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Book Osteoblasts Response to Anodized Commercially Pure Titanium in Vitro

Download or read book Osteoblasts Response to Anodized Commercially Pure Titanium in Vitro written by Jun Chen and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book In Vitro Osteoblast Responses to CpTi and Ti 6Al 4V Alloy

Download or read book In Vitro Osteoblast Responses to CpTi and Ti 6Al 4V Alloy written by RA. Draughn and published by . This book was released on 1996 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: Commercially pure Ti and Ti-6Al-4V have been widely used as dental implant materials. Several reports have demonstrated that there are subtle differences in the nature of the oxide between these two materials which may have important biological consequences. An earlier report by our group demonstrated differences in oxide chemistry between cpTi and Ti alloy does not affect short term in vitro responses of osteoblast cultures. In this work, long term phenotypic expression of typical bone cell markers such as osteocalcin and alkaline phosphatase were not different between metal or control surfaces. There was a slight difference in total Ca+2 per culture for alloy compared to cpTi, however, these differences were not statistically different. Based on this work, both cpTi and Ti alloy surfaces support in vitro biological mineralization and are in general agreement with in vivo findings.

Book Advanced Surfaces for Stem Cell Research

Download or read book Advanced Surfaces for Stem Cell Research written by Ashutosh Tiwari and published by John Wiley & Sons. This book was released on 2016-11-29 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book outlines first the importance of Extra Cellular Matrix (ECM), which is a natural surface for most of cells. In the following chapters the influence of biological, chemical, mechanical, and physical properties of surfaces in micro and nano-scale on stem cell behavior are discussed including the mechanotransduction. Biomimetic and bioinspired approaches are highlighted for developing microenvironment of several tissues, and surface engineering applications are discussed in tissue engineering, regenerative medicine and different type of biomaterials in various chapters of the book. This book brings together innovative methodologies and strategies adopted in the research and development of Advanced Surfaces in Stem Cell Research. Well-known worldwide researchers deliberate subjects including: Extracellular matrix proteins for stem cell fate The superficial mechanical and physical properties of matrix microenvironment as stem cell fate regulator Effects of mechanotransduction on stem cell behavior Modulation of stem cells behavior through bioactive surfaces Influence of controlled micro and nanoengineered surfaces on stem cell fate Nanostructured polymeric surfaces for stem cells Laser surface modification techniques and stem cells applications Plasma polymer deposition: a versatile tool for stem cell research Application of bioreactor concept and modeling techniques in bone regeneration and augmentation treatments Substrates and surfaces for control of pluripotent stem cell fate and function Application of biopolymer-based, surface modified devices in transplant medicine and tissue engineering Silk as a natural biopolymer for tissue engineering

Book The Effect of Pure Titanium and Titanium Alloy on Osteoblast and Chondrocyte Maturatin In Vitro

Download or read book The Effect of Pure Titanium and Titanium Alloy on Osteoblast and Chondrocyte Maturatin In Vitro written by Jack Lincks and published by . This book was released on 1999 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implant success is dependent on the interaction of the implant with surrounding tissues. By understanding this, better devices can be developed. Substrate specific information regarding implant surface characteristics and its influence on mesenchymal cell proliferation and differentiation may be helpful in the design of implants to optimize bone growth at the interface. Based on in vivo and in vitro studies, biomaterial composition, surface energy, surface roughness, and surface topography appear to play a major role in implant success. However, in-depth analysis of cellular response to various implant surface characteristics and the ensuing local and systemic factor production remain to be performed. The first aim of this study was to evaluate the ability of two implant characteristics, chemical composition and surface roughness, to modulate various parameters of osteoblast metabolism in vitro. Commercially pure titanium (Ti) and titanium-6 wt.% aluminum-4 wt.% vanadium alloy (Ti-A) disks were machined to achieve a specific roughness through either fine-polishing (S, smooth, Ra 0.2 micronmeter) or wet sand-grinding (R, rough, Ra 3.0 micronmeter). Profilometry and scanning electron microscopy (SEM) were used to determine surface roughness, Auger spectroscopy and FT-IR were also used to characterize the disks. MG63 osteoblast-like human osteosarcoma cells were seeded at 9300 cells/cm2 and cultured to confluence on standard tissue culture polystyrene or the Ti surfaces. Cell morphology was assessed by SEM. Osteoblast cultures were examined for differences in proliferation as measured by cell number, and 3H-thymidine incorporation; differentiation by cell and cell layer alkaline phosphatase specific activity (ALpase) and osteocalcin production; matrix synthesis by proteoglycan sulfation and % collagen production; and cytokine production by transforming growth factor-Beta and prostaglandin E2 production.

