Download or read book Biological Clocks Rhythms and Oscillations written by Daniel B. Forger and published by MIT Press. This book was released on 2024-08-06 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the mathematical, computational, and analytical techniques used for modeling biological rhythms, presenting tools from many disciplines and example applications. All areas of biology and medicine contain rhythms, and these behaviors are best understood through mathematical tools and techniques. This book offers a survey of mathematical, computational, and analytical techniques used for modeling biological rhythms, gathering these methods for the first time in one volume. Drawing on material from such disciplines as mathematical biology, nonlinear dynamics, physics, statistics, and engineering, it presents practical advice and techniques for studying biological rhythms, with a common language. The chapters proceed with increasing mathematical abstraction. Part I, on models, highlights the implicit assumptions and common pitfalls of modeling, and is accessible to readers with basic knowledge of differential equations and linear algebra. Part II, on behaviors, focuses on simpler models, describing common properties of biological rhythms that range from the firing properties of squid giant axon to human circadian rhythms. Part III, on mathematical techniques, guides readers who have specific models or goals in mind. Sections on “frontiers” present the latest research; “theory” sections present interesting mathematical results using more accessible approaches than can be found elsewhere. Each chapter offers exercises. Commented MATLAB code is provided to help readers get practical experience. The book, by an expert in the field, can be used as a textbook for undergraduate courses in mathematical biology or graduate courses in modeling biological rhythms and as a reference for researchers.
Download or read book Introduction to Mathematical Biology written by Ching Shan Chou and published by Springer. This book was released on 2016-04-27 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on a one semester course that the authors have been teaching for several years, and includes two sets of case studies. The first includes chemostat models, predator-prey interaction, competition among species, the spread of infectious diseases, and oscillations arising from bifurcations. In developing these topics, readers will also be introduced to the basic theory of ordinary differential equations, and how to work with MATLAB without having any prior programming experience. The second set of case studies were adapted from recent and current research papers to the level of the students. Topics have been selected based on public health interest. This includes the risk of atherosclerosis associated with high cholesterol levels, cancer and immune interactions, cancer therapy, and tuberculosis. Readers will experience how mathematical models and their numerical simulations can provide explanations that guide biological and biomedical research. Considered to be the undergraduate companion to the more advanced book "Mathematical Modeling of Biological Processes" (A. Friedman, C.-Y. Kao, Springer – 2014), this book is geared towards undergraduate students with little background in mathematics and no biological background.
Download or read book Parabolic Equations in Biology written by Benoît Perthame and published by Springer. This book was released on 2015-09-09 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents several fundamental questions in mathematical biology such as Turing instability, pattern formation, reaction-diffusion systems, invasion waves and Fokker-Planck equations. These are classical modeling tools for mathematical biology with applications to ecology and population dynamics, the neurosciences, enzymatic reactions, chemotaxis, invasion waves etc. The book presents these aspects from a mathematical perspective, with the aim of identifying those qualitative properties of the models that are relevant for biological applications. To do so, it uncovers the mechanisms at work behind Turing instability, pattern formation and invasion waves. This involves several mathematical tools, such as stability and instability analysis, blow-up in finite time, asymptotic methods and relative entropy properties. Given the content presented, the book is well suited as a textbook for master-level coursework.
Download or read book Topics in Mathematical Biology written by Karl Peter Hadeler and published by Springer. This book was released on 2017-12-20 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book analyzes the impact of quiescent phases on biological models. Quiescence arises, for example, when moving individuals stop moving, hunting predators take a rest, infected individuals are isolated, or cells enter the quiescent compartment of the cell cycle. In the first chapter of Topics in Mathematical Biology general principles about coupled and quiescent systems are derived, including results on shrinking periodic orbits and stabilization of oscillations via quiescence. In subsequent chapters classical biological models are presented in detail and challenged by the introduction of quiescence. These models include delay equations, demographic models, age structured models, Lotka-Volterra systems, replicator systems, genetic models, game theory, Nash equilibria, evolutionary stable strategies, ecological models, epidemiological models, random walks and reaction-diffusion models. In each case we find new and interesting results such as stability of fixed points and/or periodic orbits, excitability of steady states, epidemic outbreaks, survival of the fittest, and speeds of invading fronts. The textbook is intended for graduate students and researchers in mathematical biology who have a solid background in linear algebra, differential equations and dynamical systems. Readers can find gems of unexpected beauty within these pages, and those who knew K.P. (as he was often called) well will likely feel his presence and hear him speaking to them as they read.
