Download or read book Pathways of progression written by Field, Simon and published by UNESCO Publishing. This book was released on 2018-11-12 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tumor Microenvironment Molecular Mechanisms and Signaling Pathways Involved in Metastatic Progression written by Antonella Zannetti and published by Frontiers Media SA. This book was released on 2021-09-30 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inflammatory Tumor Immune Microenvironment Molecular Mechanisms and Signaling Pathways in Cancer Progression and Metastasis written by Xu Wang and published by Frontiers Media SA. This book was released on 2022-03-25 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pathways to the Common Core written by Lucy Calkins and published by Heinemann Educational Books. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lucy Calkins and her colleagues at the Reading and Writing Project have helped thousands of educators design their own pathways to the Common Core. Now, with Pathways to the Common Core, they are ready to help you find your way. Designed for teachers, school leaders, and professional learning communities looking to navigate the gap between their current literacy practices and the ideals of the Common Core, Pathways to the Common Core will help you: understand what the standards say, suggest, and what they don't say; recognize the guiding principles that underpin the reading and writing standards; identify how the Common Core's infrastructure supports a spiraling K-12 literacy curriculum; and scrutinize the context in which the CCSS were written and are being unrolled. In addition to offering an analytical study of the standards, this guide will also help you and your colleagues implement the standards in ways that lift the level of teaching and learning throughout your school.--
Download or read book Pathway to Progression written by Khiry Jones and published by . This book was released on 2019-08-21 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A book that will help you find clarity in the midst of distraction and confusion
Download or read book Tumor Progression and Metastasis written by and published by BoD – Books on Demand. This book was released on 2020-04-08 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers significant coverage on different aspects of cancer from risk factors to the mechanisms leading to tumor progression and metastasis. Although tremendous progress has been made in cancer research and treatment, cancer metastasis remains a major unmet clinical need. The life and death of many cancer patients hangs on the degree of metastasis. This book provides new perspectives for diagnosis and cancer therapy. It includes new technologies and a new basis for current cancer therapies. To guarantee the high quality of this book, important topics are included and rigorously discussed in a simple and authentic way. The book addresses important challenges governing tumor progression and metastasis and brings new responses to both diagnosis and therapy. This book is a great source of knowledge and will be useful for researchers, medical doctors, oncologists, graduate and medical students, continued medical educators, health care providers, and all individuals interested in understanding cancer and its challenges.
Download or read book Pathways and Crime Prevention written by Alan France and published by Routledge. This book was released on 2013-06-17 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deals with the development of prevention policies and approaches that involve intervention 'early' in the lives of children, young people and their families. This book explores evidence that has been emerging from longitudinal and developmental prevention research.
Download or read book Noncoding RNA in Disease Diagnosis Etiology Progression Prognosis and Treatment written by Sujit Nair and published by Frontiers Media SA. This book was released on 2024-01-10 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exciting class of regulatory small noncoding RNAs (ncRNAs) has emerged in recent years that play key role(s) in the etiology/pathogenesis and diagnosis/prognosis of various human diseases including various hematologic and solid cancers, cardiovascular diseases including stroke/atherosclerosis, diabetes, obesity, and metabolic disorders, neuropathies, neurodegeneration including Alzheimer’s Disease, Parkinson’s Disease or Multiple Sclerosis, neurological disorders including epilepsy and muscular dystrophies, liver diseases, pulmonary fibrosis, immune-mediated inflammatory disorders and inflammatory bowel disease, gastritis, autoimmune disorders including arthritis, acromegaly, chronic kidney disease, allergic rhinitis, vitiligo, osteoporosis, obstructive sleep apnea, ocular disease, periodontitis, skeletal muscle atrophy, and parasitic diseases including leishmaniasis, amongst others. These ncRNAs include primarily microRNAs (miRNAs), long noncoding RNAs (lncRNAs), circular RNAs (circRNAs), piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), small interfering RNAs (siRNAs) or exosomal RNAs (exRNAs), etc. that modulate the expression of target genes thus potentially regulating protein expression in normal versus diseased individuals. This Research Topic recognizes the importance of and seeks to explore, ncRNAs in the diagnosis, etiology, progression, prognosis, and treatment of human disease as well as novel biomarker discovery by multi-omics technologies and other methodologies. Indeed, high-throughput technologies employing deep sequencing, proteogenomic, microarrays, and quantitative real-time PCR have begun to shed new light on the architecture of ncRNA landscapes in various diseases and key signal transduction cascades modulated by these ncRNAs in disease pathology. Epigenetic control of gene expression mediated via miRNAs, for instance, has expanded our understanding of transcriptional and post-transcriptional regulation of gene expression by critical ncRNAs in the cellular milieu. Network biology approaches including the construction of relevant ncRNA networks, ncRNA-mRNA networks, and bioinformatics for mining of ncRNAs, are gaining greater relevance in the search for ‘target hubs’ or novel biomarker(s) of disease. Delineation of ncRNA signatures by transcriptomic profiling or RNA-seq, for example, is an important milestone in furthering our knowledge of the repertoire of specific ncRNAs implicated in various diseases. Further, elucidation of the specific steps of the signaling cascades where ncRNAs exert their regulatory actions will augment our understanding of diseases. This will lead to the development of (i) a novel biomarker, or biomarker signature panel, for disease; (ii) ncRNA-based companion diagnostics for diagnosis of disease; (iii) point-of-care testing devices based on ncRNAs; (iv) newer therapeutic agents that target novel biomarkers with specificity, thereby reducing toxicity; (v) ncRNA-based prophylactic approaches of the future; and, (vi) ncRNA-based prognosis of disease.
