Download or read book Perfusion Techniques in Biochemistry written by Brian David Ross and published by . This book was released on 1972 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Perfusion Techniques in Biochemistry written by B. D. Ross and published by . This book was released on 1972 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Principles and Techniques of Practical Biochemistry written by Keith Wilson and published by Cambridge University Press. This book was released on 2000-03-16 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition of biochemistry textbook which introduces principles and techniques used in undergraduate practical classes.
Download or read book Laboratory techniques in biochemistry and molecular biology written by and published by . This book was released on 1969 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Principles and Methods of Toxicology written by A. Wallace Hayes and published by CRC Press. This book was released on 2007-09-25 with total page 2296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanis
Download or read book Laboratory Techniques in Biochemistry and Molecular Biology written by Thomas Spence Work and published by . This book was released on 1969 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Oxford Textbook of Critical Care written by Webb and published by Oxford University Press. This book was released on 2020-01-10 with total page 1961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.
Download or read book Techniques in the Life Sciences written by and published by . This book was released on 1979 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biological Microtechnique written by Jeremy Sanderson and published by Garland Science. This book was released on 2020-08-13 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: A completely new practical guide to both new and classical methods of slide-making which is easy-to-read and easy-to-understand. Biological Microtechnique contains a wealth of practical detail which will provide a firm grounding in preparative methods for light microscopy.
Download or read book Integrated Strategies for Drug Discovery Using Mass Spectrometry written by Mike S. Lee and published by John Wiley & Sons. This book was released on 2005-09-02 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: New strategies and techniques for today's fast-paced discoveryprocess Today, the pressure is on for high-throughput approaches toaccelerate the generation, identification, and optimization ofmolecules with desirable drug properties. As traditional methods ofanalysis become antiquated, new analytical strategies andtechniques are necessary to meet sample throughput requirements andmanpower constraints. Among them, mass spectrometry has grown to bea front-line tool throughout drug discovery. Integrated Strategies for Drug Discovery Using Mass Spectrometryprovides a thorough review of current analytical approaches,industry practices, and strategies in drug discovery. The topicsrepresent current industry benchmarks in specific drug discoveryactivities that deal with proteomics, biomarker discovery,metabonomic approaches for toxicity screening, lead identification,compound libraries, quantitative bioanalytical support,biotransformation, reactive metabolite characterization, leadoptimization, pharmaceutical property profiling, sample preparationstrategies, and automation. THIS BOOK: * Clearly explains how drug discovery and mass spectrometry areinterconnected * Discusses the uses and limitations of various types of massspectrometry in various aspects of drug discovery * Prominently features analytical applications that requiretrace-mixture analysis * Provides industry applications and real-world examples * Shares historical background information on various techniques toaid in the understanding of how and why new methods are now beingemployed to analyze samples
Download or read book Visualizing Chemistry written by National Research Council and published by National Academies Press. This book was released on 2006-06-01 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists and engineers have long relied on the power of imaging techniques to help see objects invisible to the naked eye, and thus, to advance scientific knowledge. These experts are constantly pushing the limits of technology in pursuit of chemical imagingâ€"the ability to visualize molecular structures and chemical composition in time and space as actual events unfoldâ€"from the smallest dimension of a biological system to the widest expanse of a distant galaxy. Chemical imaging has a variety of applications for almost every facet of our daily lives, ranging from medical diagnosis and treatment to the study and design of material properties in new products. In addition to highlighting advances in chemical imaging that could have the greatest impact on critical problems in science and technology, Visualizing Chemistry reviews the current state of chemical imaging technology, identifies promising future developments and their applications, and suggests a research and educational agenda to enable breakthrough improvements.
Download or read book Drug Discovery and Evaluation written by Hans G. Vogel and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, including tests for cardiovascular, analgesic, psychotropic, metabolic, endocrine, respiratory, renal, and immunomodulatory activities. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a description of the experimental procedure, a critical assessment of the results and their pharmacological and clinical relevance, and pertinent references. Identification of specific tests is facilitated by the enclosed CD-ROM which allows for a quick and full text research. An appendix with guidelines and legal regulations for animal experiments in various countries will help to plan these experiments properly in accordance with the welfare of laboratory animals.
Download or read book Handbook of Mutagenicity Test Procedures written by B.J. Kilbey and published by Elsevier. This book was released on 2012-12-02 with total page 876 pages. Available in PDF, EPUB and Kindle. Book excerpt: The compilation of this book was prompted by the necessity of a bench volume which could provide the necessary background information on materials, experimental design, pitfalls and dificulties, in order to perform a particular test in an acceptable way with a minimal need for additional expert help. This Second Edition updates this information, providing: - a comprehensive bench guide - methods known to be reliable - a broad spectrum of approaches - tips to avoid pitfalls when using unfamiliar techniques - data from population records - safety aspects of mutagens and carcinogens - basic statistical concepts for experiment design This `on the bench' methodological text provides the necessary information for most of the common assays for genetic damage in use. The book includes methods which have been sufficiently used and tested to make their use reliable, but also presents methods which are not widely used at present, but which might prove most useful in screening for mutagenic effects.
