Download or read book Opportunities for Breakthroughs in Large Scale Computational Simulation and Design written by and published by . This book was released on 2002 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: Opportunities for breakthroughs in the large-scale computational simulation and design of aerospace vehicles are presented. Computational fluid dynamics tools to be used within multidisciplinary analysis and design methods are emphasized. The opportunities stem from speedups and robustness improvements in the underlying unit operations associated with simulation (geometry modeling, grid generation, physical modeling, analysis, etc.). Further, an improved programming environment can synergistically integrate these unit operations to leverage the gains. The speedups result from reducing the problem setup time through geometry modeling and grid generation operations, and reducing the solution time through the operation counts associated with solving the discretized equations to a sufficient accuracy. The opportunities are addressed only at a general level here, but an extensive list of references containing further details is included.
Download or read book Opportunities for Breakthroughs in Large Scale Computational Simulation and Design written by National Aeronautics and Space Adm Nasa and published by Independently Published. This book was released on 2018-09-16 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: Opportunities for breakthroughs in the large-scale computational simulation and design of aerospace vehicles are presented. Computational fluid dynamics tools to be used within multidisciplinary analysis and design methods are emphasized. The opportunities stem from speedups and robustness improvements in the underlying unit operations associated with simulation (geometry modeling, grid generation, physical modeling, analysis, etc.). Further, an improved programming environment can synergistically integrate these unit operations to leverage the gains. The speedups result from reducing the problem setup time through geometry modeling and grid generation operations, and reducing the solution time through the operation counts associated with solving the discretized equations to a sufficient accuracy. The opportunities are addressed only at a general level here, but an extensive list of references containing further details is included. The opportunities discussed are being addressed through the Fast Adaptive Aerospace Tools (FAAST) element of the Advanced Systems Concept to Test (ASCoT) and the third Generation Reusable Launch Vehicles (RLV) projects at NASA Langley Research Center. The overall goal is to enable greater inroads into the design process with large-scale simulations.Alexandrov, Natalia and Alter, Stephen J. and Atkins, Harold L. and Bey, Kim S. and Bibb, Karen L. and Biedron, Robert T. and Carpenter, Mark H. and Cheatwood, F. McNeil and Drummond, Philip J. and Gnoffo, Peter A.Langley Research CenterAEROSPACE VEHICLES; COMPUTATIONAL FLUID DYNAMICS; SIMULATION; COMPUTER AIDED DESIGN; GRID GENERATION (MATHEMATICS); PROGRAMMING ENVIRONMENTS; REUSABLE LAUNCH VEHICLES; MULTIDISCIPLINARY DESIGN OPTIMIZATION
Download or read book Computational Approaches for Aerospace Design written by Andy Keane and published by John Wiley & Sons. This book was released on 2005-08-05 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last fifty years, the ability to carry out analysis as a precursor to decision making in engineering design has increased dramatically. In particular, the advent of modern computing systems and the development of advanced numerical methods have made computational modelling a vital tool for producing optimized designs. This text explores how computer-aided analysis has revolutionized aerospace engineering, providing a comprehensive coverage of the latest technologies underpinning advanced computational design. Worked case studies and over 500 references to the primary research literature allow the reader to gain a full understanding of the technology, giving a valuable insight into the world’s most complex engineering systems. Key Features: Includes background information on the history of aerospace design and established optimization, geometrical and mathematical modelling techniques, setting recent engineering developments in a relevant context. Examines the latest methods such as evolutionary and response surface based optimization, adjoint and numerically differentiated sensitivity codes, uncertainty analysis, and concurrent systems integration schemes using grid-based computing. Methods are illustrated with real-world applications of structural statics, dynamics and fluid mechanics to satellite, aircraft and aero-engine design problems. Senior undergraduate and postgraduate engineering students taking courses in aerospace, vehicle and engine design will find this a valuable resource. It will also be useful for practising engineers and researchers working on computational approaches to design.
Download or read book 04 2370 04 2473 written by and published by . This book was released on 2004 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Impact of Advances in Computing and Communications Technologies on Chemical Science and Technology written by National Research Council and published by National Academies Press. This book was released on 1999-08-31 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemical Sciences Roundtable provides a forum for discussing chemically related issues affecting government, industry and government. The goal is to strengthen the chemical sciences by foster communication among all the important stakeholders. At a recent Roundtable meeting, information technology was identified as an issue of increasing importance to all sectors of the chemical enterprise. This book is the result of a workshop convened to explore this topic.