Book The Effect of Plasma Treatment of the Surface of Commercially Pure Titanium on the Degree of Cellular Spreading of Osteoblasts

Download or read book The Effect of Plasma Treatment of the Surface of Commercially Pure Titanium on the Degree of Cellular Spreading of Osteoblasts written by John Peter Joseph Fearon and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book VI Latin American Congress on Biomedical Engineering CLAIB 2014 Paran Argentina 29 30 31 October 2014

Download or read book VI Latin American Congress on Biomedical Engineering CLAIB 2014 Paran Argentina 29 30 31 October 2014 written by Ariel Braidot and published by Springer. This book was released on 2015-03-13 with total page 1050 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the proceedings of the CLAIB 2014, held in Paraná, Entre Ríos, Argentina 29, 30 & 31 October 2014. The proceedings, presented by the Regional Council of Biomedical Engineering for Latin America (CORAL) offer research findings, experiences and activities between institutions and universities to develop Bioengineering, Biomedical Engineering and related sciences. The conferences of the American Congress of Biomedical Engineering are sponsored by the International Federation for Medical and Biological Engineering (IFMBE), Society for Engineering in Biology and Medicine (EMBS) and the Pan American Health Organization (PAHO), among other organizations and international agencies and bringing together scientists, academics and biomedical engineers in Latin America and other continents in an environment conducive to exchange and professional growth. The Topics include: - Bioinformatics and Computational Biology - Bioinstrumentation; Sensors, Micro and Nano Technologies - Biomaterials, Tissue Engineering and Artificial Organs - Biomechanics, Robotics and Motion Analysis - Biomedical Images and Image Processing - Biomedical Signal Processing - Clinical Engineering and Electromedicine - Computer and Medical Informatics - Health and home care, telemedicine - Modeling and Simulation - Radiobiology, Radiation and Medical Physics - Rehabilitation Engineering and Prosthetics - Technology, Education and Innovation

Book Induction of Bone Resorbing Agents by Titanium Particulates

Download or read book Induction of Bone Resorbing Agents by Titanium Particulates written by TT. Glant and published by . This book was released on 1996 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although titanium and titanium alloys demonstrate excellent biocompatability in bulk form, titanium in particulate form can provoke a variety of cellular responses. In this series of experiments, we have shown that commercially pure titanium particulates of phagocytosable size stimulate the secretion of mediators of bone resorption (prostaglandin E2 and interleukin-1) from macrophages and cause bone resorption in organ culture. In addition, we have shown that phagocytosable titanium particles stimulate fibroblasts to up regulate the expression of matrix metalloproteinases (stromelysin and collagenase) without a substantial effect on the tissue inhibitor of these enzymes (TIMP). Titanium particulates also have a suppressive effect on procollagen synthesis by an osteoblast-like cell line. Thus, titanium particulates have the capacity to stimulate bone resorption and inhibit bone matrix formation.

Book Effect of Anodized and Hydrothermal treated Titanium Implant Surfaces on Osteoblast Precursor Cell Response

Download or read book Effect of Anodized and Hydrothermal treated Titanium Implant Surfaces on Osteoblast Precursor Cell Response written by Raymond Michael Rodriguez and published by . This book was released on 2003 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Anodized Titania Processing and Characterization to Improve Cell materials Interactions for Load Bearing Implants

