Download or read book Oxygen Availability to Sensors Implanted in Tissue written by Michael Emanuel Miller and published by . This book was released on 1998 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Long term Oxygen Sensor Implantation in the Porcine Subcutaneous Environment written by Lucas Stefan Kumosa and published by . This book was released on 2011 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: The effect of long-term implantation on metabolically active devices is of utmost importance for not only the success of implanted glucose sensors used in diabetic therapy, but also for the development of artificial tissues and encapsulated cell devices. Such devices are dependent on the constant, predictable supply of metabolites from the local vasculature. Long-term implantation leads to the formation of a foreign body capsule whose purpose is the protection of the host and isolation of the foreign material from local tissue resources. While this encapsulation is successful in protecting tissues from invading agents, metabolite flow continues, albeit at greatly reduced levels. The understanding of this encapsulation process is critical for the design and successful implementation of active implants dependent on metabolite supply. The project goal is to utilize implantable wireless telemeters designed and manufactured by Glysens, Inc. to understand changes in oxygen levels of the surrounding subcutaneous tissues over the course of implantation in pigs. This is performed in three distinct, yet interrelated parts, namely: the analysis of oxygen signals collected from the long-term implantation of telemeters, the histological analysis of serial tissue samples collected from regions adjacent to the telemeter-like shams over the course of implantation, and the investigation of an accurate model for the dynamics of metabolite supply to implanted devices over the long-term. Oxygen signals collected from sensors implanted into the subcutaneous tissues of pigs were found to contain several salient features. First, a long-term trend exhibiting exponential decay properties was discovered and is attributed to the impedance of mass transfer by the formation of a thick, avascular, fibrous foreign body capsule. The existence of such a capsule is demonstrated via histological examinations, and its impact on mass transfer of oxygen from the underlying vasculature to implant surface is investigated utilizing analytical and numerical methods. Second, a dominant frequency with a period of oscillation of 7-14 days was found for most of the signals examined. A model is proposed detailing the critical components of such an oscillations and how they might correlate with specific stages of the wound healing response. The successful completion of this project provide a better understanding of the tissue changes that occur during the foreign body reaction, and the findings will be of direct benefit to the implant and device community allowing for better design parameters and device performance.

Download or read book Glucose and Oxygen Sensors Implanted in the Subcutaneous Tissue written by Sima Ertefai and published by . This book was released on 1989 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Measuring Oxidants and Oxidative Stress in Biological Systems written by Lawrence J. Berliner and published by Springer Nature. This book was released on 2020-08-08 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the methods of analysis and determination of oxidants and oxidative stress in biological systems. Reviews and protocols on select methods of analysis of ROS, RNS, oxygen, redox status, and oxidative stress in biological systems are described in detail. It is an essential resource for both novices and experts in the field of oxidant and oxidative stress biology.

Download or read book Oxygen Transport to Tissue XXXIX written by Howard J. Halpern and published by Springer. This book was released on 2017-07-06 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents all aspects of delivery of oxygen to tissues and tumors in peer reviewed short articles. Both overview and the most recent, advanced techniques for oxygen measurement are presented. Articles and peer reviewers include those from leaders in their field. Topics such as molecular signaling in the organismal and tumor response to low levels of local oxygenation, hypoxia inducible factor (HIF) , cancer metabolism, individual human and animal response to oxygen changes monitored by optical/near infrared spectroscopy/ tomography to novel electron resonance spectroscopy and spectroscopic imaging, instrumentation, progress in blood substitute research, retinal physiology, cellular hypoxia, mitochondrial function; brain oxygenation and function; oxygen transport in sports, hypoxia in diseases and clinical care. Chapters 10 and 19 of this book are open access under a CC BY 4.0 license.

Download or read book Glucose Monitoring Devices written by Chiara Fabris and published by Academic Press. This book was released on 2020-06-02 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glucose Monitoring Devices: Measuring Blood Glucose to Manage and Control Diabetes presents the state-of-the-art regarding glucose monitoring devices and the clinical use of monitoring data for the improvement of diabetes management and control. Chapters cover the two most common approaches to glucose monitoring–self-monitoring blood glucose and continuous glucose monitoring–discussing their components, accuracy, the impact of use on quality of glycemic control as documented by landmark clinical trials, and mathematical approaches. Other sections cover how data obtained from these monitoring devices is deployed within diabetes management systems and new approaches to glucose monitoring. This book provides a comprehensive treatment on glucose monitoring devices not otherwise found in a single manuscript. Its comprehensive variety of topics makes it an excellent reference book for doctoral and postdoctoral students working in the field of diabetes technology, both in academia and industry. Presents a comprehensive approach that spans self-monitoring blood glucose devices, the use of continuous monitoring in the artificial pancreas, and intraperitoneal glucose sensing Provides a high-level descriptions of devices, as well as detailed mathematical descriptions of methods and techniques Written by experts in the field with vast experience in the field of diabetes and diabetes technology

