided for each chapter. The book is organized so that each chapter can stand on its own and be used as a quick reference source in the clinic. Alternatively, it can be read cover to cover as an authoritative textbook on gastrointestinal functional and motility disorders. Written by international experts in the field of motility disorders, Functional and Motility Disorders of the Gastrointestinal Tract: A Case Study Approach is an invaluable resource for experienced physicians, students, residents, fellows, nurse practitioners and physician assistants.