Download or read book Proton and Charged Particle Radiotherapy written by Thomas F. De Laney and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the first comprehensive and practical clinical reference on proton and charged particle radiotherapy. The first half of the book explains the treatment delivery systems used, offers detailed guidance on treatment planning techniques, examines key clinical issues in proton radiotherapy, and reviews recent experience with heavier charged particle radiotherapy. The second half of the book offers "how-to" information on treatment of pediatric tumors, lymphomas, and tumors of the central nervous system, eye, skull base, cervical spine, bone and soft tissue, paranasal sinus, nasal cavity, nasopharynx, oropharynx, oral cavity, salivary glands, prostate, lung, gastrointestinal tract, female reproductive tract, and breast. More than 100 full-color illustrations complement the text.
Download or read book Particle Therapy Technology for Safe Treatment written by Jay Flanz and published by CRC Press. This book was released on 2022-01-18 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: The path from clinical requirements to technical implementation is filtered by the translation of the modality to the technology. An important part of that filter is that the modality be safe. For that to be the case, it is imperative to understand what clinical parameters affect the safety of a treatment and then determine how the technology can affect those parameters. This book provides a practical introduction to particle therapy. It provides a thorough introduction to the technological tools and their applications and then details the components that are needed to implement them. It explains the foundations of beam production and beam delivery that serve to meet the necessary clinical requirements. It emphasizes the relationship between requirements and implementation, including how safety and quality are considered and implemented in the solution. The reader will learn to better understand what parameters are important to achieve these goals. Particle Therapy Technology for Safe Treatment will be a useful resource for professionals in the field of particle therapy in addition to biomedical engineers and practitioners in the field of beam physics. It can also be used as a textbook for graduate medical physics and beam physics courses. Key Features Presents a practical and accessible journey from application requirements to technical solutions Provides a pedagogic treatment of the underlying technology Describes how safety is to be considered in the application of this technology and how safety and quality can be factored into the overall system Author Bio After receiving his PhD in nuclear physics, Dr. Jacob Flanz was the Accelerator Physics Group leader and Principal Research Scientist at the Massachusetts Institute of Technology (MIT), USA, where he designed the recirculator and the GeV stretcher/storage ring. He joined Massachusetts General Hospital (MGH) and Harvard and became project and technical director of proton therapy, with responsibility for specifications, integration, and commissioning ensuring safe clinical performance. He invented the universal nozzle and led the design and implementation of beam scanning at MGH in 2008, including quality assurance. Dr. Flanz has been involved in several FDA applications for particle therapy. He developed and taught the US Particle Accelerator School course "Medical Applications of Accelerators and Beams." He was cochair of education and is currently the president of the Particle Therapy Co-Operative Group. Exercise solutions to accompany this book can be accessed via the 'Instructor Resources' tab on the book webpage.
Download or read book Particle Radiotherapy written by Arabinda Kumar Rath and published by Springer. This book was released on 2016-03-10 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: The results of decades of research and development are providing compelling evidence about the efficacy of radiation therapy with proton and carbon ion beams to achieve superior complication free tumor control leading to a world-wide rapid growth in their clinical use. This book contains comprehensive reviews of the state of the art of the technology and physics of heavy charge particle therapy by the experts from the leading cancer centers of world that will be valuable as a practical guide for radiation therapy professionals interested in these modalities.
Download or read book Principles and Practice of Particle Therapy written by Timothy D. Malouff and published by John Wiley & Sons. This book was released on 2022-06-13 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Practice of Particle Therapy Although radiation has been used therapeutically for over 100 years, the field of radiation oncology is currently in the midst of a renaissance, particularly with regards to the therapeutic use of particles. Over the past several years, access to particle therapy, whether it be proton therapy or other heavy ion therapy, has increased dramatically. Principles and Practice of Particle Therapy is a clinically oriented resource that can be referenced by both experienced clinicians and those who are just beginning their venture into particle therapy. Written by a team with significant experience in the field, topics covered include: Background information related to particle therapy, including the clinically relevant physics, radiobiological, and practical aspects of developing a particle therapy program “Niche” treatments, such as FLASH, BNCT, and GRID therapy The simulation process, target volume delineation, and unique treatment planning considerations for each disease site Less commonly used ions, such as fast neutrons or helium Principles and Practice of Particle Therapy is a go-to reference work for any health professional involved in the rapidly evolving field of particle therapy.
