Download or read book Ordinary Genomes written by Karen-Sue Taussig and published by Duke University Press. This book was released on 2009-09-23 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ordinary Genomes is an ethnography of genomics, a global scientific enterprise, as it is understood and practiced in the Netherlands. Karen-Sue Taussig’s analysis of the Dutch case illustrates how scientific knowledge and culture are entwined: Genetics may transform society, but society also transforms genetics. Taussig traces the experiences of Dutch people as they encounter genetics in research labs, clinics, the media, and everyday life. Through vivid descriptions of specific diagnostic processes, she illuminates the open and evolving nature of genetic categories, the ways that abnormal genetic diagnoses are normalized, and the ways that race, ethnicity, gender, and religion inform diagnoses. Taussig contends that in the Netherlands ideas about genetics are shaped by the desire for ordinariness and the commitment to tolerance, two highly-valued yet sometimes contradictory Dutch social ideals, as well as by Dutch history and concerns about immigration and European unification. She argues that the Dutch enable a social ideal of tolerance by demarcating and containing difference so as to minimize its social threat. It is within this particular construction of tolerance that the Dutch manage the meaning of genetic difference.
Download or read book Comparative Genomics written by Joao Meidanis and published by Springer. This book was released on 2017-09-20 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the 15th International Workshop Comparative Genomics, RECOMB-CG 2017, held in Barcelona, Spain, in October 2017. The 16 full papers presented were carefully reviewed and selected from 32 submissions. The papers report original research in all areas of Comparative Genomics.
Download or read book Ancestors in Our Genome written by Eugene E. Harris (Professor) and published by Oxford University Press, USA. This book was released on 2015 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Geneticist Eugene Harris presents us with the complete and up-to-date account of the evolution of the human genome.
Download or read book Algorithms for Computational Biology written by Ian Holmes and published by Springer. This book was released on 2019-05-21 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the 6th InternationalConference on Algorithms for Computational Biology, AlCoB 2019, held in Berkeley, CA, USA, in May 2019. The 15 full papers presented together with 1 invited paper were carefully reviewed and selected from 30 submissions. They are organized in the following topical sections: Biological networks and graph algorithms; genome rearrangement, assembly and classification; sequence analysis, phylogenetics and other biological processes.
Download or read book Plant Genomes written by Jean-Nicolas Volff and published by Karger Medical and Scientific Publishers. This book was released on 2008-01-01 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent major advances in the field of comparative genomics and cytogenomics of plants, particularly associated with the completion of ambitious genome projects, have uncovered astonishing facets of the architecture and evolutionary history of plant genomes. The aim of this book was to review these recent developments as well as their implications in our understanding of the mechanisms which drive plant diversity. New insights into the evolution of gene functions, gene families and genome size are presented, with particular emphasis on the evolutionary impact of polyploidization and transposable elements. Knowledge on the structure and evolution of plant sex chromosomes, centromeres and microRNAs is reviewed and updated. Taken together, the contributions by internationally recognized experts present a panoramic overview of the structural features and evolutionary dynamics of plant genomes.This volume of Genome Dynamics will provide researchers, teachers and students in the fields of biology and agronomy with a valuable source of current knowledge on plant genomes.
Download or read book Algorithms in Bioinformatics written by Steven L. Salzberg and published by Springer. This book was released on 2009-09-19 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: These proceedings contain papers from the 2009 Workshop on Algorithms in Bioinformatics (WABI), held at the University of Pennsylvania in Philadelphia, Pennsylvania during September 12–13, 2009. WABI 2009 was the ninth annual conference in this series, which focuses on novel algorithms that address imp- tantproblemsingenomics,molecularbiology,andevolution.Theconference- phasizes research that describes computationally e?cient algorithms and data structures that have been implemented and tested in simulations and on real data. WABI is sponsored by the European Association for Theoretical C- puter Science (EATCS) and the International Society for Computational Bi- ogy (ISCB). WABI 2009 was supported by the Penn Genome Frontiers Institute and the Penn Center for Bioinformatics at the University of Pennsylvania. For the 2009 conference, 90 full papers were submitted for review by the Program Committee, and from this strong ?eld of submissions, 34 papers were chosen for presentation at the conference and publication in the proceedings. The ?nal programcovered a wide range of topics including gene interaction n- works, molecular phylogeny, RNA and protein structure, and genome evolution.
