Download or read book Natural Production of Organohalogen Compounds written by Gordon W. Gribble and published by Springer. This book was released on 2005-07-25 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the state-of-the-art knowledge on naturally occurring organohalogens, of which more than 3700 are documented. The chapters cover all aspects of this field, including the structural diversity and sources of organohalogens, the mechanisms for their formation and biodegradation, the clinical use of dichloroacetate, and the synthesis of the powerful anticancer chlorine-containing cryptophycin. Both biogenic and abiogenic sources of organohalogens are treated, the latter of which include volcanic emissions and abiogenic formation in soil. Halogenation in humans, fungi, and in the ocean are covered in separate chapters. Sources and biosynthesis of the relatively rare natural organofluorines are also discussed in this volume. By better understanding of the role nature plays in the area of organohalogens, we can more intelligently regulate the production, use, and disposal of man-made organohalogen compounds.
Download or read book Naturally Occurring Organohalogen Compounds A Comprehensive Update written by Gordon W. Gribble and published by Springer Science & Business Media. This book was released on 2009-12-02 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the long association of organohalogen compounds with human activities, nature is the producer of nearly 5,000 halogen-containing chemicals. Once dismissed as accidents of nature or isolation artifacts, organohalogen compounds represent an important and ever growing class of natural products, in many cases exhibiting exceptional biological activity. Since the last comprehensive review in 1996 (Vol. 68, this series), there have been discovered an additional 2,500 organochlorine, organobromine, and other organohalogen compounds. These natural organohalogens are biosynthesized by bacteria, fungi, lichen, plants, marine organisms of all types, insects, and higher animals including humans. These compounds are also formed abiogenically, as in volcanoes, forest fires, and other geothermal events.In some instances, natural organohalogens are precisely the same chemicals that man synthesizes for industrial use, and some of the quantities of these natural chemicals far exceed the quantities emitted by man.
Download or read book Naturally Occurring Organohalogen Compounds written by A. Douglas Kinghorn and published by Springer Nature. This book was released on 2023-07-24 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume is the third in a trilogy that documents naturally occurring organohalogen compounds, bringing the total number — from fewer than 25 in 1968 — to approximately 8,000 compounds to date. Nearly all of these natural products contain chlorine or bromine, with a few containing iodine and, fewer still, fluorine. Produced by ubiquitous marine (algae, sponges, corals, bryozoa, nudibranchs, fungi, bacteria) and terrestrial organisms (plants, fungi, bacteria, insects, higher animals) and universal abiotic processes (volcanos, forest fires, geothermal events), organohalogens pervade the global ecosystem. Newly identified extraterrestrial sources are also documented. In addition to chemical structures, biological activity, biohalogenation, biodegradation, natural function, and future outlook are presented.
Download or read book Natural Production of Organohalogen Compounds written by Gordon W. Gribble and published by Springer Science & Business Media. This book was released on 2003-04-30 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the state-of-the-art knowledge on naturally occurring organohalogens, of which more than 3700 are documented. The chapters cover all aspects of this field, including the structural diversity and sources of organohalogens, the mechanisms for their formation and biodegradation, the clinical use of dichloroacetate, and the synthesis of the powerful anticancer chlorine-containing cryptophycin. Both biogenic and abiogenic sources of organohalogens are treated, the latter of which include volcanic emissions and abiogenic formation in soil. Halogenation in humans, fungi, and in the ocean are covered in separate chapters. Sources and biosynthesis of the relatively rare natural organofluorines are also discussed in this volume. By better understanding of the role nature plays in the area of organohalogens, we can more intelligently regulate the production, use, and disposal of man-made organohalogen compounds.
Download or read book Naturally Produced Organohalogens written by Anders Grimvall and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Should the production and use of chlorine and all chlorinated organic compounds be halted, in view of their adverse effects on the environment and human health? Those in favour argue that certain chlorinated compounds (PCBs, DDT, CFCs, etc.) have large negative environmental effects. The use of chlorine in disinfectants leads to the production of chloroform, while bulk products (PVC) contribute to the production of chlorinated dibenzo-p-dioxins and dibenzofurans when they are burned. Those against argue that chlorine and many chlorinated compounds are essential in the control of human health (the prevention of disease transmitted through drinking water that has not been disinfected), and that chlorinated compounds are indispensable intermediates in many production processes, representing a vast economic value. But such discussions often ignore the fact that Nature contributes significantly to the production of chlorinated organic compounds. More than 1000 such compounds are known, and their contribution to the biogeochemical cycling of chlorine is underestimated. Chlorine is organically bound in large quantities to humic materials, and natural production mechanisms are known for low molecular weight compounds (methyl chloride, chloroform, chlorinated dibenzo-p-dioxins and dibenzofurans). The role of these compounds in the environment is largely unknown. Naturally-Produced Organohalogens gives a complete overview of the present state of knowledge on the subject, giving a much needed balance to the argument sketched out above.