Download or read book Mechanisms of Melanoma Tumor Progression written by Vladimir Spiegelman and published by Frontiers Media SA. This book was released on 2022-02-21 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Exploitation of Apoptosis Pathways in Prostate Cancer written by Natasha Kyprianou and published by World Scientific. This book was released on 2012 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the functional significance of targeting apoptosis for the treatment of prostate cancer. New concepts on the challenges relating to the development of resistance by androgen-independent tumors are introduced, in terms of the contribution of anoikis and cross-talk of androgens with key growth factor signaling pathways. This volume also provides insightful discussion on the exploitation of the apoptotic and angiogenic synergism towards complete eradication of prostate tumors. Last but not least, it includes reflections on the drug development challenge based on the analysis of data from existing clinical trials.
Download or read book Improving Healthcare Quality in Europe Characteristics Effectiveness and Implementation of Different Strategies written by OECD and published by OECD Publishing. This book was released on 2019-10-17 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, developed by the Observatory together with OECD, provides an overall conceptual framework for understanding and applying strategies aimed at improving quality of care. Crucially, it summarizes available evidence on different quality strategies and provides recommendations for their implementation. This book is intended to help policy-makers to understand concepts of quality and to support them to evaluate single strategies and combinations of strategies.
Download or read book Colorectal Cancer New Insights for the Healthcare Professional 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-10 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal Cancer: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Colorectal Cancer. The editors have built Colorectal Cancer: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Colorectal Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Colorectal Cancer: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book SPEC Contemporary Management of Metastatic Colorectal Cancer written by Aslam Ejaz and published by Academic Press. This book was released on 2022-06-23 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary Management of Metastatic Colorectal Cancer: A Precision Medicine Approach summarizes current knowledge and provides evidenced-based practice recommendations on how to treat patients with metastatic colorectal cancer. The book presents topics such as pre-operating imaging, the use of molecular markers in treatment decisions, neoadjuvant therapy, synchronous colorectal liver metastasis, and minimally invasive approaches. In addition, it discusses immunotherapy, targeted therapies and survivorship. This is a valuable resource for practitioners, cancer researchers, oncologists, graduate students and members of biomedical research who need to understand more about novel treatments for colorectal cancer metastasis. Summarizes contemporary data in the workup and treatment of patients with metastatic colorectal cancer Discusses novel patient-centric personalized approaches surrounding the management of such cancer types Presents evidenced-based recommendations for precision care among patients with metastatic colorectal cancer
Download or read book Forging Pathways to Improvise Music written by Joseph Montelione and published by Taylor & Francis. This book was released on 2023-08-22 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: A step-by-step resource on forging one’s own pathway to improvise music, this book guides the musician through a clear and simple method that will easily translate to the reader’s genre of choice. Many musicians struggle with improvisation. Coincidentally, educators also find it challenging to integrate improvisation into curriculum. This book breaks down the barriers most performers and educators combat in the learning and teaching of improvisation, and is a helpful approach to demystify the complicated sphere of music improvisation. Divided into three sections, the first part of the book helps the reader develop an improvisatorial mindset to mentally conceive musical ideas, regardless of genre. The second portion then connects the improviser’s mindset to translating those ideas into a compelling musical performance in real time. The book’s final third assists the reader with discovering how to apply this method of improvisation to the nuanced liturgical, comedic, jazz, and classical styles. Forging Pathways to Improvise Music offers a practical introduction to improvisational methods essential for educators, students, and musicians of diverse educational backgrounds and musical genres.
Download or read book Regulation of G1 Phase Progression written by Johannes Boonstra and published by Springer Science & Business Media. This book was released on 2003-09-30 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this contribution, several specialists describe the current knowledge on the molecular networks that regulate cell cycle progression, with an emphasis on the G1 phase of the cell cycle. The first part of Regulation of G1 Phase Progression is concerned with the individual molecules that form the network, including cyclins, cyclin-dependent kinases, inhibitors of these kinases and retinoblastoma and p53. The second section describes the signaling cascades by which external factors influence the cell cycle network, including mitogens, the extracellular matrix, nutrients and oxygen radicals. The last section describes the effects of specific external conditions on cell cycle progression and are presented such as serum starvation and subsequent re-addition and stress conditions (heat, osmolarity). The final two chapters describe the relation between cell cycle progression with cell differentiation and with apoptosis.
Download or read book Teaching Computing Unplugged in Primary Schools written by Helen Caldwell and published by Learning Matters. This book was released on 2016-10-18 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Teaching primary computing without computers? The Computing curriculum is a challenge for primary school teachers. The realities of primary school resources mean limited access to computer hardware. But computing is about more than computers. Important aspects of the fundamental principles and concepts of computer science can be taught without any hardware. Children can learn to analyse problems and computational terms and apply computational thinking to solve problems without turning on a computer. This book shows you how you can teach computing through ‘unplugged’ activities. It provides lesson examples and everyday activities to help teachers and pupils explore computing concepts in a concrete way, accelerating their understanding and grasp of key ideas such as abstraction, logic, algorithms and data representation. The unplugged approach is physical and collaborative, using kinaesthetic learning to help make computing concepts more meaningful and memorable. This book will help you to elevate your teaching, and your children's learning of computing beyond the available hardware. It focuses on the building blocks of understanding required for computation thinking.
Download or read book Progress in Medicinal Chemistry written by and published by Elsevier. This book was released on 2019-03-14 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Medicinal Chemistry, Volume 58, provides a review of eclectic developments in medicinal chemistry, with each chapter written by an international board of authors. Topics covered in this new release include Amyotrophic lateral sclerosis (ALS), Covalent-binding Drugs, Natural Product Drug Delivery – A Special Challenge?, and SMN2 gene splicing modifier, and more. Provides extended, timely reviews of topics in medicinal chemistry Contains targets and technologies relevant to the discovery of tomorrow’s drugs Presents analyses of successful drug discovery programs