Download or read book Bioinformatics and Phylogenetics written by Tandy Warnow and published by Springer. This book was released on 2019-04-08 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a compelling collection of state-of-the-art work in algorithmic computational biology, honoring the legacy of Professor Bernard M.E. Moret in this field. Reflecting the wide-ranging influences of Prof. Moret’s research, the coverage encompasses such areas as phylogenetic tree and network estimation, genome rearrangements, cancer phylogeny, species trees, divide-and-conquer strategies, and integer linear programming. Each self-contained chapter provides an introduction to a cutting-edge problem of particular computational and mathematical interest. Topics and features: addresses the challenges in developing accurate and efficient software for the NP-hard maximum likelihood phylogeny estimation problem; describes the inference of species trees, covering strategies to scale phylogeny estimation methods to large datasets, and the construction of taxonomic supertrees; discusses the inference of ultrametric distances from additive distance matrices, and the inference of ancestral genomes under genome rearrangement events; reviews different techniques for inferring evolutionary histories in cancer, from the use of chromosomal rearrangements to tumor phylogenetics approaches; examines problems in phylogenetic networks, including questions relating to discrete mathematics, and issues of statistical estimation; highlights how evolution can provide a framework within which to understand comparative and functional genomics; provides an introduction to Integer Linear Programming and its use in computational biology, including its use for solving the Traveling Salesman Problem. Offering an invaluable source of insights for computer scientists, applied mathematicians, and statisticians, this illuminating volume will also prove useful for graduate courses on computational biology and bioinformatics.
Download or read book Combinatorics of Genome Rearrangements written by Guillaume Fertin and published by MIT Press. This book was released on 2009 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of a rapidly expanding field of combinatorial optimization, mathematically oriented but offering biological explanations when required. From one cell to another, from one individual to another, and from one species to another, the content of DNA molecules is often similar. The organization of these molecules, however, differs dramatically, and the mutations that affect this organization are known as genome rearrangements. Combinatorial methods are used to reconstruct putative rearrangement scenarios in order to explain the evolutionary history of a set of species, often formalizing the evolutionary events that can explain the multiple combinations of observed genomes as combinatorial optimization problems. This book offers the first comprehensive survey of this rapidly expanding application of combinatorial optimization. It can be used as a reference for experienced researchers or as an introductory text for a broader audience. Genome rearrangement problems have proved so interesting from a combinatorial point of view that the field now belongs as much to mathematics as to biology. This book takes a mathematically oriented approach, but provides biological background when necessary. It presents a series of models, beginning with the simplest (which is progressively extended by dropping restrictions), each constructing a genome rearrangement problem. The book also discusses an important generalization of the basic problem known as the median problem, surveys attempts to reconstruct the relationships between genomes with phylogenetic trees, and offers a collection of summaries and appendixes with useful additional information.
Download or read book From Biotechnology to Genomes written by Ph Goujon and published by World Scientific. This book was released on 2001 with total page 807 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at scientists and non-specialised readers alike, this book retraces the source of national and international biotechnology programmes by examining the origins of biotechnology and its political and economic interpretation by large nations. With a foreword by Andr Goffeau, who initiated the European Yeast Genome Project, the book describes the achievements of the first genetic and physical maps, as well as the political and scientific genesis of the American Human Genome Project. Following these advances, the author discusses the European biotechnology strategy, the birth and implementation of European biotechnology programmes and the yeast genome project. After a detailed description of scientific policy and administrative, technical and scientific achievements, the principal stages of the yeast project and its major benefits are discussed. This enables the reader to obtain a panoramic view of this developing discipline at the dawn of the twenty-first century, as well as a better knowledge of the means deployed at international level. The conclusion gives a very detailed account of the genesis and early stages of this new scientific and technological field called genomics which appears to be a key component of modern industry. By using an epistemological analysis, the conclusion poses the problem of a new representation of life and critically appraises the limitations and deficiencies.
