Download or read book Biomolecular Patterning on Micro and Nanofabricated Surfaces for Biosensor Applications and Cell based Research written by Reid Nelson Orth and published by . This book was released on 2003 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this study, biomaterials are patterned at the micro- and nanometer scale for biosensor applications and cell-based research. Two enabling technologies were photoactivatable biotin and the polymer lift-off technique. Avidin-biotin complexes have been immobilized on planar silicon substrates and to the inner surfaces of capillary tubes. The latter serves as a model for patterning inside microfluidic systems. Several biomaterials have been patterned using the polymer lift-off method, including lipids, metal, microspheres, biotin, and proteins (e.g., antibodies, protein A, and NeutrAvidin). The patterned lipids formed supported lipid bilayers with diffusion coefficients comparable to cell membranes as confirmed by fluorescence recovery after photobleaching (FRP). The author's tailored patterns comprised 2, 4-dinitrophenyl (DNP) or biotin functionalized lipids with features ranging from 1.3 micrometers to 76 micrometers. Non-lipid molecules were patterned in features as small as 700 nanometers. A characterization of the surfaces has shown a highly uniform patterning. Several of these materials also were applied in patterned regions inside microtrenches. Micro- and nanometer-scale patterns of functionalized biomaterials served as spatially controlled stimuli for cell surface ligands in this research. This technology has been applied to rat basophilic leukocyte (RBL) cells, eosinophils, lymphocytes, macrophages, and fibroblasts. For RBL experiments, DNP-conjugated lipids have been incorporated in the lipid bilayers with fluorescent lipid DiIC16 and used to stimulate RBL cells sensitized with anti-DNP IgE on the Fc receptors. Receptor aggregation was observed with confocal microscopy. This technique allows researchers to study the effects of antigen density on cellular response, binding kinetics, and the redistribution after individual binding events. (1 table, 71 figures).
Download or read book Electroanalytical Methods Of Biological Materials written by Anna Brajter-toth and published by CRC Press. This book was released on 2002-03-21 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text details contemporary electroanalytical strategies of biomolecules and electrical phenomena in biological systems. It presents developments in sequence-specific DNA detection for more efficient medical diagnosis of genetic and infectious diseases and microbial and viral pathogens.
Download or read book Biomolecular Patterning in Microfabricated Systems with Avidin biotin and Microcontact Printing written by Reid Nelson Orth and published by . This book was released on 2001 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Environmental Chemical and Medical Sensors written by Shantanu Bhattacharya and published by Springer. This book was released on 2017-12-22 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the fundamentals of sensor technologies as well as the recent research for the development of environmental, chemical and medical sensor technologies. Chapters include current research on microflow cytometry, microfluidic devices, colorimetric sensors, and the development of low-cost optical densitometric sensors and paper based analytical devices for environmental and biomedical applications. Special focus has been given to nanotechnology and nanostructures- their fabrication, uses and utility in different fields of research such as for the design of tools for medical diagnostics, therapeutics, as well as for detection and estimation of pollutant levels in water and air quality monitoring. This book is intended as a resource for researchers working in the field of sensor development across the world.
Download or read book Unconventional Nanopatterning Techniques and Applications written by John A. Rogers and published by John Wiley & Sons. This book was released on 2008-11-13 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patterning or lithography is at the core of modern science and technology and cuts across all disciplines. With the emergence of nanotechnology, conventional methods based on electron beam lithography and extreme ultraviolet photolithography have become prohibitively expensive. As a result, a number of simple and unconventional methods have been introduced, beginning first with research demonstrations in the mid 1990s. This book focuses on these unconventional patterning techniques and their applications to optics, organic devices, electronic devices, biological devices, and fluidics.
Download or read book Applications in Industry written by and published by Elsevier. This book was released on 1998-12-17 with total page 1091 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume I contains a brief review of adsorption history and its development for practical purposes up until now. It also presents some important information on adsorbents and catalysts as well as on the methods of their characterization. The part of this volume dealing with practical industrial applications includes chapters presenting advanced technical tools for high capacity adsorption separation of liquid and gas mixtures, development of new adsorbents for removal of hazardous contaminants from combustion flue gases and wastewaters, degasification of coal seams and fabrication of inorganic membranes and their applications. A comprehensive review is also included on contemporary utility of self-assembled monolayers, adsorption proteins and their role in modern industry, adsorption methods in technology of optical fibre glasses, sol-gel technology, solid desiccant dehumidification systems, etc. The articles give both the scientific backgrounds of the phenomena discussed and emphasize their practical aspects.The chapters give not only brief current knowledge about the studied problems, but are also a source of topical literature on the subject. A comprehensive bibliography on adsorption principles, design data and adsorbent materials for industrial applications for the period 1967-1997 concludes the book.
