Download or read book Origins of Resistance to Toxic Agents written by M Sevag and published by Academic Press. This book was released on 2012-12-02 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Origins of Resistance to Toxic Agents contains the proceedings of the Symposium held in Washington, D.C. on March 25-27, 1954. Contributors theoretically explore the origins of drug resistance and related problems, based on the concept that the development of resistance to various toxic agents is associated with alterations and/or loss in enzyme proteins, and can explain the mutational and other processes. This text is organized into five sections encompassing 25 chapters and begins with an overview of the evolutionary aspects of resistance to antibacterial agents, herbicides, and insecticides. The book then discusses spontaneous and induced mutations to drug resistance in Escherichia coli, along with the mechanism of drug resistance in protozoa and bacteria, the physiological aspects of insect resistance to insecticides, and the enzymatic detoxication of DDT. The next chapters focus on the origins of tolerance and addiction to drugs and the problem of alcoholism; biochemical effects of narcotics and alcohol administration; tolerance and physical dependence to narcotics; and resistance and dependence in cancer cells. The book concludes by analyzing the significance of protein configuration to the specificity of biological interaction. This book is a valuable source of information for physicians, biochemists, pharmacologists, entomologists, plant physiologists, students of cancer, and those who are interested in the theory of the evolution of living matter.
Download or read book Origins of Resistance to Toxic Agents written by United States. Office of Naval Research and published by . This book was released on 1955 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book ORIGINS OF RESISTANCE TO TOXIC AGENTS PROCEEDINGS OF A SYMPOSIUM written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms of antibiotic resistance written by Jun Lin and published by Frontiers Media SA. This book was released on 2015-06-01 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
Download or read book Microbial Evolution and Co Adaptation written by Institute of Medicine and published by National Academies Press. This book was released on 2009-05-10 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.
Download or read book Antibiotic Resistance written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotic Resistance: Origins, Evolution, Selection and Spread Chairman: Stuart B. Levy, 1997 Over the last 50 years, the rapid increase in the use of antibiotics, not only in people, but also in animal husbandry and agriculture, has delivered a selection unprecedented in the history of evolution. Consequently, society is facing one of its gravest public health problems-the emergence of infectious bacteria with resistance to many, and in some cases all, available antibiotics. This book brings together a multidisciplinary group of experts to discuss this problem. It begins by examining the origins of resistance and goes on to look at how the use of antibiotics in human medicine and farming/agriculture has selected for resistant bacteria. Separate chapters describe the evolution of resistance determinants and how these are spread both within and between bacterial species. Finally, the book contains discussions on strategies for countering the threat of antibiotic resistance. A major re-thinking of our approach to the treatment of infectious diseases is proposed-that antibiotic resistance should be seen as a problem created by the disruption of normal microbial ecology. To restore efficacy to earlier antibiotics, and to maintain the success of new antibiotics that are introduced, we need to use these drugs in a way that ensures an ecological balance that favours the predominance of susceptible bacteria.
Download or read book Antimicrobial Drug Resistance written by Douglas L. Mayers and published by Springer. This book was released on 2017-07-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two volumes included in Antimicrobial Drug Resistance, Second Edition is an updated, comprehensive and multidisciplinary reference covering the area of antimicrobial drug resistance in bacteria, fungi, viruses, and parasites from basic science, clinical, and epidemiological perspectives. This newly revised compendium reviews the most current research and development on drug resistance while still providing the information in the accessible format of the first edition. The first volume, Antimicrobial Drug Resistance: Mechanisms of Drug Resistance, is dedicated to the biological basis of drug resistance and effective avenues for drug development. With the emergence of more drug-resistant organisms, the approach to dealing with the drug resistance problem must include the research of different aspects of the mechanisms of bacterial resistance and the dissemination of resistance genes as well as research utilizing new genomic information. These approaches will permit the design of novel strategies to develop new antibiotics and preserve the effectiveness of those currently available. The second volume, Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects, is devoted to the clinical aspects of drug resistance. Although there is evidence that restricted use of a specific antibiotic can be followed by a decrease in drug resistance to that agent, drug resistance control is not easily achieved. Thus, the infectious diseases physician requires input from the clinical microbiologist, antimicrobial stewardship personnel, and infection control specialist to make informed choices for the effective management of various strains of drug-resistant pathogens in individual patients. This 2-volume set is an important reference for students in microbiology, infectious diseases physicians, medical students, basic scientists, drug development researchers, microbiologists, epidemiologists, and public health practitioners.