Download or read book Implantable Sensors and Systems written by Guang-Zhong Yang and published by Springer. This book was released on 2018-03-27 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implantable sensing, whether used for transient or long-term monitoring of in vivo physiological, bio-electrical, bio-chemical and metabolic changes, is a rapidly advancing field of research and development. Underpinned by increasingly small, smart and energy efficient designs, they become an integral part of surgical prostheses or implants for both acute and chronic conditions, supporting optimised, context aware sensing, feedback, or stimulation with due consideration of system level impact. From sensor design, fabrication, on-node processing with application specific integrated circuits, to power optimisation, wireless data paths and security, this book provides a detailed explanation of both the theories and practical considerations of developing novel implantable sensors. Other topics covered by the book include sensor embodiment and flexible electronics, implantable optical sensors and power harvesting. Implantable Sensors and Systems – from Theory to Practice is an important reference for those working in the field of medical devices. The structure of the book is carefully prepared so that it can also be used as an introductory reference for those about to enter into this exciting research and developing field.

Download or read book Oxygen Transport to Tissue XLII written by Edwin M. Nemoto and published by Springer Nature. This book was released on 2021-05-08 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents cutting-edge papers and perspectives on the transport of oxygen to tissues by scientists in a multitude of disciplines such as biochemistry, engineering, mathematics, medicine, physics, physiology, veterinary and complementary medicine. The book is composed of the following 6 parts: Brain Oxygenation and Function, Tumor Oxygenation and Metabolism, Muscle Oxygenation and Sports Medicine, Cell Metabolism and Tissue Oxygenation, Methodology of O2 Measurements, and Special Topics. The articles in this book have been presented at the 42nd annual meeting of the International Society on Oxygen Transport to Tissue (ISOTT 2019) held in Albuquerque, New Mexico, USA, from July 28 to July 31, 2019. Academics, clinical and industry researchers, engineers, as well as graduate students who are interested in oxygen transport to tissue will find this book a great reference and a useful learning resource.

Download or read book Implantable Sensor Systems for Medical Applications written by Andreas Inmann and published by Elsevier. This book was released on 2013-01-02 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implantable sensor systems offer great potential for enhanced medical care and improved quality of life, consequently leading to major investment in this exciting field. Implantable sensor systems for medical applications provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of these devices in a diverse range of medical applications.Part one reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, microassembly, electrode array design and fabrication, and the use of biofuel cells as sustainable power sources. Part two goes on to consider the challenges associated with implantable systems. Biocompatibility, sterilization considerations and the development of active implantable medical devices in a regulated environment are discussed, along with issues regarding data protection and patient privacy in medical sensor networks. Applications of implantable systems are then discussed in part three, beginning with Microelectromechanical systems (MEMS) for in-vivo applications before further exploration of tripolar interfaces for neural recording, sensors for motor neuroprostheses, implantable wireless body area networks and retina implants.With its distinguished editors and international team of expert contributors, Implantable sensor systems for medical applications is a comprehensive guide for all those involved in the design, development and application of these life-changing technologies. Provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of implantable sensor systems in a range of medical applications Reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, and microassembly Considers the challenges associated with implantable systems, including biocompatibility and sterilization

Download or read book Oxygen Transport to Tissue XLI written by Pan-Dong Ryu and published by Springer Nature. This book was released on 2019-12-31 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents cutting-edge papers and perspectives on the transport of oxygen to tissues by scientists in a multitude of disciplines such as biochemistry, engineering, mathematics, medicine, physics, physiology, veterinary and complementary medicine. The book is composed of the following 6 parts: Brain Oxygenation and Function, Tumor Oxygenation and Metabolism, Muscle Oxygenation and Sports Medicine, Cell Metabolism and Tissue Oxygenation, Methodology of O2 Measurements, and Special Topics. The articles in this book have been presented at the 46th annual meeting of the International Society on Oxygen Transport to Tissue (ISOTT 2018) held in Seoul, Republic of Korea, from July 1 to July 5, 2018. Academics, clinical and industry researchers, engineers, as well as graduate students who are interested in oxygen transport to tissue will find this book a great reference and a useful learning resource.

Download or read book Oxygen Transport to Tissue XXXVI written by Harold M. Swartz and published by Springer Science & Business Media. This book was released on 2014-04-11 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the refereed contributions from the 41st annual meeting of ISOTT. The annual meetings of ISOTT bring together scientists from various fields (medicine, physiology, mathematics, biology, chemistry, physics, engineering, etc.) in a unique international forum. Traditionally, ISOTT conferences are a place, where an atmosphere of interaction is created, where many questions are asked after each presentation and lively discussions occur at a high scientific level. This vivid interaction is the main motivation for members to participate and gain new ideas and knowledge in the broad field of oxygen transport to tissue. The papers in this volume summarize some of the outstanding contributions from the 41st annual meeting. Special features in this volume include invited presentations from senior members of ISOTT for the theme “the wisdom of ISOTT” in which founders, past presidents and prize winners from previous meetings provided both cutting edge new knowledge and integrated overviews of critical aspects of the field. The presentations and manuscripts also include those provided by the special opportunity provided by having part of the ISOTT meeting overlap with the EPR-2013 meeting where both focused on preclinical and clinical measurements of oxygen, with a particular emphasis on cancer. Chapters 22, 24, 25 and 26 are open access under a CC BY 4.0 license via link.springer.com.

Download or read book CMOS Circuits for Biological Sensing and Processing written by Srinjoy Mitra and published by Springer. This book was released on 2017-11-18 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the most comprehensive and consistent survey of the field of IC design for Biological Sensing and Processing. The authors describe a multitude of applications that require custom CMOS IC design and highlight the techniques in analog and mixed-signal circuit design that potentially can cross boundaries and benefit the very wide community of bio-medical engineers.

Download or read book Time correlated single photon counting written by Desmond O'Connor and published by Academic Press. This book was released on 2012-12-02 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Time-correlated Single Photon Counting has been written in the hope that by relating the authors' experiences with a variety of different single photon counting systems, they may provide a useful service to users and potential users of this formidably sensitive technique. Of all the techniques available to obtain information on the rates of depopulation of excited electronic singlet states of molecular species, monitoring of fluorescence provides, in principle, the simplest and most direct measure of concentration. This volume comprises eight chapters, with the first focusing on the time dependence and applications of fluorescence. Succeeding chapters go on to discuss basic principles of the single photon counting lifetime measurement; light sources; photomultipliers; electronics; data analysis; nanosecond time-resolved emission spectroscopy; time dependence of fluorescence anisotropy. This book will be of interest to practitioners in the field of chemistry.

Download or read book An Introductory Text to Bioengineering written by Shu Chien and published by World Scientific. This book was released on 2008 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: This bestselling textbook will introduce undergraduate bioengineering students to the fundamental concepts and techniques, with the basic theme of integrative bioengineering. It covers bioengineering of several body systems, organs, tissues, and cells, integrating physiology at these levels with engineering concepts and approaches; novel developments in tissue engineering, regenerative medicine, nanoscience and nanotechnology; state-of-the-art knowledge in systems biology and bioinformatics; and socio-economic aspects of bioengineering.One of the distinctive features of the book is that it is integrative in nature (integration of biology, medicine and engineering, across different levels of the biological hierarchy, and basic knowledge with applications). It is unique in that it covers fundamental aspects of bioengineering, cutting-edge frontiers, and practical applications, as well as perspectives of bioengineering development. Furthermore, it covers important socio-economical aspects of bioengineering such as ethics and entrepreneurism.

Download or read book Textbook of Neuroanaesthesia and Critical Care written by Basil F. Matta and published by Cambridge University Press. This book was released on 2000 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: All aspects of neuroanaesthesia are covered in this up-to-date, highly illustrated textbook. Written for general anaesthetic departments and ICUs, as well as specialist neurosurgical and trauma units, it covers the key areas needed to understand the principles of neuroanaesthesia, such as functional anatomy, advances in bedside monitoring and imaging techniques. It addresses practical issues of diagnosis and patient care. Best clinical practice is described in detail throughout. It is an essential, one-stop review of modern neuroanaesthesia and neurocritical care for anaesthetists, intensivists and surgeons at all levels of practice.

Download or read book Scaffolding In Tissue Engineering written by Peter X. Ma and published by CRC Press. This book was released on 2005-08-19 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing interest in scaffolding design and increasing research programs dedicated to regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While certain books and journal articles address various aspects in the field, this is the first current, comprehensive text focusing on scaffolding for tissue engineering.

Download or read book Biosensors and Invasive Monitoring in Clinical Applications written by Emma P. Córcoles and published by Springer Science & Business Media. This book was released on 2013-04-23 with total page 83 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines the advances of invasive monitoring by means of biosensors and microdialysis. Physical and physiological parameters are commonly monitored in clinical settings using invasive techniques due to their positive outcome in patients’ diagnosis and treatment. Biochemical parameters, however, still rely on off-line measurements and require large pieces of equipment. Biosensing and sampling devices present excellent capabilities for their use in continuous monitoring of patients’ biochemical parameters. However, certain issues remain to be solved in order to ensure a more widespread use of these techniques in today’s medical practices.