Download or read book Parasite Neuromusculature and Its Utility as a Drug Target written by Aaron G. Maule and published by Cambridge University Press. This book was released on 2006-10-19 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nerve and muscle systems in helminth parasites interact in a highly co-ordinated manner to control movements associated with alimentation, reproduction, locomotion and attachment. All metazoan parasites rely on some or all of these activities for their survival. For a long time it has been known that neuromuscular function in parasites is susceptible to chemotherapeutic attack, and that compromising this aspect of parasite biology is sufficient to cure many parasite infections. This volume outlines the latest research in this area, showing why this system is so amenable to drug intervention and outlining potential targets for new treatments. Written by experts in the field, this volume will be invaluable to anyone interested in the molecular biology, physiology and biochemistry of parasites as well as those looking to exploit these for the creation of new treatments.
Download or read book Molecular Biochemistry and Physiology of Helminth Neuromuscular Systems written by David Halton and published by Cambridge University Press. This book was released on 1996 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of articles, edited by D. W. Halton, is the specially commissioned supplement to the journal Parasitology, volume 113.
Download or read book Chemotherapeutic Targets in Parasites written by Tag E. Mansour and published by Cambridge University Press. This book was released on 2002-11-04 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parasitic infections are the most prevalent of human diseases, and researchers continue to face the challenge of designing drugs to successfully counteract them. Chemotherapeutic Targets in Parasites analyzes the critical metabolic reactions and structural features essential for parasite survival, and advocates the latest molecular strategies with which to identify effective antiparasitic agents. An introduction to the early development of parasite chemotherapy is followed by an overview of biophysical techniques and genomic and proteomic analysis. Several chapters are devoted to specific types of chemotherapeutic agents and their targets in malaria, trypanosomes, leishmania and amitochondrial protists. Chapters on helminths include metabolic, neuromuscular, microtubular and tegumental targets. Emphasized throughout is the design of more selective and less toxic drugs than in the past. This book will be especially relevant to medical and clinical researchers and to graduate students in parasitology, pharmacology, medicine, microbiology, and biochemistry.
Download or read book Neuropeptide Systems as Targets for Parasite and Pest Control written by Timothy G. Geary and published by Springer Science & Business Media. This book was released on 2011-01-13 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need to continually discover new agents for the control or treatment of invertebrate pests and pathogens is undeniable. Agriculture, both animal and plant, succeeds only to the extent that arthropod and helminth consumers, vectors and pathogens can be kept at bay. Humans and their companion animals are also plagued by invertebrate parasites. The deployment of chemical agents for these purposes inevitably elicits the selection of resistant populations of the targets of control, necessitating a regular introduction of new kinds of molecules. Experience in other areas of chemotherapy has shown that a thorough understanding of the biology of disease is an essential platform upon which to build a discovery program. Unfortunately, investment of research resources into understanding the basic physiology of invertebrates as a strategy to illuminate new molecular targets for pesticide and parasiticide discovery has been scarce, and the pace of introduction of new molecules for these indications has been slowed as a result. An exciting and so far unexploited area to explore in this regard is invertebrate neuropeptide physiology. This book was assembled to focus attention on this promising field by compiling a comprehensive review of recent research on neuropeptides in arthropods and helminths, with contributions from many of the leading laboratories working on these systems.
Download or read book Parasitic Nematodes written by Malcolm W. Kennedy and published by CABI. This book was released on 2013 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering a wide range of rapidly-developing fields of research into parasitic nematodes, this comprehensive volume discusses the genetics, biochemistry and immunology of nematode parasites of humans as well as domestic animals and plants. This fully-updated edition also covers new advances including horizontal gene transfer, immune expulsion mechanisms, genetics of susceptibility in humans, nematode protein structures, role of bacterial symbionts, intrinsic immune response, host immune system modulation, modulation of allergic and autoimmune diseases and the use of parasitic nematodes or their products as therapeutics.
