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Book Pathophysiology and Rational Pharmacotherapy of Myocardial Ischemia

Download or read book Pathophysiology and Rational Pharmacotherapy of Myocardial Ischemia written by G. Heusch and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ischemie heart disease is still the most frequent cause of death in the western world. There have been significant achievements in diagnostic procedures as well as in the medical, invasive, and surgiealtreatment ofischemieheart disease inrecent years. A variety ofdrugs are availablefor the pharmacotherapyofischemieheart disease, par ticularly nitrates, ß-blockers, and calcium-antagonists which are used as mono therapy or in various combinations. However, the selection of patients for a certain treatment, as weIl as the optimization of an individual treatment are still largely empirical. On the other hand, the recent advances in experimental cardiology emphasize the extremely complex and dynamie scenario of ischemic heart disease, involving endothelial damage, coagulation processes, metabolie and morphologie derangements, coronary constrictor mechanisms, blood flow redistribution, arrhythmogenesis, contraetile dysfunction during ischemia and reperfusion, and finally lack or presence of pain perception. Therefore, it appears desirable to close the gap between experimental and clinical cardiology and, thus, to provide a pathophysiologieal basis for rational cliniealdecisions with respect to diagnostic and therapeutic procedures. The idea for this book arose during the preparation of a seminar series on experi mental cardiology, when I found it diffieultto collect the pertinentinformation from textbooks of cardiology, physiology, pathology, and pharmacology, as well as from numerous review and original artieies on specifictopies. I am now very grateful that expert cliniealand experimental colleagues from around the world have joined me in the effort to provide a comprehensive textbook on the pathophysiology of myocar dial ischemia and its rational pharmacotherapy.

Book The Pathophysiology and Pharmacotherapy of Myocardial Infarction

Download or read book The Pathophysiology and Pharmacotherapy of Myocardial Infarction written by Nabil El-Sherif and published by Elsevier. This book was released on 2013-10-22 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pathophysiology and Pharmacotherapy of Myocardial Infarction deals with the advances in the pathophysiology and pharmacotherapy of acute myocardial infarction and related complications. This book covers two major consequences—cardiac muscle dysfunction and cardiac electrical dysfunction. This text begins by reviewing the controversy surrounding the pathogenetic mechanisms of atheroma formation and its potential reversibility, including the status of coronary risk factors and benefits of primary prevention. The pathophysiologic mechanisms of pump failure and the current approach to its management are then deliberated, followed by a discussion on the rational use of vasodilators in post-infarction heart failure and pharmacotherapy of cardiogenic shock. The rationale for the interest in the role of coronary vasospasm and thrombolytic therapy for acute myocardial infarction is also covered. This publication concludes by reviewing the approaches for the management of post-infarction ventricular tachyarrhythmias and concept of secondary prevention of sudden cardiac death. This compilation is valuable to medical students, primary care physicians, and cardiovascular specialists.

Book Introduction to Basics of Pharmacology and Toxicology

Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

Book Primary Angioplasty

    Book Details:
  • Author : Timothy J Watson
  • Publisher : Springer
  • Release : 2018-07-13
  • ISBN : 9811311145
  • Pages : 338 pages

Download or read book Primary Angioplasty written by Timothy J Watson and published by Springer. This book was released on 2018-07-13 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This quick-reference handbook offers a concise and practical review of key aspects of the treatment of ST-segment elevation myocardial infarction (STEMI) in the era of primary percutaneous coronary intervention (PPCI). In the context of STEMI, PPCI is the preferred mode of emergency revascularization. Access to PPCI is rapidly increasing and is now routinely practiced in both general and specialist hospitals and there has been a recent emphasis on developing STEMI networks to enhance and expedite the referral pathway. This coupled with concurrent developments to enhance the safety and efficacy of the PPCI procedure has heralded an era where STEMI interventions are increasingly considered an important subspecialty within interventional cardiology. Written by leading cardiologists who have been instrumental in the adoption of PPCI in their respective institutions, the book provides junior and senior cardiologists alike with insightful and thought-provoking tips and tricks to enhance the success of PPCI procedures, which may in turn translate into direct improvements in outcomes. The book is also relevant for healthcare providers and emergency department physicians.

