Download or read book PAIN Novel targets and new technologies written by Susan Hua and published by Frontiers Media SA. This book was released on 2015-01-22 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: The problem of clinical pain management is complex and far-reaching, as it encompasses many different types of pain, such as arthritis, musculoskeletal conditions, neuropathic pain, and visceral pain. It is widely known that many of the well-established analgesic pathways are centrally based, involving spinal and supraspinal sites. However, pain can also be effectively controlled by peripheral pathways. The analgesics market is growing and the driving forces are the aging population and need for better therapeutic benefits. There are various analgesic products that are available that can be administered by various routes, yet research is active in identifying new technologies for better drug targeting and novel targets to gain improved therapeutic efficiency. This e-Book “PAIN – novel targets and new technologies” has brought together experts in the field of pain at the physiological, pharmacological and pharmaceutical levels to discuss novel pain targets and new pain technologies across the various types of pain. This information is presented as novel research findings, short communications and review articles. The goal of this e-Book is to generate further collaborative discussion on the future and direction of pain therapies.
Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-10-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
Download or read book Translational Pain Research written by Lawrence Kruger and published by CRC Press. This book was released on 2009-11-24 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical
Download or read book Spinal Cord Injury Pain written by Christine N. Sang and published by Elsevier. This book was released on 2021-10-21 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spinal Cord Injury Pain presents the basis for preclinical and clinical investigations, along with strategies for new approaches in the treatment of central neuropathic pain. Contributors from the private sector and academia provide a comprehensive review of state-of-the-art research in this challenging space. Topics include Epidemiology of Chronic Pain Following SCI, experimental models and mechanisms of chronic pain in SCI, and new targets and technologies. This book serves as a resource for continued translational research that will result in novel approaches and treatments that improve function and quality of life for individuals with CNP/SCI. Despite a better understanding of the complexity of mechanisms of CNP/SCI, improved medical and surgical management of SCI, and the subsequent acceleration of the identification of new targets and the development of novel analgesics, there is still a great unmet clinical need in the area of CNP following SCI. Hence, this book is a welcomed addition to current research and developments. - Provides a comprehensive resource for novel approaches and treatments that improve function and quality of life for individuals with CNP/SCI - Includes contributors from the private sector and academia - Covers epidemiology of chronic pain following SCI, experimental models, mechanisms of chronic pain in SCI, and new targets and technologies
Download or read book Pain Care Essentials and Innovations written by Sanjog Pangarkar and published by Elsevier Health Sciences. This book was released on 2020-06-30 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the newest trends and treatments in pain care, as well as the pain treatment strategies that have been successfully employed in the past, Pain Care Essentials and Innovations brings you fully up to date with effective treatments for acute and chronic pain. It offers expert guidance on both interventional and non-interventional strategies, provided by respected academic physiatrists who practice evidence-based medicine at UCLA and an ACGME-accredited rehabilitation and pain program. Covers cannabinoids in pain care, novel therapeutics in pain medicine, and integrative care in pain management. Discusses relevant basic science, psychological aspects of pain care, opioids and practice guidelines, geriatric pain management, and future research in the field. Consolidates today’s available information and guidance into a single, convenient resource.
Download or read book Relieving Pain in America written by Institute of Medicine and published by National Academies Press. This book was released on 2011-10-26 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic pain costs the nation up to $635 billion each year in medical treatment and lost productivity. The 2010 Patient Protection and Affordable Care Act required the Department of Health and Human Services (HHS) to enlist the Institute of Medicine (IOM) in examining pain as a public health problem. In this report, the IOM offers a blueprint for action in transforming prevention, care, education, and research, with the goal of providing relief for people with pain in America. To reach the vast multitude of people with various types of pain, the nation must adopt a population-level prevention and management strategy. The IOM recommends that HHS develop a comprehensive plan with specific goals, actions, and timeframes. Better data are needed to help shape efforts, especially on the groups of people currently underdiagnosed and undertreated, and the IOM encourages federal and state agencies and private organizations to accelerate the collection of data on pain incidence, prevalence, and treatments. Because pain varies from patient to patient, healthcare providers should increasingly aim at tailoring pain care to each person's experience, and self-management of pain should be promoted. In addition, because there are major gaps in knowledge about pain across health care and society alike, the IOM recommends that federal agencies and other stakeholders redesign education programs to bridge these gaps. Pain is a major driver for visits to physicians, a major reason for taking medications, a major cause of disability, and a key factor in quality of life and productivity. Given the burden of pain in human lives, dollars, and social consequences, relieving pain should be a national priority.
Download or read book Chronic Pain and Brain Abnormalities written by Carl Y. Saab and published by Academic Press. This book was released on 2013-06-28 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only natural for someone in pain to attend to the body part that hurts. Yet this book tells the story of persistent pain having negative effects on brain function. The contributors, all leading experts in their respective fields of pain electrophysiology, brain imaging, and animal models of pain, strive to synthesize compelling and, in some ways, connected hypotheses with regard to pain-related changes in the brain. Together, they contribute their clinical, academic, and theoretical expertise in a comprehensive overview that attempts to define the broader philosophical context of pain (disentangling sensical from nonsensical claims), list the changes known to take place in the brains of individuals with chronic pain and animal models of pain, address the possible causes and mechanisms underlying these changes, and detail the techniques and analytical methods at our disposal to "visualize" and study these changes. - Philosophical and social concepts of pain; testimonials of chronic-pain patients - Clinical data from pain patients' brains - Advances in noninvasive brain imaging for pain patients - Combining theoretical and empirical approaches to the analysis of pain-related brain function - Manipulation of brain function in animal models - Emerging neurotechnology principles for pain diagnostics and therapeutics
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Download or read book The Brain and Pain written by Richard Ambron and published by Columbia University Press. This book was released on 2022-03-01 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain is an inevitable part of existence, but severe debilitating or chronic pain is a pathological condition that diminishes the quality of life. The Brain and Pain explores the present and future of pain management, providing a comprehensive understanding based on the latest discoveries from many branches of neuroscience. Richard Ambron—the former director of a neuroscience lab that conducted leading research in this field—explains the science of how and why we feel pain. He describes how the nervous system and brain process information that leads to the experience of pain, detailing the cellular and molecular functions that are responsible for the initial perceptions of an injury. He discusses how pharmacological agents such as opiates affect the duration and intensity of pain. Ambron examines new evidence showing that discrete circuits in the brain modulate the experience of pain in response to a placebo, fear, anxiety, belief, or other circumstances, as well as how pain can be relieved by activating these circuits using mindfulness training and other nonpharmacological treatments. The book also evaluates the prospects of procedures such as deep brain stimulation and optogenetics. Current and thorough, The Brain and Pain will be invaluable for a range of people seeking to understand their options for treatment as well as students in neuroscience and medicine.
Download or read book Anticancer Drug Development written by Bruce C. Baguley and published by Elsevier. This book was released on 2001-11-17 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided. - One work that can be consulted for all aspects of anticancer drug development - Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts - A wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death - Detailed descriptions of the sources of new anticancer drugs, including combinatorial chemistry, phage display, and natural products - Discussion of how new drugs can be tested in preclinical systems, including the latest technology of robotic assay systems, cell culture, and experimental animal techniques - Hundreds of references that allow the reader to access relevant scientific and medical literature - Clear illustrations, some in color, that provide both understanding of the field and material for teaching
Download or read book Epilipidome as a New Level of Cellular Regulation written by Maria Fedorova and published by Frontiers Media SA. This book was released on 2022-04-27 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Behavioral and Psychopharmacologic Pain Management written by Michael H. Ebert and published by Cambridge University Press. This book was released on 2010-11-25 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain is the most common symptom bringing a patient to a physician's attention. Physicians training in pain medicine may originate from different disciplines and approach the field with varying backgrounds and experience. This book captures the theory and evidence-based practice of behavioral, psychotherapeutic and psychopharmacological treatments in modern pain medicine. The book's contributors span the fields of psychiatry, psychology, anesthesia, neurology, physical medicine and rehabilitation, and nursing. Thus the structure and content of the book convey the interdisciplinary approach that is the current standard for the successful practice of pain management. The book is designed to be used as a text for training fellowships in pain medicine, as well as graduate courses in psychology, nursing, and other health professions.
Download or read book Postoperative Pain Management written by F. Michael Ferrante and published by . This book was released on 1993 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Acceptance and Commitment Therapy for Chronic Pain written by JoAnne Dahl and published by New Harbinger Publications. This book was released on 2005-04-05 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Professionals who work with patients and clients struggling with chronic pain will benefit from this values-based behavior change program for managing the effects of pain. Acceptance and Commitment Therapy for Chronic Pain addresses case formulation and clinical techniques for working with pain patients through a combination of practical instruction and a treatment scenario narrative that follows a patient through an ACT-based intervention. An invaluable resource for rehabilitation specialists, psychologists, physicians, nurses, and others.
Download or read book Fundamentals of Pain Medicine written by Jianguo Cheng and published by Springer. This book was released on 2018-02-08 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Characterized by clarity and straddling the line between scope and depth of information, this concise book provides physicians a comprehensive overview of pain medicine. Chapters are written by some of the leading minds in pain medicine and feature case studies, key points and suggested readings. Multidisciplinary approaches to the clinical and financial challenges of pain with the goal of improving patient quality of life are also discussed. Additionally, the book is in is in tight alignment with the information that trainees are expected to master for the American Board of Anesthesiology’s pain medicine subspecialty certification, as outlined by the Joint Council on Anesthesiology Examinations; it covers the diagnosis of pain states, the management of pain, acute pain, radicular pain, neuropathic pain, chronic visceral pain, headaches, and special populations. This book is a must-have for anyone new to pain medicine or studying for the subspecialty certification.
Download or read book The Pain Management Workbook written by Rachel Zoffness and published by New Harbinger Publications. This book was released on 2020-12-01 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Change your brain, change your pain with this powerful, evidence-based workbook. If you’re struggling with chronic pain, you’re not alone: more than one hundred million Americans currently live with chronic pain. Yet, despite its prevalence, chronic pain is not well understood. Fortunately, research has emerged showing the effectiveness of a treatment model for pain management grounded in biology, psychology, and social functioning. In this groundbreaking workbook, you’ll find a comprehensive outline of this effective biopsychosocial approach, as well as scientifically supported interventions rooted in cognitive- behavioral therapy (CBT), mindfulness, and neuroscience to help you take control of your pain—and your life! You’ll learn strategies for creating a pain plan for home and work, reducing reliance on medications, and breaking the pain cycle. Also included are tips for improving sleep, nutrition for pain, methods for resuming valued activities, and more. If you’re ready to take your life back from pain, this workbook has everything you need to get started.
Download or read book Pain Free written by Pete Egoscue and published by Bantam. This book was released on 2014-06-25 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Starting today, you don't have to live in pain. “This book is extraordinary, and I am thrilled to recommend it to anyone who’s interested in dramatically increasing the quality of their physical health.”—Tony Robbins That is the revolutionary message of this breakthrough system for eliminating chronic pain without drugs, surgery, or expensive physical therapy. Developed by Pete Egoscue, a nationally renowned physiologist and sports injury consultant to some of today’s top athletes, the Egoscue Method has an astounding 95 percent success rate. The key is a series of gentle exercises and carefully constructed stretches called E-cises. Inside you’ll find detailed photographs and step-by-step instructions for dozens of e-cizes specifically designed to provide quick and lasting relief of: • Lower back pain, hip problems, sciatica, and bad knees • Carpal tunnel syndrome and even some forms of arthritis • Migraines and other headaches, stiff neck, fatigue, sinus problems, vertigo, and TMJ • Shin splints, varicose veins, sprained or weak ankles, and many foot ailments • Bursitis, tendinitis, and rotator cuff problems Plus special preventive programs for maintaining health through the entire body. With this book in hand, you’re on your way to regaining the greatest gift of all: a pain-free body!