Download or read book Bio Inspired Models of Network Information and Computing Systems written by Gianni A. Di Caro and published by Springer. This book was released on 2014-07-08 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly refereed post-conference proceedings of the 7th International Conference on Bio-Inspired Models of Network, Information and Computing Systems (Bionetics 2012), held in Lugano, Switzerland, in December 2012. The 23 revised full papers presented were carefully reviewed and selected from 40 submissions. They cover topics such as networking, robotics and neural networks, molecular scale and bioinformatics, optimization and bio-inspired modeling in various fields.
Download or read book Advances in New Technology for Targeted Modification of Plant Genomes written by Feng Zhang and published by Springer. This book was released on 2015-04-21 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 50 years, biotechnology has been the major driving force for increasing crop productivity. Particularly, advances in plant genetic engineering technologies have opened up vast new opportunities for plant researchers and breeders to create new crop varieties with desirable traits. Recent development of precise genome modification methods, such as targeted gene knock-out/knock-in and precise gene replacement, moves genetic engineering to another level and offers even more potentials for improving crop production. The work provides an overview of the latest advances on precise genomic engineering technologies in plants. Topics include recombinase and engineered nucleases-mediated targeted modification, negative/positive selection-based homologous recombination and oligo nucleotide-mediated recombination. Finally, challenges and impacts of the new technologies on present regulations for genetic modification organisms (GMOs) will be discussed.
Download or read book Genomes and What to Make of Them written by Barry Barnes and published by University of Chicago Press. This book was released on 2009-05-15 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The announcement in 2003 that the Human Genome Project had completed its map of the entire human genome was heralded as a stunning scientific breakthrough: our first full picture of the basic building blocks of human life. Since then, boasts about the benefits—and warnings of the dangers—of genomics have remained front-page news, with everyone agreeing that genomics has the potential to radically alter life as we know it. For the nonscientist, the claims and counterclaims are dizzying—what does it really mean to understand the genome? Barry Barnes and John Dupré offer an answer to that question and much more in Genomes and What to Make of Them, a clear and lively account of the genomic revolution and its promise. The book opens with a brief history of the science of genetics and genomics, from Mendel to Watson and Crick and all the way up to Craig Venter; from there the authors delve into the use of genomics in determining evolutionary paths—and what it can tell us, for example, about how far we really have come from our ape ancestors. Barnes and Dupré then consider both the power and risks of genetics, from the economic potential of plant genomes to overblown claims that certain human genes can be directly tied to such traits as intelligence or homosexuality. Ultimately, the authors argue, we are now living with a new knowledge as powerful in its way as nuclear physics, and the stark choices that face us—between biological warfare and gene therapy, a new eugenics or a new agricultural revolution—will demand the full engagement of both scientists and citizens. Written in straightforward language but without denying the complexity of the issues, Genomes and What to Make of Them is both an up-to-date primer and a blueprint for the future.
Download or read book Routledge Handbook of Genomics Health and Society written by Sahra Gibbon and published by Routledge. This book was released on 2018-04-17 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook provides an essential resource at the interface of Genomics, Health and Society, and forms a crucial research tool for both new students and established scholars across biomedicine and social sciences. Building from and extending the first Routledge Handbook of Genetics and Society, the book offers a comprehensive introduction to pivotal themes within the field, an overview of the current state of the art knowledge on genomics, science and society, and an outline of emerging areas of research. Key themes addressed include the way genomic based DNA technologies have become incorporated into diverse arenas of clinical practice and research whilst also extending beyond the clinic; the role of genomics in contemporary ‘bioeconomies’; how challenges in the governance of medical genomics can both reconfigure and stabilise regulatory processes and jurisdictional boundaries; how questions of diversity and justice are situated across different national and transnational terrains of genomic research; and how genomics informs – and is shaped by – developments in fields such as epigenetics, synthetic biology, stem cell, microbial and animal model research. Presenting cutting edge research from leading social science scholars, the Handbook provides a unique and important contribution to the field. It brings a rich and varied cross disciplinary social science perspective that engages with both the history and contemporary context of genomics and ‘post-genomics’, and considers the now global and transnational terrain in which these developments are unfolding.