Book Differential Diagnosis of Chest Pain

Download or read book Differential Diagnosis of Chest Pain written by Umashankar Lakshmanadoss and published by BoD – Books on Demand. This book was released on 2020-07-01 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide an excellent overview of the differential diagnosis and approach to chest pain in various clinical settings. This book is divided into two sections including the introduction and the approach to chest pain. Our introductory chapter starts with the basic principles of statistics and its application in various diagnostic modalities of heart disease. Our authors present a nice approach to patients presenting with chest pain in various scenarios. We have also included a chapter describing GERD, which could present as chest pain and another chapter describing aortic dissection, which is a life-threatening disease presenting with chest pain. We hope that this book will serve as an accessible handbook on the differential diagnosis of chest pain.

Book Translational Research in Coronary Artery Disease

Download or read book Translational Research in Coronary Artery Disease written by Wilbert S. Aronow and published by Academic Press. This book was released on 2015-10-29 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Research in Coronary Artery Disease: Pathophysiology to Treatment covers the entire spectrum of basic science, genetics, drug treatment, and interventions for coronary artery disease. With an emphasis on vascular biology, this reference fully explains the fundamental aspects of coronary artery disease pathophysiology. Included are important topics, including endothelial function, endothelial injury, and endothelial repair in various disease states, vascular smooth muscle function and its interaction with the endothelium, and the interrelationship between inflammatory biology and vascular function. By providing this synthesis of current research literature, this reference allows the cardiovascular scientist and practitioner to access everything they need from one source. Provides a concise summary of recent developments in coronary and vascular research, including previously unpublished data Summarizes in-depth discussions of the pathobiology and novel treatment strategies for coronary artery disease Provides access to an accompanying website that contains photos and videos of noninvasive diagnostic modalities for evaluation of coronary artery disease

Book Pathophysiology and Pharmacotherapy of Cardiovascular Disease

Download or read book Pathophysiology and Pharmacotherapy of Cardiovascular Disease written by Gowraganahalli Jagadeesh and published by Springer. This book was released on 2015-05-06 with total page 1323 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book covers the basic principles of cardiovascular physiology, pathophysiology and advanced pharmacology with particular emphasis on cellular mechanisms of drug action. It provides an update on the progress made in several aspects of cardiovascular diseases so that it might kindle scientists and clinicians alike in furthering basic and translational research. In addition, the book is expected to fill imperative gaps in understanding and optimally treating cardiovascular disease.

Book The ESC Textbook of Preventive Cardiology

Download or read book The ESC Textbook of Preventive Cardiology written by Stephan Gielen and published by European Society of Cardiology. This book was released on 2015 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: "EACPR, European Association for Cardiovascular Prevention and Rehabilitation -- European Society of Cardiology."

Book Cardioprotection

    Book Details:
  • Author : Derek Hausenloy
  • Publisher : Oxford University Press
  • Release : 2009-08-20
  • ISBN : 019954476X
  • Pages : 138 pages

Download or read book Cardioprotection written by Derek Hausenloy and published by Oxford University Press. This book was released on 2009-08-20 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary heart disease (CHD) is the leading cause of death worldwide. Cardioprotection refers to the prevention of CHD and the clinical improvement in patients suffering from cardiovascular problems.

Book Mechanical Complications of Myocardial Infarction

Download or read book Mechanical Complications of Myocardial Infarction written by Tirone E. David and published by . This book was released on 1993 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Pharmacological Treatment of Chronic Stable Angina Pectoris

Download or read book Pharmacological Treatment of Chronic Stable Angina Pectoris written by Pablo Avanzas and published by Springer. This book was released on 2015-06-02 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended for general cardiologists and other physicians involved in the care of patients with chronic stable angina (CSA). The goal of this book is to update clinicians on recent data on the medical management of patients with CSA. Ischemic heart disease remains a major public health problem. Chronic stable angina is the initial manifestation of ischemic heart disease in approximately one half of patients. Stable coronary artery disease is generally characterized by episodes of reversible myocardial demand/supply mismatch, related to ischaemia or hypoxia, which are usually inducible by exercise, emotion or other stress and reproducible—but, which may also be occurring spontaneously. Such episodes of ischaemia/hypoxia are commonly associated with transient chest discomfort (angina pectoris). The aim of the management of CSA is to reduce symptoms and improve prognosis. The management of these patients encompasses lifestyle modification, control of coronary artery disease risk factors, evidence-based pharmacological therapy and patient education. All patients with stable angina should be offered optimal medical treatment, defined as one or two anti-anginal drugs as necessary, plus drugs for secondary prevention of cardiovascular disease. Regarding the role of revascularization, randomised trials provide compelling evidence that myocardial revascularisation by coronary artery bypass grafting or by percutaneous coronary intervention improves symptoms of angina relative to continued medical treatment.