Download or read book Stability and Oscillations in Delay Differential Equations of Population Dynamics written by K. Gopalsamy and published by Springer Science & Business Media. This book was released on 1992-03-31 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph provides a definitive overview of recent advances in the stability and oscillation of autonomous delay differential equations. Topics include linear and nonlinear delay and integrodifferential equations, which have potential applications to both biological and physical dynamic processes. Chapter 1 deals with an analysis of the dynamical characteristics of the delay logistic equation, and a number of techniques and results relating to stability, oscillation and comparison of scalar delay and integrodifferential equations are presented. Chapter 2 provides a tutorial-style introduction to the study of delay-induced Hopf bifurcation to periodicity and the related computations for the analysis of the stability of bifurcating periodic solutions. Chapter 3 is devoted to local analyses of nonlinear model systems and discusses many methods applicable to linear equations and their perturbations. Chapter 4 considers global convergence to equilibrium states of nonlinear systems, and includes oscillations of nonlinear systems about their equilibria. Qualitative analyses of both competitive and cooperative systems with time delays feature in both Chapters 3 and 4. Finally, Chapter 5 deals with recent developments in models of neutral differential equations and their applications to population dynamics. Each chapter concludes with a number of exercises and the overall exposition recommends this volume as a good supplementary text for graduate courses. For mathematicians whose work involves functional differential equations, and whose interest extends beyond the boundaries of linear stability analysis.
Download or read book Mathematical Models in Biology written by Leah Edelstein-Keshet and published by SIAM. This book was released on 1988-01-01 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Models in Biology is an introductory book for readers interested in biological applications of mathematics and modeling in biology. A favorite in the mathematical biology community, it shows how relatively simple mathematics can be applied to a variety of models to draw interesting conclusions. Connections are made between diverse biological examples linked by common mathematical themes. A variety of discrete and continuous ordinary and partial differential equation models are explored. Although great advances have taken place in many of the topics covered, the simple lessons contained in this book are still important and informative. Audience: the book does not assume too much background knowledge--essentially some calculus and high-school algebra. It was originally written with third- and fourth-year undergraduate mathematical-biology majors in mind; however, it was picked up by beginning graduate students as well as researchers in math (and some in biology) who wanted to learn about this field.
Download or read book Oscillation Theory for Neutral Differential Equations with Delay written by D.D Bainov and published by CRC Press. This book was released on 1991-01-01 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: With neutral differential equations, any lack of smoothness in initial conditions is not damped and so they have proven to be difficult to solve. Until now, there has been little information to help with this problem. Oscillation Theory for Neutral Differential Equations with Delay fills a vacuum in qualitative theory of functional differential equations of neutral type. With much of the presented material previously unavailable outside Eastern Europe, this authoritative book provides a stimulus to research the oscillatory and asymptotic properties of these equations. It examines equations of first, second, and higher orders as well as the asymptotic behavior for tending toward infinity. These results are then generalized for partial differential equations of neutral type. The book also describes the historical development of the field and discusses applications in mathematical models of processes and phenomena in physics, electrical control and engineering, physical chemistry, and mathematical biology. This book is an important tool not only for mathematicians, but also for specialists in many fields including physicists, engineers, and biologists. It may be used as a graduate-level textbook or as a reference book for a wide range of subjects, from radiophysics to electrical and control engineering to biological science.
Download or read book Essential Mathematical Biology written by Nicholas F. Britton and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This self-contained introduction to the fast-growing field of Mathematical Biology is written for students with a mathematical background. It sets the subject in a historical context and guides the reader towards questions of current research interest. A broad range of topics is covered including: Population dynamics, Infectious diseases, Population genetics and evolution, Dispersal, Molecular and cellular biology, Pattern formation, and Cancer modelling. Particular attention is paid to situations where the simple assumptions of homogenity made in early models break down and the process of mathematical modelling is seen in action.
Download or read book Computational Cell Biology written by Christopher P. Fall and published by Springer Science & Business Media. This book was released on 2007-06-04 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an introduction to dynamic modeling in molecular cell biology, taking a computational and intuitive approach. Detailed illustrations, examples, and exercises are included throughout the text. Appendices containing mathematical and computational techniques are provided as a reference tool.
Download or read book Mathematical Biology written by James D. Murray and published by Springer Science & Business Media. This book was released on 2007-06-12 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Biology is a richly illustrated textbook in an exciting and fast growing field. Providing an in-depth look at the practical use of math modeling, it features exercises throughout that are drawn from a variety of bioscientific disciplines - population biology, developmental biology, physiology, epidemiology, and evolution, among others. It maintains a consistent level throughout so that graduate students can use it to gain a foothold into this dynamic research area.
Download or read book Mathematical Methods for Oscillations and Waves written by Joel Franklin and published by Cambridge University Press. This book was released on 2020-03-05 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anchored in simple and familiar physics problems, the author provides a focused introduction to mathematical methods in a narrative driven and structured manner. Ordinary and partial differential equation solving, linear algebra, vector calculus, complex variables and numerical methods are all introduced and bear relevance to a wide range of physical problems. Expanded and novel applications of these methods highlight their utility in less familiar areas, and advertise those areas that will become more important as students continue. This highlights both the utility of each method in progressing with problems of increasing complexity while also allowing students to see how a simplified problem becomes 're-complexified'. Advanced topics include nonlinear partial differential equations, and relativistic and quantum mechanical variants of problems like the harmonic oscillator. Physics, mathematics and engineering students will find 300 problems treated in a sophisticated manner. The insights emerging from Franklin's treatment make it a valuable teaching resource.
Download or read book Nonlinear Oscillations and Waves in Dynamical Systems written by P.S Landa and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: A rich variety of books devoted to dynamical chaos, solitons, self-organization has appeared in recent years. These problems were all considered independently of one another. Therefore many of readers of these books do not suspect that the problems discussed are divisions of a great generalizing science - the theory of oscillations and waves. This science is not some branch of physics or mechanics, it is a science in its own right. It is in some sense a meta-science. In this respect the theory of oscillations and waves is closest to mathematics. In this book we call the reader's attention to the present-day theory of non-linear oscillations and waves. Oscillatory and wave processes in the systems of diversified physical natures, both periodic and chaotic, are considered from a unified poin t of view . The relation between the theory of oscillations and waves, non-linear dynamics and synergetics is discussed. One of the purposes of this book is to convince reader of the necessity of a thorough study popular branches of of the theory of oscillat ions and waves, and to show that such science as non-linear dynamics, synergetics, soliton theory, and so on, are, in fact , constituent parts of this theory. The primary audiences for this book are researchers having to do with oscillatory and wave processes, and both students and post-graduate students interested in a deep study of the general laws and applications of the theory of oscillations and waves.
Download or read book Oscillations in Mathematical Biology written by J.P.E. Hodgson and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: The papers in this volume are based on talks given at a one day conference held on the campus of Adelphi University in April 1982. The conference was organized with the title "Oscillations in Mathematical Biology;" however the speakers were allowed considerable latitutde in their choice of topics. In the event, the talks all concerned the dynamics of non-linear systems arising in biology so that the conference achieved a good measure of cohesion. Some of the speakers cho~e not to submit a manuscript for these proceedings, feeling that their material was too conjectural to be committed to print. Also the paper of Rinzel and Troy is a distillation of the two separate talks that the authors gave. Otherwise the material reproduces the conference proceedings. The conference was made possible by the generous support of the Office of the Dean of the College of Arts and Sciences at Adelphi. The bulk of the organization of the conference was carried out by Dr. Ronald Grisell whose energy was in large measure responsible for the success of the conference.
Download or read book Mathematical Biology written by James D. Murray and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical biology - the use of mathematical ideas and models in the biosciences - is a fast growing, very exciting and increasingly important inderdisciplinary field. This textbook is an account of some of the major techniques and models used and of some genuine practical applications drawn from current areas of research interest in, for example, population ecology, developmental biology, physiology, epidemiology and evolution. It provides the reader with a thorough background, sufficient to start genuine interdisciplinary collaborative reserach with biomedical scientists.
Download or read book Mathematical Models for Biological Pattern Formation written by Philip K. Maini and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 121st IMA volume, entitled MATHEMATICAL MODELS FOR BIOLOGICAL PATTERN FORMATION is the first of a new series called FRONTIERS IN APPLICATION OF MATHEMATICS. The FRONTIERS volumes are motivated by IMA pro grams and workshops, but are specially planned and written to provide an entree to and assessment of exciting new areas for the application of mathematical tools and analysis. The emphasis in FRONTIERS volumes is on surveys, exposition and outlook, to attract more mathematicians and other scientists to the study of these areas and to focus efforts on the most important issues, rather than papers on the most recent research results aimed at an audience of specialists. The present volume of peer-reviewed papers grew out of the 1998-99 IMA program on "Mathematics in Biology," in particular the Fall 1998 em phasis on "Theoretical Problems in Developmental Biology and Immunol ogy." During that period there were two workshops on Pattern Formation and Morphogenesis, organized by Professors Murray, Maini and Othmer. James Murray was one of the principal organizers for the entire year pro gram. I am very grateful to James Murray for providing an introduction, and to Philip Maini and Hans Othmer for their excellent work in planning and preparing this first FRONTIERS volume. I also take this opportunity to thank the National Science Foundation, whose financial support of the IMA made the Mathematics in Biology pro gram possible.
Download or read book Mathematical Modeling of Biological Processes written by Avner Friedman and published by Springer. This book was released on 2014-09-19 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on mathematical modeling of biological processes includes a wide selection of biological topics that demonstrate the power of mathematics and computational codes in setting up biological processes with a rigorous and predictive framework. Topics include: enzyme dynamics, spread of disease, harvesting bacteria, competition among live species, neuronal oscillations, transport of neurofilaments in axon, cancer and cancer therapy, and granulomas. Complete with a description of the biological background and biological question that requires the use of mathematics, this book is developed for graduate students and advanced undergraduate students with only basic knowledge of ordinary differential equations and partial differential equations; background in biology is not required. Students will gain knowledge on how to program with MATLAB without previous programming experience and how to use codes in order to test biological hypothesis.
Download or read book Nonoscillation and Oscillation Theory for Functional Differential Equations written by Ravi P. Agarwal and published by CRC Press. This book was released on 2004-08-30 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the qualitative theory of differential equations with or without delays, collecting recent oscillation studies important to applications and further developments in mathematics, physics, engineering, and biology. The authors address oscillatory and nonoscillatory properties of first-order delay and neutral delay differential eq
