Download or read book Advanced Surfaces for Stem Cell Research written by Ashutosh Tiwari and published by John Wiley & Sons. This book was released on 2016-11-29 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book outlines first the importance of Extra Cellular Matrix (ECM), which is a natural surface for most of cells. In the following chapters the influence of biological, chemical, mechanical, and physical properties of surfaces in micro and nano-scale on stem cell behavior are discussed including the mechanotransduction. Biomimetic and bioinspired approaches are highlighted for developing microenvironment of several tissues, and surface engineering applications are discussed in tissue engineering, regenerative medicine and different type of biomaterials in various chapters of the book. This book brings together innovative methodologies and strategies adopted in the research and development of Advanced Surfaces in Stem Cell Research. Well-known worldwide researchers deliberate subjects including: Extracellular matrix proteins for stem cell fate The superficial mechanical and physical properties of matrix microenvironment as stem cell fate regulator Effects of mechanotransduction on stem cell behavior Modulation of stem cells behavior through bioactive surfaces Influence of controlled micro and nanoengineered surfaces on stem cell fate Nanostructured polymeric surfaces for stem cells Laser surface modification techniques and stem cells applications Plasma polymer deposition: a versatile tool for stem cell research Application of bioreactor concept and modeling techniques in bone regeneration and augmentation treatments Substrates and surfaces for control of pluripotent stem cell fate and function Application of biopolymer-based, surface modified devices in transplant medicine and tissue engineering Silk as a natural biopolymer for tissue engineering

Download or read book Stem Cell based Biosystems written by Yi-Chen Ethan Li and published by CRC Press. This book was released on 2023-12-01 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cell science has emerged as a novel discipline in biomedical research over the past decade. With advancements in this field, stem cells have demonstrated versatile applications ranging from basic research to clinical case studies. Recognizing the demand for knowledge in stem cell applications, this book aims to provide comprehensive information on stem cell technology and its application in biosystems. It covers fundamental culture methods, advanced stem cell-based biosystems, and clinical case studies of stem cell therapy. This book is intended for individuals with an interest in stem cell science, offering valuable insights into this rapidly evolving field.

Download or read book Scientific Principles of Adipose Stem Cells written by Lauren Kokai and published by Academic Press. This book was released on 2021-08-19 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, ASCs for stem cell therapy and regenerative medicine, and ASCs in tissue engineering applications are also included. The book is written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and those seeking advanced information on adipose stem cells. - Coverage of basic adipose stem cell developmental biology (maturation process during embryogenesis) and mechanisms of regulating self-renewal and activation in the stem cell niche - Includes important methods for isolation and characterizing ASCs, as well as known data any impact of human demographics (age, sex, BMI) on ASC phenotype - An entire section dedicated to ASC biology, additional sections will be devoted to ASCs for stem cell therapy and regenerative medicine, as well as ASCs in tissue engineering applications

Download or read book Molecular Research on Dental Materials and Biomaterials 2018 written by Ihtesham Ur Rehman and published by MDPI. This book was released on 2021-04-21 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: The history of use of dental materials and biomaterial dates back to the BC era, but the real advances in this field have occurred since the 19th century, due to the invention and understanding of new materials. These advances have been due to the continuous quest for new materials and new technologies used for the design and fabrication of new and novel materials, and, in particular, the understanding of new materials with innovative clinical applications. These have only been possible due to interdisciplinary research of a translational nature, where physicians, surgeons, dentists, and materials scientists work together for a common and targeted goal. It is important for clinicians to understand the needs of the patient, who translates those needs for the materials scientist to develop an implant to improve the quality of life for the patient. Once the chemical, physical, mechanical, and biological properties of the materials are well understood, then these materials can be tailored to provide specific clinical applications. Development in the field of tissue engineering and regenerative medicine has only been possible due to work from this partnership. This Special Issue will provide an excellent forum to bring together different communities and publish research of a high caliber, which will be beneficial to healthcare.