Download or read book Heavy Particle Radiotherapy written by M Raju and published by Elsevier. This book was released on 2012-12-02 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heavy Particle Radiotherapy covers the significant advances in the application of radiotherapy to cancer treatment. This book is composed of eight chapters that focus on the performance of several heavy particles. The introductory chapters describe the radiobiological phenomena of interest in radiotherapy and their modifications with increasing linear energy transfer. The remaining chapters discuss the physical aspects, cellular effects, and radiotherapy potential of heavy particles, including neutrons, protons, helium and heavy ions, and negative pions.
Download or read book Carbon Ion Radiotherapy written by Hirohiko Tsujii and published by Springer Science & Business Media. This book was released on 2013-12-25 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy.
Download or read book Proton Therapy Physics written by Harald Paganetti and published by CRC Press. This book was released on 2016-04-19 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization. Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution.
Download or read book Stereotactic Body Radiation Therapy written by Simon S. Lo and published by Springer Science & Business Media. This book was released on 2012-08-28 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.
Download or read book Advances in Particle Therapy written by Manjit Dosanjh and published by CRC Press. This book was released on 2018-05-11 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hadron therapy is a groundbreaking new method of treating cancer. Boasting greater precision than other therapies, this therapy is now utilised in many clinical settings and the field is growing. More than 50 medical facilities currently perform (or are planned to perform) this treatment, with this number set to double by 2020. This new text covers the most recent advances in hadron therapy, exploring the physics, technology, biology, diagnosis, clinical applications, and economics behind the therapy. Providing essential and up-to-date information on recent developments in the field, this book will be of interest to current and aspiring specialists from a wide range of backgrounds. Features: Multidisciplinary approach: explores the physics, IT (big data), biology, clinical applications from imaging to treatment, clinical trials, and economics associated with hadron therapy Contains the latest research and developments in this rapidly evolving field, and integrates them into the current global challenges for radiation therapy Edited by recognised leaders in the field, including the co-ordinator of ENLIGHT (the European Network for Light Ion Hadron Therapy), with chapter contributions from international leading experts in the field
Download or read book Proton and Carbon Ion Therapy written by C-M Charlie Ma and published by CRC Press. This book was released on 2012-10-09 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy. The text also offers detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. After an overview, the book focuses on the fundamental aspects of proton and carbon ion therapy equipment, including accelerators, gantries, and delivery systems. It then discusses dosimetry, biology, imaging, and treatment planning basics and provides clinical guidelines on the use of proton and carbon ion therapy for the treatment of specific cancers. Suitable for anyone involved with medical physics and radiation therapy, this book offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and the future outlook of proton and carbon ion therapy. It presents a thorough introduction for those new to the field while providing a helpful, up-to-date reference for readers already using the therapy in clinical settings.