Download or read book Genetic Entropy the Mystery of the Genome written by John C. Sanford and published by Ivan Press. This book was released on 2005 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. John Sanford, a retired Cornell Professor, shows in Genetic Entropy and the Mystery of the Genome that the Primary Axiom is false. The Primary Axiom is the foundational evolutionary premise - that life is merely the result of mutations and natural selection. In addition to showing compelling theoretical evidence that whole genomes can not evolve upward, Dr. Sanford presents strong evidence that higher genomes must in fact degenerate over time. This book strongly refutes the Darwinian concept that man is just the result of a random and pointless natural process.
Download or read book Mestizo Genomics written by Peter Wade and published by Duke University Press. This book was released on 2014-04-04 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: In genetics laboratories in Latin America, scientists have been mapping the genomes of local populations, seeking to locate the genetic basis of complex diseases and to trace population histories. As part of their work, geneticists often calculate the European, African, and Amerindian genetic ancestry of populations. Some researchers explicitly connect their findings to questions of national identity and racial and ethnic difference, bringing their research to bear on issues of politics and identity. Drawing on ethnographic research in Brazil, Colombia, and Mexico, the contributors to Mestizo Genomics explore how the concepts of race, ethnicity, nation, and gender enter into and are affected by genomic research. In Latin America, national identities are often based on ideas about mestizaje (race mixture), rather than racial division. Since mestizaje is said to involve relations between European men and indigenous or African women, gender is a key factor in Latin American genomics and in the analyses in this book. Also important are links between contemporary genomics and recent moves toward official multiculturalism in Brazil, Colombia, and Mexico. One of the first studies of its kind, Mestizo Genomics sheds new light on the interrelations between "race," identity, and genomics in Latin America. Contributors. Adriana Díaz del Castillo H., Roosbelinda Cárdenas, Vivette García Deister, Verlan Valle Gaspar Neto, Michael Kent, Carlos López Beltrán, María Fernanda Olarte Sierra, Eduardo Restrepo, Mariana Rios Sandoval, Ernesto Schwartz-Marín, Ricardo Ventura Santos, Peter Wade
Download or read book Ordinary Geniuses written by Gino Segre and published by Penguin. This book was released on 2013-11-26 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fascinating tribute to the forefathers of two of today’s most exciting scientific fields Thanks to Max Delbruck and George Gamow, today we have mapped the human genome and understand the ramifications of the Big Bang. In his characteristically inviting and elegant style, Gino Segre brings to life the story of these two great scientists and their long friendship and offers an accessible inside look the people behind the scenes of science—the collaboration and competition, the quirks and failures, the role of intuition and luck, and the sense of wonder and curiosity that keeps these extraordinary minds going.
Download or read book Encyclopedia of Microbiology written by and published by Academic Press. This book was released on 2009-01-14 with total page 4358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Available as an exclusive product with a limited print run, Encyclopedia of Microbiology, 3e, is a comprehensive survey of microbiology, edited by world-class researchers. Each article is written by an expert in that specific domain and includes a glossary, list of abbreviations, defining statement, introduction, further reading and cross-references to other related encyclopedia articles. Written at a level suitable for university undergraduates, the breadth and depth of coverage will appeal beyond undergraduates to professionals and academics in related fields. 16 separate areas of microbiology covered for breadth and depth of content Extensive use of figures, tables, and color illustrations and photographs Language is accessible for undergraduates, depth appropriate for scientists Links to original journal articles via Crossref 30% NEW articles and 4-color throughout – NEW!