Download or read book Dental Implants and Bone Grafts written by Hamdan Alghamdi and published by Woodhead Publishing. This book was released on 2019-08-30 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dental Implants and Bone Grafts: Materials and Biological Issues brings together cutting-edge research to provide detailed coverage of biomaterials for dental implants and bone graft, enabling scientists and clinicians to gain a thorough knowledge of advances and applications in this field. As tooth loss and alveolar bony defects are common and pose a significant health problem in dental clinics, this book deals with timely topics, including alveolar bone structures and pathological changes, reviews of indications and advantages of biomaterials for dental implants and bone graft, design and surface modification, biological interaction and biocompatibility of modern dental implants and bone graft, and new frontiers.This book is a highly valuable resource for scientists, clinicians and implantologists interested in biomaterial and regenerative strategies for alveolar bone reconstruction.

Download or read book Emerging Materials and Technologies for Bone Repair and Regeneration written by Ashok Kumar and published by CRC Press. This book was released on 2024-08-01 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers advancements in the field of bone repair and regeneration. It introduces bone development, repair, and regeneration and details different biomaterials and technologies involved in the fabrication and characterization of bone-related scaffolds and implants. The book explores nanotechnological intervention and folklore phytomedicines and their prospects in regenerating bone including major bone related disease conditions, infection, and their tackling via tissue engineering strategies. FEATURES: Covers polymer materials and technologies for bone repair and regeneration based on tissue engineering Defines the interdisciplinary mechanism of bone tissue repair ranging from the fields of material science, nanotechnology, and phytomedicine includes basic sciences, scaffolds, and bone infection Examines fabrication and characterization methods for the bone repair materials Reviews fundamentals of interlinked mechanisms of bone development, repair, and regeneration. This book is aimed at graduate students and researchers in biomedical and tissue engineering and biomaterial sciences.

Download or read book Recent Trends in Materials written by K. Geetha and published by Springer Nature. This book was released on 2022-10-31 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the select proceedings of 4th International Conference on Trends in Material Science and Inventive Materials (ICTMIM 2022). Various topics covered in this book are nanotechnology in materials science, green and sustainable materials, semiconductor & electronic materials and devices, bio electronic materials and sensors, thin films, materials surface and interfaces, modern electronic materials, multilayered structures and composite materials, quantum-sized structures and nanocrystals, electronic biosensors, MEMS and sensors, light emitting materials, nanomaterials, opto-electronic materials, microwave and antenna, nanostructure fabrication and self-assembly, self-healable and stretchable configurations, data-driven materials design, advanced charge transfer and suitable interfaces, metallization and superconductivity. Given the contents, the book will be useful for students, researchers and professionals working in the area of material science and engineering.

Download or read book 3D Printing for Tissue Engineering and Regenerative Medicine written by Murat Guvendiren and published by MDPI. This book was released on 2020-12-02 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three-dimensional (3D) printing enables the fabrication of tissue-engineered constructs and devices from a patient’s own medical data, leading to the creation of anatomically matched and patient-specific constructs. There is a growing interest in applying 3D printing technologies in the fields of tissue engineering and regenerative medicine. The main printing methods include extrusion-based, vat photopolymerization, droplet-based, and powder-based printing. A variety of materials have been used for printing, from metal alloys and ceramics to polymers and elastomers as well as from hydrogels to extracellular matrix proteins. More recently, bioprinting, a subcategory of 3D printing, has enabled the precise assembly of cell-laden biomaterials (i.e., bioinks) for the construction of complex 3D functional living tissues or artificial organs. In this Special Issue, we aim to capture state-of-the-art research papers and the most current review papers focusing on 3D printing for tissue engineering and regenerative medicine. In particular, we seek novel studies on the development of 3D printing and bioprinting approaches, developing printable materials (inks and bioinks), and utilizing 3D-printed scaffolds for tissue engineering and regenerative medicine applications. These applications are not limited to but include scaffolds for in vivo tissue regeneration and tissue analogues for in vitro disease modeling and/or drug screening.

Download or read book Functional Materials for Bio Applications written by Laura Maria Vergani and published by Frontiers Media SA. This book was released on 2020-12-15 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Download or read book Engineered Bone written by Herve Petite and published by CRC Press. This book was released on 2005-08-15 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses relevant issues that tissue-engineering researchers must consider when planning new strategies, especially in the bone and cartilage field. It describes transcription factors that are essential in bone development, and deals with bone healing.

Download or read book Bone Tissue Engineering written by Jeffrey O. Hollinger and published by CRC Press. This book was released on 2004-10-14 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t

Download or read book Calcium Orthophosphates written by Sergey V. Dorozhkin and published by CRC Press. This book was released on 2012-06-04 with total page 863 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium orthophospha

Download or read book Mesenchymal Stem Cell Therapy written by Lucas G. Chase and published by Springer Science & Business Media. This book was released on 2012-12-12 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Download or read book Human Stem Cell Manual written by Suzanne Peterson and published by Academic Press. This book was released on 2012-10-22 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual is a comprehensive compilation of "methods that work" for deriving, characterizing, and differentiating hPSCs, written by the researchers who developed and tested the methods and use them every day in their laboratories. The manual is much more than a collection of recipes; it is intended to spark the interest of scientists in areas of stem cell biology that they may not have considered to be important to their work. The second edition of the Human Stem Cell Manual is an extraordinary laboratory guide for both experienced stem cell researchers and those just beginning to use stem cells in their work. - Offers a comprehensive guide for medical and biology researchers who want to use stem cells for basic research, disease modeling, drug development, and cell therapy applications - Provides a cohesive global view of the current state of stem cell research, with chapters written by pioneering stem cell researchers in Asia, Europe, and North America - Includes new chapters devoted to recently developed methods, such as iPSC technology, written by the scientists who made these breakthroughs

Download or read book Nanotechnology for Bioengineers written by Wujie Zhang and published by Springer Nature. This book was released on 2022-05-31 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is an interdisciplinary field that is rapidly evolving and expanding. Significant advancements have been made in nanotechnology-related disciplines in the past few decades and continued growth and progression in the field are anticipated. Moreover, nanotechnology, omnipresent in innovation, has been applied to resolve critical challenges in nearly every field, especially those related to biological technologies and processes. This book, used as either a textbook for a short course or a reference book, provides state-of-the-art analysis of essential topics in nanotechnology for bioengineers studying and working in biotechnology, chemical/biochemical, pharmaceutical, biomedical, and other related fields. The book topics range from introduction to nanotechnology and nanofabrication to applications of nanotechnology in various biological fields. This book not only intends to introduce bioengineers to the amazing world of nanotechnology, but also inspires them to use nanotechnology to address some of the world's biggest challenges.

Download or read book Bone Biology Harvesting Grafting for Dental Implants written by Arun K. Garg and published by Quintessence Publishing (IL). This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses all aspects of dental implants offering an overview of bone biology. Reviews graft materials and membrane barriers as well as recommends the situations and types of defects for which these materials are best suited. Covers harvesting and surgical techniques. Abundant color illustrations.

Download or read book Human Neural Stem Cells written by Leonora Buzanska and published by Springer. This book was released on 2018-09-12 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing. The powerful potential of hNSC to generate and repair the developing and adult CNS has been confirmed by numerous experimental in vitro and in vivo studies. The book presents methods for hNSC derivation and discusses the mechanisms underlying NSC in vitro fate decisions and their in vivo therapeutic mode of action. The long-standing dogma that the human central nervous system (CNS) lacks the ability to regenerate was refuted at the end of the 20th century, when evidence of the presence of neurogenic zones in the adult human brain was found. These neurogenic zones are home to human neural stem cells (hNSCs), which are capable of self-renewing and differentiating into neurons, astrocytes and oligodendrocytes. NSCs isolated from human CNS have a number of clinical advantages, especially the innate potential to differentiate into functional neural cells. Nevertheless, their full clinical exploitation has been hindered by limited access to the tissue and low expansion potential. The search for an alternative to CNS sources of autologous, therapeutically competent hNSCs was the driving force for the many studies proving the in vitro plasticity of different somatic stem cells to generate NSCs and their functional progeny. Now the era of induced pluripotent stem cells has opened entirely new opportunities to achieve research and therapeutic goals with the aid of hNSCs.