Download or read book Proton and Carbon Ion Therapy written by C-M Charlie Ma and published by CRC Press. This book was released on 2012-10-09 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and trea
Download or read book Exploring the Potential of Particle Radiotherapy Helium Neutrons Carbon and Other Heavy Ions written by Timothy Dean Malouff and published by Frontiers Media SA. This book was released on 2021-09-27 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Target Volume Delineation and Treatment Planning for Particle Therapy written by Nancy Y. Lee and published by Springer. This book was released on 2017-12-19 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is designed to enable radiation oncologists to treat patients appropriately and confidently by means of particle therapy. The orientation and purpose are entirely practical, in that the focus is on the physics essentials of delivery and treatment planning , illustration of the clinical target volume (CTV) and associated treatment planning for each major malignancy when using particle therapy, proton therapy in particular. Disease-specific chapters provide guidelines and concise knowledge on CTV selection and delineation and identify aspects that require the exercise of caution during treatment planning. The treatment planning techniques unique to proton therapy for each disease site are clearly described, covering beam orientation, matching/patching field techniques, robustness planning, robustness plan evaluation, etc. The published data on the use of particle therapy for a given disease site are also concisely reported. In addition to fully meeting the needs of radiation oncologists, this "know why" and “know how” guide to particle therapy will be valuable for medical physicists, dosimetrists, and radiation therapists.
Download or read book Anterior Skull Base Tumors written by P. Nicolai and published by Karger Medical and Scientific Publishers. This book was released on 2020-07-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, interest in the management of anterior skull base tumors has been fostered by the introduction and subsequent rapid expansion of indications of transnasal endoscopic techniques. In parallel, extraordinary progress has been made in all the other disciplines which are involved in the complex process of managing anterior skull base tumors, leading to substantial improvements in diagnosis and treatment. The anterior skull base can be involved in a large variety of tumors of a varying nature and histology, which in the majority of cases originate from adjacent anatomic sites. In fact, primary lesions of the anterior skull base mainly include osteoma and other tumors originating from bone and cartilage. Tumors involving the anterior skull base have their origin prevalently in the sinonasal tract, but lesions developing on the intracranial site, such as meningiomas, may also extend caudally to encroach upon this area. All these lesions are rare, which means that the pertinent literature does not include prospective studies or treatment guidelines based on a high level of evidence. In view of the extreme histological variability of lesions involving the anterior skull base, much emphasis has been placed on addressing the different nuances of treatment in relation to histology, especially for malignant tumors. The chapters focusing on surgery provide divergent views on selection criteria for a specific surgical technique, which is the aim of this publication.
Download or read book Evaluation of Treatment Planning for Particle Beam Radiotherapy written by and published by . This book was released on 1987 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Charged Particles in Oncology written by Marco Durante and published by Frontiers Media SA. This book was released on 2018-01-31 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-energy charged particles represent a cutting-edge technique in radiation oncology. Protons and carbon ions are used in several centers all over the world for the treatment of different solid tumors. Typical indications are ocular malignancies, tumors of the base of the skull, hepatocellular carcinomas and various sarcomas. The physical characteristics of the charged particles (Bragg peak) allow sparing of much more normal tissues than it is possible using conventional X-rays, and for this reason all pediatric tumors are considered eligible for protontherapy. Ions heavier than protons also display special radiobiological characteristics, which make them effective against radioresistant and hypoxic tumors. On the other hand, protons and ions with high charge (Z) and energy (HZE particles) represent a major risk for human space exploration. The main late effect of radiation exposure is cancer induction, and at the moment the dose limits for astronauts are based on cancer mortality risk. The Mars Science Laboratory (MSL) measured the dose on the route to Mars and on the planet’s surface, suggesting that a human exploration missions will exceed the radiation risk limits. Notwithstanding many studies on carcinogenesis induced by protons and heavy ions, the risk uncertainty remains very high. In this research topic we aim at gathering the experiences and opinions of scientists dealing with high-energy charged particles either for cancer treatment or for space radiation protection. Clinical results with protons and heavy ions, as well as research in medical physics and pre-clinical radiobiology are reported. In addition, ground-based and spaceflight studies on the effects of space radiation are included in this book. Particularly relevant for space studies are the clinical results on normal tissue complications and second cancers. The eBook nicely demonstrates that particle therapy in oncology and protection of astronauts from space radiation share many common topics, and can learn from each other.
Download or read book Next Evolutions in Charged Particle Therapy written by Thomas Tessonnier and published by Frontiers Media SA. This book was released on 2022-08-03 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:
