Download or read book High Resolution Imaging in Microscopy and Ophthalmology written by Josef F. Bille and published by Springer. This book was released on 2019-08-13 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.

Download or read book Handbook of Pediatric Retinal OCT and the Eye Brain Connection E Book written by Cynthia A. Toth and published by Elsevier Health Sciences. This book was released on 2019-05-04 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical Coherence Tomography (OCT) plays a vital role in pediatric retina diagnosis, often revealing unrecognized retinal disorders and connections to brain injury, disease, and delayed neurodevelopment. Handbook of Pediatric Retinal OCT and the Eye-Brain Connection provides authoritative, up-to-date guidance in this promising area, showing how to optimize imaging in young children and infants, how to accurately interpret these images, and how to identify links between these images and brain and developmental disorders. - Illustrates optimal methods of OCT imaging of children and infants, how to avoid pitfalls, and how to recognize and avoid artifacts - Explains how the OCT image may relate to brain disease and delayed neurodevelopment - Features more than 200 high-quality images and scans that depict the full range of disease in infants and young children - Provides guidance in identifying retinal layers and important abnormalities. - Covers the structural features of the retina and optic nerve head in developmental, acquired, or inherited conditions that affect the eye and visual pathways - Offers practical ways to set up imaging programs in the clinic, operating room, or neonatal nursery

Download or read book Neurovascular Imaging written by Anna Devor and published by Frontiers E-books. This book was released on 2012-02-01 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent technological advances are significantly enhancing ones ability to image the interplay of neuronal activity, metabolism, and the associated vascular response with high spatial and temporal resolution. This Research Topic will cover these recent technological advances as well as the impact they have had on understanding the coupling of neuronal, metabolic, and vascular responses. We invite contributions to highlight new original research and to provide a forum for discussion of hot neurovascular topics. Potential contributions include, but are not limited by the following examples: - Development and application of novel optical technologies for imaging of neuronal, metabolic and vascular activity. Examples include 2-Photon Microscopy, Optical Coherence Tomography, and Second Harmonic Microscopy. - Intravital imaging of metabolites such as NADH and flavoproteins - Application of optical methods for manipulation of neuroglial circuits and vascular architectonics - Development of novel Magnetic Resonance contrasts for noninvasive imaging of blood flow, volume, and oxygen consumption. - Application of imaging tools for studying of neurovascular dysfunctions such as stroke, vascular dementia and Alzheimer’s Disease - Hypotheses, Perspectives, Commentaries and Opinions with regards to the body of recent publications that utilize imaging tools for investigation of neurogliovascular communication and the regulation of cerebral blood flow

Download or read book Optical Coherence Tomography written by Wolfgang Drexler and published by Springer Science & Business Media. This book was released on 2008-12-10 with total page 1346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical coherence tomography (OCT) is the optical analog of ultrasound imaging and is emerging as a powerful imaging technique that enables non-invasive, in vivo, high resolution, cross-sectional imaging in biological tissue. This book introduces OCT technology and applications not only from an optical and technological viewpoint, but also from biomedical and clinical perspectives. The chapters are written by leading research groups, in a style comprehensible to a broad audience.

Download or read book Optical Coherence Tomography in Multiple Sclerosis written by Axel Petzold and published by Springer. This book was released on 2018-02-21 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a clinical context to optical coherence tomography (OCT) findings, while considering the differential diagnosis and providing patient management guidance. Relevant anatomical and technical aspects are discussed, followed by a pragmatic illustration of the use of OCT for the clinical spectrum of multiple sclerosis and optic neuritis, and finishing with information on monitoring ocular side effects of recently approved disease-modifying treatments in multiple sclerosis. Optical Coherence Tomography in Multiple Sclerosis: Clinical Applications is aimed at clinical neurologists working with patients suffering from MS and general neurologists who see patients with visual symptoms in their daily practice. Ophthalmologists sharing clinical responsibilities with neurologists for patients under disease-modifying treatments will also find the book of interest.

Download or read book Optical Coherence Tomography in Neurologic Diseases written by Peter A. Calabresi and published by Cambridge University Press. This book was released on 2015-05-14 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive review of the use of optical coherence tomography in neurological diseases for neurologists, neuro-ophthalmologists, and neuroradiologists.

Download or read book OCT Atlas written by Nagahisa Yoshimura and published by Springer. This book was released on 2014-06-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: OCT provided a great advantage over other diagnostic modalities, as it could noninvasively provide tomographic images of the retina of a living eye. As a result, a number of new findings in retinal diseases were made using the time-domain OCT. OCT has now become an essential medical equipment OCT has now become an essential medical equipment in ophthalmic care and quality textbooks describing the functionality of OCT are very important in the education of young ophthalmologists and eye care personnel. In this book are chosen high quality OCT images of rather common diseases as well as images of several rare diseases.

Download or read book Coherent Light Microscopy written by Pietro Ferraro and published by Springer Science & Business Media. This book was released on 2011-02-09 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the latest achievements in the field of optical coherent microscopy. While many other books exist on microscopy and imaging, this book provides a unique resource dedicated solely to this subject. Similarly, many books describe applications of holography, interferometry and speckle to metrology but do not focus on their use for microscopy. The coherent light microscopy reference provided here does not focus on the experimental mechanics of such techniques but instead is meant to provide a users manual to illustrate the strengths and capabilities of developing techniques. The areas of application of this technique are in biomedicine, medicine, life sciences, nanotechnology and materials sciences.

Download or read book The Development and Clinical Application of Innovative Optical Ophthalmic Imaging Techniques written by Peng Xiao and published by Frontiers Media SA. This book was released on 2022-12-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Optics Letters written by and published by . This book was released on 2008 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book In Vivo Optical Imaging of Brain Function Second Edition written by Ron D. Frostig and published by CRC Press. This book was released on 2009-05-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques and their applications for the growing field of functional imaging in the live brain using optical imaging techniques. New in the Second Edition: Voltage-sensitive dyes imaging in awake behaving animals Imaging based on genetically encoded probes Imaging of mitochondrial auto-fluorescence as a tool for cortical mapping Using pH-sensitive dyes for functional mapping Modulated imaging Calcium imaging of neuronal activity using 2-photon microscopy Fourier approach to optical imaging Fully updated chapters from the first edition Leading Authorities Explore the Latest Techniques Updated to reflect continuous development in this emerging research area, this new edition, as with the original, reaches across disciplines to review a variety of non-invasive optical techniques used to study activity in the living brain. Leading authorities from such diverse areas as biophysics, neuroscience, and cognitive science present a host of perspectives that range from a single neuron to large assemblies of millions of neurons, captured at various temporal and spatial resolutions. Introducing techniques that were not available just a few years ago, the authors describe the theory, setup, analytical methods, and examples that highlight the advantages of each particular method.

Download or read book Video Bioinformatics written by Bir Bhanu and published by Springer. This book was released on 2015-12-16 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advances of live cell video imaging and high-throughput technologies for functional and chemical genomics provide unprecedented opportunities to understand how biological processes work in subcellularand multicellular systems. The interdisciplinary research field of Video Bioinformatics is defined by BirBhanu as the automated processing, analysis, understanding, data mining, visualization, query-basedretrieval/storage of biological spatiotemporal events/data and knowledge extracted from dynamic imagesand microscopic videos. Video bioinformatics attempts to provide a deeper understanding of continuousand dynamic life processes.Genome sequences alone lack spatial and temporal information, and video imaging of specific moleculesand their spatiotemporal interactions, using a range of imaging methods, are essential to understandhow genomes create cells, how cells constitute organisms, and how errant cells cause disease. The bookexamines interdisciplinary research issues and challenges with examples that deal with organismal dynamics,intercellular and tissue dynamics, intracellular dynamics, protein movement, cell signaling and softwareand databases for video bioinformatics.Topics and Features• Covers a set of biological problems, their significance, live-imaging experiments, theory andcomputational methods, quantifiable experimental results and discussion of results.• Provides automated methods for analyzing mild traumatic brain injury over time, identifying injurydynamics after neonatal hypoxia-ischemia and visualizing cortical tissue changes during seizureactivity as examples of organismal dynamics• Describes techniques for quantifying the dynamics of human embryonic stem cells with examplesof cell detection/segmentation, spreading and other dynamic behaviors which are important forcharacterizing stem cell health• Examines and quantifies dynamic processes in plant and fungal systems such as cell trafficking,growth of pollen tubes in model systems such as Neurospora Crassa and Arabidopsis• Discusses the dynamics of intracellular molecules for DNA repair and the regulation of cofilintransport using video analysis• Discusses software, system and database aspects of video bioinformatics by providing examples of5D cell tracking by FARSIGHT open source toolkit, a survey on available databases and software,biological processes for non-verbal communications and identification and retrieval of moth imagesThis unique text will be of great interest to researchers and graduate students of Electrical Engineering,Computer Science, Bioengineering, Cell Biology, Toxicology, Genetics, Genomics, Bioinformatics, ComputerVision and Pattern Recognition, Medical Image Analysis, and Cell Molecular and Developmental Biology.The large number of example applications will also appeal to application scientists and engineers.Dr. Bir Bhanu is Distinguished Professor of Electrical & C omputer Engineering, Interim Chair of theDepartment of Bioengineering, Cooperative Professor of Computer Science & Engineering, and MechanicalEngineering and the Director of the Center for Research in Intelligent Systems, at the University of California,Riverside, California, USA.Dr. Prue Talbot is Professor of Cell Biology & Neuroscience and Director of the Stem Cell Center and Core atthe University of California Riverside, California, USA.

Download or read book Advances in Ocular Imaging and Biometry written by Zhenzhen Liu and published by Frontiers Media SA. This book was released on 2022-11-09 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Neural Metabolism In Vivo written by In-Young Choi and published by Springer Science & Business Media. This book was released on 2012-03-14 with total page 1168 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the preface: “Neural Metabolism In Vivo aims to provide a comprehensive overview of neurobiology by presenting the basic principles of up-to-date and cutting-edge technology, as well as their application in assessing the functional, morphological and metabolic aspects of the brain. Investigation of neural activity of the living brain via neurovascular coupling using multimodal imaging techniques extended our understanding of fundamental neurophysiological mechanisms, regulation of cerebral blood flow in connection to neural activity and the interplay between neurons, astrocytes and blood vessels. Constant delivery of glucose and oxygen for energy metabolism is vital for brain function, and the physiological basis of neural activity can be assessed through measurements of cerebral blood flow and consumption of glucose and oxygen.... This book presents the complex physiological and neurochemical processes of neural metabolism and function in response to various physiological conditions and pharmacological stimulations. Neurochemical detection technologies and quantitative aspects of monitoring cerebral energy substrates and other metabolites in the living brain are described under the “Cerebral metabolism of antioxidants, osmolytes and others in vivo” section. Altogether, the advent of new in vivo tools has transformed neuroscience and neurobiology research, and demands interdisciplinary approaches as each technology could only approximate a very small fraction of the true complexity of the underlying biological processes. However, translational values of the emerging in vivo methods to the application of preclinical to clinical studies cannot be emphasized enough. Thus, it is our hope that advances in our understanding of biochemical, molecular, functional and physiological processes of the brain could eventually help people with neurological problems, which are still dominated by the unknowns.” -- In-Young Choi and Rolf Gruetter

Download or read book Proceedings of Ophthalmic Technologies written by and published by . This book was released on 2006 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biomedical Optical Imaging written by James G. Fujimoto and published by Oxford University Press. This book was released on 2009-04-22 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical optical imaging is a rapidly emerging research area with widespread fundamental research and clinical applications. This book gives an overview of biomedical optical imaging with contributions from leading international research groups who have pioneered many of these techniques and applications. A unique research field spanning the microscopic to the macroscopic, biomedical optical imaging allows both structural and functional imaging. Techniques such as confocal and multiphoton microscopy provide cellular level resolution imaging in biological systems. The integration of this technology with exogenous chromophores can selectively enhance contrast for molecular targets as well as supply functional information on processes such as nerve transduction. Novel techniques integrate microscopy with state-of-the-art optics technology, and these include spectral imaging, two photon fluorescence correlation, nonlinear nanoscopy; optical coherence tomography techniques allow functional, dynamic, nanoscale, and cross-sectional visualization. Moving to the macroscopic scale, spectroscopic assessment and imaging methods such as fluorescence and light scattering can provide diagnostics of tissue pathology including neoplastic changes. Techniques using light diffusion and photon migration are a means to explore processes which occur deep inside biological tissues and organs. The integration of these techniques with exogenous probes enables molecular specific sensitivity.

Download or read book Molecular Imaging Basic Principles And Applications In Biomedical Research 3rd Edition written by Markus Rudin and published by World Scientific. This book was released on 2020-04-04 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied.The third edition has been extended considerably. This holds for the chapter on imaging modalities, which now includes sections on intravital microscopy and mass spectrometric imaging. All chapters have been updated and a new chapter on the challenges of translating molecular imaging solutions for clinical use has been added.