Download or read book Optical Feedback Sensing in Microfluidics written by Yu Zhao and published by . This book was released on 2017 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical feedback interferometry (OFI) is an emerging sensing technique which has been studied in fluidic systems. This sensing scheme is based on the modulation of the laser emission output power and/or the junction voltage induced by the interaction between the back-scattered light from a distant target and the laser inner cavity light. Thanks to the Doppler Effect, OFI can precisely measure the velocity of seeding particles in flowing liquids which is much required in chemical engineering and biomedical fields. In the present thesis, optical feedback interferometry performance for microscale flow sensing is studied theoretically and experimentally. A new numerical modeling approach based on multi-physics numerical simulations for OFI signal simulation in the micro-scale flowmetry configuration is presented that highlight the sensor performances. In this model, many factors are involved such as particle concentration and laser-particle scattering angle distribution and flow velocity distribution. The flow rate measurement shows good agreement with the modeling. The implementation of OFI based sensors in multiple fluidic systems, investigating the impact of the fluidic chip specific configuration on the sensor signal.Finally, a compact OFI flowmetry sensor based on Vertical-Cavity Surface-Emitting Lasers (VCSELs) using micro optical fabrication techniques is demonstrated as well. The simulation method for the design and the microfabrication procedures are detailed. After an evaluation of the experimental results, the capabilities of this new OFI sensor in microfluidic measurements are emphasized, thus demonstrating an open path towards ultra-compact microfluidic systems based on the OFI sensing technique.
Download or read book Implementation of a High Resolution Optical Feedback Interferometer for Microfluidics Applications written by Raul da Costa Moreira and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent progress of interferometric sensors based on the optical feedback in a laser diode have demonstrated possibility for measurement of flow rates and flow-profiles at the micro-scale. That type of compact and embedded sensors is very promising for a research and industrial field -microfluidics - that is a growing domain of activities, at the frontiers of the physics, the chemical science, the biology and the biomedical. However, the acquisition of flow rate or local velocity at high resolution remains a very challenging issue, and the sensors that have been proposed so far did not have been giving sufficient information on the nature of the particles flowing. The present thesis is driven to the implementation, validation and evaluation of the sensing performances of the optical feedback interferometry technology in both chemical and biomedical fields of applications. The elaboration of a new generation of sensors that will provide both a high spatial resolution for 2D Doppler imaging is presented, as well as a methodology that gives further information on the flowing particles concentration and/or dimensions. Then, a new embedded optical feedback interferometry imager for flowmetry has been realized using a 2-axis beamsteering mirror mounted on Micro-Electro-Mechanical Systems (MEMS) thus taking the full advantage of the compactness offered by the optical feedback interferometry sensing scheme. While previous works on optical feedback interferometry flowmetry have been limited to high particle densities fluids in single or multiple scattering regimes, we present also a sensing technique based on the optical feedback interferometry scheme in a laser diode that enables single particle detection at micro and nanoscales through the Doppler-Fizeau effect. Thanks to the proposed signal processing, this sensing technique can detect the presence of single spherical polystyrene micro/nanospheres seeded in watery suspensions, and measure their flow velocity, even when their diameter is below half the laser wavelength. It discriminates particle by their diameter up to a ratio of 5 between large and small ones while most of the technologies for particle characterization is bulk and requires manipulation of the fluid with small volume handling, precise flow and concentration control. Altogether, the results presented in this thesis realize a major improvement for the use of optical feedback interferometry in the chemical engineering or biomedical applications involving micro-scale flows.
Download or read book Timing based Dynamic Control and Optical Sensing based Feedback Control in DEP Microfluidics written by Kai-Liang Wang and published by . This book was released on 2007 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Droplet and Digital Microfluidics written by Sanket Goel and published by Elsevier. This book was released on 2024-03-11 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Droplet and Digital Microfluidics: Ideation to Implementation is a detailed introduction to the dynamics of droplet and digital microfluidics, also featuring coverage of new methods and applications. The explosion of applications of microelectromechanical systems (MEMS) in recent years has driven demand for expertise and innovation in fluid flow in the microchannels they contain. In this book, detailed descriptions of methods for biological and chemical applications of microfluidics are provided, along with supporting foundational knowledge. In addition, the principles of droplet and digital microfluidics are explained, along with their different applications and governing physics. New additions to the technological knowledgebase that enable advances in droplet and digital microfluidics include machine learning and exciting future avenues for research. - Provides step-by-step fabrication, testing, and characterization instructions in each chapter to support implementation - Includes explanations of applications and methods in biological and chemical settings - Describes the path to automation of digital and droplet microfluidic platforms
Download or read book Microfluidic Biosensors written by Wing Cheung Mak and published by Elsevier. This book was released on 2022-11-05 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidic Biosensors provides a comprehensive overview covering the most recent emerging technologies on the design, fabrication, and integration of microfluidics with transducers. These form various integrated microfluidic biosensors with device configurations ranging from 2D to 4D levels. Coverage also includes advanced printed microfluidic biosensors, flexible microfluidics for wearable biosensors, autonomous lab-on-a-chip biosensors, CMOS-base microanalysis systems, and microfluidic devices for mobile phone biosensing. The editors and contributors of this book represent both academia and industry, come from a varied range of backgrounds, and offer a global perspective. This book discusses the design and principle of microfluidic systems and uses them for biosensing applications. The microfluidic fabrication technologies covered in this book provide an up-to-date view, allowing the community to think of new ways to overcome challenges faced in this field. The focus is on existing and emerging technologies not currently being analyzed extensively elsewhere, providing a unique perspective and much-needed content. The editors have crafted this book to be accessible to all levels of academics from graduate students, researchers, and professors working in the fields of biosensors, microfluidics design, material science, analytical chemistry, biomedical devices, and biomedical engineering. It can also be useful for industry professionals working for microfluidic device manufacturers, or in the industry of biosensors and biomedical devices. - Presents an in-depth overview of microfluidic biosensors and associated emerging technologies such as printed microfluidics and novel transducers - Addresses a range of microfluidic biosensors with device configurations ranging from 2D to 4D levels - Includes the commercialization aspects of microfluidic biosensors that provide insights for scientists and engineers in research and development
Download or read book Microfluidics in Detection Science written by Fatima H Labeed and published by Royal Society of Chemistry. This book was released on 2014-10-24 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of a miniaturised laboratory on a disposable chip is now a reality, and in everyday use in industry, medicine and defence. New devices are launched all the time, prompting the need for a straightforward guide to the design and manufacture of lab-on-a-chip (LOC) devices. This book presents a modular approach to the construction and integration of LOC components in detection science. The editors have brought together some of the leading experts from academia and industry to present an accessible guide to the technology available and its potential. Several chapters are devoted to applications, presenting both the sampling regime and detection methods needed. Further chapters describe the integration of LOC devices, not only with each other but also into existing technologies. With insights into LOC applications, from biosensing to molecular and chemical analysis, and presenting scaled-down versions of existing technology alongside unique approaches that exploit the physics of the micro and nano-scale, this book will appeal to newcomers to the field and practitioners requiring a convenient reference.
Download or read book Handbook of Optical Fibers written by Gang-Ding Peng and published by Springer. This book was released on 2019-08-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research- and application-oriented book covers main topical areas of optical fibers. The selection of the chapters is weighted on technological and application-specific topics, very much a reflection of where research is heading to and what researchers are looking for. Chapters are arranged in a user-friendly format essentially self-contained and with extensive cross-references. They are organized in the following sections: - Optical Fiber Communication | Editors: Ming-Jun Li and Chao Lu - Solitons and Nonlinear Waves in Optical Fibers | Editor: Boris A. Malomed - Optical Fiber Fabrication | Editor: Hairul Azhar Bin Abdul Rashid - Active Optical Fibers | Editor: Kyunghwan Oh - Special Optical Fibers | Editors: Perry Shum and Zhilin Xu - Optical Fiber Measurement | Editor: Jianzhong Zhang - Optical Fiber Devices | Editors: John Canning and Tuan Guo - Optical Fiber Device Measurement | Editor: Yanhua Luo - Distributed Optical Fiber Sensing | Editor: Yosuke Mizuno - Optical Fiber Sensors for Industrial Applications | Editor: Tong Sun OBE - Polymer Optical Fiber Sensing | Editor: Ginu Rajan - Photonic Crystal Fiber Sensing | Editor: D. N. Wang - Optical Fiber Microfluidic Sensors | Editor: Yuan Gong
Download or read book Microfluidics written by Yujun Song and published by John Wiley & Sons. This book was released on 2018-01-04 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book offering a global overview of fundamental microfluidics and the wide range of possible applications, for example, in chemistry, biology, and biomedical science. As such, it summarizes recent progress in microfluidics, including its origin and development, the theoretical fundamentals, and fabrication techniques for microfluidic devices. The book also comprehensively covers the fluid mechanics, physics and chemistry as well as applications in such different fields as detection and synthesis of inorganic and organic materials. A useful reference for non-specialists and a basic guideline for research scientists and technicians already active in this field or intending to work in microfluidics.