Download or read book U S Office of Naval Research Origins of Resistance to Toxic Agents written by M. G. Sevag and published by . This book was released on 1955 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Effects on Human Health of Subtherapeutic Use of Antimicrobials in Animal Feeds written by National Research Council and published by National Academies Press. This book was released on 1980-02-01 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Treating Infectious Diseases in a Microbial World written by National Research Council and published by National Academies Press. This book was released on 2006-01-03 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Download or read book Poisonous Plants and Phytochemicals in Drug Discovery written by Andrew G. Mtewa and published by John Wiley & Sons. This book was released on 2020-12-22 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career
Download or read book A Short History of Biological Warfare written by W. Seth Carus and published by Government Printing Office. This book was released on 2017-08-03 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication gives a history of biological warfare (BW) from the prehistoric period through the present, with a section on the future of BW. The publication relies on works by historians who used primary sources dealing with BW. In-depth definitions of biological agents, biological weapons, and biological warfare (BW) are included, as well as an appendix of further reading on the subject. Related items: Arms & Weapons publications can be found here: https://bookstore.gpo.gov/catalog/arms-weapons Hazardous Materials (HAZMAT & CBRNE) publications can be found here: https://bookstore.gpo.gov/catalog/hazardous-materials-hazmat-cbrne
Download or read book Silent Spring written by Rachel Carson and published by Houghton Mifflin Harcourt. This book was released on 2002 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essential, cornerstone book of modern environmentalism is now offered in a handsome 40th anniversary edition which features a new Introduction by activist Terry Tempest Williams and a new Afterword by Carson biographer Linda Lear.
Download or read book Antimicrobial Resistance written by World Health Organization and published by . This book was released on 2014 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.
Download or read book Toxic written by Dan Kaszeta and published by Oxford University Press, USA. This book was released on 2021-03 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nerve agents are the world's deadliest means of chemical warfare. Nazi Germany developed the first military-grade nerve agents and massive industry for their manufacture--yet, strangely, the Third Reich never used them. At the end of the Second World War, the Allies were stunned to discover this advanced and extensive programme. The Soviets and Western powers embarked on a new arms race, amassing huge chemical arsenals. From their Nazi invention to the 2018 Novichok attack in Britain, Dan Kaszeta uncovers nerve agents' gradual spread across the world, despite international arms control efforts. They've been deployed in the Iran-Iraq War, by terrorists in Japan, in the Syrian Civil War, and by assassins in Malaysia and Salisbury--always with bitter consequences. Toxic recounts the grisly history of these weapons of mass destruction: a deadly suite of invisible, odourless killers.
Download or read book Bovine Science written by Sadashiv S. O. and published by BoD – Books on Demand. This book was released on 2019-02-27 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the beginning of civilization, humans and animals have developed very strong associations to their mutual benefits. Livestock, particularly bovines, are important contributors to total food production in the world. The social expectations in Science and Technology are increasing because of rapid advances. Prevention and control of infectious diseases in bovines have been among the top-most public health objective in the last decade. In the present book, experts from different continents present important aspects of bovine science such as louse infestations of ruminants, cytogenetics of bovines, factors of competitiveness for bovines, feed manipulation, enhancement of conjugated linoleic acid and its bioavailability, emergence of antimicrobial resistance, and also meat quality. The aim of this book to provide an understanding of the present scenario, advances and challenges in bovine science.
Download or read book Antibiotic Resistance in the Environment written by Célia M. Manaia and published by Springer. This book was released on 2021-08-22 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a multidisciplinary review of antibiotic resistance and unravels the complex and interrelated roles of environmental sources, including pharmaceutical industry effluents, hospital and domestic effluents, wildlife and drinking water. Antibiotic resistance is a global public health issue in which the interface between humans, animals and the environment is particularly relevant. The contrasts seen across different environmental compartments and world regions, which are due to climate, social and policy differences, mean that this problem needs to be analyzed from a multi-geographic and multi-cultural angle. Bringing together contributions from researchers on different continents with expertise in antibiotic resistance in a range of different environmental compartments, the book offers a detailed reflection on the paths that make antibiotic resistance a global threat, and the state-of- the-art in antibiotic resistance surveillance and risk assessment in complex environmental matrices.