Download or read book New Types of Persistent Halogenated Compounds written by Jaakko Paasivirta and published by Springer Science & Business Media. This book was released on 1999-11-12 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Chemistry is a relatively young science. Interest in this subject, however, is growing very rapidly and, although no agreement has been reached as yet about the exact content and limits of this interdisciplinary discipline, there appears to be increasing interest in seeing environmental topics which are based on chemistry embodied in this subject. One of the first objectives of Environ mental Chemistry must be the study of the environment and of natural chemical processes which occur in the environment. A major purpose of this series on Environmental Chemistry, therefore, is to present a reasonably uniform view of various aspects of the chemistry of the environment and chemical reactions occurring in the environment. The industrial activities of man have given a new dimension to Environ mental Chemistry. We have now synthesized and described over five million chemical compounds and chemical industry produces about hundred and fifty million tons of synthetic chemicals annually. We ship billions of tons of oil per year and through mining operations and other geophysical modifications, large quantities of inorganic and organic materials are released from their natural deposits. Cities and metropolitan areas of up to 15 million inhabitants produce large quantities of waste in relatively small and confined areas. Much of the chemical products and waste products of modern society are released into the environment either during production, storage, transport, use or ultimate disposal. These released materials participate in natural cycles and reactions and frequently lead to interference and disturbance of natural systems.
Download or read book Concentrations of Organohalogen Compounds in the West Nordic Compared to the Baltic Region written by and published by Nordic Council of Ministers. This book was released on 2008 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Organohalogen Compounds written by and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Analytical Chemistry of Organic Halogen Compounds written by L. Mázor and published by Elsevier. This book was released on 2013-09-03 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analytical Chemistry of Organic Halogen Compounds presents the procedures applied in the analysis of organic halogen compounds. This book is composed of eight chapters that discuss the methods involved in the production and application of organic halogen compounds and in overcoming contamination problems caused by these compounds. After briefly dealing with the preparation, characteristics, and reactions of organic halogen compounds, this book goes on discussing the fundamental concepts of methods for the detection of halogens in organic compounds, namely, chlorine, bromine, iodine, and fluorine. The following chapter describes the characteristic features, advantages, and disadvantages of ultramicro and submicro chemical methods. A chapter also examines the qualitative and quantitative studies of organic halogen compounds based on the thermal and chemical stability of these compounds. The concluding chapters discuss the interference or interfering effects of halogens and their elimination in the determination of other elements. A list of physical constants of organic halogen compounds of general pharmaceutical and industrial significance is provided. This book is an ideal source for analytical chemists and other workers who are interested in the theoretical bases of the methods.
Download or read book Organohalogen Compounds in the Marine Environment written by United Nations Environment Programme. Mediterranean Action Plan and published by . This book was released on 1992 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Organohalogen Compounds written by Michael S. Denison and published by . This book was released on 2000-08-01 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Reactive Halogen Compounds in the Atmosphere written by Peter Fabian and published by Springer Science & Business Media. This book was released on 1999-04-09 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Download or read book Biochemistry of Halogenated Organic Compounds written by Kenneth L. Kirk and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry of Halogenated Organic Compounds has been written as a general reference source for researchers in several related areas, including organic chemists, medicinal chemists, pharmacologists, toxicologists, and medical researchers. The development of halogenated compounds as medicinal agents and pharmacological tools and the fascinating biochemi cal processes that have been discovered and studied using these analogues have generated extremely active areas of research and an enormous volume of literature. Thus, halogenated organic compounds pervade every aspect of biochemistry, a fact made apparent by the numerous reviews and monographs available on individual topics-halogenated nucleosides, halogenated carbohydrates, and so forth. Given the quantity of material already written on these topics, some of which material is quite current, it might be asked whether a one-volume review of these subjects is useful, or possible. Having now completed this work, I feel the answer to both questions is an emphatic yes. There are fascinating stories to be related in each area, and, where appropriate, I have attempted to develop these topics . from a historical perspective. For example, the discovery of the anticancer activity of fluorouracil, the unraveling of the several mechanisms of its action, and the development of a host of later generations of anticancer and antiviral agents based on the parent fluoro-, iodo-, bromo-, and trifluoromethylpyrimidines were, and are, contributions of major magnitude to medical science.
Download or read book Naturally Occurring Organohalogen Compounds written by Gordon W. Gribble and published by . This book was released on 1992 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolism Summaries of Selected Halogenated Organic Compounds in Human and Environmental Media written by and published by . This book was released on 1979 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Anthropogenic Compounds written by and published by . This book was released on 2003 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neurotoxicity of Halogenated Organic Compounds written by and published by Elsevier. This book was released on 2023-10-26 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurotoxicity of Halogenated Organic Compounds, Volume 10 covers three groups of Halogenated Organic Compounds (Chlorinated, Brominated, and Fluorinated Compounds) that are legacy and emerging contaminants, providing background information, characteristics, physicochemical properties, environmental contamination, and human exposure. Specific chapters covered in this release include Perspective on Halogenated Organic Compounds, The Neurotoxicity of Polychlorinated Biphenyls (PCBs), Neuroendocrine Effects of Polychlorinated Biphenyls (PCBs), Mechanisms of PCB Neurotoxicity: AHR and THR Dogma meet RYR reality, Microbiome and the Neurotoxicity of Brominated Flame Retardants (BFRs), and much more. Other chapters cover Neuroendocrine Effects of Brominated Flame Retardants (BFRs), Focused on Polybrominated Diphenyl Ethers (PBDEs), Neurochemical Effects of Halogenated Organic Compounds: Possible Mode(s) of action and Structure-Activity Relationships, The Neurotoxic Effects of Perfluoroalkyl Substances (PFAS) in Animal Models and Human Cohorts, Neurochemical Mechanisms of Perfluoroalkyl Substances (PFAS) Neurotoxic Action, and Future Directions and Regulatory aspects of Halogenated Organic Compounds. - Presents the latest on the Neurotoxicity of Halogenated Organic Compounds: Epidemiological, Behavioral and other effects - Covers Neurochemical and Neuroendocrine effects of Halogenated Organic Compounds - Provides Regulatory aspects of Halogenated Organic Compounds