Download or read book Anodized Titania Processing and Characterization to Improve Cell materials Interactions for Load Bearing Implants written by Kakoli Das and published by . This book was released on 2007 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this study is to investigate in vitro cell-materials interactions using human osteoblast cells on anodized titanium. Titanium is a bioinert material and, therefore, gets encapsulated after implantation into the living body by a fibrous tissue that isolates them from the surrounding tissues. In this work, bioactive nonporous and nanoporous TiO2 layers were grown on commercially pure titanium substrate by anodization process using different electrolyte solutions namely (1) H3PO 4, (2) HF and (3) H2SO4, (4) aqueous solution of citric acid, sodium fluoride and sulfuric acid. The first three electrolytes produced bioactive TiO2 films with a nonporous structure showing three distinctive surface morphologies. Nanoporous morphology was obtained on Ti-surfaces from the fourth electrolyte at 20V for 4h. Cross-sectional view of the nanoporous surface reveals titania nanotubes of length 600 nm. It was found that increasing anodization time initially increased the height of the nanotubes while maintaining the tubular array structure, but beyond 4h, growth of nanotubes decreased with a collapsed array structure. Human osteoblast (HOB) cell attachment and growth behavior were studied using an osteoprecursor cell line (OPC 1) for 3, 7 and 11 days. Colonization of the cells was noticed with distinctive cell-to-cell attachment on HF anodized surfaces. TiO2 layer grown in H2SO4 electrolyte did not show significant cell growth on the surface, and some cell death was also noticed. Good cellular adherence with extracellular matrix extensions in between the cells was noticed for samples anodized with H3PO 4 electrolyte and nanotube surface. Cell proliferation was excellent on anodized nanotube surfaces. An abundant amount of extracellular matrix (ECM) between the neighboring cells was also noticed on nanotube surfaces with filopodia extensions coming out from cells to grasp the nanoporous surface for anchorage. To better understand and compare cell-materials interactions, anodized nanoporous sample surfaces were etched with different patterns. Preferential cell attachment was noticed on nanotube surfaces compared to no cells on etched patterned surface. Cell adhesions and differentiation were more pronounced with vinculin protein and alkaline phosphatase, respectively, on anodized surfaces. MTT assays showed increase in living cell density and higher proliferation on H3PO4, HF and nanotube surfaces. When anodized surfaces were compared for cell materials interaction, it was noticed that each of the surfaces has different surface properties that led to variations in cell-materials interactions. It was clear that rough surface morphology, high surface energy, and low value of the contact angles were important factors for better cell materials interaction. Mineralization study was done in simulated body fluid (SBF) with ion concentration nearly equal to human blood plasma to further understand biomimetic apatite deposition behavior. Similar to cell-materials interaction, variation in mineral deposition behavior was also noticed for films grown with different electrolytes. These results clearly show that nonporous titania in H3PO4, HF electrolytes and nanotubes can significantly increase biocompatibility of Ti implants, which has the potential to reduce the healing time and increase in vivo lifetime for these implants.

Book Advances in Staphylococcaceae Research and Application 2012 Edition

Download or read book Advances in Staphylococcaceae Research and Application 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Staphylococcaceae Research and Application / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Staphylococcaceae in a concise format. The editors have built Advances in Staphylococcaceae Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Staphylococcaceae in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Staphylococcaceae Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Book Comprehensive Biomaterials II

Download or read book Comprehensive Biomaterials II written by Kevin Healy and published by Elsevier. This book was released on 2017-05-18 with total page 4865 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications

Book Bioscience and Bioengineering of Titanium Materials

Download or read book Bioscience and Bioengineering of Titanium Materials written by Yoshiki Oshida and published by Elsevier. This book was released on 2010-07-07 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book about bioscience and the bioengineering of titanium materials is based on more than 1,000 published articles. It bridges the gap between the medical/dental fields and the engineering/technology areas, due to the author’s unique experience in both during the last 30 years. The book covers Materials Classifications, Chemical and Electrochemical Reactions, Oxidation, Biological Reactions, Implant-related Biological Reactions, Applications, Fabri-cation Technologies, Surface Modifications, and Future Perspectives. * Provides quick access to the primary literature in this field* Reviews studies of titanium materials in medical and dental applications, as reported in nearly 1,500 articles published over last several years* Draws information from several types of studies and reports* Helps readers answer questions about the most appropriate materials and when to use them

Book Surface Engineering and Technology for Biomedical Implants

Download or read book Surface Engineering and Technology for Biomedical Implants written by Yoshiki Oshida and published by Momentum Press. This book was released on 2014-04-15 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new book synthesizes a wide range of interdisciplinary literature to provide the state-of-the art of biomedical implants. It discusses materials and explains the three basic requirements for implant success from a surface engineering perspective: biological compatibility, biomechanical compatibility, morphological compatibility. Biomedical, mechanical, and materials engineers will find this book indispensable for understanding proper treatment of implant surfaces in order to achieve clinical success. Highlights include: • Coverage of surface engineering of polymer, metallic, ceramic and composite implant materials; • Coverage of chemical, mechanical, physical, thermal, and combined surface modification technologies; • Explanations of interfacial reaction between vital tissue and non-vital implant surface; and • Methodologies and technologies for modification of surface layer/zone to promote the osteo-integration, the ultimate success for biomedical implants in both dental and medical practice.