Download or read book Canine Parasites and Parasitic Diseases written by Seppo Saari and published by Academic Press. This book was released on 2018-11-07 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Canine Parasites and Parasitic Diseases offers a concise summary, including the distribution, epidemiology, lifecycle, morphology, clinical manifestations, diagnosis, prophylaxis and therapeutic measures on the most important parasites affecting dogs. The book includes their classification, structure, lifecycles, occurrence, and the diagnosis and treatment of infestations. Chapters are presented in a consistent and logical format with extensive use of tables, photographs and line drawings that help veterinarians and students quickly find answers to questions. The book informs on 100 different species of parasite related to the canine world and is is aimed not only at veterinary practitioners but also in dog enthusiasts, pharmacies and laboratories. Fully illustrated with high-quality figures and illustrations Provides insights on the risk factors and prevention of parasite infections in dogs and gives guidelines for anthelmintic treatment Serves professionals, students, parasitologists and veterinary scientists Present an easy-to-use handbook on the identification of canine parasites and the diseases associated with parasitic infection
Download or read book Medical Microbiology written by Patrick R. Murray, PhD and published by Elsevier Health Sciences. This book was released on 2015-10-28 with total page 977 pages. Available in PDF, EPUB and Kindle. Book excerpt: Turn to Medical Microbiology, 8th Edition for a thorough, clinically relevant understanding of microbes and their diseases. This succinct, easy-to-use text presents the fundamentals of microbiology and immunology in a clearly written, engaging manner-effectively preparing you for your courses, exams, and beyond. Coverage of basic principles, immunology, laboratory diagnosis, bacteriology, virology, mycology, and parasitology help you master the essentials. Review questions at the end of each chapter correlate basic science with clinical practice to help you understand the clinical relevance of the organisms examined. Clinical cases illustrate the epidemiology, diagnosis, and treatment of infectious diseases, reinforcing a clinical approach to learning. Full-color clinical photographs, images, and illustrations help you visualize the clinical presentations of infections. Summary tables and text boxes emphasizing essential concepts and learning issues optimize exam review. Additional images, 200 self-assessment questions, NEW animations, and more. Student Consult eBook version included with purchase. This enhanced eBook experience includes access -- on a variety of devices -- to the complete text, videos, images, and references from the book. Thoroughly updated chapters include the latest information on the human microbiome and probiotics/prebiotics; including a new chapter on Human Microbiome In Health and Disease. NEW chapter summaries introduce each microbe chapter, including trigger words and links to the relevant chapter text (on e-book version on Student Consult), providing a concise introduction or convenient review for each topic. Online access to the complete text, additional images, 200 self-assessment questions, NEW animations, and more is available through Student Consult.
Download or read book Medical Microbiology written by Patrick R. Murray and published by Elsevier Health Sciences. This book was released on 2020-03-10 with total page 987 pages. Available in PDF, EPUB and Kindle. Book excerpt: The foremost text in this complex and fast-changing field, Medical Microbiology, 9th Edition, provides concise, up-to-date, and understandable explanations of key concepts in medical microbiology, immunology, and the microbes that cause human disease. Clear, engaging coverage of basic principles, immunology, laboratory diagnosis, bacteriology, virology, mycology, and parasitology help you master the essentials of microbiology?effectively preparing you for your coursework, exams, and beyond. Features significant new information on the human microbiome and its influence on the immune and other body systems, and new developments in microbial diagnosis, treatment, diseases, and pathogens. Updates every chapter with state-of-the-art information and current literature citations. Summarizes detailed information in tabular format rather than in lengthy text. Provides review questions at the end of each chapter that correlate basic science with clinical practice. Features clinical cases that illustrate the epidemiology, diagnosis, and treatment of infectious diseases. Introduces microbe chapters with summaries and trigger words for easy review. Highlights the text with clear, colorful figures, clinical photographs, and images that help you visualize the clinical presentation of infections. Offers additional study features online, including 200 self-assessment questions, microscopic images of the microbes, videos, and a new integrating chapter that provides hyperlinks between the microbes, the organ systems that they affect, and their diseases. Evolve Instructor site with an image and video collection is available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com.
Download or read book Principles of Mucosal Immunology written by Phillip D. Smith and published by Garland Science. This book was released on 2020-04-21 with total page 957 pages. Available in PDF, EPUB and Kindle. Book excerpt: This respected graduate-level textbook provides comprehensive and accessible coverage of the basic and clinical aspects of the mucosal immune system, addressing the major components of the mucosal barrier ̶ gastrointestinal, upper and lower respiratory, ocular, and genitourinary mucosal immune systems ̶ in a highly user-friendly style. The editors of and contributors to the book, all internationally-recognized leaders, present the current principles, concepts, and basic processes involved in mucosal immunology, mucosal diseases, and host defense at mucosal surfaces. Topics discussed include the development and structure of the mucosal immune system and its cellular constituents, host-microbe relationships, infection, mucosal diseases, and vaccines. The second edition has been carefully updated throughout to reflect the latest developments from clinical research and key literature has been fully updated.