Download or read book Highly Integrated Microfluidics Design written by Dan E. Angelescu and published by Artech House. This book was released on 2011 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent development of microfluidics has lead to the concept of lab-on-a-chip, where several functional blocks are combined into a single device that can perform complex manipulations and characterizations on the microscopic fluid sample. However, integration of multiple functionalities on a single device can be complicated. This a cutting-edge resource focuses on the crucial aspects of integration in microfluidic systems. It serves as a one-stop guide to designing microfluidic systems that are highly integrated and scalable. This practical book covers a wide range of critical topics, from fabrication techniques and simulation tools, to actuation and sensing functional blocks and their inter-compatibility. This unique reference outlines the benefits and drawbacks of different approaches to microfluidic integration and provides a number of clear examples of highly integrated microfluidic systems.
Download or read book Microfluidics and Nanofluidics Handbook written by Sushanta K. Mitra and published by CRC Press. This book was released on 2016-04-19 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive handbook presents fundamental aspects, fabrication techniques, introductory materials on microbiology and chemistry, measurement techniques, and applications of microfluidics and nanofluidics. The second volume focuses on topics related to experimental and numerical methods. It also covers fabrication and applications in a variety of areas, from aerospace to biological systems. Reflecting the inherent nature of microfluidics and nanofluidics, the book includes as much interdisciplinary knowledge as possible. It provides the fundamental science background for newcomers and advanced techniques and concepts for experienced researchers and professionals.
Download or read book Microfluidics and Nanotechnology written by Eric Lagally and published by CRC Press. This book was released on 2017-12-19 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: An increasing number of technologies are being used to detect minute quantities of biomolecules and cells. However, it can be difficult to determine which technologies show the most promise for high-sensitivity and low-limit detection in different applications. Microfluidics and Nanotechnology: Biosensing to the Single Molecule Limit details proven approaches for the detection of single cells and even single molecules—approaches employed by the world’s foremost microfluidics and nanotechnology laboratories. While similar books concentrate only on microfluidics or nanotechnology, this book focuses on the combination of soft materials (elastomers and other polymers) with hard materials (semiconductors, metals, and glass) to form integrated detection systems for biological and chemical targets. It explores physical and chemical—as well as contact and noncontact—detection methods, using case studies to demonstrate system capabilities. Presenting a snapshot of the current state of the art, the text: Explains the theory behind different detection techniques, from mechanical resonators for detecting cell density to fiber-optic methods for detecting DNA hybridization, and beyond Examines microfluidic advances, including droplet microfluidics, digital microfluidics for manipulating droplets on the microscale, and more Highlights an array of technologies to allow for a comparison of the fundamental advantages and challenges of each, as well as an appreciation of the power of leveraging scalability and integration to achieve sensitivity at low cost Microfluidics and Nanotechnology: Biosensing to the Single Molecule Limit not only serves as a quick reference for the latest achievements in biochemical detection at the single-cell and single-molecule levels, but also provides researchers with inspiration for further innovation and expansion of the field.