Download or read book Biosensors written by Pier Andrea Serra and published by BoD – Books on Demand. This book was released on 2011-07-18 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biosensor is a detecting device that combines a transducer with a biologically sensitive and selective component. Biosensors can measure compounds present in the environment, chemical processes, food and human body at low cost if compared with traditional analytical techniques. This book covers a wide range of aspects and issues related to biosensor technology, bringing together researchers from 19 different countries. The book consists of 27 chapters written by 106 authors and divided in three sections: Biosensors Technology and Materials, Biosensors for Health and Biosensors for Environment and Biosecurity.
Download or read book Biomedical Applications of Micro and Nanoengineering written by and published by . This book was released on 2006 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Nanosensors written by Gomaa A. M. Ali and published by Springer Nature. This book was released on with total page 1769 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Recent Global Research and Education Technological Challenges written by Ryszard Jabłoński and published by Springer. This book was released on 2016-09-22 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developments in the connected fields of solid state physics, bioengineering, mechatronics and nanometrology have had a profound effect on the emergence of modern technologies and their influence on our lives. In all of these fields, understanding and improving the basic underlying materials is of crucial importance for the development of systems and applications. The International Conference Inter-Academia 2016 has successfully married these fields and become a regular feature in the conference calendar. It consisted of seven thematic areas in the field of material science, nanotechnology, biotechnology, plasma physics, metrology, robotics, sensors and devices. The book Recent Global Research and Education: Technological Challenges is intended for use in academic, government and industry R&D departments, as an indispensable reference tool for the years to come. Also, we hope that the volume can serve the world community as the definitive reference source in Advances in Intelligent Systems and Computing. This book comprises carefully selected 68 contributions presented at the 15th International Conference on Global Research and Education INTER-ACADEMIA 2016, organized by Faculty of Mechatronics, Warsaw University of Technology, on September 26-28, in Warsaw, Poland. It is the second volume in series, following the edition in 2015. It brings together the knowledge and experience of 150 leading researchers representing 13 countries. We would like to thank all contributors and reviewers for helping us to put-together this book.
Download or read book Medical Biosensors for Point of Care POC Applications written by Roger Narayan and published by Woodhead Publishing. This book was released on 2016-08-21 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Biosensors for Point of Care (POC) Applications discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care. Part 1 covers the fundamentals of medical biosensors for point-of-care applications. Chapters in part 2 go on to look at materials and fabrication of medical biosensors while the next part looks at different technologies and operational techniques. The final set of chapters provide an overview of the current applications of this technology. Traditionally medical diagnostics have been dependent on sophisticated technologies which only trained professionals were able to operate. Recent research has focused on creating point-of-care diagnostic tools. These biosensors are miniaturised, portable, and are designed to be used at the point-of-care by untrained individuals, providing real-time and remote health monitoring. - Provides essential knowledge for designers and manufacturers of biosensors for point-of-care applications - Provides comprehensive coverage of the fundamentals, materials, technologies, and applications of medical biosensors for point-of-care applications - Includes contributions from leading international researchers with extensive experience in developing medical biosensors - Discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care
Download or read book Nanobiotechnology written by Christof M. Niemeyer and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is the key technology of the 21st century. The possibility to exploit the structures and processes of biomolecules for novel functional materials, biosensors, bioelectronics and medical applications has created the rapidly growing field of nanobiotechnology. Designed as a broad survey of the field, this book combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science and bioanalytics to fathom the full scope of current and future developments. It is divided into four main sections: * Interphase Systems * Protein-based Nanostructures * DNA-based Nanostructures * Nanoanalytics Each chapter describes in detail currently available methods and contains numerous references to the primary literature, making this the perfect "field guide" for chemists, biologists and materials scientists who want to explore the fascinating world of nanobiotechnology.