Download or read book Ascaris written by Celia Holland and published by Newnes. This book was released on 2013-05-09 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book tackles a number of different perspectives concerning the parasitic helminth Ascaris, both in animals and in humans and the disease known as ascariasis. It seeks to identify interesting, exciting and novel aspects, which will interest readers from a broad range of disciplines.Over a quarter of the world's population are infected with the human roundworm, and the equivalent in pigs is equally ubiquitous. Both contribute to insidious and chronic nutritional morbidity, and this has been quantified, in humans, as disability adjusted life years approximating 10.5 million. Ascaris larvae develop in host parenteral tissues, and the resultant pathology has been condemnation. Ascariasis, despite its staggering global prevalence and the sheer numbers of people it infects, remains a classic neglected disease. However, renewed interest in the consequences of early infection with worms from the perspective of immune modulation, co-infections and the development of allergy further enhances the relevance of these parasites. Brings together a wide range of topics and approaches and recent, comprehensive and progressive research concerning the neglected parasite Ascaris Provides a blueprint of how a single parasite entity can stimulate interest in basic biology, clinical science, veterinary science, public health and epidemiology Presents a wealth of new insights given that a book on this parasite has not been published for over 20 years 16 chapters from a range of top authors from around the world
Download or read book Medical Microbiology written by Patrick R. Murray and published by Elsevier Health Sciences. This book was released on 2008-12-21 with total page 959 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this popular text presents microbiology in a succinct, easy-to-use, and engaging manner. Clear discussions explain how microbes cause disease in humans, and review the updated vaccines and new antibiotics currently available to treat these diseases. Expert coverage of basic principles, the immune response, laboratory diagnosis, bacteriology, virology, mycology, and parasitology ensures that you’ll understand all the facts vital to the practice of medicine today. A revised artwork program illustrates the appearance of disease, simplifying complex information, while text boxes and additional summary tables emphasize essential concepts and learning issues for more efficient exam review. Online access to Student Consult-where you’ll find the complete contents of the book, fully searchable...Integration Links to bonus content in other Student Consult titles...updated features for both students and instructors...and much more-further enhances your study and exponentially boosts your reference power. Focuses on why the biologic properties of organisms are important to disease in humans, equipping you with a practical understanding of microbiology. Examines etiology, epidemiology, host defenses, identification, diagnosis, prevention, and control for each microbe in consistently organized chapters, enabling you to find the information you need fast. Features summary tables and text boxes that emphasize essential concepts and learning issues, enabling you to make your exam review more efficient. Correlates basic science with clinical practice through review questions at the end of each chapter to help you understand the clinical relevance of the organisms examined. Uses clinical cases from literature reports to illustrate the epidemiology, diagnosis, and treatment of infectious diseases. Features revised artwork-more than 635 brilliant images, nearly all in full color-that offers a more consistent and modern approach to the study of medical microbiology. Provides more clinical photographs throughout that help you better understand the clinical applications of microbiology. Offers expanded use of summary boxes for bacteria throughout all organism chapters to further enhance your review and learning. Includes enhanced Student Consult features including self-assessment questions, clinical cases, animations showing the actions of various important toxins, and a PowerPoint presentation with supplemental images of organisms and stains.
Download or read book Haemonchus Contortus and Haemonchosis Past Present and Future Trends written by and published by Academic Press. This book was released on 2016-05-27 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Haemonchus Contortus and Haemonchosis – Past, Present and Future Trends, the latest in the Advances in Parasitology series first published in 1963, contains comprehensive and up-to-date reviews on all areas of interest in contemporary parasitology. The series includes medical studies of parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which help to shape current thinking and applications. The 2014 impact factor is 6.226. Informs and updates on all the latest developments in the field of parasitology Contains contributions from leading authorities and industry experts
Download or read book Helminthiasis written by Omolade Olayinka Okwa and published by BoD – Books on Demand. This book was released on 2020-02-19 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Helminthiasis is a disease caused by parasitic helminths such as flukes, tapeworms, filarial worms, and nematodes. These parasites cause diseases that pose serious health problems, especially in developing countries of the world. Helminthiasis is a reflection of poor socio-economic conditions, which impacts on the social life of victims and economic development. Parasitic helminths live in a variety of habitats in their hosts and are far more widespread than we think. Gastrointestinal helminths are the largest group that affects their host directly through feacal-oral routes. This book not only provides insight into antihelminthic resistance in livestock but it also discusses soil transmitted helminths in pregnant women and children and filariasis as a debilitating disease. The book covers the prevention and control of helminthiasis of which adequate diagnosis is crucial. This book helps to close the information gap on helminthiasis, which has otherwise been classified as belonging to the group of neglected diseases and overlooked as a serious cause of morbidity and mortality of humans and domestic animals. The information in this book proposes that helminthiasis needs more global attention.