Download or read book Issues in Nanotechnology and Micotechnology Materials and Molecular Research 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Nanotechnology and Micotechnology—Materials and Molecular Research: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Nanotechnology. The editors have built Issues in Nanotechnology and Micotechnology—Materials and Molecular Research: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nanotechnology in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Nanotechnology and Micotechnology—Materials and Molecular Research: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Microfluidics Based Microsystems written by S. Kakaç and published by Springer Science & Business Media. This book was released on 2010-09-10 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains an archival record of the NATO Advanced Study Institute on Microfluidics Based Microsystems – Fundamentals and App- cations held in Çe ?me-Izmir, Turkey, August 23–September 4, 2009. ASIs are intended to be high-level teaching activity in scientific and technical areas of current concern. In this volume, the reader may find interesting chapters and various microsystems fundamentals and applications. As the world becomes increasingly concerned with terrorism, early - spot detection of terrorist’s weapons, particularly bio-weapons agents such as bacteria and viruses are extremely important. NATO Public Diplomacy division, Science for Peace and Security section support research, Advanced Study Institutes and workshops related to security. Keeping this policy of NATO in mind, we made such a proposal on Microsystems for security. We are very happy that leading experts agreed to come and lecture in this important NATO ASI. We will see many examples that will show us Microfluidics usefulness for rapid diagnostics following a bioterrorism attack. For the applications in national security and anti-terrorism, microfluidic system technology must meet the challenges. To develop microsystems for security and to provide a comprehensive state-of-the-art assessment of the existing research and applications by treating the subject in considerable depth through lectures from eminent professionals in the field, through discussions and panel sessions are very beneficial for young scientists in the field.
Download or read book Encyclopedia of Microfluidics and Nanofluidics written by Dongqing Li and published by Springer Science & Business Media. This book was released on 2008-08-06 with total page 2242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering all aspects of transport phenomena on the nano- and micro-scale, this encyclopedia features over 750 entries in three alphabetically-arranged volumes including the most up-to-date research, insights, and applied techniques across all areas. Coverage includes electrical double-layers, optofluidics, DNC lab-on-a-chip, nanosensors, and more.
Download or read book Microfluidics and Nanofluidics Handbook 2 Volume Set written by Sushanta K. Mitra and published by CRC Press. This book was released on 2011-09-20 with total page 1767 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, two-volume handbook on Microfluidics and Nanofluidics, this text covers fundamental aspects, fabrication techniques, introductory materials on microbiology and chemistry, measurement techniques, and applications with special emphasis on the energy sector. Each chapter begins with introductory coverage to a subject and then narrows in on advanced techniques and concepts, thus making it valuable to students and practitioners. The author pays special attention to applications of microfluidics in the energy sector and provides insight into the world of opportunities nanotechnology has to offer. Figures, tables, and equations to illustrate concepts.
Download or read book Microfluidics for Biosensing and Diagnostics written by David W. Inglis and published by MDPI. This book was released on 2021-01-05 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Efforts to miniaturize sensing and diagnostic devices and to integrate multiple functions into one device have caused massive growth in the field of microfluidics and this integration is now recognized as an important feature of most new diagnostic approaches. These approaches have and continue to change the field of biosensing and diagnostics. In this Special Issue, we present a small collection of works describing microfluidics with applications in biosensing and diagnostics.
Download or read book Advances in Microfluidics Technology for Diagnostics and Detection written by David Kinahan and published by MDPI. This book was released on 2021-09-06 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics and lab-on-a-chip have, in recent years, come to the forefront in diagnostics and detection. At point-of-care, in the emergency room, and at the hospital bed or GP clinic, lab-on-a-chip offers the potential to rapidly detect time-critical and life-threatening diseases such as sepsis and bacterial meningitis. Furthermore, portable and user-friendly diagnostic platforms can enable disease diagnostics and detection in resource-poor settings where centralised laboratory facilities may not be available. At point-of-use, microfluidics and lab-on-chip can be applied in the field to rapidly identify plant pathogens, thus reducing the need for damaging broad spectrum pesticides while also reducing food losses. Microfluidics can also be applied to the continuous monitoring of water quality and can support policy-makers and protection agencies in protecting the environment. Perhaps most excitingly, microfluidics also offers the potential to enable entirely new diagnostic tests that cannot be implemented using conventional laboratory tools. Examples of microfluidics at the frontier of new medical diagnostic tests include early detection of cancers through circulating tumour cells (CTCs) and highly sensitive genetic tests using droplet-based digital PCR. This Special Issue on “Advances in Microfluidics Technology for Diagnostics and Detection” aims to gather outstanding research and to carry out comprehensive coverage of all aspects related to microfluidics in diagnostics and detection.