Download or read book Advances in Steroid Biochemistry and Pharmacology written by M. H. Briggs and published by Elsevier. This book was released on 2014-06-28 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Steroid Biochemistry and Pharmacology, Volume 4 provides information pertinent to the fundamental aspects of steroid biochemistry and pharmacology. This book covers a variety of topics, including cellular biochemistry, pituitary hormones, corticosteroids, and steroid hormones. Organized into seven chapters, this volume begins with an overview of the potential effects of steroids on cellular biochemistry. This text then examines the development of sleep-monitoring methods, together with methods of plasma sampling that enable very frequent specimen to be taken without disturbing the subject. Other chapters consider the usefulness of sleep-related growth hormone release in diagnosis in both children and adult. This book discusses as well the versatile effect of corticosteroids on the cellular components of the connective tissue. The final chapter deals with the functioning of the adrenal cortex and its control by adrenocorticotropic hormone (ACTH). This book is a valuable resource for biochemists, histochemists, biologists, pharmacologists, clinicians, and experimental endocrinologists.
Download or read book CRC Handbook of Laboratory Model Systems for Microbial Ecosystems written by Julian W.T. Wimpenny and published by CRC Press. This book was released on 1988-10-31 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: These volumes present the main classes of useful laboratory model systems used to study microbial ecosystems, with emphasis on the practical details for the use of each model. The most commonly used model, the homogeneous fermenter, is featured along with linked homogeneous culture systems, film fermenters, and percolating columns. Additionally, gel-stabilized culture systems which incorporate molecular diffusion as their main solute transfer mechanism and the microbial colony are explained. Chapters comparing model systems with "microcosms" are included, along with discussions of the value of computer models in microbial ecosystem research. Highlighted is a global discussion of the value of laboratory models in microbial ecology.
Download or read book Pharmacology of Intestinal Permeation I written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 719 pages. Available in PDF, EPUB and Kindle. Book excerpt: The intestine, particularly the small bowel, represents a large surface (in the adult 2 human approximately 200m ) through which the body is exposed to its environment. A vigorous substrate exchange takes place across this large surface: nutrients and xenobiotics are absorbed from the lumen into the bloodstream or the lymph, and simultaneously, the same types of substrate pass back into the lumen. The luminal surface of the intestine is lined with a "leaky" epithelium, thus the passage of the substrates, in either direction, proceeds via both transcellular and intercellular routes. Simple and carrier-mediated diffusion, active transport, pinocytosis, phagocytosis and persorption are all involved in this passage across the intestinal wall. The term "intestinal permeation" refers to the process of passage of various substances across the gut wall, either from the lumen into the blood or lymph, or in the opposite direction. "Permeability" is the condition of the gut which governs the rate of this complex two-way passage. The pharmacologist's interest in the problem of intestinal permeation is twofold: on the one hand, this process determines thebioavailability of drugs and contributes significantly to the pharmacokinetics and toxicokinetics of xeno biotics; on the other hand, the pharmacodynamic effects of many drugs are manifested in a significant alteration of the physiological process of intestinal permeation.
Download or read book Advances in Physiology Biochemistry and Function V4 written by A.D. Johnson and published by Elsevier. This book was released on 2012-12-02 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Testis: Advances in Physiology, Biochemistry, and Function, Volume IV, provides an overview of the state of knowledge in the physiology, biochemistry, and function of the testis. This volume updates those areas of greatest research activity and introduces in a more complete manner those topics which have developed as subject areas in themselves. It includes a chapter on testicular steroidogenesis, which updates and expands the chapter appearing in Volume II. In addition, chapters on the role of FSH in the testis, the specialized (largely endocrine) functions of the Sertoli cells, and the entire account of the tubular hormone inhibin have all been extensions of material in the original chapter on testicular endocrinology. Similarly, separate chapters on blood flow in the testis, fluid secretion, and the blood-testis barrier all report data on subjects largely unsuspected when Volumes I-III were published. Neither the first three volumes nor is the present one intended primarily for the nonprofessional biologist or the popular reader. The coverage should be most useful and informative to professional biologists. It is anticipated that this volume will also be of interest to advanced students of animal biology as an authoritative, comprehensive, and convenient review of significant recent information concerning the testis.