Download or read book Fish Parasites written by Woo and published by CABI. This book was released on 2011 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on pathobiology and protective strategies against protozoan and metazoan parasites of fish, this book reviews the latest research on important parasites: those that cause financial hardships to the aquaculture industry, have been introduced to new geographical regions through transportation of infected fish, are pathogenic to groups of finfish and detrimental to production, are highly adaptable and not host-specific with worldwide distributions, and that may serve as disease models for studies on other pathogens. It also highlights gaps in the knowledge to help direct future research.
Download or read book Medical Parasitology written by Ruth Leventhal and published by F.A. Davis. This book was released on 2019-10-28 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rely on this concise, systematic introduction to the biology and epidemiology of human parasitic diseases. Explore an extensive series of photographs, line drawings, and plates that aid in the recognition of medically-relevant parasites and help to build a solid understanding of the fundamentals of diagnosis and treatment.
Download or read book Pyrantel Parasiticide Therapy in Humans and Domestic Animals written by Alan A Marchiondo and published by Academic Press. This book was released on 2016-06-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pyrantel Parasiticide Therapy in Humans and Domestic Animals presents a single source history and reference on the parasiticide activity and pharmacology of the tetrahydropyrimidines and their salts in humans and domestic animals, also collating evidence that resistance to pyrantel has developed in human and domestic animal nematodes. Other books of this nature have been compiled historically for specific anthelmintic compounds, but none has been written to date for the pyrantel family of drugs. Pyrantel, a nicotinic receptor agonist, has been used in domestic animal and human medicine since the 1970's to control two important nematode groups, the hookworms and the roundworms. Given the zoonotic potential of these parasites, pyrantel has served a dual role in helping to protect the health of both domestic animals and the public for more than 45 years.
Download or read book Pharmacology for Nursing Care E Book written by Richard A. Lehne and published by Elsevier Health Sciences. This book was released on 2014-06-25 with total page 1483 pages. Available in PDF, EPUB and Kindle. Book excerpt: A favorite among nursing students, Pharmacology for Nursing Care, 8th Edition, features a uniquely engaging writing style, clear explanations, and unmatched clinical precision and currency to help you gain a solid understanding of key drugs and their implications -- as opposed to just memorization of certain facts. Compelling features such as a drug prototype approach, use of large and small print to distinguish need-to-know versus nice-to-know content, and a focus on major nursing implications save you study time by directing your attention on the most important, need-to-know information. The new edition also features an abundance of content updates to keep you ahead of the curve in school and in professional practice. UNIQUE! Engaging writing style with clear explanations makes content easy to grasp and even enjoyable to learn. A drug prototype approach uses one drug within each drug family to characterize all members of its group to help you learn about related drugs currently on the market and drugs that will be released once you begin practice. UNIQUE! Special Interest Topic boxes address timely issues in pharmacology and connect pharmacology content with current trends. Large print/small print design distinguishes essential "need-to-know" information from "nice-to-know" information. Limited discussion of adverse effects and drug interactions keeps your limited study time focused on only the most clinically important information. Reliance on up-to-date evidence-based clinical guidelines ensures that therapeutic uses are clinically relevant. Integrated and summarized nursing content demonstrates the vital interplay between drug therapy and nursing care. Coverage of dietary supplements and herbal interactions equips you to alert patients and caregivers to the potential dangers of certain dietary supplements, including interactions with prescribed and over-the-counter drugs and herbal therapies. Additional learning features provide a touchstone for study and review as you complete reading assignments and build a foundation of pharmacologic knowledge.