Download or read book Comprehensive Biomaterials II written by Kevin Healy and published by Elsevier. This book was released on 2017-05-18 with total page 4865 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications
Download or read book Advanced Materials and Techniques for Biosensors and Bioanalytical Applications written by Pranab Goswami and published by CRC Press. This book was released on 2020-11-01 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioanalytical science and its technological subdomain, biosensors, are ever-evolving subjects, striving for rapid improvement in terms of performance and expanding the target range to meet the vast societal and market demands. The key performance factors for a biosensor that drive the research are selectivity, sensitivity, response time, accuracy, and reproducibility, with additional requirements of its portability and inexpensive nature. These performance factors are largely governed by the materials and techniques being used in these bioanalytical platforms. The selection of materials to meet these requirements is critical, as their interaction or involvement with the biological recognition elements should initiate or improve these performance factors. The technique discussed primarily applies to transducers involved in converting a biochemical signal to optical or electrical signals. Over the years, the emergence of novel materials and techniques has drastically improved the performance of these bioanalytical systems, enabling them to expand their analytical horizon. These advanced materials and techniques are central to modern bioanalytical and biosensor research. Advanced Materials and Techniques for Biosensors and Bioanalytical Applications provides a comprehensive review of the subject, including a knowledge platform for both academics and researchers. Considering biosensors as a central theme to this book, an outline on this subject with background principles has been included, with a scope of extending the utility of the book to coursework in graduate and postgraduate schools. Features: • Basic principles on different classes of biosensors, recent advances and applications • Smart materials for biosensors and other rapid, portable detection devices • Metal nanoparticles and nanocrystals for analytical applications • Carbon-based nanoparticles and quantum dots for sensing applications • Nanozymes as potential catalysts for sensing applications • Bioelectrochemiluminescence and photoelectrochemical-based biosensors • Paper electronics and paper-based biosensors • Microbial biosensors: artificial intelligence, genetic engineering, and synthetic biology • Biofuel cells as a signal transduction platform • FET-based biosensors, including ISFET and BioFET This book serves as a reference for scientific investigators and a textbook for a graduate-level course in biosensors and advanced bioanalytical techniques.
Download or read book Poly Ethylene Terephthalate Based Blends Composites and Nanocomposites written by P.M. Visakh and published by William Andrew. This book was released on 2015-08-24 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poly(Ethylene Terephthalate) (PET) is an industrially important material which is not treated specifically in any other book. Poly(Ethylene Terephthalate) Based Blends, Composites and Nanocomposites fills this gap and systematically guides the reader through all aspects of PET and its blends, composites and nanocomposites. It covers theoretical fundamentals, nanocomposites preparation, modification techniques, structure-property relationships, characterisation of the different blends and composites, and material choice for specific applications. Consisting of contributions from experts in the field this book is a useful reference for the researchers and engineers working on the development and characterization of PET materials as well as on implementing them in real-world products. It can also be used as a standard reference for deeper insight in the mechanical, thermal, thermo-mechanical and visco-elastic aspects in product design decisions. - Provides a systematic overview on all types of poly(ethylene) terephthalate (PET) based blends, composites and nanocomposites - Informs about characterization, structure-property relationships and types of modifications - Links material properties to specific applications, enabling engineers to make the best material choice to increase product performance and cost efficiency, in industries ranging from aerospace to energy
Download or read book Biosensors and Cancer written by Victor R. Preedy and published by CRC Press. This book was released on 2012-07-27 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the importance and application of biosensors is complicated by the diverse range of methods and applications. Furthermore, existing texts are somewhat technical in nature, making it difficult for the novice. This book disseminates information on biosensors in a readable way, suitable to a wide audience with varying levels of experience. Topics include optical imaging, surface plasmon resonance, microcantilevers, electrochemistry, aptamers, fluorescence, electrochemistry, nanobiosensors, and nanowires.
Download or read book Functional Nanostructured Membranes written by Enrico Drioli and published by CRC Press. This book was released on 2018-12-07 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: A membrane is considered the heart of every separation process because it is developed as a nanostructured/nanofunctionalized thin barrier that controls the exchange between two phases, not only by external forces and under the effect of fluid properties, but also through the intrinsic characteristics of the membrane material itself. This book compiles cutting-edge research in membrane science, nanomaterials, and nanotechnologies, mainly from interdisciplinary research groups at the Institute on Membrane Technology, National Research Council (ITM-CNR), Italy, working on membrane design, membrane process engineering, and selected materials and practices for enhanced transport mass, charge, and energy. It covers topics on the design of new nanostructured membranes with improved properties, together with the identification of efficient transport–property relationships. It shares and strengthens the knowledge of making membrane technology a much more powerful and eco-friendly route, enabling one to provide prospective solutions and benefits for numerous fields of applications where traditional separation technologies suffer from many deficiencies. It is a great reference for researchers and investigators; graduate, PhD, and postgraduate students; and end users interested in membrane science and technology, nanomaterials, eco-friendly separation, chemistry, biology, and process engineering.
