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Book Abnormal Nutrition in the Human Articular Cartilages

Download or read book Abnormal Nutrition in the Human Articular Cartilages written by Peter Redfern and published by . This book was released on 1850 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Nutrition of Articular Cartilage in Relation to Its Development

Download or read book The Nutrition of Articular Cartilage in Relation to Its Development written by Brian McKibbin and published by . This book was released on 1968 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Effects of a High fat Diet on Cartilage in the Femoro tibial Joint of Young Adult Rats

Download or read book The Effects of a High fat Diet on Cartilage in the Femoro tibial Joint of Young Adult Rats written by Samuel sinclair Hayson and published by . This book was released on 2016 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a major risk factor in the development of many diseases, including those of the musculoskeletal system such as osteoarthritis (OA). Recent studies of the knee joint of severally obese children detected articular cartilage (AC) lesions, the significance of which, in long-term risks of OA in adults, is not known. Using a rat model, this thesis project aimed to test the hypothesis that a high-fat (HF) diet would result in abnormalities in the femoro-tibial joint (FTJ) cartilages. It also examined the potential effect of exercise in preventing the effects of diet-induced obesity on FTJ cartilage. Upon weaning, 40 male Sprague-Dawley rats were fed a Chow (18% kal fat) or HF (45% kcal fat) diet. At 63 days half of each group was allocated to either spontaneous cage activity (SED) or to free access to an exercise wheel (EX), resulting in 4 groups (Chow-SED, HF-SED, Chow-EX, HF-EX). Body composition was assessed using dual-energy X-ray absorptiometry (DEXA), and fasting plasma leptin and insulin concentrations using ELISA. Femoro-tibial joint samples were processed for histological examination, stained with toluidine blue, and assessed for cartilage abnormalities. Epiphyseal growth cartilage (EGC) was graded using a modified cartilage grading protocol. Type X collagen within the EGC was assessed using immunohistochemistry. Pearson’s correlation was conducted between body composition, leptin concentration and the presence of cartilage abnormalities. Body mass, percentage body fat, and fasting plasma leptin and insulin concentrations were higher in HF than Chow-fed animals, and lower in exercised than in nonexercised animals. There was no evidence that HF diet or exercise was associated with hyaline articular cartilage (HAC) abnormality. Epiphyseal growth cartilage abnormalities consistent with the disease osteochondrosis (OC) were observed. There were significantly greater numbers of osteochondritic lesions in HF-SED and HF-EX animals compared to Chow control groups. Type X collagen staining was also present within the abnormalities of the epiphyseal cartilage, consistent with a disruption in endochondral ossification. Body weight (p=0.006), percentage body fat (p=0.002) and fasting plasma leptin concentration (p=0.027) were significantly correlated with the presence of abnormalities in the epiphyseal growth cartilage. This is the first known study to observe abnormalities in the EGC of young adult rats exposed to a HF diet. Both the mechanism leading to the formation of osteochondral defects in the young rat, and features of a HF diet that appear to exacerbate formation of EGC abnormalities need to be established before translation and comparison to cartilage lesions in young people can be achieved.

Book Articular Cartilage Nutrition

Download or read book Articular Cartilage Nutrition written by Ragnar Ekholm and published by . This book was released on 1951 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book A Treatise on Diseases of the Joints

Download or read book A Treatise on Diseases of the Joints written by Richard Barwell and published by . This book was released on 1861 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Principles and Practice of Surgery

Download or read book The Principles and Practice of Surgery written by William Pirrie and published by . This book was released on 1852 with total page 980 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book A Treatise on Diseases of the Joints

Download or read book A Treatise on Diseases of the Joints written by Richard Barwell (F.R.C.S.) and published by . This book was released on 1881 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book A Treatise on Diseases of the Joints  Etc

Download or read book A Treatise on Diseases of the Joints Etc written by Richard BARWELL (F.R.C.S.) and published by . This book was released on 1861 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Surgeon s Vade Mecum

Download or read book The Surgeon s Vade Mecum written by Robert Druitt and published by . This book was released on 1878 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Principles of Regenerative Medicine

Download or read book Principles of Regenerative Medicine written by Anthony Atala and published by Academic Press. This book was released on 2010-12-16 with total page 1203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. - Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology - The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine - New discoveries from leading researchers on restoration of diseased tissues and organs

Book The Lancet

    Book Details:
  • Author :
  • Publisher :
  • Release : 1857
  • ISBN :
  • Pages : 688 pages

Download or read book The Lancet written by and published by . This book was released on 1857 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book A Treatise on Diseases of the Joints

Download or read book A Treatise on Diseases of the Joints written by Richard Barwell and published by BoD – Books on Demand. This book was released on 2024-02-25 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reprint of the original, first published in 1881.

Book Association medical journal

    Book Details:
  • Author : Provincial Medical and Surgical Association
  • Publisher :
  • Release : 1854
  • ISBN :
  • Pages : 1218 pages

Download or read book Association medical journal written by Provincial Medical and Surgical Association and published by . This book was released on 1854 with total page 1218 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Journal of Anatomy

Download or read book Journal of Anatomy written by and published by . This book was released on 1890 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Selected Monographs  Kussmaul and Tenner on Epileptiform Convulsions from Haemorrhage  Wagner on the Resection of Bones and Joints  Graefe s Three Memoirs on Iridectomy in Iritis  Choroiditis  and Glaucoma

Download or read book Selected Monographs Kussmaul and Tenner on Epileptiform Convulsions from Haemorrhage Wagner on the Resection of Bones and Joints Graefe s Three Memoirs on Iridectomy in Iritis Choroiditis and Glaucoma written by New Sydenham Society (London) and published by . This book was released on 1859 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: