Download or read book Paediatric Research written by M. Adinolfi and published by Cambridge University Press. This book was released on 1982-04-22 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subjects reviewed in this Monograph span a wide and exciting field, reflecting many different specialities. They are, however, also closely interrelated as they reflect the eclectic nature of Professor Paul Polani's intellectual interests. The chapters are written by present and past members of his Unit - a Unit internationally recognized for its astute and stimulating discoveries and innovations. The chapters pay tribute to the fact that Paul Polani's viewpoint is that a multidisciplinary approach to the subject of disease is most effective when motivated by genetic philosophy. On this theme the book provides insight into the latest ideas on the genetics of handicap - including counselling, population cytogenetics, prevention of biochemical genetic disorders, repairing genetic damage, the epidemiology of congenital defects, and the prevention of neural-tube defects. All these and the other chapters provide an essential basis for understanding the fields of prevention and treatment.
Download or read book Guide to Paediatric Drug Development and Clinical Research written by Klaus Rose and published by Karger Medical and Scientific Publishers. This book was released on 2010-01-01 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Children in the developed world have never enjoyed better medical care: mortality has decreased and many fatal diseases of the past can today be prevented or even cured. However, the current practice of pharmacotherapy in children does not reflect existing scientific knowledge and has come under scrutiny by paediatricians, pharmacists and regulatory authorities. In order to advance the development of medicines tailored to paediatric needs, US and EU legislators have taken action, and the WHO has initiated a global paediatric campaign. This book gives an overview over the worldwide activities that increasingly include children in the development of new medicines. Triggered by both a better understanding of how the child's body develops as well as recent legislation in the USA and in Europe, this comprises dosing, ethics, age-appropriate pharmaceutical forms and clinical trials, to name just a few aspects.A wide spectrum of readers will profit from this book, including paediatricians, pharmacists, general practitioners and health care professionals involved in child care and paediatric research, clinical trial personnel, patient advocacy groups, ethics committees, politicians, parents and interested lay persons.
Download or read book Guide to Paediatric Clinical Research written by Klaus Rose and published by Karger Medical and Scientific Publishers. This book was released on 2007 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: As off-label use of medicines in children is no longer acceptable today, paediatric drug development is currently in transition from an almost exclusive academic specialty towards an integrated part of the global process that drives the development of new pharmaceuticals. US and EU governments have made it mandatory for the pharmaceutical industry to investigate medicines in children, thus exposing a multitude of different institutions to paediatric research. Written by exponents of the academia as well as the pharmaceutical industry, regulators and patient advocacy groups, this book explains the background of the US and EU paediatric legislations, gives an analysis of their probable short-, mid- and long-term impact, addresses key operational challenges in paediatric research, and develops a tentative vision where paediatric drug development needs to go. Helping to understand the role of the different stakeholders, the spectrum of readers to profit from this book ranges from paediatricians, general medical personnel and pharmacologists to those involved in regulatory affairs and clinical trials, pharmaceutical company management, patient advocacy groups, ethical committees, politicians and interested lay persons.
Download or read book Paediatric Bronchoscopy written by K.N. Priftis and published by Karger Medical and Scientific Publishers. This book was released on 2010-05-06 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an in-depth 'state-of-the-art' critical review of the technique and the applications of flexible and rigid bronchoscopy to infants and children. Written by an international panel of experts, it reviews the technical aspects of the procedure, its common and highly specialized applications as well as its potential alternatives. The chapters are enhanced by a wealth of original figures. A major innovation of the book is the inclusion of online videos from actual bronchoscopies that further illustrate and elaborate on the information provided in the text. The book is addressed to paediatric pulmonologists and otorhinolaryngologists, both experienced and in training, as well as to other personnel who are involved in the performance of the procedures. In addition, it is recommended to pulmonologists for adults and general paediatricians who need to be able to evaluate the usefulness of bronchoscopy for their patients and be aware of its limitations and potential contra-indications.
Download or read book Clinical Research in Paediatric Psychopharmacology written by Philippe Auby and published by Woodhead Publishing. This book was released on 2019-09-15 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Research in Paediatric Psychopharmacology: An Overview of the Ethical, Scientific and Regulatory Aspects provides a practical guide and overview of the ethical, scientific and regulatory aspects of clinical research in pediatric psychopharmacology, also discussing practical points to consider when developing clinical research in this field. The book is ideal for professionals involved in clinical research in pediatric psychopharmacology, i.e., including, but not limited to pediatricians, health care professionals, researchers, investigators, pharmaceutical company personals and potentially ethics committee members. Topics discussed include the role of patient organization and advocacy groups in research, the role of families and patients: ‘should I involve my kid in clinical research, and historical, ethical, regulatory, clinical, scientific, intercultural and practical aspects of clinical research in child and adolescent psychopharmacology. Covers both theoretical and practical aspects of clinical research in paediatric psychopharmacology Approaches the topic from different angles from the regulatory framework to the patient perspective Discusses ethical and safety considerations for research in paediatric psychopharmacology Offers future perspective for paediatric development
Download or read book Ethical Conduct of Clinical Research Involving Children written by Institute of Medicine and published by National Academies Press. This book was released on 2004-07-09 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent decades, advances in biomedical research have helped save or lengthen the lives of children around the world. With improved therapies, child and adolescent mortality rates have decreased significantly in the last half century. Despite these advances, pediatricians and others argue that children have not shared equally with adults in biomedical advances. Even though we want children to benefit from the dramatic and accelerating rate of progress in medical care that has been fueled by scientific research, we do not want to place children at risk of being harmed by participating in clinical studies. Ethical Conduct of Clinical Research Involving Children considers the necessities and challenges of this type of research and reviews the ethical and legal standards for conducting it. It also considers problems with the interpretation and application of these standards and conduct, concluding that while children should not be excluded from potentially beneficial clinical studies, some research that is ethically permissible for adults is not acceptable for children, who usually do not have the legal capacity or maturity to make informed decisions about research participation. The book looks at the need for appropriate pediatric expertise at all stages of the design, review, and conduct of a research project to effectively implement policies to protect children. It argues persuasively that a robust system for protecting human research participants in general is a necessary foundation for protecting child research participants in particular.
Download or read book Paediatric Medicines written by Great Britain: Parliament: House of Lords: European Union Committee and published by The Stationery Office. This book was released on 2006-02-02 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 50 per cent of all medicines given to children (and about 90 per cent of those given to the newly-born) have never been tested or authorised for use on them. The Committee's report examines the European Commission's proposal to introduce a Regulation (the Clinical Trials Directive) on medicinal products for paediatric use which aims to stimulate the development of medicines for children and lay down rules for testing and approval. Issues discussed include: the need for better regulation of paediatric medicines; the ethical considerations involved in clinical trials on children, including the issue of consent; mechanisms for implementing the Regulation; access to the database of information on clinical trials; the rewards and incentives proposed to stimulate the research and development of medicines; and the legal basis for the regulation under the EC Treaty. The Committee's report recognises the urgent need for effective action at the European level to authorise medicines for paediatric use and gives broad support to the proposed Directive. However, a number of key issues are highlighted, including: the need for improved labelling of medicines; that the guidelines underpinning the Directive should take account of ethical considerations involved to ensure the rights and capacity of children to give informed consent to trials; and concerns are raised about the adequacy of proposed incentive mechanisms.
Download or read book Safe and Effective Medicines for Children written by Institute of Medicine and published by National Academies Press. This book was released on 2012-10-13 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA) were designed to encourage more pediatric studies of drugs used for children. The FDA asked the IOM to review aspects of pediatric studies and changes in product labeling that resulted from BPCA and PREA and their predecessor policies, as well as assess the incentives for pediatric studies of biologics and the extent to which biologics have been studied in children. The IOM committee concludes that these policies have helped provide clinicians who care for children with better information about the efficacy, safety, and appropriate prescribing of drugs. The IOM suggests that more can be done to increase knowledge about drugs used by children and thereby improve the clinical care, health, and well-being of the nation's children.
Download or read book Paediatric Patient and Family Centred Care Ethical and Legal Issues written by Randi Zlotnik Shaul and published by Springer Science & Business. This book was released on 2014-04-16 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with a theoretical and practical understanding of two health care delivery models: the patient/child centred care and family-centred care. Both are fundamental to caring for children in healthcare organizations. The authors address their application in a variety of paediatric healthcare contexts, as well as an understanding of legal and ethical issues they raise. Each model is increasingly pursued as a vehicle for guiding the delivery of health care in the best interests of children. Such models of health care delivery shape health care policies, programs, facility design, resource allocation decisions and day-to-day interactions among patients, families, physicians and other health care professionals. To maximize the health and ethical benefits these models offer, there must be shared understanding of what the models entail, as well as the ethical and legal synergies and tensions they can create. This book is a valuable resource for paediatricians, nurses, trainees, graduate students, practitioners of ethics and health policy.
Download or read book Pediatric Neuropsychology written by Elise K. Hodges and published by Taylor & Francis. This book was released on 2022-12-05 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric Neuropsychology: Perspectives in an Ambulatory Care Setting provides an overview of the most commonly seen disorders in outpatient settings including ADHD, Autism, congenital heart disease, blood cancer and hematologic conditions, brain tumors, and epilepsy. Each chapter provides up-to-date information on these pediatric neurodevelopmental and medical disorders, including a review of the neuroanatomic contributions as well as an overview of the neuropsychological findings. Alongside the neuroanatomic and neuropsychological underpinnings, case examples and intervention recommendations are provided for parents, educators and others who work with these populations, to enhance the ecological validity of neuropsychological assessments. With reference to the latest diagnostic criteria, this book is an invaluable resource for neuropsychologists or neuropsychology students whose work includes pediatric patients with neurodevelopmental and neuro medical disorders. It is designed to provide practical information but also the most up to date research in neurobiological and neuroanatomical contributions of these disorders to inform the practitioner and enhance the care provided to their pediatric patients.
Download or read book Paediatric Research written by World Health Organization. Scientific Group on Paediatric Research and published by . This book was released on 1968 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Paediatric Drug Handling written by Ian Costello and published by Pharmaceutical Press. This book was released on 2007 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of all of the issues pharmacists serving pediatric patients must consider. Chapters relating to pharmacogenomics, medication error prevention, compounding, and government regulations are extremely informative.
Download or read book Red Book written by American Academy of Pediatrics. Committee on Infectious Diseases and published by . This book was released on 2006 with total page 1040 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Paediatric Clinical Pharmacology written by Evelyne Jacqz-Aigrain and published by CRC Press. This book was released on 2021-02-25 with total page 830 pages. Available in PDF, EPUB and Kindle. Book excerpt: The treatment of children with medicinal products is an important scientific area. It is recognized that many medicines that are used extensively in pediatric patients are either unlicensed or off-label. This textbook will help pediatric health professionals effectively treat children with the most appropriate medicine with minimal side effects.
Download or read book Exercise and Respiratory Diseases in Paediatrics written by Craig A. Williams and published by Routledge. This book was released on 2021-09-24 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is commonly accepted that "exercise is good for children" but, considering the number of children worldwide exercising, we know comparatively little, compared to adults, about how specific mechanisms influence health and sports performance. There are considerable obstacles that challenge the progress of paediatric research, not least in relation to ethical and methodological considerations. Therefore, advances in the science and clinical application of paediatric exercise physiology, psychology and biomechanics have not reached their potential. Paediatric clinical exercise physiology has application to the role of exercise in the assessment and treatment of paediatric chronic diseases, the utilization of physical activity in preventing illness and enhancing wellbeing and can enhance our understanding of how sports can be made safer and more enjoyable for our young athletes. Exercise and Respiratory Diseases in Paediatrics highlights research by various methodologies, including literature reviews, experimental research and innovations, applied to children and adolescents with respiratory diseases. Chronic conditions such as asthma, bronchiectasis (e.g., cystic fibrosis), and those associated with prematurity and medical complexity are worldwide health problems for young people and although management includes pharmaceutical medications, physiotherapy, nutritional and psychological support, exercise has a role in optimising multidisciplinary care. There has been unprecedented acceleration in new technologies and methodologies that promise to facilitate paediatric research and these are explained and discussed as future research directions. This is reading for post graduate students, researchers, academics and policy makers within the field of paediatric healthcare, physical activity, physiology and the related disciplines.
Download or read book Phosphate in Paediatric Health and Disease written by U. Alon and published by CRC Press. This book was released on 2018-05-04 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: * Provides a state-of-the-art overview* Reviews the developmental physiology of phosphate metabolism from the fetus to the adolescent* Describes the pathophysiologic mechanisms associated with perturbations in phosphate homeostasis
Download or read book Hatch Sumner s Textbook of Paediatric Anaesthesia Third edition written by Robert Bingham and published by CRC Press. This book was released on 2008-06-27 with total page 809 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hatch and Sumner's Paediatric Anaesthesia is a thorough revision and update of the extremely popular 'Paediatric Anaesthesia' by Edward Sumner and David Hatch. A new editorial team has carefully revised the text and developed it into a concise textbook that provides all the information that a trainee or practising paediatric anaesthetist should kno