Download or read book Biomolecular Simulations in Structure Based Drug Discovery written by Francesco L. Gervasio and published by John Wiley & Sons. This book was released on 2019-04-29 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to applying the power of modern simulation tools to better drug design Biomolecular Simulations in Structure-based Drug Discovery offers an up-to-date and comprehensive review of modern simulation tools and their applications in real-life drug discovery, for better and quicker results in structure-based drug design. The authors describe common tools used in the biomolecular simulation of drugs and their targets and offer an analysis of the accuracy of the predictions. They also show how to integrate modeling with other experimental data. Filled with numerous case studies from different therapeutic fields, the book helps professionals to quickly adopt these new methods for their current projects. Experts from the pharmaceutical industry and academic institutions present real-life examples for important target classes such as GPCRs, ion channels and amyloids as well as for common challenges in structure-based drug discovery. Biomolecular Simulations in Structure-based Drug Discovery is an important resource that: -Contains a review of the current generation of biomolecular simulation tools that have the robustness and speed that allows them to be used as routine tools by non-specialists -Includes information on the novel methods and strategies for the modeling of drug-target interactions within the framework of real-life drug discovery and development -Offers numerous illustrative case studies from a wide-range of therapeutic fields -Presents an application-oriented reference that is ideal for those working in the various fields Written for medicinal chemists, professionals in the pharmaceutical industry, and pharmaceutical chemists, Biomolecular Simulations in Structure-based Drug Discovery is a comprehensive resource to modern simulation tools that complement and have the potential to complement or replace laboratory assays for better results in drug design.
Download or read book Models Databases and Simulation Tools Needed for Realization of Integrated Computational Mat Eng ICME 2010 written by Steven M. Arnold and Terry T. Wong, Editors and published by ASM International. This book was released on 2011 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Change Transformation and Development written by J. Stan Metcalfe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: For as long as one can remember, the edifice of the neoclassical economic syn thesis has been under attack. Critiques have focused on the extreme unreality of the assumptions that underpin the Arrow-Debreu theorems of welfare economics. They have queried the excessive formalism of the edifice, and the lack of practical significance of many of the results.They have castigated the neoclassical synthesis for its internal incoherence (lacking an independent theory of capital, for example, one of the favorite topics of the Cambridge school), its lack of a dynamic element, its non-evolutionary character, its lack of any conception of "market process" and so the list could be continued (Blaug, 1997). Through all this, the neoclassi cal synthesis remains as strong as ever, impervious it seems to these or any other attacks. In this paper a different tack is taken. The neoclassical edifice is left alone, standing as a representation of what goes on in a certain kind ofeconomy- namely the economy wheregoods and services are producedand exchanged. The paper then introduces another kind of economy, namely an economy of productive entities called "resources"- that are needed to produce the economyofgoods and services.
Download or read book Commerce Justice Science and Related Agencies Appropriations for 2014 written by United States. Congress. House. Committee on Appropriations. Subcommittee on Commerce, Justice, Science, and Related Agencies and published by . This book was released on 2013 with total page 1180 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Journal of Research of the National Bureau of Standards written by United States. National Bureau of Standards and published by . This book was released on 1985 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Interdisciplinary Applications of Agent Based Social Simulation and Modeling written by Adamatti, Diana Francisca and published by IGI Global. This book was released on 2014-04-30 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Social simulation can be a difficult discipline to encompass fully. There are many methods, models, directions, and theories that can be discussed and applied to various social sciences. Anthropology, sociology, political science, economy, government, and management can all benefit from social simulation. Interdisciplinary Applications of Agent-Based Social Simulation and Modeling aims to bring a different perspective to this interdisciplinary topic. This book presents current discussions and new insights on social simulation as a whole, focusing on its dangers, pitfalls, deceits, and challenges. This book is an essential reference for researchers in this field, professionals using social simulation, and even students studying this discipline.
Download or read book Product and Process Design written by Jan Harmsen and published by Walter de Gruyter GmbH & Co KG. This book was released on 2024-05-20 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Product and process design - driving sustainable innovation" is the 2nd edition of a comprehensive textbook for product and process design courses at BSc, MSc, EngD, and PhD level. It covers both heuristics based design methods as well as systems engineering approaches. It contains specific methods to co-design products and processes, so that both designs are better than when these designs are made separately. This integrated combination makes the book unique. For making designs that contribute to the Sustainable Development Goals of the United Nations specific methods are provided for the People, Planet, and Prosperity dimensions. This second edition of the book includes examples and exercises for each design method, which makes it very suitable for teaching purposes. The book is furthermore of interest to industrial process and product developers for many industry branches as it provides methods for design, modelling, and experimental validation for each innovation stage. It is also very useful for R&D managers as it provides guidelines for essential activities in each innovation stage (discovery, concept, feasibility, development, detailed engineering), leading to successful implementations of new processes and new products.
Download or read book Driving Scientific and Engineering Discoveries Through the Integration of Experiment Big Data and Modeling and Simulation written by Jeffrey Nichols and published by Springer Nature. This book was released on 2022-03-09 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the revised selected papers of the 21st Smoky Mountains Computational Sciences and Engineering Conference, SMC 2021, held in Oak Ridge, TN, USA*, in October 2021. The 33 full papers and 3 short papers presented were carefully reviewed and selected from a total of 88 submissions. The papers are organized in topical sections of computational applications: converged HPC and artificial intelligence; advanced computing applications: use cases that combine multiple aspects of data and modeling; advanced computing systems and software: connecting instruments from edge to supercomputers; deploying advanced computing platforms: on the road to a converged ecosystem; scientific data challenges. *The conference was held virtually due to the COVID-19 pandemic.
Download or read book Woods Danielson and Harris Nominations written by United States. Congress. Senate. Committee on Energy and Natural Resources and published by . This book was released on 2011 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cyberinfrastructure Vision for 21st Century Discovery written by and published by . This book was released on 2007 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Computational Biology in Drug Discovery and Repurposing written by Rajani Sharma and published by CRC Press. This book was released on 2024-08-16 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new book takes an in-depth look at the emerging and prospective field of computational biology and bioinformatics, which possesses the ability to analyze large accumulated biological data collected from sequence analysis of proteins and genes and cell population with an aim to make new predictions pertaining to drug discovery and new biology. The book explains the basic methodology associated with a bioinformatics and computational approach in drug designing. It then goes on to cover the implementation of computational programming, bioinformatics, pharmacophore modeling, biotechnological techniques, and pharmaceutical chemistry in designing drugs. The major advantage of intervention of computer language or programming is to cut down the number of steps and costs in the field of drug designing, reducing the repeating steps and saving time in screening the potent component for drug or vaccine designing. The book describes algorithms used for drug designing and the use of machine learning and AI in drug delivery and disease diagnosis, which are valuable in clinical decision-making. The implementation of robotics in different diseases like stroke, cancer, COVID-19, etc. is also addressed. Topics include machine learning, AI, databases in drug design, molecular docking, bioinformatics tools, target-based drug design, and immunoinformatics, chemoinformatics, and nanoinformatics in drug design. Drug repurposing in drug design in general as well as for specific diseases, including cancer, Alzheimer’s disease, tuberculosis, COVID-19, etc., is also addressed in depth.
Download or read book Quantum Chemistry in the Age of Machine Learning written by Pavlo O. Dral and published by Elsevier. This book was released on 2022-09-16 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantum chemistry is simulating atomistic systems according to the laws of quantum mechanics, and such simulations are essential for our understanding of the world and for technological progress. Machine learning revolutionizes quantum chemistry by increasing simulation speed and accuracy and obtaining new insights. However, for nonspecialists, learning about this vast field is a formidable challenge. Quantum Chemistry in the Age of Machine Learning covers this exciting field in detail, ranging from basic concepts to comprehensive methodological details to providing detailed codes and hands-on tutorials. Such an approach helps readers get a quick overview of existing techniques and provides an opportunity to learn the intricacies and inner workings of state-of-the-art methods. The book describes the underlying concepts of machine learning and quantum chemistry, machine learning potentials and learning of other quantum chemical properties, machine learning-improved quantum chemical methods, analysis of Big Data from simulations, and materials design with machine learning. Drawing on the expertise of a team of specialist contributors, this book serves as a valuable guide for both aspiring beginners and specialists in this exciting field. Compiles advances of machine learning in quantum chemistry across different areas into a single resource Provides insights into the underlying concepts of machine learning techniques that are relevant to quantum chemistry Describes, in detail, the current state-of-the-art machine learning-based methods in quantum chemistry