Book Thrombolytic Therapy in Acute Ischemic Stroke II

Download or read book Thrombolytic Therapy in Acute Ischemic Stroke II written by Gregory J. DelZoppo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, interest in treatment of ischemic stroke has increased significantly. Perhaps the single most important feature of attempts to improve the outcome of stroke patients has been that the interventions be applied within the very early hours of stroke symptoms. This has spawned efforts to understand the vascular and neuronal responses to cerebral artery reperfusion experimentally. Important prospective clinical studies of thrombolysis in acute ischemic stroke have been completed, and large placebo-controlled, symptom-based studies are now underway worldwide. Here, we consider the central features of those studies, their experimental basis, and the future importance of adjunctive therapies to recanalization in focal brain ischemia acutely. Risks and benefits are discussed. This collection benefits from the opinions of experts and workers in this rapidly evolving and exciting field.

Book Textbook of Stroke Medicine

    Book Details:
  • Author : Michael Brainin
  • Publisher : Cambridge University Press
  • Release : 2014-09-11
  • ISBN : 1107047498
  • Pages : 425 pages

Download or read book Textbook of Stroke Medicine written by Michael Brainin and published by Cambridge University Press. This book was released on 2014-09-11 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised throughout, the new edition of this concise textbook is aimed at doctors preparing to specialize in stroke care.

Book Clinical Guide to Cardiology

Download or read book Clinical Guide to Cardiology written by Christian Fielder Camm and published by John Wiley & Sons. This book was released on 2016-03-07 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Guide to Cardiology is a quick-reference resource, packed full of bullet points, diagrams, tables and algorithms for the key concepts and facts for important presentations and conditions within cardiology. It provides practical, evidence-based information on interventions, investigations, and the management of clinical cardiology. Key features include: A clear evidence-base providing key guidelines and clinical trials in each chapter Coverage of examination techniques, common conditions, imaging modalities (including ECGs, chest X-rays, MRI and CT), interventional therapies, and pharmacology A companion website at www.wiley.com/go/camm/cardiology featuring audio clips, developed for differing levels of knowledge, that explain key concepts or an area in greater detail, as well as numerous additional clinical case studies, audio scripts, and self-assessment material

Book Caplan s Stroke E Book

    Book Details:
  • Author : Louis Caplan
  • Publisher : Elsevier Health Sciences
  • Release : 2009-06-24
  • ISBN : 1437711162
  • Pages : 667 pages

Download or read book Caplan s Stroke E Book written by Louis Caplan and published by Elsevier Health Sciences. This book was released on 2009-06-24 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated and revised, this new edition of Caplan’s Stroke continues to provide a concise and pragmatic approach to the evaluation, diagnosis, and management of adult and pediatric stroke patients. Dr. Caplan—a highly esteemed stroke authority— shares with you his vast experience and wisdom as a stroke clinician, including his time-tested strategies and unique clinical pearls that you can implement into your own practice. Expanded coverage of imaging and laboratory diagnosis and treatment as well as extensive revisions throughout, brings you the latest advances on prevention, complications, and rehabilitation. The use of case studies illustrates the types of clinical scenarios you may experience in practice. And, its conversational, easy-to-read format make Caplan’s Stroke an ideal resource for general neurologists, non-neurologists, and stroke specialists alike. Discusses all cerebrovascular diseases to help you differentiate among all types of stroke so you can treat each patient appropriately. Takes a distinctly personal and individual approach to general principles, pathophysiology, diagnosis, treatment, and rehabilitation, offering practical, clinical guidance on stroke and stroke related issues. Provides detailed discussions on stroke syndromes in children and adults, including large artery occlusive disease of the anterior circulation, brain embolism, spinal cord stroke, and many, many more, to help you better manage every condition you see. Uses case studies to highlight and emphasize clinical points. Includes expanded coverage of imaging and laboratory diagnosis and treatment to help you make better informed evaluation and management decisions. Presents meticulous revisions and updates throughout, particularly to the chapters on stroke prevention and rehabilitation to keep you current on today’s best practices. Features a new two-color design with updated artwork and more images that elucidates key points and enhances visual guidance.

Book Coronary Microcirculation During Ischaemia and Reperfusion

Download or read book Coronary Microcirculation During Ischaemia and Reperfusion written by Stig Haunsø and published by Wiley-Blackwell. This book was released on 1997 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: